28 results about "Left atrial pressure" patented technology

Coaptation assist device for repairing cardiac valves and associated systems and methods are disclosed herein. A coaptation assist device configured in accordance with embodiments of the present technology can include, for example, a fixation member configured to press against cardiac tissue proximate to a native valve annulus, and a stationary coaptation structure extending away from the fixation member. The coaptation structure can include an anterior surface configured to coapt with a first native leaflet during systole and a posterior surface configured to displace at least a portion of a second native leaflet. The device also includes at least one sensor configured to detect parameters associated with at least one of cardiac function and device functionality. The sensors can be pressure sensors configured to detect left atrial pressure and / or left ventricular pressure.

Systems and methods for delivering a device for regulating blood pressure across a patient's atrial septum are provided. The delivery apparatus may include a first catheter, a hub having one or more engagers disposed thereon, the one or more engagers configured to releasably engage with a first expandable end of the shunt in a contracted delivery state within a lumen of a sheath, and an second catheter extending through a center lumen of the first catheter and the hub, wherein the first catheter, the hub, and the second catheter are independently moveable relative to the sheath. The inventive devices may reduce left atrial pressure and left ventricular end diastolic pressure, increase cardiac output, increase ejection fraction, relieve pulmonary congestion, and lower pulmonary artery pressure, among other benefits. The inventive devices also may be used to treat subjects having heart failure, pulmonary congestion, or myocardial infarction, among other pathologies.

A method of reducing left atrial pressure is provided for treating diastolic heart failure. A puncture catheter is advanced into a coronary sinus for creating an opening in a wall between the coronary sinus and a left atrium of a heart. A cauterizing tool may be used to create a controlled scarring pattern in the tissue along the opening. After the opening is created, a blood flow path is provided from the left atrium to the coronary sinus for reducing blood pressure in the left atrium and thereby alleviating symptoms of heart failure. If necessary, a shunt device may be implanted within the opening to ensure that the blood flow path remains open.

A device for regulating blood pressure between a patient's left atrium and right atrium comprises an hourglass-shaped stent comprising a neck region and first and second flared end regions, the neck region disposed between the first and second end regions and configured to engage the fossa ovalis of the patient's atrial septum, and a drug-eluting biodegradable material that biodegrades over time to release a drug that limits tissue overgrowth. The inventive device also may include a biodegradable material that biodegrades to offset flow changes caused by tissue overgrowth. The inventive device may reduce left atrial pressure and left ventricular end diastolic pressure, and may increase cardiac output, increase ejection fraction, relieve pulmonary congestion, and lower pulmonary artery pressure, among other benefits.

A device for regulating blood pressure between a patient's left atrium and right atrium comprises an hourglass-shaped stent comprising a neck region and first and second flared end regions, the neck region disposed between the first and second end regions and configured to engage the fossa ovalis of the patient's atrial septum; and a one-way tissue valve coupled to the first flared end region and configured to shunt blood from the left atrium to the right atrium when blood pressure in the left atrium exceeds blood pressure in the right atrium. The inventive devices may reduce left atrial pressure and left ventricular end diastolic pressure, and may increase cardiac output, increase ejection fraction, relieve pulmonary congestion, and lower pulmonary artery pressure, among other benefits. The inventive devices may be used, for example, to treat subjects having heart failure, pulmonary congestion, or myocardial infarction, among other pathologies.

A blood flow pathway is formed between a left atrium and a coronary sinus for relieving elevated left atrial pressure. The treatment method includes providing first and second delivery catheters, wherein a medical device is carried by the second delivery catheter. A side outlet opening of the first delivery catheter is positioned within the coronary sinus and oriented toward a left atrium. An anchor on the first delivery catheter contacts an inner surface of the coronary sinus for stabilization. A distal portion of the second delivery catheter is advanced through the side outlet opening. A puncture component is then passed through a target wall portion for creating the blood flow pathway. The medical device is positioned in the opening.

A blood flow pathway is formed between a left atrium and a coronary sinus for relieving elevated left atrial pressure. The treatment method includes providing first and second delivery catheters, wherein a medical device is carried by the second delivery catheter. A side outlet opening of the first delivery catheter is positioned within the coronary sinus and oriented toward a left atrium. An anchor on the first delivery catheter contacts an inner surface of the coronary sinus for stabilization. A distal portion of the second delivery catheter is advanced through the side outlet opening. A puncture component is then passed through a target wall portion for creating the blood flow pathway. The medical device is positioned in the opening.

A blood flow pathway is formed between a left atrium and a coronary sinus for relieving elevated left atrial pressure. The treatment method includes providing first and second delivery catheters, wherein a medical device is carried by the second delivery catheter. A side outlet opening of the first delivery catheter is positioned within the coronary sinus and oriented toward a left atrium. An anchor on the first delivery catheter contacts an inner surface of the coronary sinus for stabilization. A distal portion of the second delivery catheter is advanced through the side outlet opening. A puncture component is then passed through a target wall portion for creating the blood flow pathway. The medical device is positioned in the opening.

The present disclosure relates to a device assembly and a method for treating heart failure by normalizing elevated blood pressure in the left atrium of a heart of a mammal. Disclosed herein is a transcatheter interatrial septum excision device assembly configured to create a sized interatrial aperture between the right and left atria of a heart for the relief of elevated left atrial pressure. The device assembly comprises a delivery catheter, a tissue stabilizer attached to a first catheter having a central lumen and a penetrating tip that permits passage of a guidewire, and a cutter attached to a second catheter having a central lumen that permits passage of the first catheter. Alternative configurations comprise a (third) catheter having a central lumen that permits passage of the aforementioned components to and from the right atrium, a tissue retention mechanism and an optional coaxial alignment mechanism.

The present invention provides a control system and method for personalized treatment of a left ventricular assist device, relating to the field of artificial heart technology. The method comprises: for each cardiac cycle, a Starling-like regulator receives a left atrial pressure signal fed back by a physiological feedback module, and outputs a desired cardiac index based on the patient's body surface area; a pump flow quantification feedback module calculates the pump flow in real time based on the rotational speed and current of the left ventricular assist device, and outputs the feedback cardiac index in combination with the patient's body surface area; calculates the deviation between the desired cardiac index and the feedback cardiac index, inputs the deviation into a controller, and the controller determines the output current increment based on the deviation; and repeats the above process until the control system stabilizes. Ventricular pressure is monitored by the physiological feedback module and the cardiovascular coupling module, and personalized physiological characteristics analysis is performed in combination with the patient's body surface area, so that the pump speed parameters can be automatically optimized according to the patient's real-time physiological state.

This document describes systems and methods for cardiac monitoring and treatment using left atrial pressure. In many ways, an implantable pressure sensor in the patient's left atrium records a pressure signal. This left atrial pressure allows the calculation of the atrioventricular ratio (AVR), which is clinically relevant and can be used to guide treatment or as part of an open- or closed-loop automated treatment system.

Disclosed herein are devices and methods for addressing elevated left-sided filling pressures to mitigate the effects of diastolic dysfunction. The disclosed technologies decrease the temporal increase in blood flow and pressure into the heart from the venous system (which drains from the body). Under exertion, there is a shift of blood from the 'unstressed' reservoir of vasculature to the 'stressed' reservoir. By inhibiting this acute shift of blood from the unstressed reservoir to the stressed reservoir, an undesirable influx of blood volume to the already overloaded left heart can be avoided. Certain embodiments provide ways to maintain or to increase atrial elasticity, or atrial compliance using devices implanted in the left atrium and / or left atrial appendage. This increase or enhancement of atrial compliance enables the atrium to absorb the energy of short bursts of high left atrial pressure.

A method and devices for relieving pressure in the left atrium of a patient's heart is disclosed. The method includes using an ablative catheter in a minimally invasive procedure to prepare an opening from the coronary sinus into a left atrium of the patient's heart. Once the opening is prepared, the opening may be enlarged by a technique such as expanding a balloon within the opening. A stent is then placed within the coronary sinus of the patient, with a transverse portion expanding within the opening, allowing blood to flow from the left atrium to the coronary sinus and then to the right atrium. Pressure within the left atrium is thus relieved.

A left atrium pressure monitoring device based on an acoustic resonant cavity comprises an implant, a receiving probe and a host. The implant comprises a pressure film, a reflection cavity, a modulation structure and a shell, and is implanted into the left atrium through minimally invasive surgery; the pressure film is of a polyimide and silica gel composite structure and is used for sensing pressure and generating deformation; the reflection cavity is of a micro-cavity structure and is coupled with the pressure film; the modulation structure is arranged in the reflection cavity and is used for modulating reflected ultrasonic waves; the receiving probe transmits ultrasonic waves to the implant and receives modulated echoes; and the host processes the echo signal and displays a pressure value. According to the invention, lead-free and passive continuous monitoring is realized, and the device has the advantages of small implantation trauma, high measurement precision and good biocompatibility.

Disclosed herein are technologies for addressing elevated left-sided filling pressures to mitigate the effects of diastolic dysfunction. Embodiments provide ways to decrease the temporal increase in blood flow and pressure into the heart from the venous system. Under exertion, there is a shift of blood from the 'unstressed' reservoir of vasculature, which primarily comprises the splanchnic system, to the 'stressed' reservoir, which comprises the heart and lungs. By inhibiting this acute shifting of blood from the 'unstressed' reservoir to the 'stressed' reservoir, an undesirable influx of blood volume to the already overloaded left heart can be avoided. Certain embodiments provide ways to increase atrial elasticity, or atrial compliance. This enhancement of atrial compliance enables the atrium to 'absorb' the energy of short bursts of high left atrial pressure. Consequences are a reduction in the retrograde flow in the pulmonary veins to inhibit acute pulmonary congestion.

Systems for monitoring left atrial pressure using implantable cardiac monitoring devices and, more specifically, to a left atrial pressure sensor implanted through a septal wall are presented herein.

The present teaching provides devices and methods for treating heart disease by normalizing elevated blood pressure in the left and right atria of a heart. Various embodiments of the devices allow left-to-right blood flow through their flow elements. The flow element of the device is designed to self-adjust the amount of blood flow in response to the left atrial pressure fluctuation.

The application discloses a shunt, comprising a tube body, comprising an outer skeleton and an inner skeleton connected, a first through hole is formed on the outer skeleton, the first through hole is arranged along the axial direction of the outer skeleton, the inner skeleton is located on the inner side of the first through hole, the outer wall of the inner skeleton is at least partially spaced from the inner wall of the first through hole, a second through hole is formed on the inner skeleton, and the second through hole is arranged along the axial direction of the inner skeleton. Thus, by spacing the outer wall of the inner skeleton from the inner wall of the first through hole, a certain spacing distance is formed between the outer wall of the inner skeleton and the inner wall of the first through hole, so that a certain deformation space is formed between the inner skeleton and the inner wall of the first through hole. After the left atrial pressure of the patient increases, the inner skeleton can expand towards the radial outside under the pressure of the blood flow, so that the area of the radial section of the second through hole increases, the blood flow passing amount per unit area is increased, and the long-term increased blood flow pressure in the left atrium can be adapted.

The present disclosure relates to a device assembly and a method for treating heart failure by normalizing elevated blood pressure in the left atrium of a heart of a mammal. Disclosed herein is a RF energy-based transcatheter interatrial septum excision device configured to create a sized interatrial aperture between the right and left atria of a heart for the relief of elevated left atrial pressure. The device assembly comprises a delivery catheter, a tissue stabilizer attached to a tissue stabilizer catheter, a tissue cutter attached to a tissue cutter catheter, a remotely located RF generator connected to an RF cathode and anode of the device assembly.

The invention discloses a left atrium sensing implantation device based on piezoelectric ceramic ultrasonic energy supply and a sensing system. The left atrium sensing implantation device comprises a shell, piezoelectric ceramic, a sensor and a transceiving circuit. The piezoelectric ceramic adopts a partition electrode design, a concentric annular region of the piezoelectric ceramic is used for receiving in-vitro ultrasonic energy and converting the in-vitro ultrasonic energy into electric energy, and a fan-shaped region of the piezoelectric ceramic is used for modulating sensing data in a load keying (LSK) mode and backscattering the sensing data. The sensor is integrated based on a CMOS-MEMS process and synchronously collects pressure and temperature signals in the left atrium. The system further comprises an in-vitro ultrasonic probe and a host, and wireless energy supply, data return and information display are achieved. Complete wireless passive work and minimally invasive implantation of the implantation device are achieved, high-precision and continuous real-time monitoring of pressure and temperature of the left atrium is supported, and the device is suitable for long-term physiological parameter management of heart failure patients.

A medical system for monitoring a left atrial pressure in a heart of a patient may include an implantable device including an expandable framework and a first sensor secured to the expandable framework and an external component configured to communicate wirelessly with the implantable device. The first sensor may be configured to detect a first measurement. The first sensor may be a pressure sensor and the first measurement may be the left atrial pressure. The implantable device or the external component may include a processor configured to create a first trend for the first measurement. The processor may be configured to use the first trend to modify the first measurement prior to outputting a corrected result.

The utility model relates to a balloon type left atrium piezometric tube, which comprises a piezometric tube main body, the piezometric tube main body is a Y-shaped pipeline mainly formed by a main cavity piezometric tube, an auxiliary cavity balloon tube and an imbedding catheter, and the inner cavity of the main cavity piezometric tube and the inner cavity of the auxiliary cavity balloon tube are not communicated with each other. An eccentric balloon communicated with an inner cavity of the auxiliary cavity balloon tube is arranged at the front end of the auxiliary cavity balloon tube, and a sharp soft head is arranged at the front end of the imbedding catheter. Compared with a traditional left atrium piezometric tube, the balloon type left atrium piezometric tube is easier to operate, not prone to being separated from the left atrium, capable of stably and continuously measuring pressure and capable of being conveniently and rapidly pulled out.

The present disclosure relates to a device assembly and a method for treating heart failure by normalizing elevated blood pressure in the left atrium of a heart of a mammal. Disclosed herein is a transcatheter interatrial septum excision device assembly configured to create a sized interatrial aperture between the right and left atria of a heart for the relief of elevated left atrial pressure. The device assembly comprises a delivery catheter, a tissue stabilizer attached to a first catheter having a central lumen and a penetrating tip that permits passage of a guidewire, and a cutter attached to a second catheter having a central lumen that permits passage of the first catheter. Alternative configurations comprise a (third) catheter having a central lumen that permits passage of the aforementioned components to and from the right atrium, a tissue retention mechanism and an optional coaxial alignment mechanism.

A cardiac device configured to be positioned in a heart includes a body configured to be positioned in a wall between a right pulmonary vein and a right atrium or a superior vena cava and a sensor attached to the cardiac device. The sensor includes a sensor housing, a transducer, and control circuitry in the sensor housing in electrical communication with the transducer that is configured to sense a signal from a fluid in the right pulmonary vein, the right atrium, or the superior vena cava or a signal from the heart.

The present invention discloses a method for identifying the envelope of the mitral regurgitation spectrum and a method for measuring left atrial pressure, belonging to the field of curve correction technology. The method includes building a BCD-Unet deep learning model to complete the preliminary envelope of the Doppler spectrum curve; then post-processing the BCD-Unet deep learning model, designing a curve correction module to deal with the problem of curve misalignment, and designing a curve filling module to deal with the problem of curve breakage caused by the failure of some curves to be detected. In order to better integrate the information generated by the filling curve and the correction curve, a curve fusion module is also designed to further fuse the features of the two curves, combine the advantages of the two curves and obtain the final edge curve to meet the requirements of accurate measurement; iteratively train the model using data collected by the hospital, thereby continuously optimizing the model. The trained deep learning model has the ability to automatically track the envelope.

The present technology generally relates to a sensor assembly for an implantable medical device. In some embodiments, the sensor assembly includes a housing, a sensor, and a slip membrane. The sensor can be positioned at least partially inside the housing, and can be configured to measure one or more physiological parameters of a patient. For example, the sensor can be configured to measure a left atrial pressure and / or a right atrial pressure of the patient. The slip membrane can at least partially enclose the housing and the sensor. The slip membrane can be configured to protect the housing without adhering and / or sticking to an outer surface of the housing. In some embodiments, the slip membrane is composed of ePTFE. The slip membrane is also expected to reduce noise in and / or attenuation of signals received by the sensor.

Disclosed herein are technologies for addressing elevated left-sided filling pressures to mitigate the effects of diastolic dysfunction. Embodiments provide ways to decrease the temporal increase in blood flow and pressure into the heart from the venous system. Under exertion, there is a shift of blood from the 'unstressed' reservoir of vasculature, which primarily comprises the splanchnic system, to the 'stressed' reservoir, which comprises the heart and lungs. By inhibiting this acute shifting of blood from the 'unstressed' reservoir to the 'stressed' reservoir, an undesirable influx of blood volume to the already overloaded left heart can be avoided. Certain embodiments provide ways to increase atrial elasticity, or atrial compliance. This enhancement of atrial compliance enables the atrium to 'absorb' the energy of short bursts of high left atrial pressure. Consequences are a reduction in the retrograde flow in the pulmonary veins to inhibit acute pulmonary congestion.

Apparatus, systems, and methods are provided for an implantable cardiac device designed for placement within or near the left atrial appendage (LAA) of a heart, configured to estimate left atrial pressure (LAP) or changes therein by detecting mechanical changes associated with variations in LAP. The device comprises a cap integrated with one or more mechanical sensors-such as strain gauges, piezoelectric elements, or accelerometers-that detect mechanical deformations corresponding to LAP fluctuations. A processor receives data from these sensors and estimates LAP based on the detected mechanical changes. The device may also include an electrical sensor to measure an electrocardiogram (ECG) signal, allowing the processor to estimate changes in LAP by comparing time delays between the ECG signal and mechanical signals.