The invention provides a river crab hepatopancreatic
necrosis syndrome model, a construction method and application, and belongs to the technical field of
aquaculture. According to the invention,
aflatoxin B1 (AFB1) is utilized to construct a river crab hepatopancreatic
necrosis syndrome model, and river crabs treated by the AFB1 have
pathological characteristics such as severe hepatopancreatic
atrophy,
erosion,
necrosis, color lightening, hepatopancreatic index reduction,
body cavity effusion and the like, and are highly matched with typical symptoms of the river crab hepatopancreatic necrosis syndrome (commonly known as'
Shrimp disease '). According to the river crab hepatopancreatic necrosis syndrome model, the blank of
risk assessment of the river crab hepatopancreatic necrosis syndrome is filled, and theoretical support can be provided for multi-etiological
mechanism analysis and early diagnosis marker screening of the river crab hepatopancreatic necrosis syndrome; a standard
reference model is provided for development of drugs for preventing or treating the hepatopancreatic necrosis syndrome of the river crabs, and the method has important application value for promoting healthy culture of aquatic products.