189 results about "Blood flow volume" patented technology

The embodiment of the invention provides a continuous blood oxygen monitoring system in extracorporeal circulation and a control method thereof. The continuous blood oxygen monitoring system comprises a vein sensor, an artery sensor, a blood flow sensor, an oxygen sensor, a carbon dioxide sensor, a controller and a display, the vein sensor monitors the vein blood oxygen saturation degree; the artery sensor monitors arterial oxygen saturation and hematocrit; the blood flow sensor monitors the blood flow of the artery pipeline; the oxygen sensor monitors the oxygen concentration of the oxygenator; the carbon dioxide sensor monitors the carbon dioxide concentration of the oxygenator; the display provides an interaction control, responds to a trigger operation acting on the interaction control, sends an interaction instruction to the controller, and updates information displayed in an interaction interface according to the control of the controller; the controller receives the interaction instruction and executes processing corresponding to the interaction instruction; the processing includes controlling display information of the display; the display information comprises information corresponding to the monitoring parameters. The scheme ensures the safety and effectiveness of the treatment process.

The invention relates to a method for determining a total fluid volume flow (1) in the region of an implanted vascular support system (2), comprising the following steps: a) determining a reference temperature (3) of the fluid, b) determining a motor temperature (4) of an electric motor (5) of the support system (2), c) determining the thermal dissipation loss (6) of the electric motor (5), d) ascertaining the total fluid volume flow (1) using the reference temperature (3), the motor temperature (4), and the thermal dissipation loss (6) of the electric motor (5).

The invention belongs to the technical field of human body electroencephalogram signal processing and brain regulation and control, and provides a multi-modal coupling type closed-loop electrical stimulation sleep synergy signal regulation and control device and system.The technical scheme includes that multi-modal physiological signals including EEG slow wave power, cerebral blood flow and cerebrospinal fluid flow signals are obtained; screening and preprocessing the obtained multi-modal physiological signal to obtain a preprocessed multi-modal signal; calculating the time domain correlation between the EEG slow wave power and the cerebral blood flow and the frequency domain coherence between the cerebral blood flow and the cerebrospinal fluid flow signal; introducing regulatory factors of time domain correlation of EEG slow wave power and cerebral blood flow and frequency domain coherence of cerebral blood flow and cerebrospinal fluid flow signals to obtain a signal stimulation intensity calculation formula; and optimizing the signal stimulation intensity by combining a signal stimulation intensity calculation formula and the constructed double-layer optimization architecture to obtain the optimized signal stimulation intensity. And an accurate sleep regulation and control signal is generated.

The invention relates to the technical field of data processing, and discloses a method and system for predicting a hypotension risk in dialysis based on machine learning. The method comprises the following steps: calculating an ultrafiltration rate-blood pressure decreasing amplitude coupling coefficient by collecting ultrafiltration rate, blood flow volume, transmembrane pressure and blood pressure data in a dialysis process, obtaining a dialysis tolerance index in combination with a vascular compliance parameter, and constructing a stage weighting function according to dialysis duration to determine a weight coefficient of each period; and performing weighted calculation with individual baseline dialysis tolerance to set a personalized risk threshold value, and establishing a sliding window prediction mechanism to predict the probability of occurrence of hypotension in the future. The problems that a static prediction mode cannot adapt to dynamic changes in the dialysis process and is lack of personalized risk assessment are solved, and the accuracy and timeliness of hypotension risk prediction in dialysis are improved.

The invention discloses a comprehensive oral diagnosis and treatment system, which relates to the technical field of oral medicine and medical instruments and comprises a tooth movement monitoring module, a low-intensity pulsed ultrasound module, a high-intensity focused ultrasound module, a blood flow monitoring module, a control module, a wireless communication module and a terminal module. According to the invention, comprehensive monitoring and treatment of tooth movement, periodontal tissue health, temporomandibular joint function and oral cavity related muscle dynamics of a patient can be realized. Meanwhile, the equipment integrates advanced low-intensity pulsed ultrasound and high-intensity focused ultrasound technologies, and has the functions of periodontal tissue repair, muscle relaxation and joint soft tissue treatment. Besides, through the wireless communication module and the terminal module, the system can provide real-time health data monitoring and personalized diagnosis and treatment schemes, and is widely suitable for patients with orthodontics, periodontal diseases, temporomandibular joint disorder and other related oral dysfunctions.

The invention discloses a brain tumor disease treatment effect evaluation method, and belongs to the technical field of radiotherapy plan evaluation, and the method specifically comprises the steps: obtaining the brain multi-modal image data of a patient, and extracting a three-dimensional tumor region and a corresponding perfusion parameter; constructing a biological target region hierarchical structure containing a tumor overall region and an anoxic subregion; a relative hypoxia degree parameter is obtained by calculating the cerebral blood flow ratio of the hypoxia subregion to other regions of the tumor; historical treatment case data are deconstructed, and a dose-curative effect associated parameter set is established; training and outputting a dose adjustment strategy model for the hypoxia subregion; and generating a final radiotherapy dose planning scheme according to a dose adjustment value output by the model in combination with a clinical guide basic dose. Through a data-driven dose decision-making mechanism, the limitation of traditional uniform dose irradiation is overcome, so that an objective and reliable evaluation basis is provided for clinical selection and optimization of personalized treatment schemes.

The present invention relates to the technical field of medical image processing, and disclosed are a method and device for calculating blood flow at any position of a blood vessel tree. The method comprises: acquiring angiography image sequences, and performing structure extraction on images in the angiography image sequences to obtain two-dimensional blood vessel skeleton lines; performing three-dimensional reconstruction on the basis of the two-dimensional blood vessel skeleton lines to obtain a three-dimensional blood vessel model; determining a corresponding target blood vessel area on the basis of the three-dimensional blood vessel model, and calculating corresponding average blood flow in the target blood vessel area on the basis of transfer frame quantities corresponding to the angiography image sequences; reconstructing a reference blood vessel diameter on the basis of a corresponding blood vessel diameter in the target blood vessel area, and determining a blood vessel stenosis area on the basis of the blood vessel diameter and the reference blood vessel diameter; and calculating corresponding target blood flow at a target position in the target blood vessel area on the basis of the blood vessel stenosis area and the average blood flow. According to the present invention, blood flow at any position of blood vessels can be accurately calculated.

A method may be performed by a system including a processor in communication with an extraluminal imaging device and an intravascular pressure measurement device. The method includes acquiring a contrast agent angiography image in a blood vessel having a contrast agent; based on the contrast agent angiography image, generating a reconstructed geometric object of the blood vessel and estimating blood flow in the blood vessel; implementing a physical model of blood distribution using the reconstructed geometry, determining output parameters based on the blood pressure value and the blood flow volume; and generating a harmonic hemodynamic parameter based on the output parameter. The harmonized hemodynamic parameter is adjusted based on measurements taken at various vascular conditions.

The invention relates to the field of medical image processing, and discloses an AI analysis method for fundus image blood vessels, which comprises the following steps: acquiring images at different time points of the same fundus, respectively reconstructing a blood vessel topology network and measuring geometric parameters; constructing an equivalent blood flow resistance network based on the network and a preset fluid dynamic model, and calculating a static function field containing parameters such as virtual blood flow at each time point; spatial registration is carried out on the two time point function fields, differential calculation is carried out on corresponding blood vessel segment parameters after registration, a differential data set is generated, a visual differential stress evolution graph is constructed, and then an analysis result of fundus image blood vessels is generated. According to the method, dynamic and multi-dimensional quantitative evaluation of the function evolution process of the fundus vascular network under the stress reaction is realized through space-time comparison and function modeling, and an accurate and comprehensive decision basis is provided for early diagnosis, illness monitoring and curative effect evaluation of related fundus diseases.

The flow-adjustable perfusion balloon catheter comprises a catheter body, a balloon capable of being filled and a catheter base, a push rod channel and a filling channel are arranged in the catheter body, the filling channel is communicated with an inner cavity of the balloon, and a first connector and a second connector are arranged on the catheter base. Micropores are formed in the positions, located at the near end and the far end of the balloon, of the catheter body and are the near-end micropore and the far-end micropore respectively, the near-end micropore and the far-end micropore are communicated through a blood flow channel formed in the catheter body, and a blocking piece capable of blocking the near-end micropore or the far-end micropore is arranged in the blood flow channel. A push rod is arranged in the push rod channel, and the far end of the push rod is connected with the near end of the plugging piece. Compared with the prior art, by arranging the blood flow channel, effective circulation of blood flow can still be achieved after balloon plugging in the operation, complications caused by ischemia or hypertension in the operation are avoided, the perfusion blood flow can be adjusted in time according to different patient conditions, and the success rate of the operation is increased.

A system for monitoring hemodynamic effectiveness includes a lead assembly including a lead body configured to deliver electrical stimulation or to deliver a fluid. The system includes at least one stimulation source including a drug pump or a pulse generator, a sensing device configured to detect a hemodynamic property of a body part, and a processor configured to determine hemodynamic effectiveness based on the detected hemodynamic property. Hemodynamic properties may include vasodilation, vasoconstriction, increased blood flow, decreased blood flow, or other hemodynamic changes. A method for providing treatment includes positioning a lead body adjacent to a blood vessel, obtaining a baseline hemodynamic property, administering stimulation, detecting an updated hemodynamic property, and determining hemodynamic effectiveness based on a change between the baseline and updated hemodynamic properties. A closed-loop treatment system adjusts treatment values based on measurements detected by the sensing device to cause stimulation to reach target values.

The present technology can be used to selectively heat one or more diseased regions in the lung while limiting heating of healthy regions and surrounding tissue. This heating provides a therapeutic effect. Selective heating of diseased tissue can be achieved by exposing the lung to an electromagnetic field to cause dielectric or eddy current heating. The present technology is particularly useful for treating emphysema because the diseased regions of emphysema patients have reduced blood flow. The diseased regions will heat up quickly while healthy tissue will be cooled by blood flow. This is particularly effective for treating emphysema because the lung has a small mass and high blood flow. In one described embodiment, the frequency of the electromagnetic radiation is chosen to satisfy certain resonance conditions of the device. In another described embodiment, a coil is used to apply the electromagnetic radiation, the geometric parameters of the coil being chosen so that an electric field maximum is produced in the region to be heated. In another described embodiment, a pair of electromagnetic energy signal applicators are used to apply the electromagnetic radiation, the pair of electromagnetic energy signal applicators being positioned to surround the torso of the patient, one electromagnetic energy signal applicator being positioned cephalad relative to the treatment region and the other electromagnetic energy signal applicator being positioned caudal relative to the treatment region, and the pair of electromagnetic energy signal applicators being shaped to encircle or partially encircle the periphery of the torso.

Embodiments of the present disclosure relate to blood flow regulation systems and associated methods, and in certain embodiments, include an adjustable blood flow regulation device including an inner tube, an inflatable member coupled to the inner tube, a proximal control handle including a controller operatively coupled to the member and configured to control inflation of the member, and a downstream tip member coupled to a distal portion of the inner tube distal of the member. The tip member is coupled to a first fluid pressure sensor. A second fluid pressure sensor is coupled to a portion of the inner tube proximal of the member.

The application discloses a kind of peripheral blood vessel tension measurement method and device based on ultrasound, it is related to the technical field of hemodynamics monitoring.The application collects the ultrasound image and arterial spectrum data of peripheral artery, obtains the pressure gradient variation characteristic parameter of peripheral artery from the ultrasound image of peripheral artery;According to the arterial spectrum data of continuous multiple heart cycles in the time period set according to peripheral artery, the resistance characteristic parameter of the rise and fall of blood flow velocity and the forward blood flow of peripheral artery are obtained;The pressure gradient variation characteristic parameter, resistance characteristic parameter and forward blood flow are used, which comprehensively reflect the peripheral arterial vessel tension situation.The application can use ultrasound to realize non-invasive, convenient and dynamic real-time reflection of peripheral vessel tension, and the hemodynamic changes can be fed back through the peripheral vessel tension waveform diagram, which is beneficial to early warning and helpful for health management and clinical guidance.

Embodiments of the present application provide a blood vessel detection system, an electronic device, a storage medium and a computer program product. The system comprises a catheter and a host. The catheter is provided with a first signal collector and a second signal collector. The first signal collector is used to collect intravascular ultrasound echo signals, and the second signal collector is used to collect blood flow source signals. The host is used to generate an intravascular ultrasound image according to the intravascular ultrasound echo signals of a blood vessel to be detected, determine blood flow information of the blood vessel to be detected according to the blood flow source signals of the blood vessel to be detected, register the intravascular ultrasound image and the blood flow information in the collection time, determine first blood flow information matched by a first intravascular ultrasound image when a blood vessel lumen reaches a maximum expansion state and second blood flow information matched by a second intravascular ultrasound image when the blood vessel lumen is in a resting state according to a registration result, and calculate a blood flow reserve characteristic value according to the determined blood flow information. In this way, comprehensive evaluation of blood vessel morphology and function can be achieved.

The present application relates to the technical field of blood monitoring, in particular to a vascular health assessment and intelligent nursing system for hemodialysis patients. The degree of venous reflux obstruction is determined based on the change trend and degree of venous pressure data within each dialysis period, and the degree of inconsistency between the change trends of venous pressure data and transmembrane pressure data. The degree of arterial supply obstruction is determined based on the change trend and degree of arterial pressure data within each dialysis period. The suspected internal fistula obstruction period is determined based on the change trend of the degree of venous reflux obstruction and the degree of arterial supply obstruction. The nursing intervention prompting degree of the patient to be tested is determined based on the relationship between the blood flow data and arterial pressure data of each dialysis stage of the patient to be tested within the suspected internal fistula obstruction period, and the blood flow data of the non-dialysis stage. The internal fistula nursing scheme is determined. The present application realizes early warning of internal fistula dysfunction based on the change of venous and arterial pressure of the blood circulation loop during dialysis.

Provided is a method and a system for noninvasive measurement of blood viscosity based on oxygen saturation and blood flow rate, which may easily and quickly calculate the blood viscosity by using the method and the system for noninvasive measurement of blood viscosity based on oxygen saturation and blood flow rate, thereby enabling immediate obtaining of the blood viscosity.

To provide a device for preventing periodontal disease, which aims to prevent periodontal disease by increasing the blood flow in the gums through brushing with a toothbrush, rectifying the tissue fluid produced in the gums and guiding it to the attached subepithelial connective tissue, and causing the tissue fluid to seep into the gingival sulcus through the gaps between attached epithelial cells, thereby generating a pseudo self-cleaning action of the gingival sulcus. [Solution] Using a motor for an arrow feather-shaped brush, the arrow feather-shaped brush is continuously rotated from the attached gum through the cervical area toward the gingival sulcus opening, with the product of the number of rows of brush bristles that make up the feather portion of the arrow feather-shaped brush 1 and the number of rotations per minute of the motor being in the range of 240 times per minute or less, and the rotating arrow feather-shaped brush is vibrated using a vibration motor 12.

To quantitatively measure a blood flow during INOCA examination without using a sensor wire.SOLUTION: A medical image processing device according to an embodiment includes an acquisition unit, a first calculation unit, a second calculation unit, and a display control unit. The acquisition unit acquires a 0-th contrast image in a case where a heart with non-obstructive coronary artery disease is in a reference state, a first contrast image in a case where the heart is in an acetylcholine loading state, and a second contrast image in a case where the heart is in an adenosine loading state. The first calculation unit calculates a first blood flow ratio representing a ratio between a 0-th blood flow amount of a myocardium in the reference state and a first blood flow amount of the myocardium in the acetylcholine loading state on the basis of the 0-th contrast image and the first contrast image. The second calculation unit calculates a second blood flow ratio representing a ratio between the 0-th blood flow amount and a second blood flow amount of the myocardium in the adenosine loading state on the basis of the 0-th contrast image and the second contrast image. The display control unit causes the first blood flow ratio and the second blood flow ratio to be displayed side by side on a display.SELECTED DRAWING: Figure 1

The invention provides a medical image processing apparatus and an X-ray diagnostic apparatus, which can quantitatively measure blood flow without using a sensor line during INOCA examination. The medical image processing apparatus includes a processing circuit. The processing circuit acquires a zeroth contrast image when the heart of a subject is in a reference state, a first contrast image when the heart is in an acetylcholine-loaded state, and a second contrast image when the heart is in an adenosine-loaded state. The processing circuit calculates, on the basis of the zeroth contrast image and the first contrast image, a first blood flow ratio indicating the ratio of a zeroth blood flow rate of the cardiac muscle in a reference state to a first blood flow rate of the cardiac muscle in an acetylcholine-loaded state. On the basis of the zeroth contrast image and the second contrast image, the processing circuit calculates a second blood flow ratio indicating the ratio of the zeroth blood flow to a second blood flow of the cardiac muscle in an adenosine-loaded state. The processing circuit displays the first blood flow ratio and the second blood flow ratio on the display in parallel.

The invention relates to the technical field of medical image processing, in particular to a hemodialysis internal arteriovenous fistula thermal image intelligent analysis and early warning system and method, and the system comprises an infrared thermal imaging device, an image processing device, a server, a mobile device and a cloud analysis platform. The method is characterized in that the image processing equipment comprises a thermal image analysis module, a dynamic image analysis module and a data integration module, the thermal image analysis module introduces a differential geometry theory, maps an internal fistula thermal image into a parameterized temperature manifold, and obtains a parameterized temperature manifold through geodesic analysis and vector field topology analysis; calculating a geodesic deviation index and a topological characteristic change rate index, and accurately evaluating the internal fistula function state; the dynamic image analysis module calculates parameters such as the blood vessel outer diameter, the blood flow and the heat conduction index; the data integration module collects data of all the modules to form comprehensive evaluation, remote evaluation guidance of experts is supported through a remote consultation function, early warning is achieved based on time sequence topology changes, and internal fistula function deterioration is predicted 7-10 days in advance.

An ultrasound diagnostic apparatus includes a display that displays a B-mode image in which at least a blood vessel region is imaged; a processor configured to accept designation of a position of the blood vessel region on the B-mode image; detect a vascular wall by performing image analysis on the B-mode image on the basis of the designated position of the blood vessel region; calculate a cross-sectional area of a blood vessel on the basis of the detected vascular wall; set a Doppler gate within the blood vessel region on the B-mode image on the basis of the detected vascular wall; calculate a blood flow velocity on the basis of Doppler data in the Doppler gate; and measure a blood flow volume on the basis of the cross-sectional area of the blood vessel and the blood flow velocity, and display a measurement result on the display.

We report a method of treating an epileptic seizure in a patient, comprising: detecting said epileptic seizure, based on body data from said patient; and reducing a flow of blood to a brain of said patient in response to said detected seizure; wherein said reducing is effected by: increasing the parasympathetic input to said patient's heart, such as by electrically stimulating a parasympathetic nervous structure, applying cooling energy to a sympathetic nervous structure, or administering a cholinergic or a sympatho-blocking agent to said patient. We also report a medical device system configured to implement the method. We also report a non-transitory computer readable program storage unit encoded with instructions that, when executed by a computer, perform the method.

A method for non-invasive quantitative measurement of cerebrovascular reserve (CVR) and cerebral blood flow (CBF) with 15O-water positron emission tomography (PET) in a human.

A speckle contrast optical spectroscopy techniques for measuring cerebral blood metrics such as cerebral blood flow and / or cerebral blood volume at multiple regions of the brain using one or more light sources and detectors of a plurality of channels disposed on a headset worn by a subject and detecting a brain injury or other brain malfunction by comparing cerebral blood metrics measurement at different regions.

The invention provides a training method, a recognition method, a system and equipment for a fistula anomaly recognition model. The training method comprises the steps that a training data set is acquired, the training data set comprises a plurality of pieces of sample data, and each piece of sample data comprises fistula anomaly recognition influence parameters and corresponding sample anomaly recognition results; wherein the fistula abnormity identification influence parameters comprise fistula tremor signals and blood flow and / or blood vessel diameter; and training a preset model based on the plurality of sample data to obtain a fistula anomaly recognition model. According to the method, the fistula tremor signal, the blood flow and / or the blood vessel diameter and the corresponding sample anomaly recognition result are jointly used as the sample data to train the model, the accuracy of the fistula anomaly recognition model is improved, anomaly recognition can be performed on the fistula in real time, accurate evaluation about the internal arteriovenous fistula blood vessel function is provided for doctors, and the accuracy of the fistula anomaly recognition model is improved. Therefore, various complications of internal arteriovenous fistula can be timely and accurately treated, and the safety of a patient is guaranteed.

The application belongs to the technical field of medicine, and particularly relates to a muscone derivative, a preparation method and application thereof. The muscone derivative cyclopentadecanedione monoxime has obvious advantages over muscone and other derivatives in improving the MCAO rat mNSS score, microcirculation blood flow, reducing the cerebral infarction rate, the cortical and hippocampal neuron necrosis rate, and the brain water content, and increasing the SOD and CAT contents of the rat brain tissue which are abnormally reduced due to ischemia, and is a potential effective drug for cerebral ischemia-reperfusion injury.

In the present invention, a control unit (90) of an extracorporeal circulation device (1) capable of ensuring an ideal blood flow rate for a patient when performing VA-ECMO comprises: a calculation unit (91) that calculates an ideal flow rate and pump head pressure from patient-specific information; and a transmission unit (92) that transmits, to a fluid replacement device (70) for performing fluid replacement, water amount data obtained through measurement by a measurement device (80) for measuring the water amount of the patient. The control unit (90) gives a fluid replacement instruction to the fluid replacement device (70) via the transmission unit (92) on the basis of the pressure of the inside of a blood circuit (20) measured by pressure measurement units (45, 46), the flow rate of the inside of the blood circuit (20) measured by a flow rate measurement unit (47), and the water amount data obtained through measurement by the measurement device (80).

The invention relates to a side-end internal arteriovenous fistula stent and a use method, and belongs to the technical field of implantable medical equipment. Comprising a transfer pipe, and a fixing groove is formed in the tail end of the transfer pipe; the clamping block is arranged in the fixing groove in a sliding manner; a stent body having a connection passage; the two first fixing claws are oppositely installed at one end of the connecting channel, positioning holes are formed in the first fixing claws, the positioning holes are connected with the clamping blocks in a clamped mode, and the space between the first fixing claws is used for assisting the second fixing claws in fixing the blood vessel wall; the two second fixing claws are oppositely mounted at the other end of the connecting passage, and the second fixing claws are used for abutting against and being fixed to the blood vessel wall after being released. The technical problems that in the prior art, due to the fact that a spiral classifier is used for conducting, the blood flow volume after communication is small, the pressure in arteriovenous fistula blood vessels is high, thrombus is easily formed, and thrombus is easily blocked in a support are solved.

This application provides a medical image processing method and system. The method includes: acquiring vascular image volume data from photon-counting computed tomography scans of a target region; based on the vascular image volume data, performing skeletonization processing on the vascular network, extracting multiple skeleton points in the vascular network, and forming a vascular centerline network according to the connection relationships between the skeleton points; identifying endpoints and bifurcation points from the vascular centerline network, thereby dividing the vascular centerline network into several continuous and unbifuzzy vascular segments, and constructing a vascular centerline diagram structure based on each vascular segment; establishing and solving a blood flow analysis model based on the vascular centerline diagram structure to obtain the blood flow analysis results of the vascular network; wherein, the blood flow analysis results include the blood flow rate and / or pressure difference between the two ends of each vascular segment. This application improves the accuracy of the blood flow analysis results.