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52 results about "Nausea sickness" patented technology

Nausea is a non-specific symptom, which means that it has many possible causes. Some common causes of nausea are motion sickness, dizziness, migraine, fainting, low blood sugar, gastroenteritis (stomach infection) or food poisoning.

Anesthesia reviving room risk assessment system for postoperative nausea and vomiting prediction

The invention discloses an anesthesia reviving room risk assessment system for postoperative nausea and vomiting prediction, relates to the technical field of postoperative nausea and vomiting prediction, and aims to perform multi-modal fusion on clinical features of a patient and brain function signals to realize basic probability calculation of postoperative nausea and vomiting risks, and introduce real-time dynamic physiological parameters as regulatory factors to realize postoperative nausea and vomiting risk prediction. And performing adaptive adjustment on the basic prediction result to generate a comprehensive risk probability value. The system can collect and process data in real time after a patient enters an anesthesia reviving room, and dynamic and personalized risk assessment is achieved. Compared with a traditional scoring method which only depends on static clinical features, the method has the advantages that tiny fluctuation of the postoperative physiological state of the patient can be captured, prediction precision and timeliness can be improved, clear decision support can be provided for nursing staff, and therefore preventive intervention measures are optimized, and the occurrence rate of complications is reduced.
Owner:LIUZHOU PEOPLES HOSPITAL

Intelligent nursing intervention system and method for nausea and vomiting after pulmonary operation

The invention relates to the technical field of intelligent nursing, in particular to an intelligent nursing intervention system and method for nausea and vomiting after a pulmonary operation. The analysis of nausea and vomiting performance is established on the basis of continuous and quantifiable indexes, the sensitivity of judging a risk trend is improved, a risk change path is identified through a long-short-term memory neural network, an influence rule of intervention intensity on a nausea and vomiting evolution trend is accurately described, stage prediction of a nursing intervention effect is realized, and the risk prediction accuracy is improved. Structural optimization is performed on an intervention time sequence and nursing task allocation and execution rhythm through a convolutional neural network, an intervention rhythm path is recombined in combination with resource adaptation information, the coverage density of intervention measures for risk periods is enhanced, integrated response of nursing resources in a high-sensitivity interval is promoted, and synchronous optimization of task allocation and time sequence matching is realized.
Owner:YIXING PEOPLES HOSPITAL

Traditional Chinese medicine composition for alleviating gastrointestinal toxicity caused by chemotherapy

ActiveCN116942748BDispersion deliveryDigestive systemGastrointestinal toxicityMedicinal herbs
A traditional Chinese medicine composition for alleviating gastrointestinal toxic side effects caused by chemotherapy, the traditional Chinese medicine composition for daily administration is prepared from the following weight ratio of traditional Chinese medicine formula: Taizishen 20-30g, Fuling 10-15g, Fried Baizhu 10-15g, Zhigancao 5-10g, Jiangbanxia 5-10g, Chenpi 5-15g. The formula can effectively alleviate the gastrointestinal toxic side effects caused by chemotherapy, such as nausea, vomiting, diarrhea, poor appetite, etc.
Owner:XIYUAN HOSPITAL OF CHINA ACAD OF CHINESE MEDICAL SCI

Hangover-alleviating probiotic and use thereof

A Limosilactobacillus fermentum strain capable of alleviating a hangover and the use thereof. The strain is at least one strain of Limosilactobacillus fermentum ibiome020, Limosilactobacillus fermentum ibiome021 and Limosilactobacillus fermentum ibiome022 respectively deposited with deposit numbers of CCTCC NO: M 2024188, CCTCC NO: M 2024222 and CCTCC NO: M 2024189. The Limosilactobacillus fermentum is a natural bacterium derived from the intestine of a healthy human and has high safety; can alleviate chronic / acute alcoholism, alcoholic intestinal damage or alcoholic liver damage; can accelerate the metabolism of ethanol and / or acetaldehyde, and delay the onset of intoxication; can shorten the sobering-up time; can reduce the mortality caused by drinking alcohol; can reduce the liver index; can lower the level of AST and / or ALT in serum; can alleviate discomfort caused by ethanol and / or acetaldehyde, and mitigate symptoms such as dizziness, headache, nausea and vomiting, and hangover after drinking alcohol; can ameliorate oxidative stress caused by alcohol, and increase the level of GSH in the liver; and also has excellent resistance to gastrointestinal fluid and bile salt, and can adapt to the complex environment within the body.
Owner:IBIOME BIOTECHNOLOGY CO LTD

Portable temperature-controllable ginger moxibustion device for preventing or arresting vomiting of tumor patient

The invention relates to the technical field of ginger moxibustion, in particular to a portable temperature-controllable ginger moxibustion device for arresting vomiting of tumor patients, which comprises a shell, a tube is fixedly connected to the inner side wall of the shell, a pore plate is fixedly connected to the bottom of the tube, a temperature sensor is mounted on the inner side wall of the tube, and a cover is in threaded connection to the top of the shell. A cylinder is fixedly connected to the bottom of the cover body, and an electric heating rod is mounted at the bottom of the cylinder; the electric heating rod is used for simulating heating power of moxa in traditional ginger-separated moxibustion, controllable heating power is used for exciting drug efficacy of ginger of ginger slices on the pore plate, the synergistic effect mechanism that ginger penetrates through heating power and drug efficacy enters the acupoint is perfectly rescribed, the device is designed according to the core requirement of descending adverse-rising energy and arresting vomiting of tumor patients, the device can accurately act on related acupoints for arresting vomiting, and the effect is achieved. The symptoms of nausea and vomiting caused by chemoradiotherapy and the like are effectively relieved.
Owner:THE FIRST AFFILIATED HOSPITAL OF TIANJIN UNIV OF TRADITIONAL CHINESE MEDICINE

Traditional Chinese medicine composition for treating digestive tract reaction after malignant tumor operation, preparation and application

The invention relates to the field of traditional Chinese medicines, and discloses a traditional Chinese medicine composition for treating postoperative digestive tract reaction of malignant tumors, a preparation and application. The traditional Chinese medicine composition comprises the following active ingredient raw materials in parts by weight: 10-20 parts of fried codonopsis pilosula, 10-20 parts of fried bighead atractylodes rhizome, 10-20 parts of poria cocos, 1-10 parts of liquorice, 10-20 parts of fried endothelium corneum gigeriae galli, 15-25 parts of fried malt, 25-35 parts of adina rubella hance root, 25-35 parts of wild grape root, 15-25 parts of Chinese actinidia root and 15-25 parts of coix seed. The traditional Chinese medicine composition and the preparation can effectively treat patients with malignant tumor postoperative digestive tract reaction, effectively improve symptoms of abdominal distension, stomachache, nausea, vomiting, diarrhea, constipation, anorexia, sour regurgitation, oral cavity / throat dryness and the like of the patients, improve the life quality of the patients and have good safety.
Owner:ZHEJIANG ACAD OF TRADITIONAL CHINESE MEDICINE +1

Tumor patient nausea and vomiting evaluation device

The utility model discloses a tumor patient nausea and vomiting evaluation device, and particularly relates to the technical field of tumor patient nausea and vomiting evaluation, the tumor patient nausea and vomiting evaluation, the tumor patient nausea and vomiting evaluation device comprises a digital scoring ruler and a facial expression scoring ruler, the bottom end of the digital scoring ruler is provided with a cavity adapted to the sliding placement of the facial expression scoring ruler, and the side end of the facial expression scoring ruler is provided with an accommodating groove; and rolling wheels are rotationally mounted in the accommodating grooves and are in rolling fit with the side walls of the cavities. According to the device, the facial expression scoring ruler is arranged in the digital scoring ruler in a sleeving manner, so that the device is convenient for medical staff to carry and also convenient for the medical staff to select an evaluation tool which is most suitable for a patient to use.
Owner:赣州市人民医院

Methods of using homotaurine and analogs thereof for the treatment of glucagon-like peptide 1 receptor agonist induced gastrointestinal side effects

Disclosed are the use of methods for reducing one or more gastrointestinal side effects in a subject receiving glucagon-like peptide-1 (GLP-1) receptor agonist (RA) therapy. The methods include administering to a subject receiving GLP-1 RA therapy an amount of homotaurine-like gastrointestinal distress-relieving (HTL-GIDR) composition effective to reduce gastrointestinal side effects of GLP-1 RA therapy, e.g., nausea, vomiting, and constipation. Generally, the HTL-GIDR composition can be homotaurine or a homotaurine analog such as acamprosate calcium and valiltramiprosate (ALZ-801), or a combination thereof. Furthermore, the HTL-GIDR composition may facilitate tolerance during the GLP-1 RA dose escalation phases and enable administration of higher GLP-1 RA doses, thereby enhancing therapeutic outcomes in conditions including diabetes, obesity, and neurodegenerative diseases.
Owner:UNIV OF TARTU

Traditional Chinese medicine composition for treating chemotherapy-related nausea and vomiting, acupoint patch and preparation method

The invention discloses a traditional Chinese medicine composition for treating chemotherapy-related nausea and vomiting, an acupoint patch and a preparation method, and belongs to the technical field of traditional Chinese medicine research. According to a fine-tuning external application formula, acupoint external application is achieved, medicine transdermal absorption is matched with acupoints to stimulate channel and qi combination, and the effect is special and strong; the medication route is changed, oral administration is avoided, and the gastrointestinal burden is relieved. Aromatic traditional Chinese medicines are used for guiding channels, promoting qi circulation, dredging collaterals and promoting transdermal absorption; and the aromatic traditional Chinese medicines enter spleen and stomach channels, enlivene spleen and please stomach, and are helpful for improving gastrointestinal reactions such as nausea and vomiting. The acupoint patch is simple and easy to operate and learn, has a high degree of recognition by the masses, and is easy to popularize in western medicine hospitals and primary hospitals.
Owner:WUXI HOSPITAL OF CHINESE MEDICINE

Traditional Chinese medicine composition for treating warm disease clinically belonging to same disease of defensive qi as well as preparation method and application of traditional Chinese medicine composition

The invention discloses a traditional Chinese medicine composition for treating a warm disease clinically belonging to the same disease of defensive qi and a preparation method and application thereof.The traditional Chinese medicine composition is prepared from, by weight, 5-35 parts of bupleurum chinense, 9-50 parts of scutellaria baicalensis, 9-50 parts of artemisia apiacea, 5-35 parts of radix paeoniae rubra, 5-35 parts of moutan bark and 4-26 parts of folia perillae acutae. According to the traditional Chinese medicine composition, the effects of all the medicines are utilized to generate a synergistic effect, and the effects of relieving fever, eliminating evil and detoxifying are achieved together. The traditional Chinese medicine composition is used for treating fever or hyperpyrexia, slight aversion to wind-cold, headache, sweating, thirst, cough and pharyngalgia caused by cold, viral cold and upper respiratory tract infection febrile disease defensive qi, and can be accompanied by nausea, vomiting, neck stiffness, rash appearance, red eye swelling and pain and the like, so that the febrile disease is effectively treated.
Owner:HEBEI PING AN HEALTH GRP CO LTD

Chemotherapy-induced nausea and vomiting condition recording board

The utility model discloses a record board for nausea and vomiting conditions caused by chemotherapy, and relates to the field of medical instruments. The recording board comprises a panel and a marking block, wherein the panel is provided with two condition information areas and two condition recording grooves; the condition information area comprises four condition grading areas; four condition grading areas of one condition information area respectively have nausea grade information, and four condition grading areas of the other condition information area respectively have vomiting grade information; the condition recording grooves and the condition information areas are arranged in a one-to-one correspondence mode, each condition recording groove comprises a lower transverse groove, a communicating vertical groove, four communicating transverse grooves and four recording vertical grooves, the recording vertical grooves and the condition grading areas are arranged in a one-to-one correspondence mode and are close to the condition grading areas, and the communicating vertical grooves are located on the outer sides of the recording vertical grooves; the communicating transverse groove communicates with the upper end of the recording vertical groove and the communicating vertical groove, and the lower transverse groove is located at the lower end of the communicating vertical groove and forms a T-shaped groove together with the communicating vertical groove; and seven marking blocks are placed in each condition recording groove.
Owner:WEST CHINA HOSPITAL SICHUAN UNIV

Traditional Chinese medicine composition for treating stomach illness and preparation method thereof

PendingCN120000744APowder deliveryAntipyreticNausea sicknessStomach Pain
The invention relates to the field of traditional Chinese medicine formulas, and particularly discloses a traditional Chinese medicine composition for treating stomach illness and a preparation method thereof, and each dose of the traditional Chinese medicine composition is prepared from the following components by mass: 30-50 g of rhizoma bletillae, 30 g of radix cynanchi bungei, 20-30 g of cuttle bone, 20-30 g of pseudo-ginseng, 20 g of rhizoma corydalis and 20 g of radix aucklandiae. A method for preparing the traditional Chinese medicine composition for treating stomach diseases comprises the following steps: step 1, mixing the rhizoma bletillae, the radix cynanchi bungei, the cuttle bone, the pseudo-ginseng, the rhizoma corydalis and the radix aucklandiae in proportion, and crushing twice by adopting a high-speed crusher; the traditional Chinese medicine prepared by the invention has a good treatment effect on stomachache, such as gastric ulcer, duodenal ulcer, chronic gastritis, gastrorrhagia, stomachache, stomachache, dyspepsia and the like; through the synergistic effect of various traditional Chinese medicines, the traditional Chinese medicine composition can effectively relieve clinical symptoms such as stomachache, stomachache, sour regurgitation, nausea and vomiting, and meanwhile, can promote the repair of gastric mucosa and the healing of ulcer surfaces.
Owner:潘秀文

Medicine solution composition, preparation method thereof, nasal spray and application

The invention relates to the technical field of biological medicine, in particular to a medicine solution composition, a preparation method thereof, a nasal spray and application. The medicine solution composition comprises a medicine active component, an osmotic pressure regulator, a pH regulator and water. The active pharmaceutical ingredient comprises ondansetron or a pharmaceutically acceptable salt of ondansetron. The medicine solution composition provided by the invention can be quickly absorbed into blood through nasal mucosa, reaches a peak within 5-10 minutes after being administered through nasal spray administration, is expected to take effect quickly, can help a patient to deal with nausea and vomiting caused by cytotoxic chemotherapy and radiotherapy in time and be used for preventing postoperative nausea and vomiting (PONV), and is good in stability.
Owner:GUANGZHOU NOVAKEN PHARM CO LTD

A traditional Chinese medicine compound composition for treating hypertension-induced dizziness and its preparation method

The present invention relates to the technical field of traditional Chinese medicine for treating hypertension vertigo, and particularly relates to a traditional Chinese medicine compound composition for treating hypertension vertigo and a preparation method thereof. Calculated by mass parts, the raw materials of the traditional Chinese medicine compound composition for treating hypertension vertigo include: calcined magnetite 30 - 120 parts, eucommia ulmoides 15 - 60 parts, gastrodia elata 20 - 180 parts, apocynum venetum leaves 15 - 120 parts, cyathula officinalis 10 - 40 parts, pinellia ternata processed with rhizoma zingiberis recens 8 - 30 parts, stir-fried atractylodes macrocephala 15 - 120 parts, alisma orientale 10 - 120 parts, pueraria lobata 30 - 120 parts, corn stigma 10 - 60 parts, and stevia rebaudiana 10 - 40 parts. The traditional Chinese medicine compound composition of the present invention has a good antihypertensive effect on patients with hypertension vertigo, can significantly improve the clinical symptoms of patients with hypertension vertigo such as dizziness and heaviness in the head, dizziness and blurred vision, dimmed vision, tinnitus and bitter taste in the mouth, nausea and vomiting, limb numbness, restlessness and difficulty in falling asleep, etc. The curative effect on treating hypertension vertigo (syndrome of wind-phlegm disturbing upward) is definite, and the medication is safe and reliable.
Owner:JIANGSU PROVINCE INST OF TRADITIONAL CHINESE MEDICINE

A traditional Chinese medicine composition with antiemetic effect and a preparation method thereof

ActiveCN118477164BDigestive systemUnknown materialsAntiemetic EffectNausea sickness
The present application belongs to the technical field of traditional Chinese medicine, and particularly relates to a traditional Chinese medicine composition with an antiemetic effect and a preparation method thereof. The traditional Chinese medicine composition contains perilla leaf, Coptis chinensis, Amomum villosum, Saussurea lappa, Pinellia ternata, ginger, Chinese yam and honey. The traditional Chinese medicine composition has a good relieving and treating effect on pregnancy vomiting through pharmacological experiments and clinical use verification. The clinical treatment rate of pregnancy vomiting reaches 92.86%, and the traditional Chinese medicine composition can effectively relieve the clinical symptoms of patients, such as nausea and vomiting, dizziness, anorexia, food entering the stomach and then vomiting, and the like. The preparation process is simple, the traditional Chinese medicine composition can be further produced, and has a wide market prospect.
Owner:HENAN UNIV OF CHINESE MEDICINE

A method for treating postoperative nausea and vomiting by using buccal needle combined with triple antiemetic

PendingCN122351257AAntiemetic EffectNausea sickness
This invention provides a method for treating postoperative nausea and vomiting using buccal acupuncture combined with a triple antiemetic regimen. The method employs a combined intervention of buccal acupuncture and a triple antiemetic regimen. The triple regimen consists of a 5-HT3 receptor antagonist, a glucocorticoid, and a dopamine receptor antagonist, administered intravenously in two separate doses. The buccal acupuncture uses CA-2 (upper jiao), CA-3 (middle jiao), and CA-4 (lower jiao) as core acupoints, with auxiliary and reinforcing acupoints added based on the surgical site and high-risk groups. A standardized procedure of pecking stimulation is applied, along with a corresponding postoperative remedial antiemetic medication regimen. This invention organically combines multi-target drug blockade with buccal acupuncture's visceral regulation, synergistically enhancing the antiemetic effect, reducing the incidence of nausea and vomiting, and decreasing the need for remedial medication. The regimen is highly standardized, widely adaptable, and can meet the postoperative nausea and vomiting control needs of various surgeries and high-risk groups. It exhibits good safety, strong repeatability, and high clinical application value.
Owner:JIANGSU UNIV AFFILIATED PEOPLES HOSPITAL

Methods of treating nausea and vomiting disorders using anti-GFRAL antibodies

The present disclosure relates generally to methods of treating, preventing, or reducing nausea, vomiting, or a combination thereof, hyperemesis gravidarum (HG), nausea gravidarum and vomiting (NVP), or sequelae thereof in a human subject in need thereof, the methods comprise administering to the human subject a therapeutically effective amount of an antibody that specifically binds to a human glial cell line derived neurotrophic factor family receptor alpha-like (GFRAL).
Owner:NGM BIOPHARMACEUTICALS INC

An external-use traditional Chinese medicine composition for treating nausea and vomiting caused by brain tumor chemotherapy, an external-use medicine, an external-use patch, an acupoint patch, and a preparation method and application thereof

This invention belongs to the field of traditional Chinese medicine technology, and relates to a topical Chinese medicine composition, topical drug, topical patch, acupoint patch, and preparation method and application for treating nausea and vomiting caused by chemotherapy for intracranial tumors. The Chinese medicine composition consists of the following raw materials in parts by weight: 1-2 parts of Ligusticum chuanxiong, 1-2 parts of Gastrodia elata, 2-4 parts of Uncaria rhynchophylla, 1-2 parts of Citrus aurantium, 1-2 parts of Sinapis alba, 1-2 parts of Clematis chinensis, 0.5-1 part of Melia toosendan, 0.5-1 part of Panax ginseng, 1-2 parts of Pinellia ternata, 1-2 parts of Albizia julibrissin bark, 0.5-1 part of Lentinus edodes, and 1-2 parts of Astragalus membranaceus. This Chinese medicine composition has the effects of relieving nausea and vomiting, soothing the liver and strengthening the spleen, detoxifying and eliminating turbidity, calming the liver and extinguishing wind, and calming the mind and soothing the nerves. It not only effectively controls the nausea and vomiting symptoms caused by chemotherapy for intracranial tumors, but also harmonizes the body's Qi and organ functions. The Chinese medicine composition has a simple formula, widely available ingredients, and a simple preparation method; it is for topical application, convenient for clinical use, and has low adverse reactions.
Owner:TIANJIN TUMOR HOSPITAL

Application of nifurazil or pharmaceutically acceptable derivative thereof and pharmaceutical composition

The invention provides application of nifurazide or a pharmaceutically acceptable derivative thereof and a pharmaceutical composition, and belongs to the technical field of biological medicines. The application comprises application of nifurazil in preparation of drugs for reducing food intake and / or inhibiting appetite. The nifurazil does not depend on blood sugar regulation and intestines and stomach, and does not cause side effects of nausea and vomiting; the action target of the nifurazil is not located in the peripheral nervous system but acts on the central nervous system, and the nifurazil can be used for remarkably reducing the intake of common food and high-fat food of mice and inhibiting the appetite of the mice in a mode of activating Glp1-r, so that the weight of the obese mice is remarkably reduced. Therefore, the nifurazil has the potential of treating the obesity and can be applied to preparation of the medicine for treating the obesity.
Owner:UNIV OF SCI & TECH OF CHINA

Composition for relieving nausea and vomiting symptoms caused by chemotherapy and application thereof

The invention belongs to the technical field of medicine preparation, and particularly relates to a composition for relieving nausea and vomiting symptoms caused by chemotherapy and application of the composition. 38-42 parts of lily, 25-30 parts of black dates, 17-23 parts of herba violae, 15-19 parts of pumpkins, 9-13 parts of fructus gardeniae and 5-10 parts of flaxseeds are specifically combined, all the raw materials can achieve a synergistic effect, gastrointestinal mucosa is protected, irritation of chemotherapeutic drugs to gastrointestinal tracts is reduced, and the occurrence rate of vomiting is reduced; in addition, the raw materials can regulate the immune function of the body, enhance the resistance of the body and relieve the adverse effect of chemotherapeutic drugs on the body, so that vomiting is indirectly relieved. Therefore, the composition provided by the invention can be used for preparing products for relieving nausea and vomiting symptoms caused by chemotherapy, the preparation method is simple and convenient, the vomiting symptoms can be prevented and treated in a targeted manner, and the pain of patients is greatly relieved.
Owner:THE SECOND HOSPITAL OF DALIAN MEDICAL UNIV

GLP-1R receptor agonist polypeptide compound and application thereof

The invention discloses a GLP-1R receptor agonist polypeptide compound and application thereof, and belongs to the field of polypeptide medicines, and the amino acid sequence of the GLP-1R polypeptide compound is H-X1-EGTFTSDVSYLEGQ-X2-X3-Bn-EFI-X4-X5-L-X6-RGRG. The invention further discloses a preparation method of the GLP-1R receptor agonist polypeptide compound. The GLP-1R polypeptide compound disclosed by the invention has a more remarkable agonistic effect on a human glucagon-like peptide-1 (GLP-1) receptor, not only has the effects of reducing blood glucose and reducing weight, but also has a longer half-life period and higher bioavailability, can avoid adverse reactions such as nausea and vomiting caused by long-term use of existing medicines, and has a good application prospect. The compound can be used as an effective raw material for preparing medicines for treating or preventing diabetes or weight-reducing medicines.
Owner:CHINA PHARM UNIV

Anti-vomiting hydrolyzed whey protein and preparation method thereof

The invention discloses anti-vomiting hydrolyzed whey protein and a preparation method thereof, and belongs to the technical field of food processing. The product provided by the invention reduces the digestion burden of protein and relieves the symptom of vomiting. According to the method disclosed by the invention, protein sequences are mutually crosslinked by virtue of a treatment mode of first fibration, second polymerization and final hydrolysis, and a hydrolyzed polypeptide sequence is changed, so that the abundance of the polypeptide SLAMAASDISLA in a hydrolysate is improved. The polypeptide has the characteristics of being easy to recognize by intestinal peptidase and relatively high in PepT1 affinity, the bioavailability of protein is improved, and the deamination proportion of unutilized amino acid is reduced, so that substances generating nitrogen-containing toxoid are reduced, the stimulation of toxin accumulation on gastrointestinal mucosa is relieved, and the symptoms of nausea, vomiting and the like of a user are avoided.
Owner:JIANGNAN UNIV

Traditional Chinese medicine composition for tonifying spleen and detoxifying as well as preparation method and application of traditional Chinese medicine composition

The invention provides a spleen-tonifying and detoxifying traditional Chinese medicine composition as well as a preparation method and application thereof, and belongs to the technical field of traditional Chinese medicines. The traditional Chinese medicine composition comprises a formula A and a formula B. The traditional Chinese medicine composition has a comprehensive conditioning effect and can relieve chemotherapy side effects, improve intestinal flora distribution, promote intestinal health, enhance the chemotherapy effect and improve the disease control rate. Wherein the formula A focuses on tonifying spleen and regulating qi, and improving nausea, vomiting and other symptoms at the initial stage of chemotherapy, and the formula B is added with medicines for clearing away heat and toxic materials and promoting blood circulation to remove blood stasis on the basis, is suitable for patients with myelosuppression with cancer toxicity residue, and strengthens the effects of clearing away heat and toxic materials and removing stasis; the composition has a multi-target action mechanism, and through the combined action of multiple ways, the treatment effect is enhanced, and the side effect is reduced.
Owner:THE SECOND XIANGYA HOSPITAL OF CENT SOUTH UNIV

Massager for relieving and stopping vomiting in gynecological tumor chemotherapy

The invention belongs to the technical field of medical auxiliary instruments, and discloses a gynecological tumor chemotherapy relieving and vomiting stopping massager which comprises a seat body and a movable massage assembly, the seat body is connected with a seat back plate, the seat back plate is connected with a back massage assembly, a groove body and a fixing ring, and the back massage assembly comprises a first motor, a massage roller, a belt wheel and a transmission belt; the movable massage assembly comprises a bandage and a massage device, the massage device comprises a second motor, a massage base body, a fixed gear ring, a sun gear, a protective rubber sleeve and a planetary gear, the bandage is connected with a sliding block, and the sun gear and the planetary gear are both connected with massage balls; the back of a patient is massaged in a rolling mode through rotation of the massage roller of the back massage assembly so as to promote blood circulation and relieve muscle fatigue, different acupuncture points are massaged in a targeted mode through the massage device so as to regulate qi and blood circulation, and the functions of regulating yin and yang, dredging channels and collaterals, conditioning viscera and the like are achieved; therefore, nausea and vomiting of chemotherapy patients are relieved.
Owner:XINXIANG CENTER HOSPITAL

Application of sesquiterpenoids in relieving nausea and vomiting

This invention relates to the field of chemical pharmaceutical technology, specifically to the application of sesquiterpenoid compounds in relieving nausea and vomiting. The sesquiterpenoid compounds of this invention are cypressin and its analogues, racemates, stereoisomers, tautomers, isotope-labeled compounds, solvates, polymorphs, metabolites, prodrugs, or pharmaceutically acceptable salts thereof, having the following structures, wherein R1-R8 are as described in the claims and specification. These sesquiterpenoid compounds can reduce kaolin ingestion in pica rats and significantly alleviate nausea and vomiting symptoms induced by chemotherapeutic drugs such as cisplatin during tumor treatment. They can also relieve vomiting caused by gastrointestinal damage, inflammatory diseases, anorexia, etc. They can be used to prepare drugs for relieving / treating nausea and vomiting or to prepare foods that help protect the gastric mucosa.
Owner:LIAONING XINZHONG MODERN PHARMACEUTICAL CO LTD

Application of N-acetylglutamine in preparation of medicine for treating obesity or reducing obesity-related metabolic indexes or MAFLD

The invention discloses an application of N-Aceglutamide (NAG) in preparation of a medicine for treating obesity or relieving obesity-related metabolic indexes or metabolism-related fatty liver (MAFLD) (Metabolism-related Fatty Liver Disease). The invention further discloses an application of the N-Aceglutamide (NAG) in preparation of a medicine for treating obesity or relieving obesity-related metabolic indexes or metabolism-related fatty liver (MAFLD). According to the invention, the important application prospect of NAG in weight reduction and treatment of MAFLD diseases is shown for the first time, fat weight can be reduced, obesity can be treated, and NAG can significantly reduce fat tissue accumulation, promote lipolysis, inhibit adipogenesis and reduce serum triglyceride and free fatty acid levels. In animal models, NAG significantly reduces weight gain induced by high fat diet and improves body fat distribution. The NAG disclosed by the invention can effectively avoid side effects such as nausea, vomiting, constipation and the like caused by weight loss medicines such as appetite inhibition or food intake reduction, and an effective medicine is provided for MAFLD treatment.
Owner:JIANGSU PROVINCE HOSPITAL (THE FIRST AFFILIATED HOSPITAL OF NANJING MEDICAL UNIVERSITY)

Dual agonist polypeptide compound and pharmaceutical use thereof

The present invention belongs to the field of polypeptide pharmaceuticals, and provides a dual agonist polypeptide compound and the pharmaceutical use thereof. An amino acid sequence of a GIP-R and GLP-1R dual agonist polypeptide compound is: Y1-X1-EGTFTSDYSI-X2-LDKI-X3-Q-Bn-X4-X5-VQWLI-X6-GGPSSG-X7-PPPS, and the C-terminal amino acid is amidated. The GIP-R and GLP-1R dual agonist polypeptide compound has a more significant dual agonistic effect on human glucose-dependent insulinotropic polypeptide (GIP) and human glucagon-like peptide-1 (GLP-1) receptors. The compound not only has the effects of lowering blood sugar and reducing weight, but also has a longer half-life and a higher bioavailability. The compound can avoid adverse reactions such as nausea and vomiting caused by the long-term use of existing drugs, and thus can be used as an effective raw material for the preparation of a drug for treating or preventing diabetes or an anti-obesity drug.
Owner:CHINA PHARM UNIV

Chemotherapy auxiliary device for oncology department

This invention belongs to the field of medical auxiliary device technology and discloses a chemotherapy support device for oncology. It includes a seat body, a respiratory status detection device, and a controller. The seat body is connected to armrests, a Neiguan acupoint massage component, a Zusanli acupoint massage component, an abdominal heat therapy component, a headrest, and a speaker. The Neiguan acupoint massage component includes a base, a motor, a fixed gear ring, a sun gear, planetary gears, and massage balls. The Zusanli acupoint massage component includes an air pump and an airbag. The abdominal heat therapy component includes a strap, a medicine storage box, a heat therapy bag, and an electric heating wire. The respiratory status detection device includes a pressure sensor. This invention utilizes the Neiguan acupoint massage component to stimulate and massage the Neiguan acupoint, the Zusanli acupoint massage component to compress the Zusanli acupoint, and the abdominal heat therapy component to provide heat therapy to the abdomen, effectively relieving symptoms such as nausea and vomiting, numbness in the hands and feet, and abdominal cold pain after chemotherapy.
Owner:THE FIRST AFFILIATED HOSPITAL OF TIANJIN UNIV OF TRADITIONAL CHINESE MEDICINE

Traditional Chinese medicine composition for improving gastrointestinal motility disorder and preparation method thereof

The invention relates to the technical field of traditional Chinese medicines, in particular to a traditional Chinese medicine composition for improving gastrointestinal motility disorder and a preparation method thereof, and the traditional Chinese medicine composition is prepared from the following raw materials: fried malt, fried rice sprout, poria cocos, fructus amomi and liquorice. The traditional Chinese medicine composition disclosed by the invention can improve clinical symptoms such as postprandial fullness, early satiety, epigastric pain and epigastric discomfort caused by gastrointestinal motility disorder, epigastric burning feeling and epigastric spasmodic pain; insufficient gastric motility caused by gastrointestinal motility disorder is relieved, and nausea, vomiting, ozostomia, sour regurgitation or bitter regurgitation in the mouth are improved; the traditional Chinese medicine is used for treating weakness of spleen and stomach, and improving the symptoms of poor appetite, anorexia, fatigue, intolerance of cold, cold limbs and sweet excrement caused by stomach cold dull pain, stomach cold distention and fullness, warm and press liking.
Owner:LONGHUA HOSPITAL SHANGHAI UNIV OF TRADITIONAL CHINESE MEDICINE +1

Rehabilitation management method and system for nausea and vomiting of tumor chemotherapy patient

The invention provides a rehabilitation management method and system for nausea and vomiting of a tumor chemotherapy patient, and relates to the technical field of medical treatment. The main control chip can input the attribute characteristics of the patient, the medication characteristics of the chemotherapeutic drugs for the malignant tumors and the physiological characteristics of the first patient into a pre-trained first vomiting degree prediction model to predict the first vomiting degree of the patient; inputting the attribute characteristics of the patient and the first vomiting degree of the patient into a vomiting rehabilitation management strategy model, and determining each massage manipulation for the Neiguan point of the wrist of the patient, the massage sequence of each massage manipulation, and the massage duration, massage force and massage frequency of each massage manipulation; according to the determined massage sequence of each massage manipulation and the massage duration, massage force and massage frequency of each massage manipulation, the simulation massage hand is controlled to massage the Neiguan point of the wrist of the patient, and the nausea and vomiting symptoms caused after the malignant tumor patient takes chemotherapy drugs can be accurately prevented and improved.
Owner:THE AFFILIATED HOSPITAL OF XUZHOU MEDICAL UNIV