The invention discloses a hypertension injection nursing drug and a preparation method thereof. The drug is a pure traditional Chinese medicine formula and is mainly made from the following Chinese medicinal herbs: radix paeoniae alba, wolfberry fruit, radix rehmanniae, Chinese yam, pubescent holly root, corn stigma, keel, oyster, nepenthe, botrychium daucifoltum woll, poria, bighead atractylodes rhizome, licorice, euryale ferox, radix rehmanniae, rhizoma phragmitis, gastrodia elata, earthworm, radix angelicae, twig, rhizoma corydalis, lysimachia, bamboo leaf, rhubarb, lamp wick, isatis root, hawthorn, eucommia, bidens bipinnata, leech, apocynum, royal jelly, rhizoma chuanxiong, coptidis, angelica, parasitic loranthus, radix paeoniae rubra, radix achyranthis bidentatae, radix puerariae, astragalus root, tortoise shell, cortex lycii radicis, selfheal, chrysanthemum, semen brassicae and cortex moutan. The hypertension injection nursing drug has the advantages of being significant in curative effect and free of side effect.