17 results about "Aortic pressure" patented technology

Aspects of the present disclosure describe systems and methods for predicting an intra-aortic pressure of a patient receiving hemodynamic support from a transvalvular micro-axial heart pump. In some implementations, an intra-aortic pressure time series is derived from measurements of a pressure sensor of the transvalvular micro-axial heart pump and a motor speed time series is derived from a measured back electromotive force of a motor of the transvalvular micro-axial heart pump. Furthermore, in some implementations, machine learning algorithms, such as deep learning, are applied to the intra-aortic pressure and motor speed time series to accurately predict an intra-aortic pressure of the patient. In some implementations, the prediction is short-term (e.g., approximately 5 minutes in advance).

Apparatus and methods are described including implanting an aortic pressure-loss-reduction device in a subject's ascending aorta. A frame of the device includes a first set of sinusoidal struts disposed between a downstream end of an upstream anchor and an upstream end of the intermediate portion, the sinusoidal struts being shaped to form a folded portion between the downstream end of the upstream anchor and the upstream end of the intermediate portion. The frame includes a second set of sinusoidal struts disposed between an upstream end of a downstream anchor and a downstream end of the intermediate portion, the sinusoidal struts being shaped to form a folded portion between the upstream end of the downstream anchor and the downstream end of the intermediate portion. Other applications are also described.

The invention provides a self-adaptive control method and device for a double-ventricle auxiliary system. The method comprises the steps that target aortic pressure detected by a first pressure sensor, target left ventricular end diastolic pressure detected by a second pressure sensor, target right atrial pressure detected by a third pressure sensor and target pulmonary artery pressure detected by a fourth pressure sensor are obtained; and determining a strategy for adjusting the left ventricular assist device or the right ventricular assist device according to the target left ventricular end diastolic pressure, the target right ventricular pressure and the target pulmonary arterial pressure when the peripheral perfusion of the target user is insufficient or the lung is over-perfused. The pressure sensors are arranged to detect the pressure of the inlets and the outlets of the left ventricular assist device and the right ventricular assist device, whether adverse events such as peripheral insufficiency or pulmonary hyperperfusion occur to a user or not is judged according to the detected pressure, and then the adverse events are relieved or even solved by adjusting the rotating speeds of the left ventricular assist device and the right ventricular assist device. And the safety of the user is greatly improved.

The invention provides a ventricular elasticity value estimation method and device.The method comprises the steps that a first parameter and a second parameter are obtained, the first parameter comprises at least one of target ventricular pressure, target aortic pressure and target pulmonary arterial pressure of a target user, and the second parameter comprises at least one of the target ventricular pressure, the target aortic pressure and the target pulmonary arterial pressure; the second parameter comprises the pumping flow of the target ventricular assist device and the cardiac cycle of the target user; inputting the first parameter and the second parameter into a target decision model, and outputting a target ventricular volume; and estimating a target ventricular elasticity value according to the ratio of the target ventricular pressure to the target ventricular volume. The ventricular volume of the current user is estimated through the decision model, the estimated ventricular elasticity value is calculated according to the ratio of the ventricular pressure to the ventricular volume, and the ventricular elasticity value of the patient can be accurately predicted in real time without depending on ultrasonic equipment.

The invention relates to the technical field of medical instruments, and particularly discloses a catheter handle, a catheter pump and a catheter pump system. According to the catheter handle, the perfusion liquid inflow connector, the artery pressure measuring liquid inlet connector, the artery pressure measuring liquid outlet connector and the catheter connector are arranged on the perfusion support, the perfusion liquid outflow connector is arranged on the coupling support, the perfusion support and the coupling support are large in size, and therefore the connectors can be conveniently arranged; the number of parts is reduced, so that the machining process of the guide pipe device is simplified; besides, the artery pressure measuring liquid inlet connector and the artery pressure measuring liquid outlet connector are arranged on the perfusion stent, the connectors can be conveniently arranged, an independent aorta pressure sensing channel is formed, and compared with the prior art, flowing of perfusion liquid used for sensing the aorta pressure is not prone to being interfered by other factors, and the perfusate can be used for sensing the aorta pressure. And thus, the aortic pressure sensing precision is improved.

Apparatus and methods are described including an aortic pressure-loss-reduction device (20) configured to be delivered to and implanted inside an ascending aorta of a subject using a delivery device. The aortic pressure-loss-reduction device (20) includes a frame and a layer of material (54) coupled to at least a portion of the frame, the material layer configured to impede blood flow therethrough. A retrieval element (240), configured to facilitate retrieval of the aortic pressure-loss-reduction device (20) from the ascending aorta back into the delivery device, is coupled to an outside of the aortic pressure-loss-reduction device (20) and is configured to be disposed externally to the aortic pressure-loss-reduction device (20).

Apparatus and methods are provided for use with a left-ventricular assist device (20) including a pump-outlet tube (24) configured for insertion, through an aorta of a subject, into a left ventricle of a heart of the subject such that a proximal section of the pump-outlet tube is disposed within the aorta and a distal section of the pump-outlet tube is disposed within the left ventricle. A pressure sensor (206) outputs a signal indicative of an aortic pressure within the aorta over an interval. A processor (25) compares an indication of the minimum of the aortic pressure to an indication of the peak-to-peak amplitude of the estimated pressure gradient between the aorta and the left ventricle over an interval, and, in response thereto, outputs an indication that the pump-outlet tube (24) is positionally biased toward the aorta. Other applications are also described.

The application discloses a double-gas-path air source system, a double-gas-path heart auxiliary system and a use method. The double-gas-path heart auxiliary system comprises a pressure generating mechanism, a first auxiliary device, a second auxiliary device, a detection device and a control mechanism. The pressure generating mechanism alternately generates positive pressure and negative pressure during work. The first auxiliary device comprises a first driven device and a first pipe line, and a tube body at the farthest end of the first pipe line is provided with an inflow and an outflow. The first driven device is located in the tube body of the first pipe line and corresponds to the position of the outflow. The second auxiliary device comprises a second driven device and a second pipe line in communication with the second driven device. The pressure generating mechanism makes the second driven device repeatedly expand and contract through the second pipe line. The detection device is used for acquiring the intraventricular pressure and the intra-aortic pressure. The control mechanism controls the pressure generating mechanism to drive the first driven device and the second driven device according to the corresponding time sequence in a cycle control period according to the pressure signal sent by the detection device.

The systems, devices, and methods presented herein use a blood pump to obtain measurements of cardiac function. The system can quantify the functioning of the native heart by measuring certain parameters / signals such as aortic pressure or motor current, then calculate and display one or more cardiac parameters and heart function parameters, such as left ventricular pressure, left ventricular end diastolic pressure, or cardiac power output. These parameters provide valuable information to a user regarding current cardiac function, as well as positioning and function of the blood pump. In some embodiments, the system can act as a diagnostic and therapeutic tool. Providing cardiac parameters in real-time, along with warnings about adverse effects and recommendations to support cardiac function, such as increasing or decreasing the volumetric flow rate of blood pumped by the device, administering pharmaceutical therapies, and / or repositioning the blood pump allow clinicians to better support and treat cardiovascular disease.

In order to solve the technical problem of poor stability of a catheter in vivo in the prior art, the utility model provides the extracorporeal circulation catheter with the sensor, the extracorporeal circulation catheter comprises an intracorporeal end head, the intracorporeal end head is provided with a drainage port along the catheter wall, and the sensor is arranged at the front end and / or the rear end of the drainage port. The sensor is additionally arranged near the drainage opening of the catheter to monitor the liquid pressure of the catheter in the environments where the catheter is located at different positions, and the aorta pressure waveform of a patient is combined, so that the position of the head of the inner end of the catheter can be judged, an operator can be conveniently guided to insert the catheter in place without monitoring, and the operation efficiency is improved. And in addition, the position of the extracorporeal circulation guide pipe and the flow and pressure conditions in the guide pipe can be monitored during the operation period of the extracorporeal centrifugal pump, so that the stability and safety of the guide pipe in the body are improved.

The invention relates to a method for monitoring cardiac cycle synchronized extracorporeal circulation support and to a corresponding device and circulation support device, in particular for optimizing the provided support pulses. Accordingly, a method for monitoring cardiac cycle synchronized extracorporeal circulation support (12) of a patient is described, comprising the steps of: receiving a pressure value characterizing an aortic pressure of the supported patient; determining a first minimum pressure value (40) of the cardiac cycle of the patient and a first point in time of the minimum pressure value (40) from the pressure values; determining, from the pressure value, whether there is a reduced rate of change of pressure at a subsequent second point in time (42), the reduced rate of change of pressure lying between an immediately preceding greater rate of change of pressure and a subsequent greater rate of change of pressure; and outputting a signal as a function of the reduced rate of pressure change (42) present. The pressure value is received by a pressure sensor (32) arranged upstream of an arterial cannula (30) of an extracorporeal circulation support (12) and downstream of an oxygenator (28).

Methods and apparatus for an auxiliary monitor including a communication interface and at least one computer processor are described. The communication interface is configured to receive first data from a first patient monitoring device and second data from a second patient monitoring device, the first patient monitoring device including a heart pump, and the first data including an aortic pressure signal and a ventricular pressure signal measured during operation of the heart pump. The at least one computer processor is programmed to detect a timing of heartbeats in the aortic pressure signal and / or the ventricular pressure signal, determine a pulse pressure of the aortic pressure signal and / or the ventricular pressure signal within time windows associated with the timing of heartbeats, compare the determined pulse pressure against one or more metrics to identify one or more events, and output on a user interface, an indication of the one or more events.

This invention discloses a pulsed blood pump thermal management control system based on speed modulation. The control system is configured to perform the following steps: generating an initial state vector based on historical key motor parameters, blood pump output flow rate, blood temperature, and aortic differential pressure; using a strategy network to output a speed adjustment vector based on the initial state vector, thereby controlling the motor speed; generating a current state vector based on the current key motor parameters, blood pump output flow rate, blood temperature, and aortic differential pressure, and calculating an immediate reward; updating the value network based on the state vectors at n time points and the immediate reward; and updating the strategy network based on the prediction reward error of the value network. This invention achieves temperature rise minimization under constraints such as blood pump output flow rate, blood temperature, and aortic differential pressure, ensuring that the blood pump provides stable blood flow support during long-term operation while effectively preventing adverse biological effects.

The invention provides a ventricular assist device and a control unit thereof, the control unit obtains a target current curve and a target pressure curve, the target current curve is a current curve of the ventricular assist device in a first period, and the target pressure curve is an aortic pressure curve of the ventricular assist device in the first period; calculating a plurality of target features according to the target current curve and the target pressure curve; and when the plurality of target features meet a preset requirement, determining that the position of the ventricular assist device is abnormal. According to the method, the multiple target features capable of evaluating the abnormal position of the ventricular assist device are calculated through the current curve and the pressure curve of the ventricular assist device, whether the position of the ventricular assist device is abnormal or not is determined according to the sizes of the multiple target features, real-time detection of the position of the ventricular assist device can be achieved, and the safety of a patient is guaranteed.

Apparatus and methods are provided for use with a left-ventricular assist device (20) including a pump-outlet tube (24) configured for insertion, through an aorta of a subject, into a left ventricle of a heart of the subject such that a proximal section of the pump-outlet tube is disposed within the aorta and a distal section of the pump-outlet tube is disposed within the left ventricle. A pressure sensor (206) outputs a signal indicative of an aortic pressure within the aorta over an interval. A processor (25) compares an indication of the minimum of the aortic pressure to an indication of the peak-to-peak amplitude of the estimated pressure gradient between the aorta and the left ventricle over an interval, and, in response thereto, outputs an indication that the pump-outlet tube (24) is positionally biased toward the aorta. Other applications are also described.

Apparatus and methods are described including an aortic pressure-loss-reduction device (20) configured to be implanted inside an ascending aorta of a subject. The aortic pressure-loss-reduction device includes a frame (52) that defines an upstream anchor portion (33F), an intermediate portion (23F) configured to define a conduit (26) therethrough, and a downstream anchor portion (31F). Angled struts (150) are disposed between a downstream end of the upstream anchor portion (33F) and an upstream end of the intermediate portion (23F). The angled struts (150) are configured such that, in response to a diameter of the upstream anchor portion (33F) changing by an absolute amount, an absolute change in a diameter of the upstream end of the intermediate portion (23F) is less than the absolute amount by which the diameter of the upstream anchor portion (33F) changes. Other applications are also described.

The systems, devices, and methods presented herein use a blood pump to obtain measurements of cardiac function. The system can quantify the operation of the natural heart by measuring certain parameters / signals (such as aortic pressure or motor current), and then calculate and display one or more cardiac parameters and cardiac function parameters (such as left ventricular pressure, left ventricular end-diastolic pressure, or cardiac power output). These parameters provide the user with valuable information about current cardiac function and the positioning and function of the blood pump. In some embodiments, the system can serve as a diagnostic and therapeutic tool. Providing cardiac parameters in real time together with warnings about adverse effects and recommendations to support cardiac function (such as increasing or decreasing the volume flow rate of blood pumped by the device), administering medication, and / or repositioning the blood pump allows clinicians to better support and treat cardiovascular disease.