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289 results about "Methacrylate copolymer" patented technology
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Methacrylic acid - methyl methacrylate copolymer (1:1), also known as Methacrylic Acid Copolymer, Type A – NF, is an excipient used in pharmaceutical manufacturing. It is a solid white powder with dissolution above pH of 6.0, and is used in enteric coatings for fast dissolution in the upper bowel, for granulation...
A polymer of hydrophobic monomers and hydrophilic monomers is provided. It is also provided a polymer blend that contains the polymer and another biocompatible polymer. The polymer or polymer blend and optionally a biobeneficial material and / or a bioactive agent can form a coating on an implantable device such as a drug delivery stent. The implantable device can be used for treating or preventing a disorder such as atherosclerosis, thrombosis, restenosis, hemorrhage, vascular dissection or perforation, vascular aneurysm, vulnerable plaque, chronic total occlusion, patent foramen ovale, claudication, anastomotic proliferation for vein and artificial grafts, bile duct obstruction, ureter obstruction, tumor obstruction, or combinations thereof.
Extrusion of a mix containing a pharmaceutically active agent can be achieved using a plasticising excipient in an amount sufficient to act as plasticiser and also act as lubricant, thereby avoiding the need for inclusion of a lubricant. The invention provides multiparticulates with controlled release properties, substantially free of lubricant. The present invention is preferably directed to extruded multiparticulates containing an opioid such as oxycodone, an ammoniummethacrylatecopolymer such as Eudragit® RSPO, a plasticising excipient such as preferably stearyl alcohol and a water permeability modifier such as preferably Eudragit® RLPO. The obtained multiparticulates show a release rate profile which is pH-independent.
The invention relates to a dispersion suitable for use as coating agent and binder for pharmaceutical forms, having a solids content of 10–70% by weight consisting ofa) from 90 to 99% by weight of a methacrylatecopolymer consisting of at least 90% by weight of (meth)acrylate monomers containing neutral radicals and having a glass transition temperature Tg of from −20° C. to +20° C. as determined by the DSC method, andb) 1–10% by weight of a nonionic emulsifier having an HLB of from 15.2 to 17.3.
The invention relates to a multilayer dosage form comprised of: a) a neutral core; b) an inner coating consisting of a methacrylatecopolymer; c) an outer coating consisting of a copolymer of which 40 to 95% by weight is composed of radically polymerized C1 to C4 alkyl esters of acrylic acid or of methacrylic acid and of which 5 to 60% by weight is composed of (meth)acrylate monomers having an anionic group in the alkyl radical. The invention is characterized in that the inner coating is essentially comprised of a methacrylatecopolymer, of which at least up to 90% by weight consists of (meth)acrylate monomers with neutral radicals, which, in accordance with DIN 53 787, has a minimum film formation temperature of no higher than 30° C., and which contains the pharmaceutical active substance in bound form.
The present invention relates to amphoteric copolymers which comprise ethyl methacrylate, if appropriate a N-vinyllactam compound, at least one monoethylenically unsaturated carboxylic acid and at least one compound with α,β-ethylenically unsaturated double bond and at least one cationogenic and / or cationic group in copolymerized form, to cosmetic and pharmaceutical compositions which comprise such copolymers, to preparation methods, and to the use of these copolymers.
The invention relates to a dispersion suitable for use as coating agent and binder for pharmaceutical forms, having a solids content of 10-70% by weight consisting of a) from 90 to 99% by weight of a methacrylatecopolymer consisting of at least 90% by weight of (meth)acrylate monomers containing neutral radicals and having a glass transition temperature Tg of from -20° C. to +20° C. as determined by the DSC method, and b) 1-10% by weight of a nonionic emulsifier having an HLB of from 15.2 to 17.3.
Poly methacrylate copolymers are disclosed which comprising from about 60 to about 96 weight percent of a C12-C16 alkylmethacrylate and from about 40 to about 4 weight percent of a C18-C30 alkylmethacrylate and provide excellent low temperature properties to lubricating oils.
The invention relates to modified methacrylic resin, and discloses silicone-modified methacrylic resin as well as a preparation method and application thereof. The silicone-modified methacrylic resin is prepared from 100 parts of functional methacrylatecopolymer, 20-70 parts of active MQ silicone, 100-500 parts of organic solvent, and 0.2-10 parts of catalyst in a manner of evenly mixing. The silicone-modified methacrylic resin is firstly kept still for 10-20 minutes at 70-100 DEG C, and then cured for 1-2 hours at 140-180 DEGC to obtain a heat-resistant hydrophobic coating of the silicone-modified methacrylic resin. The heat resistance of the silicone-modified methacrylic resin disclosed by the invention is obviously improved; the glass-transition temperature can be up to over 250 DEG C; the hydrophobicity and the stain resistance are obviously improved; the water contact angle of a copolymer film can be up to over 120 DEG C; the water absorption of three days is smaller than 0.1%; and the stain resistance is level zero.
Owner:GUANGZHOU CHEM CO LTD CHINESE ACADEMY OF SCI
The present invention relates to a fluorin-containing polymer granule with multilayer core shell structure and thermoplasticpolyolefin products. The gross weight of the fluorin-containing polymer granule include: a) 20 to 80 percent by weight of fluorin-carbon polymer core materials; b) 5-30 percent by weight of intermediate-layer of acrylatecopolymer, methacrylatecopolymer, or their compounds; c) 15-50 percent by weight of polymer outer layer with melting point at 50-100 DEG C; The average granular diameter of fluorin-containing polymer granules is 0.1-10 mm. Fluorin-contain polymer granules of the present invention, being added with thermoplasticpolyolefin melt, can be not only dispersed evenly but significantly improve critical shear rate and obviously speed up the time for the removal of melt rupture; thereby reducing surface defects of extruded products and improving transparency of thin film.
The present invention discloses a method for treating or preventing a bone disorder in a mammal in need thereof comprising orally administering to said mammal a pharmaceutically effective amount of a pharmaceutical composition of at least one bisphosphonate, or a pharmaceutically acceptable salt or esters thereof, and at least one aminoalky methacrylatecopolymer, according to a dosing schedule having a dosing interval selected from once-weekly dosing, twice-monthly dosing, once-monthly, once-quarterly and once-annually dosing. The present invention further discloses a method for treating or preventing a bone disorder in a mammal in need thereof comprising continuously orally administering a unit dosage per-day to said mammal in a short time for a long time therapy.
Poly methacrylate copolymers are disclosed which comprising from about 60 to about 96 weight percent of a C12-C16 alkylmethacrylate and from about 40 to about 4 weight percent of a C18-C30 alkylmethacrylate and provide excellent low temperature properties to lubricating oils.
The invention relates to the technical field of cosmetics and particularly relates to a film-forming oil-control composition and a cosmetic. The film-forming oil-control composition disclosed by the invention is prepared from the following ingredients: trimethylsiloxysilicate, hydroxyapatite and an acrylic(acrylate) / polytrimethylsiloxane methacrylatecopolymer. High-polymer film formers, i.e., the trimethylsiloxysilicate and the acrylic(acrylate) / polytrimethylsiloxane methacrylatecopolymer and special oil taking powder, i.e., the hydroxyapatite are compounded and have a synergistic effect, the anti-sweat friction-resistant effect of a base makeup can be effectively improved, skin can be kept dry and clear through continuously absorbing excessive sebum, the problem of makeup dissolving caused by sebum secretion is solved, and a base makeup choice with excellent makeup holding performance is provided for customers.