75 results about "Hyperviscosity" patented technology

The present invention is related to a pharmaceutical composition comprising snail slime of Helix aspersa müller (Cryptophalus aspersus) (5% to 50%) and marigold extract, propolis and/or almond oil and pharmacologically accepted additives for the prevention additives and/or pharmaceutically acceptable excipients to form a formulation of intermediate to high viscosity (200 to 1000 Pa-s). This invention also relates to the use of a composition which can be formed as a cream or a gel, is preferably soaked in gauze, and shaped as a bandage or sock for the treatment and cure of diabetic foot ulcers and other severe wounds, particularly those associated with diabetes, gout, Lesch Nyhan syndrome or other conditions to the skin, including, keratosis, onychomycosis, ringworm, among others.

Preparation and application methods of micromolecular water are disclosed. According to the invention, water which reaches drinking standard is heated and boiled in a pulse concussion electric field; and under the condition of low pressure, the water is rapidly cooled to room temperature within 30 minutes and filling is carried out. The preparation method is simple and convenient to regulation and control. Magnetic micromolecular water has good health care effects of treating heart and brain atherosclerosis, hypertension, hyperlipidemia and hyperviscosity, and provides important supports for technical progress of health and fitness.

A health-care bag tea for relaxing hypertension, hyperlepemia, hyperglycemia and hyperviscosity, nourishing liver and kidney, preventing cancer and delaying senility is prepared from 6 Chinese-medicinal materials including red sage root, haw, fleece flower root, astragalus root, etc.

Processes and devices are disclosed for parenteral delivery of therapeutic fluids, in particular high-viscosity therapeutic fluids (e.g., protein therapeutics), by a chemical reaction that generates a gas. The device may include a first actuation chamber containing a first reagent, a second reaction chamber containing a second reagent, and a third therapeutic fluid chamber containing the therapeutic fluid. In a loaded configuration, a plunger separates the first chamber from the second chamber. In a delivery configuration, the plunger allows the first reagent from the first chamber to communicate and react with the second reagent from the second chamber. The generated gas acts upon a plunger to deliver the therapeutic fluid from the third chamber.

The invention provides a waterborne polyurethane emulsion with flexural endurance and a preparation method thereof. The emulsion comprises water and resin. The resin contains the following reaction components: aliphatic diisocyanate, aromatic diisocyanate, polyester polyol, polyether polyol, a hydrophilic chain-extender, a short-chain chain extender and a post chain extender. The preparation method comprises the following steps: letting polyether polyol react with aromatic diisocyanate to obtain a component A; letting the component A react with aliphatic diisocyanate and polyester polyol to obtain a component B; adding the hydrophilic chain-extender into the component B and reacting, adding the short-chain chain extender and reacting, cooling to 50 DEG C below, adjusting pH value and viscosity, adding water, and carrying out an emulsion reaction to obtain the waterborne polyurethane emulsion with flexural endurance. By preferentially carrying out a reaction between polyether polyol and aromatic diisocyanate, adverse effects of system hyperviscosity and solidification due to high crystallinity of aromatic diisocyanate are avoided.

A closed-system urinary catheter with a low viscosity gel lubrication is disclosed. The system has an uncoated catheter, but a hydrophilic coated catheter could be used. The low viscosity lubricating gel within the sachet uniformly coats the catheter when the sachet is ruptured just prior to use. A low viscosity lubrication gel could alternatively be place in the area inside the sheath and external to the catheter. Therefore, the variability that occurs with a hydrophilic catheter or the areas of a non-lubricated catheter with the higher viscosity gel catheters is avoided.

The invention discloses health-care nourishing tea capable of relieving blood pressure, blood fat and blood sugar, belonging to the field of health-care nourishing tea products. The health-care nourishing tea is prepared from China Northeast black fungus, China Northeast wild acanthopanax seeds, cassia seeds, China Northeast corn stigma, eucommia, uncaria and apocynum. The health-care nourishing tea is prepared by the steps as follows: drying China Northeast black fungus and China Northeast wild acanthopanax seeds in high temperature; airing cassia seeds, China Northeast corn stigma, eucommia, uncaria and apocynum; and after the above treatment, mixing the materials by weight ratio. The health-care nourishing tea is simple in the preparation technology and utilizes the efficacies of China Northeast black fungus, China Northeast wild acanthopanax seeds, cassia seeds, China Northeast corn stigma, eucommia, uncaria and apocynum as traditional Chinese medicines, thus having excellent curing and regulating effects to groups suffering from hypertension, hyperlipaemia, hyperviscosity, hyperglycemia, arteriosclerosis and heart cerebrovascular diseases; and the health-care nourishing tea is low in cost, infused with boiled water, convenient to drink and suitable to sub-health groups.

The invention relates to a drug for treating hyperlipidemia, hyperviscosity, hypertension and coronary heart diseases, which takes special medicinal materials in the Guangxi zhuang nationality autonomous region as raw materials, and comprises the following components by weight part: 1-3 parts of lysidice rhodostegia hance, 1-4 parts of ginger powder, 1-2 parts of galangal, 1-2 parts of oyster, 0.1-1 part of puerarin powder, 0.1-0.5 part of honeysuckle, 0.1-0.5 part of hawthorn and 0.1-0.5 part of mint. The drug has the characteristics of obvious curative effect, no toxic or side effect, long-term use and no dependence.

The invention discloses a regenerated OGFC (Open-graded Friction Courses) mixed material and a preparation method thereof. The mixed material comprises cellulose, hyperviscosity modified asphalt, new mineral aggregate, mineral powder and an OGFC old material. The preparation method comprises the following steps: respectively heating the OGFC old material, new mineral aggregate and hyperviscosity modified asphalt; then, mixing the heated OGFC old material and the new mineral aggregate with cellulose; then, adding the heated hyperviscosity modified asphalt into the mixture and mixing; then, adding the mineral powder, continuously mixing to form a regenerated OGFC mixed material; and finally, carrying out a Xielunbao asphalt leakage loss experiment and performance index test on the regenerated OGFC mixed material. The preparation method of the regenerated OGFC mixed material provided by the invention is simple to operate and accurate in result, and the potential value of the OGFC old material is fully utilized and the OGFC old material is reduced to the regenerated OGFC mixed material, so that the cost of OGFC is lowered.

The invention discloses a composition of effective parts of ground beetle small peptides for treating cardiovascular diseases and belongs to the field of traditional Chinese medicine. The composition is characterized by being prepared into a corresponding dosage form by extracting effective parts from ground beetle, pseudo-ginseng, radix salviae miltiorrhizae and ramulus uncariae cum uncis and adding pharmaceutical adjuncts according to a specific ratio and conventional methods. The composition as a pure traditional Chinese medicine preparation is capable of treating hypertension, hyperviscosity, coronary disease and angina pectoris effectively and is low in raw material cost and exact in treatment effect, thereby being promising in application prospect.

The invention discloses a Chinese herbal medicinal composition used for reducing blood viscosity and blood lipid. The Chinese herbal medicinal composition used for reducing blood viscosity and blood lipid mainly comprises the following raw materials in parts by weight: 10-60 parts of milk vetch, 5-30 parts of szechuan lovage rhizome, 3-18 parts of earthworm, 1.5-9 parts of leech, 10-30 parts of rhizome alismatis, 10-30 parts of hawthorn, 10-35 parts of salviae miltiorrhizae, 15-30 parts of herba siegesbeckiae, 10-30 parts of semen cassiae, 5-30 parts of seaweed and 5-30 parts of liquorice. Clinical results and experiments show that the Chinese herbal medicinal composition disclosed by the invention has the effects of tonifying qi, strengthening the body resistance, invigorating blood circulation to dredge vessels, reducing phlegm and discharging dirt, hemorheology of middle-aged patients can be improved, blood lipid can be regulated, occurrence and development of atherosclerosis can be prevented and delayed, blood supply and oxygen supply of important organs such as the heart and the brain can be improved, and the Chinese herbal medicinal composition disclosed by the invention is mainly used for treating hyperviscosity and hyperlipoidemia and can be used for preventing apoplexy diseases and heart diseases such as cerebral infarction, angina, cerebral ischemia, ischemia apoplexy and myocardial infarction.

The invention discloses a Hippophae rhamnoides composition with effect of anti-coagulation, anti-platelet aggregation and anti-thrombus, and a preparation method thereof, and belongs to the field of preparation of dietary therapy products, health care products and drugs with State Drug Administration approval numbers, wherein the composition with medical and edible dual-purpose comprises, by weight, 20-45 parts of a Hippophae rhamnoides seed proanthocyanidin extract, 20-40 parts of an Allium macrostemon Bunge extract, and 20-45 parts of a fried Perilla seed extract. The preparation method comprises: extracting at a temperature (less than 50 DEG C), concentrating at a low temperature (less than 50 DEG C), and drying at a low temperature (less than 50 DEG C) so as to retain the biologicallyactive ingredients at a maximum. According to the present invention, the composition is made from the materials with medical and edible dual-purpose, such that the product is safe and can be taken fora long time; and the product can provide effects of anti-coagulation, anti-platelet aggregation and anti-thrombus, and is the safe and effective product for people with abnormal blood fat, abnormal blood viscosity, hyperlipidemia and hyperviscosity, and middle-aged and elderly people in the prevention of the occurrence of cardiovascular and cerebrovascular diseases and the prevention of the aggravation of cardiovascular and cerebrovascular diseases.

A dispersing tablet of Xindakang with high solubility and disintegrating speed for treating ischemic heart disease, arrhythmia, hypertension, hyperlipemia, hyperviscosity blood, etc is prepared from flavone acetylsalicylate and proper additive. Its preparing process is also disclosed.

The invention relates to a medicament for treating or preventing coronary disease, angor pectoris, myocardial infarction, arrhythmia, ischemic brain disease, cerebral thrombosis, cerebral hemorrhage and sequelae thereof, vascular dementia and peripheral circulation disturbance disease, including various artery occlusions, vasculitis, and microcirculatory disturbance caused by diabetes mellitus, high blood pressure, hyperlipidemia and hyperviscosity as well as refractory neck syndrome, vertebrobasilar artery insufficiency and other ischemic diseases accompanying with microcirculatory disturbance, namely, a scutellarin derivative and preparation and application thereof. The derivative has high storing stability, and is suitable for preparing a medicament for treating or preventing heart cerebrovascular diseases.

The invention discloses a preparation process and device of a seven-leech language-resolving pill in the technical field of language-resolving pills. The preparation process comprises the following steps that 1, required medicinal materials are grabbed for later use; 2, 9g of scorpion, 9g of centipede and 15g of earthworm prepared in the step 1 are soaked with yellow wine, and baking on fire is achieved for later use; 3, the core of 9g of the prepared polygala tenuifolia in the step 1 is removed; and 4, 30g of the prepared herba siegesbeckiae in the step 1 is steamed and dried by using a steamer for nine times, and drying in the sun is achieved for later use. According to the preparation process and device of the seven-leech language-resolving pill, the seven-leech language-resolving pill has the effects of promoting blood circulation to remove blood stasis, removing blood stasis, discharging pollution, resisting coagulation and inflammation, reducing blood viscosity, promoting blood circulation and eliminating swelling and the blood stasis; the blood fat and blood viscosity can be reduced, toxic substances in blood can be rapidly removed, hyperviscosity caused by hyperlipidemia and hyperglycemia can be reduced, vascular resistance can be relieved, and vascular elasticity can be recovered.

The invention discloses a lung benefiting pill with 25 ingredients having the function of being homology of medicine and food. The composition of the lung benefiting pill comprises sea buckthorn, radix pseudostellariae, polyporus umbellatus, platycodon grandiflorum, stir-baked rhizoma dioscoreae, milk steamed poria cocos, longan aril, north astragalus, baked perilla seed, baked semen raphani, baked semen brassicae, radix glehniae, radix salviae miltiorrhizae, spina date seed, gecko tails, cordyceps sinensis, almonds, fructus schisandrae, linden honey, salted alisma orientalis, atractylodes macrocephala koidz baked with bran, angelica sinensis, milk steamed polygonatum kingianum, radix ophiopogonis, raw lily and the like. The lung benefiting pill is advantageous to guarantee normal ventilation of alveolus pulmonis and relieves organism anaerobic condition. Due to the fact that the permeability of lung blood capillary is improved, gas exchange is facilitated, and the symptoms of dyspnea and coughing with expectoration are relieved. Weak people with dyspnea and chronic cough generally has the abnormal phenomenon of hemorheology, synchronic treating of phlegm and blood stasis can solve the root cause of sputum and the root cause of blood stasis, bronchospasm can be relieved, discharging of sputum is promoted, cohesive force of red blood cells can be relieved, the blood viscosity is lowered, the hyperviscosity of the weak patients with dyspnea and chronic cough can be relieved, the cardio-pulmonary function of the patients can be improved, and therefore, the lung benefiting pill has good effect on treatment of the patients of this kind.

The invention aims to disclose new application of inulin, in particular new application of the inulin in the preparation of medicaments and health-care products for preventing and treating hyperur icemia. The hyperur icemia also comprises high uric acid merged hypertriglyceridemia, high uric acid merged hyperglycemia, high uric acid merged hypertriglyceridemia and hyperglycemia, high uric acid merged hypercoagulable and/or hyperviscosity, and the like. When used for preventing and treating the symptoms, the inulin has high safety and no adverse reaction or toxic and side reactions.

The invention discloses health-care cigarettes, which comprise, in the proportion by weight, 1-106 parts of tobacco shreds or filters for making cigarettes, and 1-100 parts of lumbrukinase. Soluble health-care products, preferably the lumbrukinase, are sprayed to the tobacco shreds or filters of the cigarettes to be made, and accordingly a smoker smoking the cigarette can inhale the smoke with the lumbrukinase. According to the latest researches, the lumbrukinase not only can activate fibrinoclase to dissolve thrombus, but also can directly dissolve fibrous proteins. The effective rate of the lumbrukinase in clinical treatment of thrombus reaches more than 80%, and the lumbrukinase is further capable of reducing blood viscosity, inhibiting platelet aggregation, resisting blood coagulation, promoting blood circulation and the like, and has therapeutic effects on apoplexy sequela, arteriosclerosis, hypertension, hyperviscosity and the like.

The invention relates to a medicine for treating hypertension, hyperlipoidemia and hyperviscosity. The medicine is prepared from the following traditional Chinese medicines by weight percent: 9-12% ofangelica, 9-12% of rehmannia root, 9-12% of red peony root, 0.2-0.9% of leech, 5-10% of radix bupleuri, 10-12% of semen raphani, 9-12% of rhizoma atractylodis, 9-12% of tuckahoe, 10-15% of hawthorn,9-12% of twotooth achyranthes root, 5-9% of rhizoma ligustici wallichii, 3-5% of radix platycodi and 3-5% of licorice. By adopting the medicine provided by the invention and matching with an acupuncture moxibustion technique, the cost for treating the hypertension, the hyperlipoidemia and the hyperviscosity can be reduced, complications do not exist, the pain of a patient is lightened, and the disability rate and the incidence rate are also lowered greatly.

The invention relates to a method for confirming the gas content in high-viscosity liquid, which comprises the following steps of: detecting and recording the pressure change value of the high-viscosity liquid in a cavity before and after the movement of a guide rod through a pressure sensor, and detecting and recording the density change value corresponding to the high-viscosity liquid flowing out of an output port when the pressure change value is detected and recorded by a densimeter; establishing a pressure and density function relation model by using the pressure and density change values, and generating a functional expression in which the X axis is pressure and the Y axis is density y=bx+c; and calculating and recording a gas content change value by adopting the density change difference value, establishing a pressure and gas content function relation model by utilizing the pressure and gas content change value, and generating a functional expression y=bx+c, in which the X axis is the pressure and the Y axis is the gas content. According to the invention, the pressure change value of the high-viscosity liquid in the cavity before and after the movement of the guide rod detected by the pressure sensor is used as an electric signal to calibrate the gas content in the cavity, and the relative content of the gas in the high-viscosity liquid in the cavity is indirectly detected by combining the programmable technology of the control device.

The present invention relates to the diagnosis of the risk of experiencing a cardiovascular complication in the context of treatment with erythropoiesis stimulating agents (ESA's) such as erythropoietin and derivatives thereof particularly in the context of anemia. More particularly, the invention provides a method for diagnosing the risk of a patient of experiencing a cardiovascular complication as a consequence of future medication with an erythropoiesis stimulating agent (ESA), comprising the steps of (a) measuring the level of a BNP-type peptide in a sample of the patient, (b) diagnosing said risk by comparing the measured level of the BNP-type peptide to at least one reference level. The BNP-type peptide may for example be brain natriuretic peptide (BNP) or the N-terminal fragment of BNP, NT-proBNP. The cardiovascular complication may include complications, such as stroke, transient cerebral ischemic attack, acute-coronary syndrome, myocardial infarction, congestive heart failure etc. Notably, the present invention also relates to dosages of ESA medication which do not cause hyperviscosity.

The invention discloses a traditional Chinese medicine composition for treating hypertension, hyperlipidemia and hyperviscosity, wherein the traditional Chinese medicine composition is prepared from radix puerariae, radix astragali, hawthorn, cassia seed, prunella spike, stir-fried eucommia ulmoides, loranthus parasiticus, radix scutellariae, coptis chinensis, lotus nut, radix aconiti lateralis preparata, herba ephedra, asarum sieboldii, cassia twig, dried ginger, radix saposhnikoviae, full scorpion, centipede, herba cistanche, radix salviae miltiorrhizae, tuber fleeceflower stem, rhizoma atractylodis, rheum officinale, rhizoma cyperi, ligusticum wallichii, medicated leaven, stir-fried cape jasmine, golden cypress, liquorice, rhizoma anemarrhenae, white atractylodes rhizome, rhizoma alismatis and other raw materials, has the functions of promoting yang and relieving diarrhea, invigorating qi for strengthening superficies, activating blood circulation and removing stasis, clearing awayheat and toxic materials, warming spleen and stomach for dispelling cold, activating meridians to stop pain, drying dampness and strengthening spleen, clearing away heat and calming liver and the like, and effectively treats hypertension, hyperlipidemia, hyperviscosity, concurrence of two or three of hypertension, hyperlipidemia and hyperviscosity and other symptoms. The traditional Chinese medicine composition can be made into a variety of preparations, is convenient to take and carry, scientific and rational in formula, small in side effects, simple in preparation method and low in preparation cost, can greatly alleviate the body and economic burden of patients, and has great promotion value.

The invention discloses a Mongolian medicine composition for treating diabetes mellitus, hyperlipidemia and primary hyperviscosity. The Mongolian medicine composition comprises inula, fructus gardeniae, radix platycodonis, rhizoma coptidis and lignum sappan. The Mongolian medicine composition has the advantages that good curative effects can be realized by the Mongolian medicine composition; the obvious curative effects can be realized by the Mongolian medicine composition for corresponding symptoms, the Mongolian medicine composition can become effective fast and is free of toxic and side effects, and the like.

The invention relates to a pharmaceutical composition. The pharmaceutical composition comprises a pharmaceutically active ingredient, glycerol, a sustained release carrier and a pharmaceutically acceptable solvent, wherein the pharmaceutical composition is small in irritation, has good slow release performance, medication safety and tolerance, is a high-viscosity liquid at normal temperature, and is particularly beneficial to perfusion therapy.

The invention relates to a boron dipyrromethene fluorescent probe and a preparation method and application thereof in viscosity detection, and in particular relates to a method for measuring intracellular viscosity by using a fluorescent molecular probe based on a boron dipyrromethene structure. The fluorescence of the fluorescent probe is very weak in a low-viscosity system, the fluorescence of the fluorescent probe is enhanced in a high-viscosity solvent system such as glycerol, and meanwhile, a certain degree of emission spectrum red shift phenomenon is accompanied; therefore, the probe canbe used for detecting the viscosity in different solvent systems; and meanwhile, the probe has good biocompatibility and low toxicity, can be used for detecting viscosity change in cells, and has specific positioning performance on mitochondria.

The invention discloses a Longlifu capsule for preventing and treating fatigue syndrome and a preparation method thereof. The Longlifu capsule contains algae, moss, fungi or plants or derivatives thereof and belongs to the technical field of traditional Chinese herbal preparations containing undefined structures. The Longlifu capsule is composed of 180g of pseudo-ginseng, 90g of American ginseng,9g of cordyceps sinensis and 90g of gynostemma pentaphyllum. The preparation method comprises pulverizing pseudo-ginseng, cordyceps sinensis and American ginseng to obtain coarse powder, uniformly mixing the four types of the coarse powder, grinding the mixture into fine powder, carrying out homogenization, drying, sterilization and screening, and putting the powder into hollow capsules to obtain1000 capsules. The Longlifu capsule has effects of promoting blood circulation to remove blood stasis, strengthening body, resisting fatigue and preventing premature aging. The Longlifu capsule can prevent fatigue syndrome, a sub-health state, hyperlipidemia, hyperviscosity, arteriosclerosis, fatigue syndrome, fatty liver and premature aging and has no toxic or side effect.