4 results about "Claudication" patented technology

Disclosed herein is a further medical use of semaglutide, namely semaglutide in the treatment of intermittent claudication in a human subject with diabetes and peripheral arterial disease. Semaglutide is shown to have a positive impact on symptoms of intermittent claudication and therefore the functional limb capacity and quality of life of patients with type 2 diabetes and peripheral arterial disease.

Disclosed herein is a further medical use of semaglutide, namely semaglutide in the treatment of intermittent claudication in a human subject with diabetes and peripheral arterial disease. Semaglutide is shown to have a positive impact on symptoms of intermittent claudication and therefore the functional limb capacity and quality of life of patients with type 2 diabetes and peripheral arterial disease.

The invention relates to the technical field of pharmaceutical preparations, in particular to a traditional Chinese medicine composition for treating femoral head necrosis, a preparation as well as a preparation method and application of the traditional Chinese medicine composition. The traditional Chinese medicine composition is prepared from the following medicinal materials in parts by weight: 10-30 parts of rhizoma drynariae, 10-20 parts of herba epimedii, 10-20 parts of radix morindae officinalis, 10-20 parts of cortex eucommiae, 10-20 parts of rhizoma chuanxiong, 5-15 parts of flos carthami, 10-20 parts of caulis spatholobi, 5-15 parts of folium ginkgo, 5-15 parts of lumbricus, 5-15 parts of cassia twig and 3-10 parts of honey-fried licorice root. The traditional Chinese medicine composition provided by the invention shows a remarkable treatment effect in an SONFH rat model, can effectively improve the load-bearing function of an affected limb, remarkably increase the load-bearing ratio of the affected limb to a healthy limb and remarkably reduce the claudication score, and is proved to be capable of effectively relieving pain and recovering the load-bearing capacity of the affected limb. Histopathologic detection further shows that the traditional Chinese medicine injection prepared from the traditional Chinese medicine composition provided by the invention has a definite repairing effect on caput femoris tissue lesions.

This invention provides a topical Chinese medicine preparation with the effects of promoting blood circulation, removing blood stasis, relieving pain, and analgesia, and its preparation method. It relates to the field of traditional Chinese medicine pharmaceutical technology. The preparation is made from *Xia Tian Wu*, *Jian Xue Fei*, *Qi Ye Lian*, *Shen Jin Cao*, *Wu Xiang Xue Teng*, *Jiu Long Pan*, *Jing Tian San Qi*, *Jiu Jie Cha*, *Ban Bian Qi*, *Huang Bai*, *Qing Hao*, and *Hei Gu Teng*. This invention's preparation has a reasonable combination of herbs and possesses the effects of promoting blood circulation, removing blood stasis, regulating qi and relieving pain, anti-inflammatory and analgesic properties, improving microcirculation, and regulating blood viscosity. It can significantly increase the pain threshold in mice and effectively relieve pain symptoms. Simultaneously, it can significantly improve microcirculatory disorders in the auricle of mice and increase the rate of change in microvascular diameter. Furthermore, this preparation can effectively improve lameness and mental state in rats with knee osteoarthritis combined with blood stasis, and can effectively improve the state of high blood viscosity, providing a new treatment option for painful diseases, microcirculatory disorders, and related conditions such as knee osteoarthritis caused by blood stasis.