72 results about "Nausea sickness" patented technology

The invention discloses an anesthesia reviving room risk assessment system for postoperative nausea and vomiting prediction, relates to the technical field of postoperative nausea and vomiting prediction, and aims to perform multi-modal fusion on clinical features of a patient and brain function signals to realize basic probability calculation of postoperative nausea and vomiting risks, and introduce real-time dynamic physiological parameters as regulatory factors to realize postoperative nausea and vomiting risk prediction. And performing adaptive adjustment on the basic prediction result to generate a comprehensive risk probability value. The system can collect and process data in real time after a patient enters an anesthesia reviving room, and dynamic and personalized risk assessment is achieved. Compared with a traditional scoring method which only depends on static clinical features, the method has the advantages that tiny fluctuation of the postoperative physiological state of the patient can be captured, prediction precision and timeliness can be improved, clear decision support can be provided for nursing staff, and therefore preventive intervention measures are optimized, and the occurrence rate of complications is reduced.

The invention provides the aprepitant and palonosetron hydrochloride compound emulsion for injection, the compound emulsion has better stability, nausea and vomiting can be more conveniently and effectively prevented and treated, and the medication compliance of patients is improved.

The invention provides a traditional Chinese medicine composition for relieving chemotherapy side effects, traditional Chinese medicine compound essential oil and a preparation method and application thereof, and relates to the technical field of traditional Chinese medicines. The traditional Chinese medicine composition comprises the following raw materials in parts by weight: 1-9 parts of pericarpium citri reticulatae, 1-9 parts of pericarpium citri reticulatae viride, 1-9 parts of clove, 1-9 parts of fennel, 1-9 parts of ginger, 1-9 parts of pogostemon cablin and 1-9 parts of rhizoma atractylodis. The traditional Chinese medicine composition is mainly used for treating abdominal distension pain, nausea and vomiting caused by damp turbidity resistance and spleen and stomach disharmony through the effects of promoting qi circulation, removing dampness, strengthening the spleen and harmonizing the stomach. Experimental results show that the traditional Chinese medicine compound essential oil prepared from the traditional Chinese medicine composition can reduce allotriophagia behaviors of rats and improve ingestion and drinking habits, has a recovery effect on metabolite disorder caused by chemotherapy-related nausea and vomiting, and provides a theoretical basis for a supplementary treatment method of chemotherapy-related nausea and vomiting.

The invention relates to the technical field of intelligent nursing, in particular to an intelligent nursing intervention system and method for nausea and vomiting after a pulmonary operation. The analysis of nausea and vomiting performance is established on the basis of continuous and quantifiable indexes, the sensitivity of judging a risk trend is improved, a risk change path is identified through a long-short-term memory neural network, an influence rule of intervention intensity on a nausea and vomiting evolution trend is accurately described, stage prediction of a nursing intervention effect is realized, and the risk prediction accuracy is improved. Structural optimization is performed on an intervention time sequence and nursing task allocation and execution rhythm through a convolutional neural network, an intervention rhythm path is recombined in combination with resource adaptation information, the coverage density of intervention measures for risk periods is enhanced, integrated response of nursing resources in a high-sensitivity interval is promoted, and synchronous optimization of task allocation and time sequence matching is realized.

A traditional Chinese medicine composition for alleviating gastrointestinal toxic side effects caused by chemotherapy, the traditional Chinese medicine composition for daily administration is prepared from the following weight ratio of traditional Chinese medicine formula: Taizishen 20-30g, Fuling 10-15g, Fried Baizhu 10-15g, Zhigancao 5-10g, Jiangbanxia 5-10g, Chenpi 5-15g. The formula can effectively alleviate the gastrointestinal toxic side effects caused by chemotherapy, such as nausea, vomiting, diarrhea, poor appetite, etc.

A Limosilactobacillus fermentum strain capable of alleviating a hangover and the use thereof. The strain is at least one strain of Limosilactobacillus fermentum ibiome020, Limosilactobacillus fermentum ibiome021 and Limosilactobacillus fermentum ibiome022 respectively deposited with deposit numbers of CCTCC NO: M 2024188, CCTCC NO: M 2024222 and CCTCC NO: M 2024189. The Limosilactobacillus fermentum is a natural bacterium derived from the intestine of a healthy human and has high safety; can alleviate chronic / acute alcoholism, alcoholic intestinal damage or alcoholic liver damage; can accelerate the metabolism of ethanol and / or acetaldehyde, and delay the onset of intoxication; can shorten the sobering-up time; can reduce the mortality caused by drinking alcohol; can reduce the liver index; can lower the level of AST and / or ALT in serum; can alleviate discomfort caused by ethanol and / or acetaldehyde, and mitigate symptoms such as dizziness, headache, nausea and vomiting, and hangover after drinking alcohol; can ameliorate oxidative stress caused by alcohol, and increase the level of GSH in the liver; and also has excellent resistance to gastrointestinal fluid and bile salt, and can adapt to the complex environment within the body.

The present invention relates to the field of medicine and food technology, and relates to a composition for relieving nausea and vomiting, and specifically to a composition obtained by mixing, heating and beating with ginseng and ginger as main raw materials, and its application in the preparation of a drug for relieving / treating nausea and vomiting. In the composition, the mass ratio of ginseng to ginger is 1:10-1:60, and the mass ratio of the mixed raw materials of ginseng and ginger to water is 1:10-1:40. The composition comprises total ginsenosides and total gingerols, wherein the total ginsenoside content is 15-55%, the total gingerol content is 2.5-9%, and the rare ginsenoside content accounts for more than 60% of the total ginsenoside content of total ginseng. The composition is prepared by the following method: mixing ginseng with fresh ginger, soaking in water, mixing and beating at 60-100°C for 30-75min, that is. The composition of the present invention can significantly relieve nausea and vomiting, and can be used to treat nausea and vomiting caused by various reasons.

The invention relates to the technical field of ginger moxibustion, in particular to a portable temperature-controllable ginger moxibustion device for arresting vomiting of tumor patients, which comprises a shell, a tube is fixedly connected to the inner side wall of the shell, a pore plate is fixedly connected to the bottom of the tube, a temperature sensor is mounted on the inner side wall of the tube, and a cover is in threaded connection to the top of the shell. A cylinder is fixedly connected to the bottom of the cover body, and an electric heating rod is mounted at the bottom of the cylinder; the electric heating rod is used for simulating heating power of moxa in traditional ginger-separated moxibustion, controllable heating power is used for exciting drug efficacy of ginger of ginger slices on the pore plate, the synergistic effect mechanism that ginger penetrates through heating power and drug efficacy enters the acupoint is perfectly rescribed, the device is designed according to the core requirement of descending adverse-rising energy and arresting vomiting of tumor patients, the device can accurately act on related acupoints for arresting vomiting, and the effect is achieved. The symptoms of nausea and vomiting caused by chemoradiotherapy and the like are effectively relieved.

The invention discloses a double-agonist polypeptide compound and medical application thereof, and belongs to the field of polypeptide medicine, the amino acid sequence of the GIP-R and GLP-1R double-agonist polypeptide compound is Y-Z-EGTFTSDSI-X2-LDKI-A-Q-Bn-X4-X5-VQWLI-X6-GGPSSG-A-PPPS, and the amino acid at the C terminal is amidated. The GIP-R and GLP-1R dual-excitation polypeptide compound disclosed by the invention has a more remarkable dual-excitation effect on a human glucose-dependent insulinotropic polypeptide (GIP) and a human glucagon-like peptide-1 (GLP-1) receptor, not only has the effects of reducing blood glucose and reducing weight, but also has a longer half-life period and higher bioavailability; adverse reactions such as nausea and vomiting caused by long-term use of existing medicines can be avoided, and the traditional Chinese medicine composition can be used as an effective raw material for preparing medicines for treating or preventing diabetes or weight-reducing medicines.

The invention relates to the field of traditional Chinese medicines, and discloses a traditional Chinese medicine composition for treating postoperative digestive tract reaction of malignant tumors, a preparation and application. The traditional Chinese medicine composition comprises the following active ingredient raw materials in parts by weight: 10-20 parts of fried codonopsis pilosula, 10-20 parts of fried bighead atractylodes rhizome, 10-20 parts of poria cocos, 1-10 parts of liquorice, 10-20 parts of fried endothelium corneum gigeriae galli, 15-25 parts of fried malt, 25-35 parts of adina rubella hance root, 25-35 parts of wild grape root, 15-25 parts of Chinese actinidia root and 15-25 parts of coix seed. The traditional Chinese medicine composition and the preparation can effectively treat patients with malignant tumor postoperative digestive tract reaction, effectively improve symptoms of abdominal distension, stomachache, nausea, vomiting, diarrhea, constipation, anorexia, sour regurgitation, oral cavity / throat dryness and the like of the patients, improve the life quality of the patients and have good safety.

The utility model discloses a tumor patient nausea and vomiting evaluation device, and particularly relates to the technical field of tumor patient nausea and vomiting evaluation, the tumor patient nausea and vomiting evaluation, the tumor patient nausea and vomiting evaluation device comprises a digital scoring ruler and a facial expression scoring ruler, the bottom end of the digital scoring ruler is provided with a cavity adapted to the sliding placement of the facial expression scoring ruler, and the side end of the facial expression scoring ruler is provided with an accommodating groove; and rolling wheels are rotationally mounted in the accommodating grooves and are in rolling fit with the side walls of the cavities. According to the device, the facial expression scoring ruler is arranged in the digital scoring ruler in a sleeving manner, so that the device is convenient for medical staff to carry and also convenient for the medical staff to select an evaluation tool which is most suitable for a patient to use.

Disclosed are the use of methods for reducing one or more gastrointestinal side effects in a subject receiving glucagon-like peptide-1 (GLP-1) receptor agonist (RA) therapy. The methods include administering to a subject receiving GLP-1 RA therapy an amount of homotaurine-like gastrointestinal distress-relieving (HTL-GIDR) composition effective to reduce gastrointestinal side effects of GLP-1 RA therapy, e.g., nausea, vomiting, and constipation. Generally, the HTL-GIDR composition can be homotaurine or a homotaurine analog such as acamprosate calcium and valiltramiprosate (ALZ-801), or a combination thereof. Furthermore, the HTL-GIDR composition may facilitate tolerance during the GLP-1 RA dose escalation phases and enable administration of higher GLP-1 RA doses, thereby enhancing therapeutic outcomes in conditions including diabetes, obesity, and neurodegenerative diseases.

The invention discloses a traditional Chinese medicine composition for treating chemotherapy-related nausea and vomiting, an acupoint patch and a preparation method, and belongs to the technical field of traditional Chinese medicine research. According to a fine-tuning external application formula, acupoint external application is achieved, medicine transdermal absorption is matched with acupoints to stimulate channel and qi combination, and the effect is special and strong; the medication route is changed, oral administration is avoided, and the gastrointestinal burden is relieved. Aromatic traditional Chinese medicines are used for guiding channels, promoting qi circulation, dredging collaterals and promoting transdermal absorption; and the aromatic traditional Chinese medicines enter spleen and stomach channels, enlivene spleen and please stomach, and are helpful for improving gastrointestinal reactions such as nausea and vomiting. The acupoint patch is simple and easy to operate and learn, has a high degree of recognition by the masses, and is easy to popularize in western medicine hospitals and primary hospitals.

The invention discloses a traditional Chinese medicine composition for treating a warm disease clinically belonging to the same disease of defensive qi and a preparation method and application thereof.The traditional Chinese medicine composition is prepared from, by weight, 5-35 parts of bupleurum chinense, 9-50 parts of scutellaria baicalensis, 9-50 parts of artemisia apiacea, 5-35 parts of radix paeoniae rubra, 5-35 parts of moutan bark and 4-26 parts of folia perillae acutae. According to the traditional Chinese medicine composition, the effects of all the medicines are utilized to generate a synergistic effect, and the effects of relieving fever, eliminating evil and detoxifying are achieved together. The traditional Chinese medicine composition is used for treating fever or hyperpyrexia, slight aversion to wind-cold, headache, sweating, thirst, cough and pharyngalgia caused by cold, viral cold and upper respiratory tract infection febrile disease defensive qi, and can be accompanied by nausea, vomiting, neck stiffness, rash appearance, red eye swelling and pain and the like, so that the febrile disease is effectively treated.

The utility model discloses a record board for nausea and vomiting conditions caused by chemotherapy, and relates to the field of medical instruments. The recording board comprises a panel and a marking block, wherein the panel is provided with two condition information areas and two condition recording grooves; the condition information area comprises four condition grading areas; four condition grading areas of one condition information area respectively have nausea grade information, and four condition grading areas of the other condition information area respectively have vomiting grade information; the condition recording grooves and the condition information areas are arranged in a one-to-one correspondence mode, each condition recording groove comprises a lower transverse groove, a communicating vertical groove, four communicating transverse grooves and four recording vertical grooves, the recording vertical grooves and the condition grading areas are arranged in a one-to-one correspondence mode and are close to the condition grading areas, and the communicating vertical grooves are located on the outer sides of the recording vertical grooves; the communicating transverse groove communicates with the upper end of the recording vertical groove and the communicating vertical groove, and the lower transverse groove is located at the lower end of the communicating vertical groove and forms a T-shaped groove together with the communicating vertical groove; and seven marking blocks are placed in each condition recording groove.

A use of a compound of formula (I) or a stereoisomer, hydrate, metabolite, solvate, pharmaceutically acceptable salt and eutectic thereof or a composition thereof in the preparation of a drug for preventing postoperation nausea and vomiting or chemotherapy-induced nausea and vomiting.

The present invention belongs to the field of biotechnology, and specifically relates to a strain of animal Bifidobacterium lactis subsp. lactis BX‑186 that alleviates the adverse effects of semaglutide. The classification name of the animal Bifidobacterium lactis subsp. lactis provided by the present invention is: Bifidobacterium animalis subsp. lactis, the deposit unit is: General Microbiology Center of China Microbiological Culture Collection Administration Committee, the deposit number is: CGMCC No. 27837, and the deposit time is July 7, 2023. The animal Bifidobacterium lactis subsp. BX‑186 provided by the present invention directly interacts with the intestinal flora, thereby affecting the metabolic activities and physiological functions of the intestinal microorganisms, restoring the balance of the intestinal flora, and can alleviate the gastrointestinal discomfort symptoms caused by semaglutide, including nausea, vomiting and diarrhea, etc., and can also reduce body weight and the content of glycosylated hemoglobin HbA1c in the blood, and has broad application prospects.

The invention relates to the field of traditional Chinese medicine formulas, and particularly discloses a traditional Chinese medicine composition for treating stomach illness and a preparation method thereof, and each dose of the traditional Chinese medicine composition is prepared from the following components by mass: 30-50 g of rhizoma bletillae, 30 g of radix cynanchi bungei, 20-30 g of cuttle bone, 20-30 g of pseudo-ginseng, 20 g of rhizoma corydalis and 20 g of radix aucklandiae. A method for preparing the traditional Chinese medicine composition for treating stomach diseases comprises the following steps: step 1, mixing the rhizoma bletillae, the radix cynanchi bungei, the cuttle bone, the pseudo-ginseng, the rhizoma corydalis and the radix aucklandiae in proportion, and crushing twice by adopting a high-speed crusher; the traditional Chinese medicine prepared by the invention has a good treatment effect on stomachache, such as gastric ulcer, duodenal ulcer, chronic gastritis, gastrorrhagia, stomachache, stomachache, dyspepsia and the like; through the synergistic effect of various traditional Chinese medicines, the traditional Chinese medicine composition can effectively relieve clinical symptoms such as stomachache, stomachache, sour regurgitation, nausea and vomiting, and meanwhile, can promote the repair of gastric mucosa and the healing of ulcer surfaces.

The invention relates to the technical field of biological medicine, in particular to a medicine solution composition, a preparation method thereof, a nasal spray and application. The medicine solution composition comprises a medicine active component, an osmotic pressure regulator, a pH regulator and water. The active pharmaceutical ingredient comprises ondansetron or a pharmaceutically acceptable salt of ondansetron. The medicine solution composition provided by the invention can be quickly absorbed into blood through nasal mucosa, reaches a peak within 5-10 minutes after being administered through nasal spray administration, is expected to take effect quickly, can help a patient to deal with nausea and vomiting caused by cytotoxic chemotherapy and radiotherapy in time and be used for preventing postoperative nausea and vomiting (PONV), and is good in stability.

The present invention relates to the technical field of traditional Chinese medicine for treating hypertension vertigo, and particularly relates to a traditional Chinese medicine compound composition for treating hypertension vertigo and a preparation method thereof. Calculated by mass parts, the raw materials of the traditional Chinese medicine compound composition for treating hypertension vertigo include: calcined magnetite 30 - 120 parts, eucommia ulmoides 15 - 60 parts, gastrodia elata 20 - 180 parts, apocynum venetum leaves 15 - 120 parts, cyathula officinalis 10 - 40 parts, pinellia ternata processed with rhizoma zingiberis recens 8 - 30 parts, stir-fried atractylodes macrocephala 15 - 120 parts, alisma orientale 10 - 120 parts, pueraria lobata 30 - 120 parts, corn stigma 10 - 60 parts, and stevia rebaudiana 10 - 40 parts. The traditional Chinese medicine compound composition of the present invention has a good antihypertensive effect on patients with hypertension vertigo, can significantly improve the clinical symptoms of patients with hypertension vertigo such as dizziness and heaviness in the head, dizziness and blurred vision, dimmed vision, tinnitus and bitter taste in the mouth, nausea and vomiting, limb numbness, restlessness and difficulty in falling asleep, etc. The curative effect on treating hypertension vertigo (syndrome of wind-phlegm disturbing upward) is definite, and the medication is safe and reliable.

The invention relates to the technical field of biology, in particular to a hangover alleviating composition containing dendrobium small molecule peptide and a preparation method, the hangover alleviating composition containing dendrobium small molecule peptide mainly comprises dendrobium small molecule peptide extract, the dendrobium small molecule peptide extract contains small molecule peptide DHP-1 (Gly-Ala-Val-His-Leu), DHP-2 (Pro-Tyr-Ser-Met-Gln) or DHP-3 (Asp-Ile-Thr-Lys-Cys) which are not reported, and the hangover alleviating composition further comprises auxiliary materials such as vitamin C, glucose and citric acid. After drinking, the alcohol concentration in blood is obviously lower than that of a person who does not take the alcohol-dispelling beverage within a certain period of time, so that the composition has a good alcohol-dispelling effect. After the anti-alcoholism beverage is taken, drunkenness symptoms such as dizziness, nausea and vomiting are obviously relieved, and the comfort level of a subject is improved. Liver function indexes (such as glutamic-pyruvic transaminase, glutamic oxalacetic transaminase and the like) are detected to find that the liver injury degree of a subject who drinks the anti-alcohol beverage for a long time is obviously lower than that of a single drinker, so that the composition has a protective effect on the liver.

The present application belongs to the technical field of traditional Chinese medicine, and particularly relates to a traditional Chinese medicine composition with an antiemetic effect and a preparation method thereof. The traditional Chinese medicine composition contains perilla leaf, Coptis chinensis, Amomum villosum, Saussurea lappa, Pinellia ternata, ginger, Chinese yam and honey. The traditional Chinese medicine composition has a good relieving and treating effect on pregnancy vomiting through pharmacological experiments and clinical use verification. The clinical treatment rate of pregnancy vomiting reaches 92.86%, and the traditional Chinese medicine composition can effectively relieve the clinical symptoms of patients, such as nausea and vomiting, dizziness, anorexia, food entering the stomach and then vomiting, and the like. The preparation process is simple, the traditional Chinese medicine composition can be further produced, and has a wide market prospect.

This invention provides a method for treating postoperative nausea and vomiting using buccal acupuncture combined with a triple antiemetic regimen. The method employs a combined intervention of buccal acupuncture and a triple antiemetic regimen. The triple regimen consists of a 5-HT3 receptor antagonist, a glucocorticoid, and a dopamine receptor antagonist, administered intravenously in two separate doses. The buccal acupuncture uses CA-2 (upper jiao), CA-3 (middle jiao), and CA-4 (lower jiao) as core acupoints, with auxiliary and reinforcing acupoints added based on the surgical site and high-risk groups. A standardized procedure of pecking stimulation is applied, along with a corresponding postoperative remedial antiemetic medication regimen. This invention organically combines multi-target drug blockade with buccal acupuncture's visceral regulation, synergistically enhancing the antiemetic effect, reducing the incidence of nausea and vomiting, and decreasing the need for remedial medication. The regimen is highly standardized, widely adaptable, and can meet the postoperative nausea and vomiting control needs of various surgeries and high-risk groups. It exhibits good safety, strong repeatability, and high clinical application value.

The invention discloses a Chinese medicine antiemetic mixture for preventing and treating postoperative nausea and vomiting, and a preparation method and application thereof. The Chinese medicine antiemetic mixture comprises the following Chinese medicine ingredients: codonopsis pilosula, pinellia tuber, atractylodes lancea, magnolia officinalis, tangerine peel, clove, roasted liquorice, black dates and dried ginger. The Chinese medicine antiemetic mixture is a pure Chinese medicine preparation, which embodies the characteristics of multi-target and comprehensive synergistic treatment of Chinese medicine, has the effects of strengthening the spleen and stomach, reducing adverse reactions and stopping hiccups, removing dampness and resolving phlegm, and is mainly used to treat spleen deficiency and vomiting. The Chinese medicine antiemetic mixture has a wide range of application, can be widely used to prevent nausea and vomiting, can be promoted and applied to the prevention and treatment of various surgical PONV, vomiting caused by radiotherapy and chemotherapy, alcohol detoxification and vomiting, and motion sickness and seasickness of passengers. It has a significant effect on the treatment of postoperative nausea and vomiting, especially postoperative nausea and vomiting after total knee replacement, has no obvious adverse reactions, can reduce or avoid the frequency of use of other Western medicines, and is worthy of development and clinical promotion.

The present disclosure relates generally to methods of treating, preventing, or reducing nausea, vomiting, or a combination thereof, hyperemesis gravidarum (HG), nausea gravidarum and vomiting (NVP), or sequelae thereof in a human subject in need thereof, the methods comprise administering to the human subject a therapeutically effective amount of an antibody that specifically binds to a human glial cell line derived neurotrophic factor family receptor alpha-like (GFRAL).

This invention belongs to the field of traditional Chinese medicine technology, and relates to a topical Chinese medicine composition, topical drug, topical patch, acupoint patch, and preparation method and application for treating nausea and vomiting caused by chemotherapy for intracranial tumors. The Chinese medicine composition consists of the following raw materials in parts by weight: 1-2 parts of Ligusticum chuanxiong, 1-2 parts of Gastrodia elata, 2-4 parts of Uncaria rhynchophylla, 1-2 parts of Citrus aurantium, 1-2 parts of Sinapis alba, 1-2 parts of Clematis chinensis, 0.5-1 part of Melia toosendan, 0.5-1 part of Panax ginseng, 1-2 parts of Pinellia ternata, 1-2 parts of Albizia julibrissin bark, 0.5-1 part of Lentinus edodes, and 1-2 parts of Astragalus membranaceus. This Chinese medicine composition has the effects of relieving nausea and vomiting, soothing the liver and strengthening the spleen, detoxifying and eliminating turbidity, calming the liver and extinguishing wind, and calming the mind and soothing the nerves. It not only effectively controls the nausea and vomiting symptoms caused by chemotherapy for intracranial tumors, but also harmonizes the body's Qi and organ functions. The Chinese medicine composition has a simple formula, widely available ingredients, and a simple preparation method; it is for topical application, convenient for clinical use, and has low adverse reactions.

The invention provides application of nifurazide or a pharmaceutically acceptable derivative thereof and a pharmaceutical composition, and belongs to the technical field of biological medicines. The application comprises application of nifurazil in preparation of drugs for reducing food intake and / or inhibiting appetite. The nifurazil does not depend on blood sugar regulation and intestines and stomach, and does not cause side effects of nausea and vomiting; the action target of the nifurazil is not located in the peripheral nervous system but acts on the central nervous system, and the nifurazil can be used for remarkably reducing the intake of common food and high-fat food of mice and inhibiting the appetite of the mice in a mode of activating Glp1-r, so that the weight of the obese mice is remarkably reduced. Therefore, the nifurazil has the potential of treating the obesity and can be applied to preparation of the medicine for treating the obesity.

The invention belongs to the technical field of medicine preparation, and particularly relates to a composition for relieving nausea and vomiting symptoms caused by chemotherapy and application of the composition. 38-42 parts of lily, 25-30 parts of black dates, 17-23 parts of herba violae, 15-19 parts of pumpkins, 9-13 parts of fructus gardeniae and 5-10 parts of flaxseeds are specifically combined, all the raw materials can achieve a synergistic effect, gastrointestinal mucosa is protected, irritation of chemotherapeutic drugs to gastrointestinal tracts is reduced, and the occurrence rate of vomiting is reduced; in addition, the raw materials can regulate the immune function of the body, enhance the resistance of the body and relieve the adverse effect of chemotherapeutic drugs on the body, so that vomiting is indirectly relieved. Therefore, the composition provided by the invention can be used for preparing products for relieving nausea and vomiting symptoms caused by chemotherapy, the preparation method is simple and convenient, the vomiting symptoms can be prevented and treated in a targeted manner, and the pain of patients is greatly relieved.

The invention discloses a GLP-1R receptor agonist polypeptide compound and application thereof, and belongs to the field of polypeptide medicines, and the amino acid sequence of the GLP-1R polypeptide compound is H-X1-EGTFTSDVSYLEGQ-X2-X3-Bn-EFI-X4-X5-L-X6-RGRG. The invention further discloses a preparation method of the GLP-1R receptor agonist polypeptide compound. The GLP-1R polypeptide compound disclosed by the invention has a more remarkable agonistic effect on a human glucagon-like peptide-1 (GLP-1) receptor, not only has the effects of reducing blood glucose and reducing weight, but also has a longer half-life period and higher bioavailability, can avoid adverse reactions such as nausea and vomiting caused by long-term use of existing medicines, and has a good application prospect. The compound can be used as an effective raw material for preparing medicines for treating or preventing diabetes or weight-reducing medicines.

The invention discloses anti-vomiting hydrolyzed whey protein and a preparation method thereof, and belongs to the technical field of food processing. The product provided by the invention reduces the digestion burden of protein and relieves the symptom of vomiting. According to the method disclosed by the invention, protein sequences are mutually crosslinked by virtue of a treatment mode of first fibration, second polymerization and final hydrolysis, and a hydrolyzed polypeptide sequence is changed, so that the abundance of the polypeptide SLAMAASDISLA in a hydrolysate is improved. The polypeptide has the characteristics of being easy to recognize by intestinal peptidase and relatively high in PepT1 affinity, the bioavailability of protein is improved, and the deamination proportion of unutilized amino acid is reduced, so that substances generating nitrogen-containing toxoid are reduced, the stimulation of toxin accumulation on gastrointestinal mucosa is relieved, and the symptoms of nausea, vomiting and the like of a user are avoided.