29 results about "Ascending aorta" patented technology

A prosthesis assembly includes a stent frame that is expandable and configured for being positioned in the ascending aorta, and a receiving socket positioned within a proximal end of the prosthesis assembly. The receiving socket defines a recess for allowing flowthrough of blood into the stent frame. The receiving socket is further configured for selectively receiving a heart valve assembly for replacing a native heart of a patient or maintaining a mode of operation where the socket is empty and blood flows through the socket into the stent frame.

Apparatus and methods are described including implanting an aortic pressure-loss-reduction device in a subject's ascending aorta. A frame of the device includes a first set of sinusoidal struts disposed between a downstream end of an upstream anchor and an upstream end of the intermediate portion, the sinusoidal struts being shaped to form a folded portion between the downstream end of the upstream anchor and the upstream end of the intermediate portion. The frame includes a second set of sinusoidal struts disposed between an upstream end of a downstream anchor and a downstream end of the intermediate portion, the sinusoidal struts being shaped to form a folded portion between the upstream end of the downstream anchor and the downstream end of the intermediate portion. Other applications are also described.

The subject of the invention is a delivery system for delivering a self-expanding endoluminal prosthesis to the patient's ascending aorta and aortic valve, the system comprising: - an inner tube (33), extending along a longitudinal Y axis of the delivery system (100), from an atraumatic distal tip (27) to a handle (37); - a metal tube (32), slide-fitted on the inner tube (33), and extending from the internal space of the distal tip (27) to a handle (37); - an outer tubular catheter shaft (22) slide-fitted on the metal tube (32), the catheter shaft (22) is brought out from the handle (37) and is terminated by a capsule (20), containing inside the radially compressed on the metal tube (32), self-expanding endoluminal prosthesis (1) having defined construction and covered at least partially by a coating (16), - the capsule (20) has closed position when is closed by the tip (27) and has open position when the capsule (20) and the tip (27) are displaced relative to each other; wherein the distal part of the metal tube (32) is equipped with receiving means (41, 42) on which the distal locking means (7) of prosthesis (1) are removably embedded and blocked in the inner space of the tip (27) and the delivery system (100) comprises also removable holding means (45, 45') retaining the proximal locking means (9) of the prosthesis (1), so that when the capsule (20) is in its fully open position, the prosthesis (1) is still maintained partially compressed, holding its crimping length.

Described herein are pumps that linearly reciprocate to assist with circulating blood within the body of a patient. Red blood cell damage may be avoided or minimized by such linear pump movement. The linearly reciprocating movement may also generate a pulsatile pumping cycle that mimics the natural pumping cycle of the heart. The pumps may be configured to reside at various body locations. For example, the pumps may be situated within the right ventricle, the left ventricle, the ascending aorta, the descending aorta, the thoracic aorta, or the abdominal aorta. In some instances, the pump may be deployed within the venous circulation. In other instances, the pump may reside outside the patient.

The application provides an interventional ventricular auxiliary oxygen generation device, a blood flow channel crosses an aortic valve into a left ventricle from an ascending aorta, a blood inlet of the blood flow channel is located in the left ventricle, a blood outlet is located in the ascending aorta, a first conveying pipe and a second conveying pipe convey hydrogen peroxide and catalase into the left ventricle to generate oxygen and water through reaction, and a pumping unit pumps oxygen-rich blood in the left ventricle to the ascending aorta. The oxygen generation function is added to the ventricular auxiliary device, the oxygen-rich blood in the ventricle is pumped to the ascending aorta through the ventricular auxiliary device, which directly improves the myocardial hypoxia condition and helps the heart recover, and on the other hand, the oxygen-rich blood is pumped into the ascending aorta and directly participates in the systemic circulation, thereby directly and quickly improving the oxygen supply condition of the systemic circulation.

Apparatus and methods are described including an aortic pressure-loss-reduction device (20) configured to be delivered to and implanted inside an ascending aorta of a subject using a delivery device. The aortic pressure-loss-reduction device (20) includes a frame and a layer of material (54) coupled to at least a portion of the frame, the material layer configured to impede blood flow therethrough. A retrieval element (240), configured to facilitate retrieval of the aortic pressure-loss-reduction device (20) from the ascending aorta back into the delivery device, is coupled to an outside of the aortic pressure-loss-reduction device (20) and is configured to be disposed externally to the aortic pressure-loss-reduction device (20).

Provided is a cannula capable of safely and effectively supplying blood in an antegrade manner from the ascending aorta while having a smaller diameter. The cannula comprises an antegrade blood return tube 1 and a blood supply tube 4. The antegrade blood return tube 1 has a distal end part having a guide wire opening that extends in the longitudinal direction substantially along the central axis of the distal end part. A guide wire tube 5 is placed through the opening. A guide wire 50 is inserted through the guide wire tube 5. The antegrade blood return tube 1 comprises a distal tapered portion on the distal side and a body portion on the proximal side, and the distal tapered portion and the body portion are integrally molded. The distal tapered portion comprises a tip part and fins, and the body portion comprises fins and a tubular part. The proximal end of the tip part, the fins, and the distal end of the tubular part forms a louver 2. The louver 2 is supported by a total of four beams extending from the tip part to the tubular part in the longitudinal direction of the antegrade blood return tube 1.

The application aims to provide a blood circulation assisting system capable of generating pulsating blood flow and guaranteeing body functions, comprising a first blood circulation supporting unit located in a heart chamber of a patient and a second blood circulation supporting unit located in a descending aorta of the patient, the first blood circulation supporting unit pumping blood in the heart chamber to the aorta, and the second blood circulation supporting unit generating pulsating blood flow by periodically contracting and expanding to squeeze blood, and partially blocking the blood vessel when expanding. When the second blood circulation supporting unit periodically expands to squeeze blood, it does not completely block the blood vessel, but leaves a part of the blood flow passage, so as to allow part of the blood to pass through, prevent the ascending aorta pressure from suddenly rising, and prevent the blood from flowing back to the left ventricle, and also prevent the second blood circulation supporting unit from moving, so as to guarantee the pulsating effect and prevent unnecessary damage to the inner wall of the blood vessel.

The invention relates to a left ventricle auxiliary device and an implantation assembly. The left ventricle auxiliary device comprises a small and special electric machine and a housing with a blood channel, the small and special motor comprises a shell and a pump machine body, the pump machine body is provided with a motor shaft, pump blades are arranged on the motor shaft, and the motor shaft extends out of the shell and extends into the housing; the shell is provided with a rear cover, the inner end of the wire penetrates through the rear cover to be electrically connected with the pump machine body, and the outer end of the wire is electrically connected with an external power supply control device. The housing comprises a pumping-in cover, a transition pipe and a pumping-out cover, the pumping-in cover is provided with a blood suction hole, and the pumping-out cover is provided with a blood discharge hole; a first suction cup and a second suction cup are arranged outside the shell, and a third suction cup and a fourth suction cup are arranged outside the transition pipe. The left ventricle auxiliary device can be implanted into a body through the implantation assembly. The left ventricle auxiliary device is simple and small in structure, implantation can be completed through percutaneous puncture by means of the implantation assembly, blood can be pumped into the ascending aorta from the left atrium through a blood channel, and the left ventricle auxiliary function is achieved.

The invention discloses an ascending aorta full-cavity integrated branch covered stent system. The stent system comprises a main stent and a branch stent, wherein the main stent is sequentially provided with an ascending aorta far-end anchoring sealing area, an accordion type elastic stent area, an ascending aorta near-end anchoring sealing area, a coronary artery branch reconstruction area, a flexible buffer area and an artificial aortic valve area; the ascending aorta far-end anchoring sealing area, the accordion type elastic support area, the ascending aorta near-end anchoring sealing area, the coronary artery branch reconstruction area and the flexible buffer area are provided with annular metal frames, the outer portions of the metal frames are coated with covering films by attaching to the metal frames, and the axis of each annular metal frame is the same as that of the main body support. According to the invention, the problem that the implanted ascending aorta stent affects the physiological function of the heart in the prior art is solved.

A method of performing a post-TAVR PCI procedure includes providing a catheter device including a housing, an outer tubular member coupled to the housing, an inner tubular member slidably received within an interior of the outer tubular member, and a slider coupled to the housing and the inner tubular member, wherein the inner tubular member is configured to slide relative to the outer tubular member. The outer tubular member is advanced into an interior of a TAVR valve disposed in an ascending aorta of a patient and a guidewire is extended from the outer tubular member to cause the guidewire to enter a coronary artery branching from the ascending aorta. The inner tubular member is extended from the outer tubular member into the coronary artery via a sliding of the slider relative to the housing, and the outer tubular member is optionally advanced further over the inner tubular member.

Described herein are pumps that linearly reciprocate to assist with circulating blood within the body of a patient. Red blood cell damage may be avoided or minimized by such linear pump movement. The linearly reciprocating movement may also generate a pulsatile pumping cycle that mimics the natural pumping cycle of the heart. The pumps may be configured to reside at various body locations. For example, the pumps may be situated within the right ventricle, the left ventricle, the ascending aorta, the descending aorta, the thoracic aorta, or the abdominal aorta. In some instances, the pump may be deployed within the venous circulation. In other instances, the pump may reside outside the patient.

The application relates to an aortic stent and a manufacturing method thereof. The manufacturing method of the aortic stent comprises the following steps: providing a proximal stent section for being implanted into a descending aorta, a distal stent section for being implanted into an ascending aorta, and an arch stent section for being implanted into an aortic arch; providing a foldable covering film; covering the covering film on the proximal stent section and the distal stent section; providing a keel line with a pre-bent shape; and penetrating the keel line through the proximal stent section, the arch stent section and the distal stent section; wherein the proximal stent section, the arch stent section and the distal stent section jointly define a supporting cavity, the covering film is foldable, and the keel line has the pre-bent shape. The whole stent can be bent along the bending direction of the keel line, so that the elastic straightening force of the aortic stent itself can be reduced, the flexibility of the aortic stent is improved, and the complications caused by poor adhesion are reduced.

The present application relates to cardiovascular disease medical equipment technical field, disclose a kind of aortic covered stent, the aortic covered stent includes support stent, closure layer and elastic connecting layer, closure layer is spaced apart and is set to the outer periphery of support stent, closure layer includes first covering, elastic connecting layer is connected between support stent and closure layer, blood flow can flow between support stent and closure layer;With aortic pulsation, closure layer and elastic connecting layer produce elastic deformation, so that first covering is always close to aortic and the blood vessel wall adjacent to closure layer.The aortic covered stent can be better applied to the special form of ascending aortic dissection and the mechanical characteristics of blood flow, higher stability, better closure for ascending aortic wall.

A device for protecting debris from entering coronary arteries, the device including an expandable frame, and a debris blocking obstacle, wherein the expandable frame is shaped and sized to expand against walls of an ascending aorta. A method of reducing damage to the heart during a vascular procedure including identifying a potentially debris-causing event, and reducing debris carried by backflow from an aorta into a coronary artery during diastole in response to the identifying. A method for protecting debris from entering coronary arteries during a medical procedure, the method including inserting a device for protecting debris from entering coronary arteries into an aorta of a patient, positioning the device to protect debris from entering the coronary arteries, and performing the medical procedure on a heart of the patient. Related apparatus and methods are also described.

The application is a catheter pump with oxygen supply function which can improve oxygen supply of body circulation, the proximal end of the motor is connected with the catheter, the distal end is coaxially connected with an impeller, the outer periphery cover of the impeller is provided with a blood outflow cage, the distal end of the blood outflow cage is fixed with the proximal end of a blood inflow cage through a sleeve, the distal end of the blood inflow cage is further connected with a pigtail tube, an oxygen supply unit is arranged on the blood outflow cage, the oxygen supply unit generates oxygen according to physiological signals collected by a sensing unit in the ascending aorta according to time and demand, and releases the oxygen into the blood in the ascending aorta. In the process of assisting the heart to pump blood, the catheter pump can simultaneously supplement oxygen into the blood by using the oxygen supply unit, and improve the hypoxia condition of the whole body tissue. The oxygen supply unit is integrated on the catheter pump, and the catheter pump is intervened through the blood vessel together with the oxygen supply unit, so that the operation is simple, the damage to the blood vessel is reduced, the risk of gas embolism is reduced, the oxygen is better distributed, the oxygen supply mode is more in line with the physiological state, and the recovery of the patient is facilitated.

The invention discloses a valved endovascular graft for Endo-Bentall, which relates to the technical field of medical instruments and comprises an ascending aorta graft and two coronary artery covered stents. The ascending main section is a straight tube type covered stent, the far end of the ascending main section is anchored to the ascending aorta, and the near end of the ascending main section is provided with an embedded branch opening in the sinus tube section; the sinus canal section is in a concave shape and is provided with a metal bare stent and an embedded branch opening for bridging the coronary artery; a biological valve is sewn in the sinus valve section, and the far end of the sinus valve section is anchored to the left ventricular outflow tract. The anchoring area sequentially comprises a left ventricular outflow tract, a sinus tube junction and an ascending aorta. The coronary artery branch covered stent is conical and small-caliber, the near end is connected with the embedded branch, and the far end extends into the coronary artery. The graft can be used for repairing dissection lesions and reconstructing coronary artery and aortic valves in the whole cavity.

The present application provides a catheter simulator capable of improving catheter operation technology for brain diseases through a simple structure. The catheter simulator is characterized by having: a container (10); a cerebral vessel model (100) held in the container in a state of containing a liquid; and a holding unit provided to a side wall of the container and the cerebral vessel model and holding the cerebral vessel model in the container in a state of being filled with the liquid. The holding unit has: a first holding portion (21) that holds an end portion of an ascending aorta (101a) of the cerebral vessel model; and a second holding portion (22) that holds an end portion of a descending aorta (101b) of the cerebral vessel model, the first holding portion (21) has a liquid introduction port that introduces the liquid into the cerebral vessel model, the second holding portion (22) has a catheter introduction port that introduces a catheter into the cerebral vessel model, and an opening portion (121, 122) that controls balance of the liquid circulating in the cerebral vessel model is formed in a casing (100A) constituting the cerebral vessel model.

The invention discloses an on-site installation type full endoluminal repair system for treating Stanford A-type dissection. The on-site installation type full endoluminal repair system comprises an ascending aorta stent-type blood vessel (ascending main assembly), a coronary artery branch covered stent-type blood vessel (coronary artery assembly) and a self-expanding aorta interventional valve (valve assembly) capable of being installed on site according to needs. The lifting main assembly is divided into a lifting main section and a sinus tube section, the lifting main section is a covered stent, the head end is anchored to an ascending aorta, the tail end is transited to be a concave sinus tube section, embedded branches are arranged at the two ends in a cavity of the covered stent in front of the concave part, openings are formed in the sinus tube section, and a metal bare stent is arranged outside the sinus tube section. The coronary artery branch covered stent is a conical small-caliber covered stent, the near end of the coronary artery branch covered stent is connected with an embedded branch of the lifting main assembly, and the caliber of the far end varies due to left and right coronary arteries. The graft may engage the aortic valve component as desired. The invention is specially used for treating the Stanford A-type dissection lesion of the aorta root, can repair the aortic lesion, reconstruct the bilateral coronary artery and connect the aortic valve as required, and can be produced in batches for emergency operations.

The application relates to a ventricular pressure regulating device and a control method thereof. The ventricular pressure regulating device comprises: a balloon assembly, the balloon assembly comprising a balloon and a bandage, the bandage being used for fixing the balloon outside the ascending aorta, and the balloon being connected with an air pipe; a gas filling pump and a gas pumping pump, the gas filling pump being communicated with a gas filling tank, the gas pumping pump being communicated with a gas pumping tank, and the gas filling tank and the gas pumping tank being connected to the air pipe; and a control device, the control device being connected to the gas filling pump and the gas pumping pump, and being used for controlling the gas filling pump and the gas pumping pump to regulate the air pressure in the balloon. The application can greatly reduce the infection risk; the control device can control the gas filling pump and the gas pumping pump to regulate the air pressure in the balloon, the precision is better, and discomfort is not easily caused; and the gas filling tank and the gas pumping tank can buffer the gas filling and gas pumping, so that the gas filling pump and the gas pumping pump do not need to work all the time, and the technical problems of the high infection risk and the easy causing of discomfort in the related art are solved.

Provided is a cannula with which it is possible to effectively and antegradely send blood from the ascending aorta, while reducing the diameter. This cannula, in which the distal end part thereof is disposed in the ascending aorta and blood fed from an external-membrane-type artificial lung is sent antegradely from the ascending aorta, comprises an antegrade blood return part 2 and a blood-sending tube 4, the antegrade blood return part 2 being provided at the distal end of the blood-sending tube 4. A guide wire tube 5 extending in the longitudinal direction from the base end part to the distal end part is disposed substantially at the center of the axis inside the antegrade blood-sending cannula 1. The blood-sending tube 4 is a tube provided on the base end side connected to the extracorporeal-membrane-type artificial lung.

A minimally invasive, small percutaneous mechanical circulatory support system delivers a pump transcatheterally to the heart, which actively reduces the burden on the left ventricular system by pumping blood from the left ventricle to the ascending aorta and then to the systemic circulation. The pump may include a tubular housing, a motor, an impeller configured to be rotated by the motor, and a distal tip of the pump. The tip may include a guidewire lumen having a curved and / or extended contour. The system may include an insertion tool having a tubular body and configured to receive the circulatory support device axially movable, and an introducer sheath configured to receive the insertion tool axially movable. A coupling allows for connection and disconnection between the insertion tool and the introducer sheath. The coupling may include a hexagonal portion for self-positioning and further for tactile feedback.

The present disclosure provides a solution for assisting cardiac circulation of a subject. In one aspect of the present disclosure, the new solution replaces the common practice of implementing a cannula of left ventricular assist device (LVAD) to the left ventricle (LV) through a large opening made in the apex of the LV, which has some disadvantages such as requirement of sternotomy, making a hole in an already very weak left ventricle, requirement of cardiopulmonary bypass, etc.The solution of the present disclosure suggests introducing the inflow cannula, namely the cannula / tube that suctions blood from the heart, through an opening made in the left atrium appendage (LAA) and guiding it through the left atrium (LA) and the mitral valve (MV) into the LV to be positioned therein. The inflow cannula is designed to allow suction of blood along various portions of its length that are intended to be positioned within the heart, namely along portions that are positioned in the LV, LA and optionally the LAA.The blood that is suctioned by the inflow cannula flows into a mechanical circulatory support device to be pumped therefrom, via an outflow cannula and into the aorta, thereby allowing supply of oxygenated blood to the entire body. Optionally, the outflow cannula can be coupled to the descending aorta and not to the ascending aorta as commonly done in the cases of LVAD implementations.A second aspect of the present disclosure provides a new solution for overcoming right ventricle failure by withdrawing blood from a first portion of the pulmonary artery and streaming blood to a second portion of the pulmonary artery, the second portion is downstream the first portion, namely more proximal to the lungs. The two solutions may be carried out by a similar surgical procedure, such as left thoracotomy. If the two solutions of the present disclosure are used together, they form a total artificial heart solution.

The techniques of this disclosure generally relate to modular stent device and method of deploying the same. The method includes introducing a delivery system including the modular stent device via supra aortic access. The delivery system is advanced into the ascending aorta. Once positioned, the modular stent device is deployed from the delivery system such that an artery leg of the modular stent device engages the brachiocephalic artery and a bypass gate engages the aorta, wherein the artery leg partially collapses the bypass gate. The artery leg has a greater radial force than the bypass gate such that the artery leg remains un-collapsed and opened. Accordingly, blood flow through the artery leg and perfusion of the brachiocephalic artery and preservation of blood flow to cerebral territories including the brain is insured.

This invention relates to a tool for measuring the rotation angle of an aortic endovascular stent graft, belonging to the field of medical device technology. It includes a first column, a second column, a base, a circular track, and a measuring column. A circular track is provided along the horizontal plane on the base, and a movable first column, perpendicular to the horizontal plane, is positioned on the circular track. A second column, perpendicular to the horizontal plane, is located at the center of a virtual circle containing the circular track. A measuring column is located on the upper surface of the first column, and the central axis of the measuring column intersects perpendicularly with the central axis of the second column. This invention can simulate real-world stent usage scenarios, simulating the connection between the ascending and descending aorta, and accurately measuring the angle of deviation of the marker after bending under stent graft bending conditions, directly obtaining the true bending deviation of the stent. The testing device has a simple structure, is convenient and quick to use, has high simulation accuracy, and provides stable and reliable test results.

The invention belongs to the technical field of medical instruments, and particularly relates to an ascending aorta covered stent with biomechanical property, which comprises a support skeleton, the inner side and the outer side of the support skeleton are both covered with films, the support skeleton is formed by spirally winding functional metal wires, the functional metal wires are formed by spirally winding composite wires, and the functional metal wires are wound by the composite wires. And the composite filament is formed by weaving a plurality of strands of filaments. In terms of overall performance, the large vessel covered stent can be highly synchronized with radial expansion / retraction, circumferential stretching, longitudinal displacement and slight torsion generated by the ascending aorta in the cardiac contraction and diastole period, and therefore natural physiological movement of the aorta is effectively simulated.

This disclosure generally relates to a modular stent device comprising a main body configured to deploy in the ascending aorta, a bypass valve configured to deploy in the aorta, and a bifurcated contralateral branch. The bifurcated contralateral branch includes a single proximal branch that bifurcates (diversifies) into a first distal branch and a second distal branch. By forming the bifurcated contralateral branch as a single proximal branch that bifurcates into the distal branch, guiding a guide wire proximally into the relatively larger opening of the bifurcated contralateral branch is simpler than guiding a guide wire into two smaller branches extending distally from the main body. Therefore, cannulation of the bifurcated contralateral branch is relatively simple, thus simplifying the procedure. Furthermore, the parallel design mimics anatomical vascular bifurcation to limit flow interruption.

Apparatus and methods are described including an aortic pressure-loss-reduction device (20) configured to be implanted inside an ascending aorta of a subject. The aortic pressure-loss-reduction device includes a frame (52) that defines an upstream anchor portion (33F), an intermediate portion (23F) configured to define a conduit (26) therethrough, and a downstream anchor portion (31F). Angled struts (150) are disposed between a downstream end of the upstream anchor portion (33F) and an upstream end of the intermediate portion (23F). The angled struts (150) are configured such that, in response to a diameter of the upstream anchor portion (33F) changing by an absolute amount, an absolute change in a diameter of the upstream end of the intermediate portion (23F) is less than the absolute amount by which the diameter of the upstream anchor portion (33F) changes. Other applications are also described.

This invention relates to a method and apparatus for processing characteristic dimensions based on cardiac ultrasound video measurements. The method includes: receiving a first video; extracting video frame images; detecting key points in each frame image based on a key point detection model; filtering diastolic and systolic frame images; filtering mid-systolic ventricular frame images; annotating key points and characteristic dimensions of the right ventricular diameter, interventricular septum thickness, left ventricular diameter, and left ventricular posterior wall thickness on the diastolic frame images; annotating key points and characteristic dimensions of the left ventricular diameter on the systolic frame images; annotating key points and characteristic dimensions of the left atrial anteroposterior diameter, aortic valve annulus diameter, aortic sinus diameter, and ascending aortic diameter on the mid-systolic ventricular frame images; and outputting the annotated diastolic, systolic, and mid-systolic ventricular frame images as the processing result. This invention can solve the problem of manual intervention in conventional methods and improve measurement efficiency.