22 results about "Increased blood flow" patented technology

The invention provides a traditional Chinese medicine composition, a traditional Chinese medicine preparation, a preparation method and application, and particularly belongs to the technical field of traditional Chinese medicine preparation. The traditional Chinese medicine composition comprises the following components in parts by weight: 7-11 parts of champignon, 19-29 parts of aloe, 10-14 parts of fructus chebulae immaturus, 5-7 parts of rhizoma zingiberis, 5-7 parts of rhizoma nardostachyos, 4-6 parts of fructus chebulae and 2-4 parts of halite. The traditional Chinese medicine composition can improve the activity of SOD, inhibit the content of MDA, reduce damage of oxygen free radicals to gastric mucosa, effectively relieve inflammatory response, achieve anti-inflammation, improve ulcer surface blood flow, improve gastric mucosa damage, reduce ulcer surfaces and promote ulcer healing, and therefore the protective effect on gastric ulcer is achieved. The results of network pharmacology, molecular docking speculation and Western blot method verification show that the FMST plays an anti-inflammatory role through a TLR4 / MyD88 / NF-kappa B signal channel.

A wearable radiation emitting device with integrated vibration element which operates to provide for the use of radiation treatment in conjunction with vibration treatment. The wearable radiation emitting device with integrated vibration element includes a plurality of LEDs, some of which emit blue visible light and others which emit red visible light and infrared light, and are arranged to direct these emissions to an injury site so as to reduce general pain as well as promote a wearer's recovery by way of increased blood flow and infection prevention. The wearable radiation emitting device with integrated vibration element also includes a plurality of integrated vibrating pads operative to generate vibration around an injury site that also promotes increased blood flow as well as stimulates the lymphatic system, all of which promotes systemic healing and aids in infection prevention and swelling reduction.

Provided herein are FLT1 binding proteins, as well as related nucleic acids, vectors, host cells, pharmaceutical compositions and kits. The present disclosure additionally provides methods of treating a subject in need thereof, including subjects in need of treatment for PAD, CLI, ANOCA, or heart failure (HF). Further provided are methods of increasing VEGF-mediated and / or PlGF-mediated signal transduction in a subject, which, in turn, increases blood flow, capillary density, capillary or coronary growth, and / or cardiac perfusion in the subject. The present disclosure further provides methods of reducing blood pressure and risk of heart failure in a subject. In exemplary embodiments, each of the methods comprise administering to the subject a pharmaceutical composition of the present disclosure. In various embodiments, the pharmaceutical composition comprises a FLT1 binding protein of the present disclosure.

The invention relates to the technical field of medicines, in particular to sound-induced piezoelectric hydrogel as well as a preparation method and application thereof. The method comprises the following steps: 1) synthesizing a nano-plate by adopting a hydrothermal method; or in the process of synthesizing the nano-plate by the hydrothermal method, adding an iron source into the reaction liquid, and carrying out hydrothermal reaction to obtain the iron-doped nano-plate, (2) carrying out lamellar stripping on the nano-plate to obtain a nano-sheet; and 3) preparing gelatin gel, and then mixing the gelatin gel with the nanosheets obtained in the step 2) to obtain the sound-induced piezoelectric hydrogel. The piezoelectric-like material is innovatively applied to treatment of infected wounds, the piezoelectric-like material serves as a novel piezoelectric material, the acoustic heating effect can be rapidly generated under low-power ultrasonic induction so as to treat the biological membrane infected wounds, and in addition, the temperature rise can promote wound healing by increasing the blood flow volume, promoting cell migration and the like.

The utility model discloses a limb pressure sleeve capable of being used for cold and hot compress, which comprises a pressure sleeve body, an air pipe arranged in the pressure sleeve body, a plurality of air bags symmetrically arranged on one side face of the pressure sleeve body, a contact layer arranged on one side face of the pressure sleeve body, a heating film arranged between the contact layer and the pressure sleeve body, and a cable arranged in the pressure sleeve body. A plurality of notches are symmetrically formed in one side face of the contact layer, a storage bag is arranged on one side face of the contact layer and located among the notches, and a second hook-and-loop fastener thorn face is arranged on one side face of the inner wall of the storage bag. The heating film is heated through power supply of the cable, the heating film is a carbon nano tube / TPU composite film, the heating film is started to heat the legs, and heating can enable local blood vessels to expand, increase blood flow, improve the conveying efficiency of oxygen and nutrient substances, accelerate discharge of metabolic waste, reduce blood viscosity and reduce blood flow resistance, so that the legs are protected from being damaged. The pharmaceutical composition is of clinical significance to patients with hyperlipidemia or diabetes mellitus.

The application discloses a kind of nanofiber composite dressings with photothermal synergistic antibacterial effect and its preparation method.The method is by in-situ growth COF is loaded on the fiber membrane, then resveratrol is loaded in COF, finally, PPrGO / RES-COF@PAN nanofiber composite dressings are prepared by drawing filtration reductive graphene oxide coating on the membrane.The PPrGO / RES-COF@PAN nanofiber composite dressings of the application has excellent photothermal performance, can synergistically exert bactericidal effect with resveratrol;At the same time, appropriate temperature rise can increase blood flow and ion diffusion rate across cell membrane, and activate heat shock protein, promote cell migration;In addition, the nanofiber composite dressings has good water vapor permeability, porosity and biocompatibility, and can effectively improve inflammation, has good application value for promoting wound healing.

The invention discloses a tongue exercise and respiration collaborative conditioning method for improving refractory insomnia, and relates to the field of human health conditioning and sleep medicines.The method comprises the steps that tongue exercise exercise of a preset duration is executed in the period before sleep every day, abdominal or inverse abdominal respiration regulation is conducted in a synchronous and matched mode, and therefore tongue muscle groups are activated. In the morning or before afternoon every day, a skin needle therapy (oblique puncturing for 0.5 mm) and a bloodletting therapy are performed on specific acupuncture points (such as Yingwei points) in the oral cavity so as to activate and disperse blood stasis and increase qi and blood flow. Through the synergistic effect of lingual exercise, breathing conditioning and skin needle / bloodletting therapy, the blood supply state of the brain and the heart is improved, so that the intractable insomnia symptom caused by neurasthenia, physical weakness, cardio-cerebral ischemia and the like is relieved from the source. The method emphasizes multi-dimensional collaborative conditioning, can adapt to different crowds, can be dynamically adjusted through effect evaluation, and aims to realize a physical insomnia intervention mode without drug dependence.

The invention belongs to the technical field of health care products, and discloses a composition for improving skin color in multiple ways as well as a preparation method and application thereof. The composition for improving the skin color in multiple ways is prepared from the following components in parts by weight: 5 to 10 parts of paeonia ostii flower extract, 2 to 4 parts of pleurotus citrinopileatus extract and 3 to 6 parts of pomegranate extract. The mass ratio of the paeonia ostii flower extract to the pleurotus citrinopileatus extract is (1.25-5): 1. According to the composition disclosed by the invention, the generation of advanced glycation end products AGEs and reactive oxygen species ROS can be effectively inhibited through the synergistic effect of various active ingredients, the generation of melanin is reduced from the source, and the skin is prevented from blackening and yellowing; collagen synthesis is promoted, and the skin repairing capacity is improved; the blood flow speed is increased, the number of red blood cells is increased, the skin microcirculation is improved, the skin metabolism capability is improved, and then the excellent effect of comprehensively improving the skin color in multiple ways is achieved.

A method for treating a section of skin that includes the epidermis, dermis, and hypodermis. The method includes dermaplaning the section of skin. After dermaplaning, a beam from a non-ablative laser is passed over the section of skin multiple times. The beam of the non-ablative laser further removes dead skin and hair and also warms the underlying dermis and hypodermis. A skin serum is topically applied to the section of skin. The section of skin is treated with electrical arc discharges of a plasma pen to create disruptions in the epidermis. The disruptions created in the epidermis enable the serum to better pass into and through the epidermis. The treated area of skin can then be subjected to light therapy to increase blood flow, promote the healing of the created disruptions, and provide protection against infection.

This invention discloses a casein-derived small molecule peptide with antihypertensive effect and its preparation method, belonging to the field of bioactive peptide technology. The preparation method is as follows: S1, mix casein with water and stir until homogeneous; S2, add a complex protease for enzymatic hydrolysis, then add bromelain for further enzymatic hydrolysis to inactivate the enzyme; S3, centrifuge the mixture; S4, heat the separated mixture, add activated carbon for adsorption, then add diatomaceous earth, stir until homogeneous, and filter; S5, further filter through a membrane; S6, concentrate the mixture, sterilize, and dry to obtain the casein-derived small molecule peptide. The casein-derived small molecule peptide of this invention can effectively lower blood pressure by inhibiting ACE activity and blocking the production of angiotensin II. This small molecule peptide significantly increases blood flow activity and angiotensin II content in a hypertensive model zebrafish, exhibiting a dose-dependent effect, achieving the same effect as the antihypertensive drug captopril, and with an efficacy concentration that is half that of the positive control drug.

The application discloses a shunt, comprising a tube body, comprising an outer skeleton and an inner skeleton connected, a first through hole is formed on the outer skeleton, the first through hole is arranged along the axial direction of the outer skeleton, the inner skeleton is located on the inner side of the first through hole, the outer wall of the inner skeleton is at least partially spaced from the inner wall of the first through hole, a second through hole is formed on the inner skeleton, and the second through hole is arranged along the axial direction of the inner skeleton. Thus, by spacing the outer wall of the inner skeleton from the inner wall of the first through hole, a certain spacing distance is formed between the outer wall of the inner skeleton and the inner wall of the first through hole, so that a certain deformation space is formed between the inner skeleton and the inner wall of the first through hole. After the left atrial pressure of the patient increases, the inner skeleton can expand towards the radial outside under the pressure of the blood flow, so that the area of the radial section of the second through hole increases, the blood flow passing amount per unit area is increased, and the long-term increased blood flow pressure in the left atrium can be adapted.

The invention relates to a system (1) and method for detecting malfunctions of the neurovascular coupling of a user of a device that can be worn or implanted on the head, in particular a hearing aid (2), long-term monitoring being carried out with the aid of a device worn by the user, in particular a hearing aid. The device has a signal processing unit (8) and a memory (16). The system (1) also has at least two sensors (18, 20, 22), namely a sensor (20) for detecting brain activity and a blood sensor (18, 22) for detecting blood flow to the brain. The at least two sensors (4, 18, 20, 22) are connected to the signal processing unit (8) for transmitting sensor data (A, B), namely brain activity data (A) and blood flow data (B). The signal processing unit (8) is designed to process the sensor data (A, B) in such a way that characteristic data, in particular a characteristic value (K) for a correlation, in particular a time delay between increased brain activity and increased blood flow caused thereby, is determined, and reference characteristic data and in particular a reference characteristic value (RK) are formed therefrom over a relatively long observation period (Z) as a measure of the time delay Z. The reference characteristic data are compared with instantaneous characteristic data recorded later and a warning signal (W) is emitted in the event of an inadmissible deviation.

The present invention provides an immediate volumizing effect, a refreshing sensation, and wrinkle removal effects by including hyaluronic acid and peptides, and provides long-term improvement in lip volume and reverse skin aging effects by including an extract of Silybum marianum petals and an extract of Glycyrrhiza glabra leaves. In addition, the purpose of the present invention is to provide a natural plumping effect through long-term improvement in lip volume, amelioration of wrinkles, and increased blood flow by mixing an extract of Silybum marianum petals, which is an anti-aging component that removes and inhibits senescent cells, with ingredients such as hyaluronic acid and peptides that induce a natural plumping effect by ameliorating wrinkles and increasing blood flow.

There is provided in accordance with an exemplary embodiment of the invention a method and / or a device of treating tissue near a first lumen comprising inserting an energy emission element into a second lumen and delivering energy in an amount sufficient to cause one or more spaced apart areas of tissue damage at preselected locations in tissue near the first lumen. There is also provided a method and / or a device for treating a carotid artery wall, for example, to reduce signal conduction. There is also provided a method and / or a device for treating a wall of a lumen in a limb, for example, to increase blood flow. There is also provided a method and / or a device for treating a wall of a heart, for example, to stop abnormal signal propagation.

Disclosed embodiments relate to apparatuses and methods for applying negative pressure to a tissue site or skin site to prepare for a surgical operation. The apparatuses and methods can be used to increase blood flow at or near the tissue site. Therapeutic gas can also be applied to prepare the tissue site for the operation. Antimicrobial and antiseptic agents can also be applied to reduce the bioburden at the tissue site.

The present disclosure proposes a kit (100) and composition for treating edema, necrotizing fasciitis, restoring muscle perfusion, and limiting bacterial spread. The kit (100) comprises a topical antibiotic cream (102), plurality of antiseptic gauzes (104), an ordho cloth roller bandage (106), a crepe roller (108), a super absorbent gamjee roller (110), and a pair of surgical gloves (112). The proposed kit (100) treats edema of any type, including prevention of death through early intervention, avoiding surgery, minimizing morbidity, and reducing patient expenditure. The proposed kit (100) decreases muscle compartment pressure, increases blood flow to affected muscles, and prevents tissue necrosis. The proposed kit (100) significantly reduces patient expenditure compared to conventional treatments, making it affordable for a broader population.

The present disclosure provides compositions and methods for treating pulmonary hypertension. The compositions and methods are based on administering a NO-releasing compound, such as nitrite, to a subject in need thereof in an amount sufficient to increase the level of circulating nitric oxide (NO), a potent vasodilator, thereby reducing the subject's blood pressure and increasing blood flow.

This invention discloses a concentrated tomato product that increases blood flow and its preparation method. On a dry basis, the product contains 3.0 g / 100g of cis-lycopene, 1.5 g / 100g of total phytosterols, and 0.8 g / 100g of total polyphenols. The phytosterols are composed of β-sitosterol and stigmasterol, and the polyphenols are composed of chlorogenic acid, caffeic acid, and ferulic acid. This invention maximizes the preservation of the tomato's nutritional components by screening high-lycopene tomato varieties and optimizing pretreatment, enzyme inactivation, and juicing process parameters. Simultaneously, by precisely adding exogenous phytosterols, polyphenol extracts, and synergistic components such as Omega-3 fatty acids and vitamin E, a multi-component synergistic system is constructed. The components work together synergistically to significantly enhance the product's function of increasing blood flow, effectively improving microcirculation, reducing blood viscosity, and providing protection for cardiovascular health.

A method of treating vaginal tissue atrophy in a female subject, the method including the steps of engaging an energy delivery element with tissue in or around the subject's vagina; applying energy to the tissue from the energy delivery element; and increasing blood flow to internal vaginal tissue to an increased level above a baseline level of blood flow to the internal vaginal tissue, the increased level of blood flow to the internal vaginal tissue persisting after the applying step ceases. The invention also provides devices for performing this therapy.

There is provided in accordance with an exemplary embodiment of the invention a method and / or a device of treating tissue near a first lumen comprising inserting an energy emission element into a second lumen and delivering energy in an amount sufficient to cause one or more spaced apart areas of tissue damage at preselected locations in tissue near the first lumen. There is also provided a method and / or a device for treating a carotid artery wall, for example, to reduce signal conduction. There is also provided a method and / or a device for treating a wall of a lumen in a limb, for example, to increase blood flow. There is also provided a method and / or a device for treating a wall of a heart, for example, to stop abnormal signal propagation.

A dental composition for expediting recovery from dental anesthesia comprises Vitamin C (75-2,000 mg), caffeine (30-400 mg), and beet root extract (250-7,000 mg) in synergistic combination. The composition addresses prolonged numbness following dental procedures by employing multiple complementary mechanisms: Vitamin C counteracts anesthetic effects through neurochemical pathways, beet root extract enhances vascular delivery via increased blood flow, and caffeine accelerates metabolic clearance. Administered as capsules immediately after or during dental procedures, the composition reduces post-procedural numbness duration, prevents soft tissue injuries from inadvertent biting, restores normal speech and eating function sooner, and promotes wound healing. The invention provides a safe, effective solution to a long-standing problem in dental anesthesia management.

Provided herein are FLT1 binding proteins, as well as related nucleic acids, vectors, host cells, pharmaceutical compositions and kits. The present disclosure additionally provides methods of treating a subject in need thereof, including subjects in need of treatment for PAD, CLI, ANOCA, or heart failure (HF). Further provided are methods of increasing VEGF-mediated and / or PlGF-mediated signal transduction in a subject, which, in turn, increases blood flow, capillary density, capillary or coronary growth, and / or cardiac perfusion in the subject. The present disclosure further provides methods of reducing blood pressure and risk of heart failure in a subject. In exemplary embodiments, each of the methods comprise administering to the subject a pharmaceutical composition of the present disclosure. In various embodiments, the pharmaceutical composition comprises a FLT1 binding protein of the present disclosure.