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2 results about "Artificial graft" patented technology

Methods for preparing transplantation model animals for evaluating transplantation materials

PendingCN122341269AImmune toleranceBiology
[Topic] To design transplant materials with performance and quality more suitable for clinical medical use, a method for preparing transplantation model animals is provided, which enables a highly reliable and reproducible transplantation experimental system. [Solution] The evaluation method of the present invention for transplantation materials similar to autologous transplantation enables the preparation of transplantation model animals similar to autologous transplantation, which enables a highly reliable and reproducible transplantation experimental system, by including the following steps: applying a crude extract of a donor expressing a marker to a newborn recipient to obtain a recipient immune to the aforementioned donor; and transplanting transplantation material to the immune-tolerant recipient, wherein the transplantation material comprises an artificial transplantation material covered, adhered to, infiltrated, or contained in the tissue or cells of the donor expressing the marker.
Owner:宮内 浩

Magnetic field guided bionic nerve tract membrane network artificial graft and preparation method thereof

The invention relates to the field of medical biological materials, and discloses a magnetic field guided bionic nerve bundle membrane network artificial graft and a preparation method thereof. An inner core of the magnetic-field-guided bionic nerve bundle membrane network artificial graft is an axially-oriented micron-sized fiber network, and an outer layer of the magnetic-field-guided bionic nerve bundle membrane network artificial graft is a polyethylene glycol diacrylate chitosan composite fiber layer. The bionic bundle membrane-like fiber network can realize full-time efficient repair and regeneration of peripheral neuropathy, the micron-sized distributed axial orientation fiber network provides support for cells, silk fibroin loaded on the fiber provides anchoring points for vascular endothelial cells and Schwann cells, myelination and orientated growth of axons are accelerated, and the application prospect is wide. And high-quality repair of injured / diseased nerves is realized.
Owner:SHANGHAI SIXTH PEOPLES HOSPITAL