100 results about "Urinary bladder" patented technology

This utility model relates to the field of urine collection bag technology and discloses a urine collection bag for bladder irrigation in urological patients. It includes a lifting arm and a urine collection bag. A hook is fixedly connected to the middle of the upper surface of the lifting arm, and a warning light is installed in the middle of one side of the lifting arm. A power supply is installed inside the lifting arm. Slides are formed on both sides of the lifting arm. A conductive block is fixedly connected to one side of the bottom wall of the slide, and a spring is fixedly connected to the other side of the bottom wall of the slide. An inlet pipe is fixedly connected to one side of the upper surface of the urine collection bag, and a drain pipe is fixedly connected to the middle of the lower surface of the urine collection bag. This urine collection bag for bladder irrigation, through the design of an observation window and built-in scale lines, reduces the interference of bag deformation and light refraction on readings. Nursing staff can intuitively and accurately read the volume of irrigation waste fluid, ensuring accurate recording of intake and output balance, and providing reliable data support for assessing the patient's bladder irrigation effect, bleeding, and renal function recovery.

The utility model relates to medical instrument technical field especially urine bag suspension protection device with height condition function, the utility model discloses a fixed subassembly, urine bag protection subassembly and be located between the rotating subassembly of fixed subassembly and urine bag protection subassembly, urine bag protection subassembly includes protection bag body, the inside fixedly established inside surface of protection bag body and the outer end passes over the upper portion of protection bag body and is detachably connected with the outside surface of protection bag body cover, the upper portion cover is covered in the outside of cover and the lower portion both ends are fixedly connected with the both side surface of protection bag body mounting bracket and the counterweight fixedly established in the bottom of protection bag body, rotating subassembly includes the fixed seat fixedly established in one side of fixed subassembly, the hook fixedly established in the inside surface upper portion of mounting bracket and with the rotating connection of fixed seat outside surface and with the hook plug -in cooperation rotating mounting seat. The device can keep the urine outlet end of urine bag below the bladder position of patient as far as possible when the body position of patient changes, to avoid the reflux of urine.

The present disclosure provides a balloon-free, self-retainable and threadable urethral catheter that contains special external markings to guide insertion, and that could be indwelled easily and safely. Through various experiments and the structural configuration, the balloon-free, self-retainable and threadable urethral catheter of the present disclosure can make insertion of a mushroom-tip urethral catheter easily performed by primary care medical professionals, instead of previously only been done by senior urologists with a semi-rigid stainless-steel stylet. This disclosure leads to better urine drainage and reduces irritation to the posterior wall of the bladder. With the special design of this disclosure, minor urethral structure can be overcome to insert this catheter safely.

The present invention provides methods for treatment of high-risk non-muscle invasive bladder cancer that is unresponsive to BCG therapy by locally administering gemcitabine to the bladder. Also provided herein are kits and articles of manufacture for treating high-risk non-muscle invasive bladder cancer that is unresponsive to BCG.

The utility model relates to a kind of self-urination metal catheter, it includes the catheter body woven by metal wire, the distal end of catheter body is provided with bending anti-off structure to prevent the distal end of catheter body from being outwardly off from bladder in indwelling state, the proximal end of catheter body is close to external sphincter after passing through prostate area, the proximal end of catheter body is connected with fixed anchor placed in urethra by connecting line, fixed anchor is located at the outside of external sphincter and cannot slide to prostate area inwardly by the block of external sphincter, one end of fixed anchor is connected with traction rope, the other end of traction rope is stretched to patient's outside through urethra.The advantages are that new structure and material are used, infection risk can be effectively reduced, catheter indwelling time is prolonged, and stimulation to urethra or other urinary tissues is reduced;Catheter indwelling period does not need to use urine bag, and patient can self-control urination, improve life quality;Catheter body woven by metal wire is moderately soft and hard, and has good self-adaptability.

This invention provides a pelvic floor support structure model and modeling method based on three-dimensional data to assist in judging the condition of pelvic floor ligaments and to perform physical simulation. To solve the above-mentioned technical problems, this invention provides the following technical solution, including: a bone structure, which includes the hip bone and the coccyx, which together form a pelvic support structure, with the inner side of the hip bone and the coccyx forming the pelvic space; an organ structure, which includes the following model structures, including models of the uterus, bladder, vagina, and rectum located in the pelvic space; and a ligament structure, which includes the cardinal uterine ligament connecting the uterus to the hip bone, the uterosacral ligament connecting the uterus to the coccyx, and the round uterine ligament, which connects one end to the upper end of the uterus and extends obliquely upward at the other end.

In order to confirm the activity state of the pelvic floor muscle in practice of the pelvic floor muscle exercise, a sensor sheet is attached to the abdominal region corresponding to the transversus abdominis muscle, and an electromyogram of the transversus abdominis muscle which contracts in cooperation with the pelvic floor muscle is acquired. At this time, even if the transversus abdominis muscle contracts, the pelvic floor muscle does not necessarily contract, and thus the activity state of the pelvic floor muscle is confirmed by echo. In more detail, an ultrasonic sensor is pressed against the abdomen in a manner that an ultrasonic probe is placed on the sensor sheet, and thus an image (M-mode image) of an ultrasonic echo representing the activity state of the bladder bottom which can be considered to be the same as the contraction of the pelvic floor muscle is acquired. Thereby, the implementer of the pelvic floor muscle exercise can experience the knack of contracting the pelvic floor muscle, that is, what kind of consciousness to focus on which part of the body can contract the pelvic floor muscle.

The application provides a ureteral stent with adaptive high radial support force, which comprises a ureteral segment, a renal pelvis end segment and a bladder end segment connected to two ends of the ureteral segment, and drainage holes are arranged on the side surfaces of the renal pelvis end segment and the bladder end segment; the renal pelvis end segment and the bladder end segment are curved segments, and the ureteral segment is a straight segment; the ureteral segment comprises an inner cladding layer, an intermediate adaptive support layer and an outer cladding layer, the inner cladding layer and the outer cladding layer are respectively arranged on the inner and outer sides of the intermediate adaptive support layer, the inner cladding layer is connected to the inner side of the renal pelvis end segment and the bladder end segment in a smooth transition mode, and the outer cladding layer is connected to the outer side of the renal pelvis end segment and the bladder end segment in a smooth transition mode; the intermediate adaptive support layer comprises a plurality of support members, and the plurality of support members are distributed along the axial direction and the circumferential direction of the ureteral segment.

This invention belongs to the field of medical device technology and provides a constant-temperature warming device for bladder irrigation fluid. The invention includes: a centralized constant-temperature storage tank for centralized preheating and constant-temperature storage of at least one bag of irrigation fluid; and at least one bedside rechargeable tubing temperature monitoring device, which is clamped to the outer wall of the bladder irrigation tubing at the bedside to perform secondary heating or temperature maintenance of the irrigation fluid flowing within the tubing. In summary, this device, through the coordinated operation of the "centralized constant-temperature storage tank" and the "bedside rechargeable tubing temperature monitoring device," coupled with a convenient charging and storage structure and a three-dimensional positioning component, effectively solves the defects existing in the prior art. This solution has a reasonable structural design, high functional integration, and simple operation process, which not only improves the efficiency and safety of nursing work but also provides patients with a more comfortable treatment experience, demonstrating good clinical application prospects and promotional value.

The application relates to the field of urological instruments, and discloses a urinary catheter with a fixing assembly, which comprises a sleeve plate and a catheter body, a receiving structure is arranged on the right side of the upper surface of the sleeve plate, guide pipe structures are arranged on the left and right sides of the upper surface of the sleeve plate, a clamping structure is arranged at the left position of the upper surface of the sleeve plate, and binding structures are arranged on the front and back sides of the sleeve plate. The receiving structure can be used for receiving the excess catheter on the sleeve plate, so that the problem of the catheter being too long is avoided. The clamping structure can be used for clamping a certain position of the catheter on the sleeve plate. The length of the catheter received by the receiving structure can be adjusted through first adjustment, so that the length of the catheter between the clamping structure and the bladder of a patient is adjusted, the problem of the catheter falling off is reduced, the comfort is improved, and the medical work efficiency is improved.

The invention provides devices, systems and methods for tissue approximation and repair at treatment sites. The devices, systems and methods of the invention will find use in a variety of therapeutic procedures, including endovascular, minimally-invasive, and open surgical procedures, and can be used in various anatomical regions, including the abdomen, thorax, cardiovascular system, heart, intestinal tract, stomach, urinary tract, bladder, lung, and other organs, vessels, and tissues. The invention is particularly useful in those procedures requiring minimally-invasive or endovascular access to remote tissue locations, where the instruments utilized must negotiate long, narrow, and tortuous pathways to the treatment site. In addition, many of the devices and systems of the invention are adapted to be reversible and removable from the patient at any point without interference with or trauma to internal tissues.

Provided herein are methods of treatment, erdafitinib for use and use of erdafitinib for the treatment of bladder cancer harboring one or more FGFR alterations comprising locally delivering erdafitinib into the bladder of a patient.

Devices and systems are disclosed for managing and / or treating body tissues obstructing a hollow body lumen, including the prostatic lobe tissues obstructing the urethra, for example conditions including benign prostatic hyperplasia (BPH), bladder outlet obstruction (BOO), benign prostatic obstruction (BPO) and associated lower urinary tract symptoms (LUTS). An implant is maintained in a constrained configuration within a distal portion of an elongated sheath so that is may be deployed by driving the implant with a pusher coaxially disposed within the sheath. An implant engaging element helps maintain control of the implant during deployment.

The application provides a catheterization device for irrigation administration, and relates to the field of medical devices, comprising a catheter and a liquid storage bag, the liquid storage bag is sleeved outside the catheter and is attached to the side wall of the catheter, a through hole connected to the inner cavity of the liquid storage bag is arranged on the side wall of the catheter, a blocking diaphragm capable of being broken under the action of a set pressure is arranged in the through hole, and a blocking piece is arranged in the inside of the catheter in the covering area of the liquid storage bag to block the catheter under the action of the pressure of the side wall of the catheter. In view of the problem that pollution is easily caused during the current bladder irrigation, the flushing liquid is pre-stored in the liquid storage bag, so that the liquid storage bag becomes a convenient flushing device. The flushing liquid is isolated from the outside world before flushing, so that pollution is avoided. When in use, the liquid storage bag is squeezed to make the flushing liquid pass through the through hole and be input along the catheter, so that the operation is convenient and secondary infection is avoided.

The application discloses an ultrasonic imaging system for accurately collecting heart sections in any body position, which comprises a plurality of two-dimensional ultrasonic arrays randomly distributed in space, a multichannel ultrasonic signal collecting module and a three-dimensional ultrasonic imaging module; the plurality of two-dimensional ultrasonic arrays, the multichannel ultrasonic signal collecting module and the three-dimensional ultrasonic imaging module are sequentially connected; wherein the plurality of two-dimensional ultrasonic arrays comprises a plurality of ultrasonic transducer arrays forming sub-area line scanning or sub-area surface scanning or cross surface scanning; the application provides doctors with more detailed images, which is helpful for more accurately positioning and evaluating lesions; can solve the problems of difficulty in collecting correct imaging sections, imaging section changes in motion and the like in wearable ultrasonic heart imaging; is not only suitable for the heart, but also suitable for the brain, the liver, the kidney, the urinary bladder, the abdominal aorta, the inferior vena cava and the like human tissues and parts.

The utility model relates to a cystoscope with bladder support structure's cystoscope, including cystoscope plug pole, the inside of cystoscope plug pole is equipped with the inner cover, the inner side swing joint of inner cover has the inner tube, the inside of inner tube is equipped with the camera, the inside of inner tube is equipped with the electric cautery, the one end of cystoscope plug pole equidistance is opened with fixed recess and first clamping groove, the inside swing of inner cover is equipped with the movable pull rope, the one end fixed connection of movable pull rope is away from cystoscope plug pole has the connection end block, through the mutual cooperation between the movable pull rope, the connection end block and the connection support open mechanism that is equipped with, can when inserting the inside of whole bladder, pull movable pull rope, drive connection end block to remove to be able to cause the pull of connection support open mechanism to the adjustment of connection support open mechanism can be carried out to the movable pull rope, and the movable pull rope is pulled to the inside of whole bladder, drives connection end block to remove, thereby can cause the pull of connection support open mechanism to the adjustment of connection support open mechanism can be carried on, makes connection support open mechanism can prop up the bladder, and the operation is convenient.

The application provides a catheterization device with an adjusting function, comprising: a catheter, one end of the catheter is provided with a catheter head for guiding urine into the catheter head, and the other end of the catheter is provided with an adjusting switch body for adjusting the rate and on-off of the urine discharged from the other end of the catheter; a balloon, the balloon is arranged on the outer peripheral wall of the catheter close to the catheter head, and the balloon can be filled with a medium to fix the catheter in the bladder of a human patient; two electrodes with opposite polarities, one end of each of the two electrodes penetrates through the catheter and extends into the catheter head along the length direction of the catheter, and the two electrodes are respectively used for connecting the positive electrode and the negative electrode of an electrophysiological monitoring device at the end outside the catheter; wherein the catheter, the catheter head and the balloon are all made of an electrically charged silicone rubber material. The application accelerates the recovery of the self-urination ability of the patient and reduces the risk of urinary tract infection of the patient through the adjustment of the adjusting switch body and the electrodes.

A urinary system calculus journey explanation model effectively solves the problem of inconvenient use of existing urinary system calculus journey explanation devices; including a support plate, the left and right sides of the front end of the support plate are respectively provided with a renal pelvis model, the front end of the support plate is provided with a bladder model located below the two renal pelvis models, the left and right sides of the front end of the support plate are respectively provided with ureter models located between the renal pelvis models and the bladder model, the upper end of the ureter model is communicated with the corresponding side of the renal pelvis model and the lower end is communicated with the bladder model, the lower end of the bladder model is communicated with a urethra model, a Y-shaped moving groove is opened on the support plate, the renal pelvis model, the ureter model, the bladder model and the urethra model are provided with a communication groove communicated with the moving groove, the left and right sides of the moving groove are respectively provided with front and rear axial sliding columns, and the front end of the sliding column is detachably connected with a calculus model; this structure is simple, novel in design, convenient to use and high in practicality.

This invention relates to the field of ureteroscopic surgery technology, providing a disposable flexible cystoscopic, pyelonephric, and ureteroscopic system with intelligent temperature and pressure control functions. The system includes a disposable flexible endoscope body and an intelligent temperature and pressure control unit. The disposable flexible endoscope body includes a mid-section flexible insertion tube, a distal sensing lens tip, and a proximal operating handle. The distal sensing lens tip integrates an in-situ temperature and pressure measurement sensor, a miniature imaging module, an illumination fiber optic bundle, an instrument operating channel outlet, an irrigation channel outlet, and a suction channel outlet. Precise real-time monitoring is achieved through the in-situ temperature and pressure sensor at the tip, combined with dual-channel closed-loop control, keeping renal pelvic pressure fluctuations and temperature errors within a safe range, thus reducing the risk of infection and thermal damage at the source. The integrated structure eliminates the need for a pressure measuring sheath, resulting in less trauma and lower cost. Furthermore, the fully automated control significantly shortens the learning curve, greatly improving safety and practicality.

This invention discloses a biomarker, reagent kit, and system for diagnosing bladder injury secondary to benign prostatic hyperplasia (BPH), relating to the field of biomedical detection technology. The biomarker for diagnosing bladder injury secondary to BPH is characterized in that it includes urinary DAB2 protein. This invention achieves (1) clinical applicability: accurate quantitative assessment of the degree of injury. The most significant clinical value of urinary DAB2 protein lies in its ability to transform traditional subjective bladder injury assessment into an objective quantitative indicator. (2) convenient detection: non-invasive and rapid assessment using urine samples. As a urine detection biomarker, urinary DAB2 protein completely changes the traditional bladder injury assessment's reliance on invasive or expensive examinations such as cystoscopy and CT. (3) clinical decision support: the grading diagnostic value of urinary DAB2 protein is directly translated into clinical decision support capabilities, helping to avoid the clinical dilemma of "overtreatment" or "undertreatment."

The invention provides a method of diagnosing overactive bladder disorder (OAB), the method comprising: measuring the concentrations of one or more of adenosine triphosphate (ATP), acetylcholine (ACh), nitric oxide (NO) and interleukin 5 (IL-5) in a sample obtained from a subject; normalising the concentrations to the concentration of creatinine (Cr) in the sample; range standardising the normalised concentrations and subject's age to the following values: Age to 120 years old; ATP / Cr to 0.000001; ACh / Cr to 0.1; NO to 20000; IL-5 / Cr to 100; wherein the likelihood of having OAB (pOAB)=1 / 1+e−x, where X=one or more of the following: (a) (−2.688±1.050)+5.472±2.098×subject's age+1.356±0.559×Gender (Female=1, Male=0)+(−7.998±40.273)×[IL-5 / Cr]; (b) (−2.141±0.966)+4.506±1.902×subject's age+1.034±0.519×Gender (Female=1, Male=0)+(−5294.063±9075.456)×[ACh / Cr]; (c) (−2.825±1.072)+5.964±2.167×subject's age+1.312±0.562×Gender (Female=1, Male=0)+17.790±58.762×[IL-5 / Cr]+(−9180.821±12700.057)×[ACh / Cr]; (d) (−2.993±1.197)+5.580±2.309×subject's age+1.724±0.719×Gender (Female=1, Male=0)+63.571±73.444×[IL-5 / Cr]+(−0908.523±13606.752)×[ACh / Cr]+(−566.991±636.589)×[ATP / Cr]; (e) (−3.090±1.200)+5.393±2.256×subject's age+1.797±0.717×Gender (Female=1, Male=0)+34.767±56.331×[IL-5 / Cr]+(−562.743±629.316)×[ATP / Cr]; or (f) (−2.650±1.067)+5.516±2.120×subject's age+1.389±0.583×Gender (Female=1, Male=0)+(−4.060±45.238)×[IL-5 / Cr]+(−1.456±6.833)×[NO / Cr]; and wherein a pOAB above a threshold indicates that the subject has a high likelihood of having or developing OAB and a pOAB below a threshold indicates that the subject does not have OAB.

The bladder blood clot remover comprises a hollow sleeve and an inner core, a water inlet is formed in the tail of the hollow sleeve, the head of the hollow sleeve is tilted upwards, a long hole is formed in the back side of the tilted part of the hollow sleeve, and the length direction of the long hole is consistent with the length direction of the hollow sleeve; the water inlet is provided with a closing device; the inner core is inserted into the hollow sleeve from the tail of the hollow sleeve, the diameter of the head of the inner core is larger than that of the middle of the inner core, a groove is formed in the head of the inner core, and the elastic ring is arranged in the groove in a sleeved mode. And when the inner core is inserted into the hollow sleeve from the tail part of the hollow sleeve, a piston effect is formed through the elastic ring and the middle part of the hollow sleeve. The bladder blood clot remover has the advantages of being simple and reasonable in structure, convenient to use, clean in blood clot removal, high in efficiency and the like.

The present invention pertains to the anti-inflammatory therapeutic effect of xantohumol in spinal cord injury (SCI). The continuous administration of xanthohumol for 1-8 weeks to SCI rats resulted in improved results in 4 clinical tests used and in lowering and faster elimination of macrophages from the SCI lesion. Since the infiltration of the SCI lesion by numerous phagocytic macrophages indicates a severe destructive inflammation of extraordinary longevity, administration of xanthohumol is neuroprotective and resulted in a better and faster recovery of the locomotor function and the strength and sensory function in the hind limbs, in a shorter period of paralysis of the urinary bladder and in the recovery of the body weight lost due to the SCI surgery. Since the traumatic brain injury (TBI) involving the white matter, and stroke involving the white matter initiate the severe destructive inflammation as in the SCI, the administration of xanthohumol is expected to be anti-inflammatory and neuroprotective in both brain diseases. Since neurodegenerative diseases including Alzheimer's disease, frontotemporal dementia and Parkinson's disease, immune mediated neuroinflammation including multiple sclerosis and neuromyelitis optica and cerebrospinal infections have inflammatory pathogenesis involving microgliosis and infiltration by macrophages, the administration of xanthohumol is expected to result in therapeutic inhibition of progression of all above diseases as well as of related neurodegenerative, immune mediated and infectious diseases of the brain and of the spinal cord.

The utility model relates to an anti-reflux adjustable speed bladder flusher, the anti-reflux adjustable speed bladder flusher includes an anti-reflux subassembly, an adjustable speed subassembly, a connecting component and a dropper subassembly, the anti-reflux subassembly is connected in the dropper subassembly, a liquid in a liquid bag is suitable for flowing into the dropper subassembly through the anti-reflux subassembly, the anti-reflux subassembly is suitable for limiting the liquid reflux to the liquid bag, the adjustable speed subassembly is set up in the dropper subassembly to control the flow rate of the liquid, the connecting component is set up in the rear end of the dropper subassembly to connect the dropper subassembly and a catheter device.

This application belongs to the field of medical auxiliary devices, specifically relating to an auxiliary device for facilitating bladder irrigation, and more specifically to a positive pressure connector, an adapter connector, and a three-way valve. The three-way valve has a catheter connection end, a urine bag connection end, and an irrigation connection end on its valve seat, used to connect the catheter, urine bag, and irrigation infusion tubing, respectively. By rotating or pressing the valve core, the direction of fluid flow can be directly changed, simplifying the bladder irrigation operation. Simultaneously, a positive pressure connector is provided at the irrigation connection end to prevent bladder fluid from flowing out from the irrigation connection end due to accidental removal of the irrigation infusion tubing, such as when the valve core is not switched to the correct position.

A colpotomy system includes a colpotomy cup, an electromagnet that is coupled to the colpotomy cup (thereby forming an electromagnetic colpotomy cup), and a bipolar electrocautery wand configured for use with the colpotomy cup and electromagnet. The electromagnet is used to generate an inwardly directed force, known as the Lorentz force, to direct the electrocautery wand towards the center of the colpotomy cup. This allows the physician to direct the wand towards the center of the uterine axis and away from the bladder as well as other surrounding structures in the pelvic cavity.

This invention discloses an automatic identification method for pelvic organ prolapse based on deep learning and the PCL line, comprising: S1: acquiring and preprocessing medical images of the pelvic floor region, and simultaneously annotating the bladder, uterus, rectum, and bony anatomical structures to construct a training dataset; S2: constructing and training a multi-objective deep learning segmentation model based on the training data to achieve automatic segmentation of the bladder, uterus, rectum, pubic symphysis, and the two vertebrae from the coccyx; S3: extracting the lowest edge point of the segmented pubic symphysis region and the highest edge point of the two vertebrae from the coccyx region to construct a set of bony key points; S4: connecting the bony key points to automatically generate the pelvic floor reference line (PCL line); S5: analyzing the spatial positional relationship of the bladder, uterus, and rectum relative to the PCL line to obtain the downward displacement feature information of the pelvic organs; S6: automatically determining the degree of pelvic organ prolapse based on the spatial positional relationship. This invention achieves automated identification of the degree of pelvic organ prolapse, reduces subjective errors caused by manual measurement, and improves the consistency, accuracy, and efficiency of the assessment.

The present application relates to the technical field of medical devices, and particularly provides a catheterization device for bladder rehabilitation training of a patient with diabetes combined with heart failure, comprising: a catheter, a lubricating capsule and a pressure capsule; the lubricating capsule is arranged at the top of the catheter and is filled with lubricating liquid; a lubricating pipe is arranged on the lubricating capsule and leads to the outer periphery of the catheter, for supplying lubricating liquid to the outer periphery of the catheter; the pressure capsule is arranged on the catheter and abuts against the lubricating pipe; the pressure capsule is configured to, during the process of inserting the catheter into the urethra, expand or contract by adjusting the pressure in the capsule, so as to block or open the lubricating pipe. According to the scheme of the present application, by arranging the lubricating capsule and the pressure capsule at the top end of the catheter, the opening and blocking of the lubricating pipe can be controlled by the pressure capsule when the catheter moves in the urethra, so as to supply lubricating liquid to the top of the catheter at any time, thereby reducing the resistance of the catheter when moving in the urethra and reducing the discomfort of the patient.