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3 results about "Urological Disorders" patented technology

Pyrimidin-4(3H)-one derivatives as TRPV4 antagonists

ActiveUS12673946B2DiseaseUrological Disorders
This invention relates to pyrimidin-4(3H)-one derivatives of formula (I),that act as modulators of the TRPV4 receptor. The present invention also relates to processes for the preparation of novel pyrimidin-4(3H)-one derivatives of formula (I) and to their use in the treatment of a wide range of diseases, syndromes, and disorders, in particular, for the treatment of inflammation, pain, and urological diseases or disorders.
Owner:RAQUALIA PHARMA INC

Novel diphenylether derivative and use thereof

The present invention relates to a novel compound and a use thereof for treatment of dysuria, cough and erectile dysfunction. More specifically, the present invention relates to a novel diphenyl ether derivative compound capable of ameliorating and treating dysuria, cough, and erectile dysfunction related thereto by effectively activating a BKCa channel.
Owner:GWANGJU INST OF SCI & TECH

Chemical ablation and method of treatment for various diseases

Embodiments of the present invention provide a device and a method for treating at least one of hypertension, pulmonary arteries, diabetes, obesity, heart failure, end-stage renal disease, digestive disease, urological disease, cancers, tumors, pain, asthma or chronic obstructive pulmonary disease by delivering an effective amount of a formulation to a tissue. In embodiments of the present invention, the formulation may include at least one of a gas, a vapor, a liquid, a solution, an emulsion, or a suspensions of one or more ingredients. In embodiments of the present invention, amounts of the formulation and / or energy are effective to injure or damage tissue, nerves, and nerve endings in order to relieve disease symptoms.
Owner:NEUROTRONIC INC