To provide a method for preparing a
transplantation model animal which makes it possible to realize a highly reliable and highly reproducible
transplantation experimental system, in order to design a
transplantation material which ensures performance and quality that are more suitable to clinical
medical care.SOLUTION: A method for evaluating a transplantation material which is similar to that in autoplastic transplantation comprises: a step of administering, to a recipient newborn, a crude extract from a labeled marker expression donor to obtain a recipient which is immune tolerant to the donor; and a step of
transplanting, to the recipient which is immune tolerant, the transplantation material which includes an
artificial graft material that tissue or cells of the labeled marker expression donor cover, adhere to, infiltrate, or include. Thus, the method allows preparation of a transplantation model animal which is similar to that in autoplastic transplantation and which makes it possible to realize a highly reliable and highly reproducible transplantation
experimental system.SELECTED DRAWING: Figure 1