40 results about "Pleural effusion" patented technology

The invention relates to the technical field of hydrops quantitative evaluation, and discloses an ultrasound-based pleural hydrops quantitative evaluation system, which comprises an image acquisition module, a boundary division module, a trajectory analysis module, a feature judgment module, a mode classification module and a quantitative evaluation determination module, the positioning module is used for positioning an area which deforms along with breathing movement in the ultrasonic image sequence, and dividing a suspected effusion cavity boundary based on the consistency of a deformation mode; the trajectory analysis module is used for analyzing moving trajectories of the suspected effusion cavity boundary at different breathing phases and extracting regularity features and amplitude change features of the moving trajectories; the feature judgment module is used for judging the mechanical coupling state of the suspected effusion cavity and the surrounding lung tissue according to the combination of the regularity feature and the amplitude change feature; according to the method, the comprehensiveness and accuracy of quantitative evaluation of the pleural effusion are remarkably improved, and a more valuable decision basis is provided for clinical diagnosis and treatment.

This invention belongs to the field of medical device technology, specifically relating to a fluid self-excited vibration anti-blockage chest drainage tube and an anti-blockage drainage method. It includes a drainage tube body made of medical flexible material; 3-5 chamfered drainage holes are evenly distributed circumferentially at the distal end of the drainage tube body, with rounded edges at the holes having a radius of 0.3-0.5 mm; a threaded connector for quick connection with an external drainage device is fixedly provided at the proximal end of the drainage tube body. The core of this invention, the turbulence section and the variable cross-section oscillation section, are independently arranged along the tube axis, completely avoiding the low vibration efficiency and easy jamming problems caused by the simultaneous placement of the vibrating component and the variable cross-section structure in the prior art. The self-excited vibration generating cavity formed relies solely on the fluid kinetic energy of the pleural effusion or gas to drive the vibration, requiring no external power, significantly reducing equipment complexity and infection risk.

This invention discloses a device for pleural effusion drainage, relating to the field of pleural effusion drainage technology. It includes a housing, with an air pump mounted on the top, a suction tube inserted into the bottom of the air pump, and an air outlet on one side of the air pump. A pneumatic mechanism is installed on the inner bottom wall of the housing, comprising an air cylinder fixedly connected to the housing, a piston slidably connected inside the air cylinder, a connecting rod fixedly connected to the top of the piston, and a linkage mechanism mounted on the top of the connecting rod. This pleural effusion drainage device generates negative pressure inside the air cylinder. Under this negative pressure, the piston slides downwards, causing the two edges of the drainage bag to move away from each other, expanding the internal space of the drainage bag and thus creating negative pressure inside. This draws pleural effusion into the drainage bag. The design of the pneumatic mechanism and linkage structure isolates the pleural effusion from the outside environment, reducing the odor of the drained pleural effusion.

The application discloses a tubeless thoracic surgery pleural effusion monitoring device and relates to the technical field of pleural effusion monitoring. The tubeless thoracic surgery pleural effusion monitoring device comprises a body and a movable monitoring mechanism. The movable monitoring mechanism comprises an electric telescopic rod, the telescopic end of the electric telescopic rod is fixedly connected with a linear driver, the output end at the bottom of the linear driver is fixedly installed with an X-ray detector, the side of the surface of the linear driver is installed with an auxiliary assembly, the auxiliary assembly comprises a connecting base block and a pressing guide rod, the top end of the pressing guide rod and the side of the surface of the support are fixedly installed with an elastic telescopic damping rod, the bottom end of the pressing guide rod is fixedly connected with a rectangular sheet, the side of the bottom of the rectangular sheet is fixedly connected with a limiting piece, the middle of the bottom of the rectangular sheet is fixedly connected with a flexible pad, the purpose of preventing shaking is achieved, the patient can be pressed and held, a stable posture is maintained, and the chest cavity effusion can be accurately monitored, and the device is safe and reliable.

The utility model innovatively provides a kind of chest drainage bottle, including chest drainage bottle, there is storage cavity and hardening cavity in chest drainage bottle, there is partition between storage cavity and hardening cavity, hardening agent is stored in hardening cavity, partition is detachably set in chest drainage bottle;Storage cavity and hardening cavity are set in chest drainage bottle, hardening agent is stored in hardening cavity, using hardening agent, the pleural effusion in storage cavity can be hardened, it is convenient to handle pleural effusion, it is convenient to realize the recovery treatment of pleural effusion;And using partition detachably set, it is convenient to realize that hardening agent is poured into storage cavity.

The utility model discloses a pleural effusion suction device for cardiovascular surgery, including base, the base top one side is installed with micro negative pressure pump, the micro negative pressure pump top is installed with U type communication pipe, U type communication pipe one end is installed with effusion collection bottle, the base top other side places and is provided with the limit drag tray, the limit drag tray bottom and base inboard all are provided with magnetic attraction piece, through the collocation setting of U type communication pipe, effusion collection bottle, U type open slot, disposable flow guide pipe, when the effusion in effusion collection bottle is more, can replace empty effusion collection bottle in time, through setting up magnetic attraction piece in limit drag tray bottom and base inboard, when personnel place effusion collection bottle to limit drag tray inboard, it is not easy to pour, through the collocation setting of tail plug, pen barrel type suction head, top cover, connector, outer thread pipe, make disposable flow guide pipe and puncture needle install more stable, and personnel handheld pen barrel type suction head carry out puncture drainage suction liquid more stable.

The invention discloses a pleural effusion suction device, relates to the technical field of pleural effusion suction devices, aims to solve the technical problem that the pleural effusion suction device is easy to block, and comprises a machine body, a closed channel, a rotating stand, a roller unit, a flow guide tube assembly and a rotating mechanism. The three roller units are driven by the rotating frame to circularly move along the closed channel, and the functions of compaction pushing, radial vibration anti-blocking and separation resetting are achieved on the stations corresponding to the first arc groove, the inclined guide groove A, the second arc groove, the third arc groove and the inclined guide groove B. The stations work cooperatively, and the working efficiency is improved. The second arc groove drives the rolling wheel unit to do radial reciprocating motion to generate deformation disturbance on the flow guide pipe assembly, the deposition risk of hydrops on the inner wall of the flow guide pipe assembly is effectively reduced, and therefore long-acting and stable pleural effusion drainage is achieved on the premise that the operation burden of medical staff is not increased, and the technical problem that the pleural effusion suction device is prone to being blocked is solved.

1. Name of the product in this design: Fluid drainage bottle (intensive care unit). 2. Intended use of this design: for pneumothorax, pleural effusion and closed thoracic drainage after surgery. 3. The key design feature of this product is its shape. 4. The image or photograph that best illustrates the design's key points: a 3D model. 5. The design for which protection is sought includes color.

The invention provides a thoracic surgery postoperative pleural effusion drainage nursing device, and belongs to the technical field of thoracic surgery nursing. A postoperative pleural effusion drainage nursing device for the thoracic surgery department comprises a wearing frame and a drainage bottle. The force storage extrusion assembly is used for assisting medical staff to automatically extrude the drainage tube, and the force storage assembly is connected with the drainage tube and the wearing frame. According to the scheme, the postoperative pleural effusion drainage nursing device for the thoracic surgery department is provided with the force storage extrusion assembly, the drainage tube can be regularly extruded by means of automatic force storage by means of expansion and fluctuation of the thoracic cavity when a patient breathes, next force storage extrusion can be carried out along with respiratory reset of the patient after each extrusion, manual operation of medical staff is not needed, and operation is convenient. According to the drainage tube fixing device, the workload of medical staff is effectively relieved, a certain limiting effect on the drainage tube is achieved, movement and traction of the drainage tube in the using process are reduced, and the postoperative recovery process of a patient is further guaranteed.

The invention discloses a differential diagnosis and prognosis evaluation method for a pleural effusion microbiome based on metagenome sequencing and application, belongs to the technical field of bioinformatics, and discloses a method for analyzing the microbiome of a pleural effusion sample, and the method comprises the following steps: carrying out metagenome next-generation sequencing on an in-vitro pleural effusion sample to obtain a sequencing reading; performing bioinformatics analysis on the sequencing reading, and determining microorganism composition information of the pleural effusion sample based on a verification result; by establishing a unified mNGS experimental process and a parallel bioinformatics analysis path, two kinds of technical information of different dimensions, namely microbiome structural characteristics and host genome copy number variation (CNV), are synchronously output from single sequencing data, and the defect that microbiological analysis and genome analysis need to be carried out in batches in the prior art is overcome.

The invention provides a closed drainage tube for special pleural effusion and a closed drainage dredging method for the thoracic cavity. The closed drainage tube for the special pleural effusion comprises a drainage tube body, an auxiliary communication block, a magnetic cleaning strip and an iron ring. And the drainage tube can be respectively connected with in-vivo and in-vitro drainage systems of a patient. The auxiliary communication block is provided with a compensation channel communicated with the drainage tube, the compensation channel and the drainage tube jointly form a drainage channel, and a path is provided for effusion drainage. And the auxiliary communication block is provided with a storage space which can be communicated with the compensation channel. And the magnetic cleaning strip is arranged in the storage space. And the iron ring can be sleeved on the drainage tube and the auxiliary communication block. And the iron ring can drive the magnetic cleaning strip to move into the drainage channel from the storage space and drive the magnetic cleaning strip to clean the inner wall of the drainage channel in the drainage channel when the drainage channel is dredged. According to the closed drainage tube for the special pleural effusion, the effusion attached to the inner wall of the drainage tube is fully scraped off under the closed condition, the smooth service life of the drainage tube is effectively prolonged, and the blocking recurrence rate is reduced.

The invention relates to the technical field of medical instruments, in particular to a portable multi-pipeline thoracic closed drainage tube which comprises a shell, a fixing tube is connected to the interior of the shell, a hose is connected to the outer side of the fixing tube, a hydrops assembly is arranged at the bottom of the shell, and an exhaust assembly is arranged at the top of the shell. Through the arrangement of the hydrops assembly, a special one-way airtight structural component can be adopted to prevent gas from flowing back to the thoracic cavity, the negative pressure of the thoracic cavity and the drainage of pneumatosis in the thoracic cavity can still be maintained after a water-sealed bottle is abandoned, the effects of portability and safety are achieved, and a pneumothorax patient can be prevented from being hospitalized and recuperated home after catheterization; the drainage device can be pulled out in an outpatient service after the illness state is improved, the cost of a patient is reduced, a drainage bag or a water-sealed bottle can be externally connected to the connector for the patient with pleural effusion, the connector is of a threaded structure, and meanwhile a conversion connector component of a drainage tube of a traditional water-sealed bottle structure can be provided.

According to the lung fibrous tissue removing device, starting from the source, abnormal fibrous grids in a pleural cavity are safely and effectively broken, ablated or cut off in a physical or energy mode, all separated small rooms are broken through, and a plurality of independent areas are fused into a whole. Therefore, all effusion in the thoracic cavity can be thoroughly drained only through one-time puncture or a few times of puncture. The operation time can be remarkably shortened, the pain of a patient can be relieved, lung trauma and various complications caused by multiple times of puncture can be fundamentally avoided, the treatment effect and safety of pleural effusion, especially complex atrial effusion, are greatly improved, and important clinical value and social significance are achieved.

The invention relates to the technical field of drainage assistance, in particular to a pleural effusion drainage assisting device which comprises a fixing plate and a clamping plate, a plurality of extrusion units are fixedly connected to the bottom face of the fixing plate, each extrusion unit comprises a seat plate, and fixing rods are fixedly connected to the two sides of one end of the bottom face of each seat plate; and two opposite transverse clamping plates are arranged below the seat plate. According to the drainage tube dredging device, through the arrangement of the transverse clamping plate and the vertical clamping plate, when the clamping plate passes through the extrusion units, the transverse clamping plate and the vertical clamping plate are driven to repeatedly extrude the drainage tube to cause surging of liquid in the drainage tube, so that the drainage tube is dredged, and the drainage tube is sequentially clamped after the drainage tube is transversely and vertically extruded by the multiple extrusion units; when the clamping plate is inserted from the front end of the sliding rail again and dragged towards the rear end, the drainage tube is restored to the cylindrical state from the extruded flat state, accumulated liquid is sucked in from the front end of the drainage tube, and therefore the drainage efficiency of the drainage tube is improved.

This invention relates to the field of medical device technology, providing a closed thoracic drainage control device for thoracic surgery. The device includes a drainage bottle with a base fixedly connected to its bottom. The inner wall of the base is equipped with an anti-tipping component to improve the stability of the drainage bottle. An inlet tube for introducing pleural effusion and gas is fixedly connected to the top left side of the drainage bottle. An anti-backflow component is installed inside the inlet tube to prevent backflow of the effusion. An exhaust pipe for discharging gas from the cavity is fixedly connected to the top right side of the drainage bottle. An adjustment pipe is arranged parallel to the right side of the exhaust pipe. The anti-tipping trigger component automatically isolates each chamber upon tipping, preventing fluid cross-contamination. A purely mechanical pressure regulating mechanism infinitely adjusts the negative pressure and adaptively maintains stability. The pressure relief component automatically alarms and resets hydraulically in case of overpressure. The entire device requires no power supply, has a compact structure, and is easy to operate, significantly improving the safety and portability of the drainage device.

The application belongs to the technical field of biological medicine, and discloses a biomarker for evaluating the degree of pleural adhesion of tuberculous pleural effusion (TPE) and application. The application provides a biomarker for evaluating the degree of pleural adhesion of tuberculous pleural effusion, wherein the biomarker comprises dsDNA (double-stranded DNA) in the pleural effusion. The biomarker can be used to more conveniently and economically diagnose TPE, and further evaluate the severity of pleural adhesion of TPE patients, thereby guiding anti-tuberculosis and anti-adhesion treatment in the clinic.

The utility model belongs to the technical field of negative pressure aspirators, and particularly relates to a pleural effusion suction negative pressure aspirator which comprises a liquid storage bottle, a first connector and a second connector are arranged on the liquid storage bottle, the first connector is connected with a puncture needle assembly through a drainage tube, and the second connector is connected with a negative pressure assembly through a connecting tube. The puncture needle assembly comprises a needle seat connected with the drainage tube and a puncture needle connected with the needle seat, the negative pressure assembly comprises a vacuum pump connected with the connecting tube, a controller electrically connected with the vacuum pump and a piezoresistive sensor arranged in the needle seat, and the piezoresistive sensor is electrically connected with the controller. The controller controls the power of the vacuum pump according to the negative pressure information of the piezoresistive sensor, the negative pressure is detected through the piezoresistive sensor, and the detected pressure information is transmitted to the controller. When the controller detects that the negative pressure is abnormal, the power of the vacuum pump can be automatically adjusted, and then the negative pressure is automatically adjusted, so that the flow velocity stability is controlled.

This invention discloses a method and related equipment for constructing an ultrasound diagnostic training model for lung diseases. The method includes: acquiring magnetic resonance imaging (MRI) data of the chest of a target subject; performing three-dimensional reconstruction and structural segmentation on the MRI data to generate a three-dimensional anatomical digital model of the lung, including the lung parenchyma, pleura, diaphragm, ribs, and mediastinal structures; optimizing the structure, layering the model, and annotating material properties using three-dimensional modeling software to generate a three-dimensional printing model file; constructing a physical lung training model based on the three-dimensional printing model file using a multi-material three-dimensional printing device, and setting pathological simulation structures in a preset area of ​​the model to simulate the ultrasound imaging characteristics of diseases such as pulmonary consolidation, pleural effusion, pneumothorax, and pulmonary edema. The training model constructed by this invention has a realistic anatomical structure, is reusable, and can present typical lung ultrasound imaging characteristics under real ultrasound equipment.

The invention relates to the technical field of medical education equipment, and particularly discloses a health major ambulance group comprehensive training dummy which comprises a dummy body, a simulation box is arranged on the dummy body, a sliding baffle is slidably clamped on the simulation box, and an operation opening penetrating into the simulation box is formed in the sliding baffle. Two first fixing rods are installed in the simulation box, a pleural effusion storage box is fixedly connected between the two first fixing rods, a first opening is formed in the side wall of the pleural effusion storage box, and a pleural skeleton simulation device used for simulating a pleural skeleton structure in a puncture path is arranged on the pleural effusion storage box; and a puncture epidermis replacing device for automatically replacing the puncture epidermis at the thoracic cavity skeleton simulating device is arranged in the simulating box, so that the technical problems that the efficiency is low and the operation is tedious due to the fact that the used puncture epidermis and pleura layer need to be manually replaced in the thoracic cavity puncture simulating process of an existing simulator are solved.

1. Name of the product in this design: Thoracic surgical drainage device. 2. Purpose of this design: For use in thoracic surgery nursing procedures to drain and drain pleural effusion from patients. 3. The key design feature of this product is its shape. 4. The image or photograph that best illustrates the design's key points: 3D view 1.

The phagocytic cell AI identification training, detection and proportion detection analysis method comprises the following steps: preprocessing a sample to obtain a microscopic sample; shooting a microscopic examination sample to obtain a microscopic examination sample image; identifying and labeling phagocytic cells in the microscopic examination sample image to obtain a phagocytic cell labeling picture; and AI training is carried out by using the labeled picture to obtain an AI identification feature data set A, and the AI identification feature data set A comprises phagocytic cell AI identification feature data. Identifying the microscopic examination sample image by using an AI identification algorithm, identifying phagocytic cells in hydrothorax and ascites in a selected area S1 of the image, obtaining the number NUM1 of the phagocytic cells, and obtaining the number NUM2 of phagocytic cells; in a microscopic examination sample, the content of phagocytic cells in unit volume is equal to NUM1 / V1. The ratio of phagocytic cells is equal to NUM1 / NUM2.

The invention discloses a pleural effusion suction device for the surgery department, and belongs to the technical field of pleural effusion suction, the pleural effusion suction device comprises a main body module and a feedback module, the main body module comprises a needle cylinder, a piston is arranged in the needle cylinder, and a damping ring making contact with the inner wall of the needle cylinder is arranged on the outer surface of the piston; through arrangement of a mounting rod, a right trapezoid groove, a sleeving rod, a force limiting assembly, a control assembly, a limiting assembly and a tension spring, integrated mechanical control over the liquid pumping force and the blocking state is formed, a damping ring limits the moving speed, the tension spring cannot pull a piston during blocking, the force limiting assembly is lifted to abut against the inner wall of a needle cylinder, and the control assembly cannot be pressed downwards; excessive force application is mechanically limited, explosive liquid extraction caused by needle shaking and displacement, tissue damage and blockage falling is avoided, meanwhile, the blockage state is clearly fed back through pressing of the control assembly, the potential safety hazard that in the prior art, manual experience is relied on is avoided, and the liquid extraction safety is improved.

The present disclosure discloses a library construction method for detecting endometrial cancer-related gene mutations based on high-throughput sequencing, and belongs to the field of biotechnology. The method can detect the mutation types of endometrial cancer-related genes MSH2, PMS2, MLH1, MSH6 EPCAM, TP53, POLE, and PTEN in surgically removed fresh pathological tissues, formaldehyde-fixed and paraffin-embedded pathological tissues, paraffin sections, and specimens of whole blood, plasma, serum, and pleural effusion, etc. It may be used for multiple target sequences in a single tube to quickly complete the library construction. The entire library construction process only takes 3 hours, and the manual operation only needs 30 minutes. Combined with high-throughput sequencing, the platform may effectively solve the current difficulty in the detection of somatic multi-gene all-exon mutations in clinical endometrial cancer samples based on small numbers of clinical samples, and the cost is low.

The invention relates to a body position auxiliary supporting device for pleural effusion puncture treatment, and belongs to the technical field of medical instruments. The position auxiliary supporting device for pleural effusion puncture treatment comprises a hip plate, a back plate, a web plate and an arm plate, the hip plate is used for supporting the hip of a patient, the back plate is hinged to one side of the hip plate, and the web plate is hinged to the side, away from a back plate assembly, of the hip plate; the arm plate is arranged on the side, away from the hip plate, of the web, used for supporting arms of a patient and perpendicular to the web. The back plate and the web plate are configured to rotate relative to the hip plate so as to achieve conversion of the supporting device between a chair supporting state and a bed supporting state. When pleural effusion puncture treatment is carried out, the device is in a treatment chair shape, the supporting height can be adjusted according to the height and the body shape of a patient, and the comfort of the patient is improved while normal puncture is guaranteed; after a pleural reaction of a patient occurs, the device can be converted into a simple sickbed form from a treatment chair form, so that the patient can be treated in time, and deterioration of the disease is avoided.

The invention discloses an EIT region segmentation and quantitative analysis method and system based on ultrasonic anatomy calibration, and belongs to the field of medical image and respiratory physiology monitoring. Processing the ultrasound image to identify anatomical markers such as a rib line, a pleural line and a diaphragm line; performing multi-modal image registration based on the physical coordinates and the common anatomical anchor points; mapping the anatomical landmark to an EIT grid; performing hierarchical constraint region segmentation on the EIT grid; and calculating an impedance average value and a tidal impedance variation based on a segmentation result. According to the method, individualized accurate region segmentation of the EIT image is achieved through ultrasonic anatomical structure calibration, data pollution is avoided, the EIT can provide a quantitative report with a clear anatomical identifier, and the application value and reliability of the EIT in clinical scenes such as pulmonary ventilation efficiency evaluation, pulmonary edema monitoring and pleural effusion quantification are greatly improved.

This invention discloses a Mycoplasma caprineis subspecies Mccp NM strain and its applications. Whole-genome alignment of this strain revealed 422 missense mutations, 132 frameshift mutations, and several key insertion / deletion variations compared to the existing vaccine strain C87001. In virulence studies, at a concentration of 1×10⁻⁶... 9 In healthy, susceptible goats, intratracheal injection at a CCU / mL dose resulted in all experimental goats exhibiting typical symptoms of caprine contagious pleuropneumonia. Autopsy revealed pleural effusion and liver-like lesions in the lungs. The inactivated vaccine prepared using this strain demonstrated good safety in goats. Challenge protection tests showed that the vaccine of this invention provided 100% protection against homologous challenge with the NM strain and 80% protection against the heterologous C87002 strain, while commercially available vaccines offered only 40% protection against the NM strain. This invention overcomes the deficiency of existing vaccines in providing insufficient protection against clinical variants, offering an effective technical reserve and candidate vaccine for addressing immunization failure caused by Mccp antigen mutations.

Provided is a method for culturing a sample of cells, which includes circulating epithelial cells, peripheral blood mononuclear cells (PBMC), or body fluid-derived cell samples (e.g. blood, ascites, pleural effusions, cerebrospinal fluids, perfusion fluids, sputum, and urine), or liquid biopsy-derived cell samples in presence of Bone Morphogentic Protein (BMP) inhibitor, a mitogenic growth factor, and a Wnt agonist, when culturing the circulating epithelial cells and relevant blood cells. Also provided is use of cell medium having a BMP inhibitor, a mitogenic growth factor, and a Wnt agonist in obtaining a cell culture of circulating epithelial cells, PBMC and body fluid-derived cells.

The invention relates to the field of medical instruments, in particular to a portable rapid pleural effusion detection device. A portable rapid pleural effusion detection device comprises a box-shaped shell, an insertion groove is formed in the shell, and a first notch is formed in the position, on the end face of one side of the shell, of the insertion groove; a display screen is arranged on one outer wall of the shell, a central processing unit is integrated in the shell, and the display screen is in communication connection with the central processing unit; the chip is inserted into the slot from the first notch, the chip is made of a light-transmitting material, a plurality of detection channels are arranged in the chip, and different detection reagents are respectively placed in at least one part of the detection channels; the system further comprises a plurality of detection devices, and any detection device is in wireless communication connection with the central processing unit. The technical problem existing in the prior art is solved, and a portable rapid pleural effusion detection device capable of achieving rapid and multi-parameter is urgently needed in the field of medical instruments so as to assist doctors in real-time diagnosis and clinical decision making.

A pleural catheter device (10) includes: a catheter (20) that drains pleural effusion of a subject; an electrode (22) that is provided to the catheter (20) and applies electrical stimulation to a respiratory muscle or a phrenic nerve of the subject; and a controller (32) that performs control of the electrical stimulation by the electrode (22).

A method for treating pleural effusion includes: administering a Chinese medicine composition to a subject in need thereof; wherein, the Chinese medicine composition is an extract of a first mixture comprising Poria, Polyporus, Rhizoma Alismatis, Atractylodis Rhizoma, Pimenta Officinalis, Zingiberis Rhizoma, Aconiti Lateralis Radix praeparata, Phellodendron amurense, Angelica sinensis, Astragalus Membranaceus, Stephaniae Tetrandrae Radix, Descurainiea Semen, Ephedra Sinica, Armeniacae Semen amarum, Ginseng Radix et Rhizoma, Anredera Cordifolia and Velvet Antler.