764 results about "Urinary bladder" patented technology

Set forth are vascular valves and servovalves and methods of using the same that may be positioned in the circulatory system without interrupting blood flow to facilitate solid organ transplantation so as to reduce graft organ anoxia and degradation before and after harvesting and storage, thereby minimizing late-term cardiac allograft vasculopathy as a major cause of graft failure. Along the urinary tract, bypassing bladder-generated urge sensation by diverting urine directly from the ureters to a neobladder or collection bag alleviates intractable incontinence, nocturia, urethral syndrome, overactive bladder, dysuria, or frequency. Where the lower tract is missing, a prosthesis can thwart disease and preclude the degenerative metaplastic transition to carcinoma risked when gut is used to construct a conduit for urine, a neobladder, and / or high-maintenance stoma. Druglines to valves and servovalves can directly pipeline-target medication to nidi, anastomoses, or any other trouble spots.

The invention belongs to the technical field of flexible sensing, and particularly relates to a preparation method of an implantable flexible sensor and a bladder urine content wireless monitoring system based on the sensor and a radio frequency mechanism. Wherein the performance of the sensor is improved by utilizing a microporous structure, n-octane is added into TPU to form a porous dielectric layer through a method of different temperatures and different liquid solubility, and the second dielectric layer is added into TPU by using a core-shell structure of silver nanowires and titanium dioxide, so that the anti-interference performance of the pressure-volume sensor is remarkably improved. In addition, the overall structure of the sensor is designed into a semi-bent snake-shaped structure, and the sensor has good pressure-volume performance, sensitivity, restorability and anti-interference performance. The elastic silicone rubber is used for packaging, so that the biocompatibility and practicability of the material are improved, and unstable factors such as body fluid invasion are eliminated. Meanwhile, a wireless sensing system based on a radio frequency mechanism is designed and manufactured, the urine content of the bladder can be wirelessly known from the outside, and related work such as medical care can be helped.

A lumen organ model and an endoscope training system are provided. A luminal organ model (3) is provided with: a model body (11) comprising a hollow lumen body having a lumen surface that simulates at least the lumen of a luminal organ such as the stomach, the large intestine, the bladder, the paranasal sinus, or the uterus; a light source device (13) that emits light in a light-emitting region disposed at at least one predetermined observation site corresponding to a training purpose on the lumen surface of a model body (11) comprising a lumen; and a processor (27) that selectively switches light-emitting regions that emit light by controlling the light source device (13).

The invention discloses a progressive dynamic pressure gradient bladder function regulation and control system and method, and aims to solve the problems of high infection rate, bladder injury risk, complicated operation, lack of dynamic pressure regulation and control and the like in the existing bladder management technology. According to the system, the urinary bladder internal pressure, the urine flow rate and the residual urine volume are monitored in real time through the urodynamic monitor, and the pressure gradient is dynamically adjusted according to the health condition of a patient. Progressive pressure training is adopted in the system, the bladder function is gradually enhanced, meanwhile, an emergency adjustment strategy is introduced, and the safety of a patient is ensured. In addition, the system also integrates machine learning and reinforcement learning algorithms, and realizes personalized treatment according to the treatment history and real-time feedback optimization adjustment strategy of the patient. The system has the advantages of precise regulation and control, personalized treatment, improvement of the comfort level of the patient and the like, and the bladder rehabilitation effect of the spinal cord injury patient is remarkably improved.

The invention discloses a prostate ablation operation needle insertion position construction method and a navigation system, and the method employs a three-dimensional model constructed by an MRI image, and determines the position of a needle insertion point and the number of inserted needles according to the ratio of the longitudinal axis distance between cystamen and verufugu to the diameter of a cylinder of single ablation needle ablation. If the upper and lower diameters of the prostate lateral lobes of the horizontal section corresponding to a single needle insertion point are smaller than 4cm, one needle is inserted into the horizontal plane; if the upper diameter and the lower diameter are greater than or equal to 4cm, entering two stitches; if the maximum diameter of the prostate lateral lobe at a certain longitudinal axis position in the horizontal direction is larger than 1 cm, a needle inserting point is additionally added, and if the length of the part protruding to the middle lobe of the bladder is larger than 1 cm, the needle inserting point is additionally added. The needle inserting point is utilized to enter a surgical navigation system, and the operation is accurately carried out in a unified mode under the guidance of the navigation system. A good treatment effect can be achieved when the hot steam ablation needle is punctured into a hyperplastic prostate near the urethra through the needle insertion point for ablation, the needle insertion point is constructed on the coronal section to ensure the ablation range, and the surgical risk is reduced.

The utility model relates to the technical field of medical instruments, and discloses a bladder irrigation device which comprises a heater set, a hose and a collection bottle set, the hose is communicated with a water outlet of the heater set, the collection bottle set is communicated with the outside of the hose, a one-way valve set is assembled outside the hose, and a first pressing plate is assembled outside the hose. Limiting pipes are connected to the two ends of the first pressing plate, transverse pipes are evenly distributed outside the limiting pipes, trapezoidal blocks are slidably connected to the interiors of the transverse pipes, first springs are connected between the trapezoidal blocks and the transverse pipes, second springs are connected to the two ends of the exterior of the T-shaped arm, and the second springs are connected with the limiting arms. According to the bladder irrigation device, the situation that a traditional control device is prone to being collided outside and flow changes due to internal pressure is avoided, irrigation liquid backflow is avoided through the additionally-arranged one-way valve set, meanwhile, the first pressing plate and the second pressing plate can be rapidly disconnected, and then recycling and reusing are facilitated.

This present disclosure provides devices, systems, and methods for the treatment of conditions pertaining to bladder control. In particular, the present disclosure provides devices, systems, and methods directed to the application of electrical stimulation to the proximal urethra and associated nervous tissue to elicit voiding contractions that normalize bladder function.

The invention discloses a bladder irrigation injection pump, and belongs to the technical field of medical equipment. An irrigation bin, a water storage bin and a waste liquid bin are arranged in a machine shell; a regulator capable of controlling the flushing bin to inject flushing liquid into the bladder of the patient and extracting waste liquid is arranged on the flushing bin; one side of the flushing bin is communicated with the water storage bin and the waste liquid bin; a flushing pipeline capable of conveying liquid into the bladder of the patient and extracting the liquid is arranged on the other side of the flushing bin in a communicating mode, and airflow in the upper space and airflow in the lower space in the flushing bin are compressed and switched through a drainage plate; the bladder flushing device can be matched with a plurality of flow stoppers to control and switch blockage of a pipeline so that flushing liquid can be injected into the bladder of a patient, meanwhile, generated waste liquid can be removed, and new flushing liquid can be introduced into the flushing bin while the waste liquid temporarily stored in the flushing bin is discharged, so that follow-up bladder flushing work can be completed conveniently; and potential safety hazards caused by excessive expansion of the bladder of the patient due to instant filling of the flushing fluid can be further avoided.

The invention provides a transmembrane state evaluation system and method for a bladder three-dimensional form, and is applied to the technical field of data processing. The method comprises the following steps: preprocessing bladder ultrasonic image information of a target patient to generate target ultrasonic image sequence information; processing the target ultrasonic image sequence information to generate a target enhanced ultrasonic image; processing the physiological parameter information of the urinary system of the patient based on the target bladder morphology evaluation model to generate a target physiological status feature; processing the target physiological status features, the target enhanced ultrasound image and the functional image data based on the target bladder morphology evaluation model to generate a predicted CT image of the target patient; and processing the predicted CT image of the target patient and the simulated positioning CT image information of the target patient based on the target bladder form evaluation model in combination with the bladder dynamic image information to generate a bladder three-dimensional form evaluation result.

The invention discloses a negative pressure suction sheath and a negative pressure suction assembly, and relates to the technical field of medical instruments, the negative pressure suction sheath comprises an insertion tube and a sealing element, the insertion tube is internally provided with a containing channel, the sealing element is arranged in the insertion tube, and the sealing element is in sealing fit with the insertion tube and can block the containing channel. The insertion tube can be inserted into the human body, such as kidney and bladder. The sealing piece can isolate the containing channel of the insertion pipe from the external environment, and the insertion pipe is communicated with the ureter and extends to the kidney. At the moment, the sealing piece can prevent the containing channel of the insertion tube from being directly communicated with the outside, so that the pressure in a cavity and organs is effectively maintained, the pressure change amplitude and range of the kidney are reduced, the pressure change in the organs such as the kidney and the like is stabilized, and the probability that the kidney mucosa bleeding due to the pressure change is effectively reduced. Therefore, the onset risk of complications is reduced.

A system and method is disclosed for measuring muscle reflexes (e.g., a bulbocavernosus reflex) as a tool for identifying / diagnosing dysfunctions (e.g., spinal cord abnormalities, bladder voiding dysfunction, and sexual organ dysfunction) non-invasively by using mechanical stimulation. The system and method includes a probe having a predetermined patient contacting portion, wherein when the contacting portion is moved into contact with a particular area of the patient (e.g., the patient's genitals), the contact induces a muscle reflex. The probe detects the pressure resulting from the contacting portion being abruptly and forcibly brought into contact with the particular area. Such detection is used to electronically initiate capture of electrical responses from a plurality of electrodes placed on the patient's skin in proximity to the particular area. Such electrical responses are processed to determine characteristics of the patient's reflexes of one or more muscles adjacent to the electrodes.

A neuromodulation system disclosed herein improves urethral function, provides personalized stimulating parameters, and allows the patients to regain control of their bladders according to several implementations. A neuromodulation system disclosed herein provides bilateral stimulation and sensing, and personalized machine learning classifiers for adaptive stimulation. The system may include one or more electrode leads implanted in a first lateral side of the patient and one or more second electrode leads implanted in a second lateral side of the patient opposite the first lateral side. Mixed urinary incontinence and other conditions are treated using electrical stimulation, according to several implementations.

A urinary catheter includes a catheter tube with a lumen, a proximal end, a distal end and a balloon coupled to the proximal end. The balloon is configured to be positioned in an interior of a bladder. The proximal end is configured to provide flow of urine from the bladder through the catheter lumen bag collects urine from the bladder through the catheter lumen. The drainage bag has an inlet port for receiving urine and an outlet port for draining urine from the drainage bag. The urinary catheter tube includes the proximal end and the proximal end, with a plurality of urine draining holes that receive urine from the bladder and allow it to be transported to and though the urinary catheter tube. One or more sensors included in the urinary catheter and positioned to be in contact with patient's urine. An artificial intelligence engine is coupled to the one or more sensors to receive sensor data, and make recommendations relative to a health of a patient.

The invention discloses a catheter with real-time monitoring and alarming functions and a catheter system, and relates to the technical field of medical instruments, the catheter comprises a catheter main tube, a balloon, an interface, a pressure sensor and a flow sensor; the drainage tube, the flushing tube and the balloon tube penetrate through the inner space of the catheter handle; the drainage cavity electromagnetic valve is matched with the drainage tube penetrating through the catheter handle and is arranged on the catheter handle; the flushing cavity electromagnetic valve is matched with the flushing pipe penetrating through the catheter handle and is arranged on the catheter handle; the control module is used for judging the current normal urination or abnormal urination of the catheter according to the internal pressure of the bladder and / or the urine flow rate, and if the urination is judged to be normal, the drainage cavity electromagnetic valve is controlled to keep the drainage channel communicated; if it is judged that urination is abnormal, the abnormal type is determined by analyzing the internal pressure of the bladder and / or the urine flow rate, and processing including alarming is carried out according to the abnormal type.

A chitosan-heparin nanomotor and a method for producing same are disclosed. A STING agonist-encapsulated urease-based chitosan-heparin nanomotor delivers the STING agonist directly to bladder mucosal cells in the bladder, and thus can induce an immune response.

The invention discloses a transurethral-imbedded bladder urethral anastomosis auxiliary instrument which comprises an outer sleeve, a push-in rod and a puncture rod. The push-in rod is movably mounted on the back of the outer sleeve, and the puncture rod is fixedly mounted at the front end of the push-in rod; a plurality of through holes are formed in the side wall of the outer sleeve in a circumferential array mode, and guide cylinders are fixedly installed at the positions corresponding to the through holes. The push-in rod is controlled to move back and forth to control bending of the puncture rod, and the puncture rod extends through the through hole to puncture the urethra to the outside of the urethra. The suture line is carried to move synchronously through the puncture head arranged at the front end of the puncture rod, and the suture line passes through the puncture head and punctures the exterior of the urethra in a U-shaped mode; a plurality of guide cylinders arranged in a circumferential array and a puncture rod are simultaneously unfolded in an umbrella opening mode, and a suture line is pushed to the outside after passing through the urethra, so that medical staff can conveniently take the suture line sewn on the urethra for pulling the urethra and anastomosing the suture line with the bladder.

Provided herein are methods of treating advanced solid tumors in a subject in need thereof, for example, when the subject has advanced head and neck squamous cell carcinoma, colorectal cancer, non-small cell lung cancer, and bladder transitional cell carcinoma. Also provided herein are methods of treating leukemia (e.g., acute myelogenous leukemia) in a subject in need thereof.

This application relates to solabegron zwitterion useful for the treatment of lower urinary tract symptoms such as, for example, overactive bladder and prostate disorders. Additionally, this application relates to pharmaceutical compositions and methods of treatment utilizing the solabegron zwitterion for treating lower urinary tract symptoms. This application also relates to methods of preparing solabegron hydrochloride from the solabegron zwitterion.

The invention discloses a bladder cancer individualized diagnosis and treatment method based on multi-modal magnetic resonance image fusion and a related device. The method comprises the following steps: acquiring multi-modal image data of a bladder tumor of a patient; extracting quantitative image features related to staging and grading of the bladder cancer according to the multi-modal image data; dynamic curve characteristics of dynamic contrast enhanced magnetic resonance imaging DCE-MRI are extracted according to the quantitative image characteristics, the dynamic curve characteristics comprise a rising slope, peak arrival time and an area under a curve AUC, and heterogeneity of the dynamic curve characteristics in different areas of the bladder cancer tumor is analyzed to form a DCE-MRI characteristic set; the muscle layer infiltration depth and range of the bladder cancer tumor and the surrounding tissue invasion condition are quantitatively evaluated, and the individualized resection depth and range and the operation method of the transurethral bladder tumor are predicted. According to the method, the multi-modal magnetic resonance images are fused, the quantitative image features and the dynamic curve features are extracted, the muscle layer infiltration depth and the surrounding tissue invasion condition of the bladder cancer tumor are quantitatively evaluated, and an individualized diagnosis and treatment scheme is achieved.

The invention discloses an ileum bladder replacement stoma preoperative positioning method based on CT body surface projection. The ileum bladder replacement stoma preoperative positioning method comprises the following steps that S1, region division is conducted on the abdomen; s2, externally adhering developing grid paper to the lower right abdomen of the patient, wherein the developing grid paper is consistent with the human body coordinate system of the lower right abdomen; s3, performing CT scanning on the right lower abdomen of the patient, and establishing a horizontal and vertical coordinate system in an image generated by CT scanning; s4, a plurality of rectus abdominis outer edge positioning points are marked in the foot side direction; s5, inputting the horizontal coordinate values of the plurality of rectus abdominis outer edge positioning points into a laser positioning system on the CT machine tool, finding corresponding longitudinal grid lines on the developing grid paper according to the longitudinal coordinate values corresponding to the horizontal coordinate values and the path information, and dotting and marking on the abdominal skin; s6, the rectus abdominis outer edge positioning points are connected into a line, projection marking is completed, and therefore a final stoma positioning area is determined.

The invention belongs to the technical field of medical image modeling, and particularly relates to a urinary system blood vessel modeling method based on 3D Gaussian splashing and a surgical robot navigation method.The blood vessel modeling method comprises the steps that a data source is preprocessed, and a urinary system blood vessel model is constructed; describing the center line and the section shape of the blood vessel based on a Bezier curve and an NURBS curve, and realizing dynamic 3DGS modeling of the blood vessel; dynamic 3DGS modeling, finite element analysis and computational fluid mechanics are combined, and hemodynamics simulation is achieved through a two-way mapping algorithm of Gaussian parameters and finite element grids. Compared with the prior art, the method solves the problem that in the prior art, due to the fact that a high-precision model for the dynamic characteristics of the blood vessels of the urinary system is lacked, accurate navigation and operation of urinary system interventional operation are difficult. According to the scheme, a high-precision model is constructed for urinary system blood vessels (such as renal arteries and bladder blood vessels) based on the three-dimensional Gaussian sputtering technology, and precise navigation and operation of urinary system interventional operations are effectively assisted.

The invention is suitable for the technical field of urinary surgery, and particularly relates to a bladder pressure control method and system and transurethral surgery operation equipment. Wherein the bladder environment information comprises a bladder environment model and blood vessel distribution information; the bladder pressure is monitored in real time; wherein the bladder pressure reflects the pressure in the bladder in the operation process; obtaining a perfusion speed and a discharge speed based on the bladder pressure; when a pre-operation instruction is received, the perfusion adjustment speed and the discharge adjustment speed are obtained based on the pre-operation instruction and the bladder environment information; wherein the pre-operation instruction is an instruction which is sent by a doctor and is used for controlling a cutting instrument to cut a tumor or a basal wound surface. According to the bladder pressure control method and system and the transurethral surgery operation equipment provided by the embodiment of the invention, the problem that pressure rise in the bladder causes adverse effects on the safety of a patient and postoperative recovery can be solved.

A method for automatically measuring a bladder on an ultrasound image feed, acquired from an ultrasound scanner comprises displaying, on a screen that is communicatively connected to the ultrasound scanner, the ultrasound image feed comprising ultrasound image frames of a bladder; deploying an AI model to execute on a computing device communicably connected to the ultrasound scanner, wherein the AI model is trained so that when the AI model is deployed, the computing device identifies and predicts a view of the bladder, from one of a sagittal view and a transverse view; acquiring, at the computing device, a new ultrasound image during ultrasound scanning; processing, using the AI model, the new ultrasound image to identify and predict the view of the bladder, wherein the prediction is an AI model output; wherein if f the AI model output predicts that the new ultrasound image comprises a sagittal view of the bladder, automatically applying one caliper set along a superior-inferior dimension of the bladder and measuring the superior-inferior dimension; and wherein if the AI model output predicts that the new ultrasound image comprises a transverse view of the bladder, applying two caliper sets along each of a length and a width of the bladder and measuring the length and width thereof.

The invention discloses a negative pressure suction sheath and a negative pressure suction assembly, and relates to the technical field of medical instruments, the negative pressure suction sheath comprises an insertion tube, a sheath base and a sealing element, the sheath base is arranged at the near end of the insertion tube and is communicated with the insertion tube, and the sealing element is arranged on the sheath base, is in sealing fit with the sheath base and / or the insertion tube, and blocks the near end of the insertion tube from being communicated with the outside. The insertion tube can be inserted into a human body, such as a pelvis and a bladder. The sealing piece can isolate the insertion channel from the external environment, and the insertion tube is communicated with the ureter and extends to the renal pelvis. At the moment, the sealing piece can prevent the insertion channel of the insertion tube from being directly communicated with the outside, so that the internal pressure of the insertion channel, the human body cavity and the organs is effectively maintained, the internal pressure change amplitude and range of the human body cavity and the organs are reduced, and the internal pressure change of the human body cavity and the organs is stabilized; and the probability of bleeding of human body cavities and organs due to severe pressure change is effectively reduced, so that the onset risk of complications is reduced.

The invention relates to the technical field of scientific demonstration teaching aids, in particular to a urethral catheterization complication simulation and emergency treatment training robot which comprises a dummy body and further comprises an elastic body and a water tank, the elastic body is arranged on one side of the interior of the dummy body, and a through hole is formed in the side wall of the dummy body and the face, attached to the elastic body, of the dummy body in a penetrating mode; the water tank is arranged on one side in the dummy body and is distributed front and back with the elastic body; a plurality of telescopic cavities are formed in the elastic body, the telescopic cavities are expanded by injecting water into the telescopic cavities so as to extrude the simulation prosthesis and the urethra, the diseases of urethra lumen distortion and walking deviation caused by bladder pressure increase can be simulated, and therefore the emergency treatment capacity of an operator for coping with the conditions can be trained.

The present application relates to the field of medical catheters and specifically discloses a urinary catheter with a special-shaped retainer. The urinary catheter includes a catheter body and a special-shaped retainer. The special-shaped retainer has good elasticity and is internally distributed with a shaped band and a bend and twist inducer. The urinary catheter provided by the present application uses a specially designed elastic chamber or corrugated pipe to support the elastically bent or twisted special-shaped retainer for positioning and fixation in the bladder. The deformation of the special-shaped retainer in the catheter head area can be changed according to usage needs, lowering the catheter port to adapt to the shape of the bladder, allowing urine in the bladder to be fully emptied through the catheter port along the conduction direction, reducing the probability of blockage inside the catheter, reducing the risk of damage and infection to the patient caused by frequent catheter changes, and increasing the safety and convenience of long-term indwelling catheterization.

A method of treating a patient suffering from over-active bladder (OAB) or other urinary or bowel movement disorder includes placing at least one thermal device on an exterior portion of the patient's body proximate to the patient's saphenous nerve or the patient's tibial nerve. The thermal device includes a number of heating elements and a number of cooling elements arranged in a thermal array. The method also includes activating the heating elements and the cooling elements to stimulate the saphenous nerve and / or the tibial nerve to alleviate symptoms of the over-active bladder or the other urinary or bowel movement disorder.

The application discloses a bladder tumor specimen extractor which comprises an adjusting transmission assembly capable of controlling preliminary cutting, a separating assembly capable of separating a tissue part and a liquid part of the bladder tumor and an operating handle. The application belongs to the technical field of bladder tumor surgery. When the bladder tumor temporarily stays on a tissue liquid passing layer, the removed bladder tumor can be punctured by a plurality of groups of puncture heads, so that the tissue part of the bladder tumor is blocked by the tissue liquid passing layer, and the tissue liquid and the plasma part of the bladder tumor can pass through the tissue liquid passing layer and enter a liquid storage bag. After sampling is completed, medical staff can take out the liquid storage bag to sample the tissue liquid and the plasma part of the bladder tumor, and the tissue part of the bladder tumor can be sampled from the tissue liquid passing layer. The application provides a brand-new bladder tumor sampling experience, greatly reduces the possibility of tissue liquid and plasma remaining in the bladder and brings convenience to medical staff.

The application relates to the field of biological preparations, and particularly discloses an immunochromatographic reagent for detecting malignant tumors in urine and application thereof, which is used for solving the problems of poor recognition of tumor specific epitopes, heavy background interference, spectrum overlap and high subjectivity of artificial judgment in the single staining and color development of acridine orange in the detection of urinary exfoliative cells of bladder cancer. The color development reagent comprises A reagent, B reagent, C reagent and D reagent. The A reagent is provided with an antibody complex for target antigens of bladder tumor cells in urine exfoliation and acridine orange. The B reagent comprises a fluorescently labeled secondary antibody composition corresponding to the A reagent and an enzyme-labeled secondary antibody-tyramide deposition amplification composition. In the application, AI imaging analysis is adopted to calibrate layered recognition labels and acridine orange staining negative and positive labels. Through multi-target immunochromatography, two sets of color separation amplification schemes and AI imaging analysis, the application improves the recognition ability of bladder tumor specific epitopes, the image quality and the image analysis accuracy in the detection of urinary exfoliative cells.

This invention provides a transmembrane assessment system and method for three-dimensional bladder morphology, applied in the field of data processing technology. This application preprocesses bladder ultrasound image information of a target patient to generate target ultrasound image sequence information; processes the target ultrasound image sequence information to generate target enhanced ultrasound images; processes the patient's urinary system physiological parameters based on a target bladder morphology assessment model to generate target physiological state characteristics; processes the target physiological state characteristics, target enhanced ultrasound images, and functional imaging data based on the target bladder morphology assessment model to generate a predicted CT image of the target patient; and processes the predicted CT image and simulated localization CT image information of the target patient based on the target bladder morphology assessment model combined with bladder dynamic image information to generate a three-dimensional bladder morphology assessment result.