37results about How to "Improve treatment safety" patented technology

The invention provides a multi-layer foam dressing for negative pressure sealing drainage and its manufacturing method. The multi-layer foam dressing for negative pressure sealing drainage includes a negative pressure conduction layer, which is arranged at the lower part of the negative pressure conduction layer for contact with the wound surface or The drainage protection layer in contact with the wound cavity, the negative pressure conduction layer and the drainage protection layer are both porous foam material layers; the negative pressure conduction layer is a hydrophobic porous foam material layer, and the drainage protection layer is a hydrophilic porous foam Material layer, two layers of materials are fixedly connected and the pores are infiltrated and communicated with each other. There are two longitudinal fractures on the multi-layer foam dressing, the longitudinal fractures are located at the position where the negative pressure drainage tube is installed, and one end of the negative pressure drainage tube is installed through the position where the hole of the negative pressure drainage tube is installed to extend to the multi-layer The middle of the foam dressing. The thickness a of the negative pressure conducting layer is 0.5-10 cm, and the pore diameter is 1-2.5 mm. The thickness b of the drainage protection layer is 0.1-3.5 cm, and the pore diameter is 0.2-1 mm. Simultaneously, the invention also provides two methods of making the above-mentioned foam dressing, bonding and compounding. The invention adopts a multi-layer structure, which can effectively improve its negative pressure conduction performance while ensuring the safety of the material, and is not easy to be blocked during use, has stable permeability and excellent therapeutic effect.

The invention relates to the field of a drug preparation, and particularly relates to a powder injection for injection and a preparation method thereof. The powder injection for injection comprises a compound shown in the formula I and a freeze-drying protective additive, wherein the weight ratio of the compound shown in the formula I to the freeze-drying protective additive is (20-50): (100-250). The powder injection for injection provided by the invention is stable in quality, and high in treatment safety, and can be used for effectively treating deterioration of heart failure with a decreased left ventricular systolic function; and the preparation technology of the powder injection for injection is simple and convenient, controllable, and suitable for industrial production.

The invention provides a sealing and flushing teaching simulation device with detection function, the invention is used for solving the technique of pulse flushing and sealing and positive pressure sealing in the prior art, students are unable to practice operational learning, The sealing and flushing teaching simulation device with detection function comprises: a model base, a sealing tube model,a retaining needle assembly and a detecting module. The sealing tube model is embedded into the model base.The sealing model comprises a transparent tube body and a simulated human skin arranged on the transparent tube body, wherein the simulated human skin is provided with a preset insertion hole; the sealing model is inserted into the simulated human skin through the preset insertion hole; andthe preset insertion hole is connected with the detection module. The teaching simulation device can not only simulate the action of irrigation and sealing, but also detect whether the steps of irrigation and sealing meet the requirements, effectively improve the rate of clinical nursing irrigation and sealing technology, improve the safety of clinical infusion treatment and patient satisfaction,and further reduce the medical cost of patients.

The present invention proposes a chimeric antigen receptor. The chimeric antigen receptor comprises: an extracellular region comprising a single-chain antibody and a hinge region, the single-chain antibody comprising a heavy chain variable region and a light chain variable region of a single-chain antibody, the single-chain antibody The chain antibody specifically recognizes the antigen human CD19, and the hinge region includes the extracellular segment of the human CD8α molecule containing 55 amino acid residues and 3 additional amino acid residues AAA, and the AAA is located at the N of the extracellular segment of the human CD8α molecule end; the transmembrane region, the transmembrane region includes the transmembrane segment of the human CD8α molecule, the transmembrane segment of the human CD8α molecule is connected to the hinge region of the extracellular region, and embedded in the cell membrane of the T lymphocyte; The intracellular region, the intracellular region includes the intracellular segment of the human CD8α molecule containing 7 amino acid residues, the intracellular segment of the 4‑1BB molecule and the intracellular segment of the CD3ζ chain, the intracellular region and the transmembrane region The human CD8α molecule is linked by a transmembrane segment.

The invention provides an auxiliary channel film sleeve for use in endoscopical therapy. The auxiliary channel film sleeve comprises a transparent cap and a film sleeve, wherein the transparent cap has an annular hollow structure; a transparent cap wall is fixed to the end part of the film sleeve; the two ends of the film sleeve are opened; the diameter of the transparent cap is adaptive to the diameter of an endoscope; the transparent cap can be hooped on the head of the endoscope, and is used for driving the film sleeve to enter a human body through the endoscope. The diameter of the endoscope varies, so that a plurality of transparent caps matched with the endoscope can be manufactured and hooped on the head of the endoscope. The film sleeve for use in combination with endoscopes such as colonoscopies, gastroscopes and colposcopes can be sleeved at the head end of the endoscope and brought into the human body. During therapy, a suction apparatus, a flushing tube, a pair of hot biopsy forceps and the like can be inserted through the auxiliary channel film sleeve, so that convenience is brought to treatment, the treatment process is simplified, the surgery efficiency is increased, and the therapy safety is enhanced.

The invention provides a breathing skin bag, which belongs to the field of instruments. The breathing bag includes a balloon, an installation tube, a safety valve, a duckbill valve, an exhalation valve and a ventilation piece. One end of the installation tube is connected to one end of the balloon, and the safety valve, the duckbill valve and the exhalation valve are connected to the installation tube. The exhalation valve has an air passage 1, and also includes a treatment part 2. The treatment part 2 has a treatment drug. When the one-way valve flap of the duckbill valve is opened, the treatment part 2 is broken open and the treatment drug leaks from the treatment part 2. Enter In the first air passage, the first air passage communicates with the ventilation member. The breathing skin bag solves the problems of poor treatment safety and high internal visceral load of the existing intravenous injection for treating asthma.