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3 results about "Sensory potential" patented technology
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A receptor potential, also known as a generator potential, a type of graded potential, is the transmembrane potential difference produced by activation of a sensory receptor. A receptor potential is often produced by sensory transduction. It is generally a depolarizing event resulting from inward current flow.
Compounds for treatment of excitotoxicity
The present invention relates to modulators of canonical-type of transient receptor potential (TRPC) channels, compositions thereof, and methods therewith. The present invention also relates to methods of treating TRPC mediated conditions using such modulators.
Owner:NYRADA PTY LTD
Transient receptor potential vanilloid 6 inhibitors
The present invention relates to methods and uses of preventing or treating cancer The method or use may comprise administration of a cancer therapy together with a compound of Formula (I). In the compound of Formula (I) A is a substituted heteroaryl comprising at least one ring nitrogen; and D includes an optionally substituted: phenyl, N-linked 3,4-dihydro-2H-benzo[b][1,4]oxazinyl, N-linked 10H-phenoxazinyl, indole, pyridinyl, pyrimidinyl, pyrazolo[1,5-a]pyridinyl or thienyl (or R3' and D together form a five or six membered ring). The compound of Formula (I) may be an inhibitor of transient receptor potential vanilloid 6 (TRPV6). The cancer therapy may be a chemotherapeutic agent. The present invention also relates to pharmaceutical compositions and kits comprising a compound of Formula (I) and / or a chemotherapeutic agent.
Owner:UNIQUEST PTY LTD
Compounds for treatment of excitotoxicity
The present invention relates to modulators of canonical-type of transient receptor potential (TRPC) channels, compositions thereof, and methods therewith. The present invention also relates to methods of treating TRPC mediated conditions using such modulators.
Owner:NYRADA PTY LTD