99 results about "Blood flow volume" patented technology

The invention discloses a brain tumor disease treatment effect evaluation method, and belongs to the technical field of radiotherapy plan evaluation, and the method specifically comprises the steps: obtaining the brain multi-modal image data of a patient, and extracting a three-dimensional tumor region and a corresponding perfusion parameter; constructing a biological target region hierarchical structure containing a tumor overall region and an anoxic subregion; a relative hypoxia degree parameter is obtained by calculating the cerebral blood flow ratio of the hypoxia subregion to other regions of the tumor; historical treatment case data are deconstructed, and a dose-curative effect associated parameter set is established; training and outputting a dose adjustment strategy model for the hypoxia subregion; and generating a final radiotherapy dose planning scheme according to a dose adjustment value output by the model in combination with a clinical guide basic dose. Through a data-driven dose decision-making mechanism, the limitation of traditional uniform dose irradiation is overcome, so that an objective and reliable evaluation basis is provided for clinical selection and optimization of personalized treatment schemes.

The present application relates to the technical field of blood monitoring, in particular to a vascular health assessment and intelligent nursing system for hemodialysis patients. The degree of venous reflux obstruction is determined based on the change trend and degree of venous pressure data within each dialysis period, and the degree of inconsistency between the change trends of venous pressure data and transmembrane pressure data. The degree of arterial supply obstruction is determined based on the change trend and degree of arterial pressure data within each dialysis period. The suspected internal fistula obstruction period is determined based on the change trend of the degree of venous reflux obstruction and the degree of arterial supply obstruction. The nursing intervention prompting degree of the patient to be tested is determined based on the relationship between the blood flow data and arterial pressure data of each dialysis stage of the patient to be tested within the suspected internal fistula obstruction period, and the blood flow data of the non-dialysis stage. The internal fistula nursing scheme is determined. The present application realizes early warning of internal fistula dysfunction based on the change of venous and arterial pressure of the blood circulation loop during dialysis.

Provided is a method and a system for noninvasive measurement of blood viscosity based on oxygen saturation and blood flow rate, which may easily and quickly calculate the blood viscosity by using the method and the system for noninvasive measurement of blood viscosity based on oxygen saturation and blood flow rate, thereby enabling immediate obtaining of the blood viscosity.

The invention relates to the technical field of medical image processing, in particular to a hemodialysis internal arteriovenous fistula thermal image intelligent analysis and early warning system and method, and the system comprises an infrared thermal imaging device, an image processing device, a server, a mobile device and a cloud analysis platform. The method is characterized in that the image processing equipment comprises a thermal image analysis module, a dynamic image analysis module and a data integration module, the thermal image analysis module introduces a differential geometry theory, maps an internal fistula thermal image into a parameterized temperature manifold, and obtains a parameterized temperature manifold through geodesic analysis and vector field topology analysis; calculating a geodesic deviation index and a topological characteristic change rate index, and accurately evaluating the internal fistula function state; the dynamic image analysis module calculates parameters such as the blood vessel outer diameter, the blood flow and the heat conduction index; the data integration module collects data of all the modules to form comprehensive evaluation, remote evaluation guidance of experts is supported through a remote consultation function, early warning is achieved based on time sequence topology changes, and internal fistula function deterioration is predicted 7-10 days in advance.

An ultrasound diagnostic apparatus includes a display that displays a B-mode image in which at least a blood vessel region is imaged; a processor configured to accept designation of a position of the blood vessel region on the B-mode image; detect a vascular wall by performing image analysis on the B-mode image on the basis of the designated position of the blood vessel region; calculate a cross-sectional area of a blood vessel on the basis of the detected vascular wall; set a Doppler gate within the blood vessel region on the B-mode image on the basis of the detected vascular wall; calculate a blood flow velocity on the basis of Doppler data in the Doppler gate; and measure a blood flow volume on the basis of the cross-sectional area of the blood vessel and the blood flow velocity, and display a measurement result on the display.

A speckle contrast optical spectroscopy techniques for measuring cerebral blood metrics such as cerebral blood flow and / or cerebral blood volume at multiple regions of the brain using one or more light sources and detectors of a plurality of channels disposed on a headset worn by a subject and detecting a brain injury or other brain malfunction by comparing cerebral blood metrics measurement at different regions.

The invention provides a training method, a recognition method, a system and equipment for a fistula anomaly recognition model. The training method comprises the steps that a training data set is acquired, the training data set comprises a plurality of pieces of sample data, and each piece of sample data comprises fistula anomaly recognition influence parameters and corresponding sample anomaly recognition results; wherein the fistula abnormity identification influence parameters comprise fistula tremor signals and blood flow and / or blood vessel diameter; and training a preset model based on the plurality of sample data to obtain a fistula anomaly recognition model. According to the method, the fistula tremor signal, the blood flow and / or the blood vessel diameter and the corresponding sample anomaly recognition result are jointly used as the sample data to train the model, the accuracy of the fistula anomaly recognition model is improved, anomaly recognition can be performed on the fistula in real time, accurate evaluation about the internal arteriovenous fistula blood vessel function is provided for doctors, and the accuracy of the fistula anomaly recognition model is improved. Therefore, various complications of internal arteriovenous fistula can be timely and accurately treated, and the safety of a patient is guaranteed.

The application belongs to the technical field of medicine, and particularly relates to a muscone derivative, a preparation method and application thereof. The muscone derivative cyclopentadecanedione monoxime has obvious advantages over muscone and other derivatives in improving the MCAO rat mNSS score, microcirculation blood flow, reducing the cerebral infarction rate, the cortical and hippocampal neuron necrosis rate, and the brain water content, and increasing the SOD and CAT contents of the rat brain tissue which are abnormally reduced due to ischemia, and is a potential effective drug for cerebral ischemia-reperfusion injury.

In the present invention, a control unit (90) of an extracorporeal circulation device (1) capable of ensuring an ideal blood flow rate for a patient when performing VA-ECMO comprises: a calculation unit (91) that calculates an ideal flow rate and pump head pressure from patient-specific information; and a transmission unit (92) that transmits, to a fluid replacement device (70) for performing fluid replacement, water amount data obtained through measurement by a measurement device (80) for measuring the water amount of the patient. The control unit (90) gives a fluid replacement instruction to the fluid replacement device (70) via the transmission unit (92) on the basis of the pressure of the inside of a blood circuit (20) measured by pressure measurement units (45, 46), the flow rate of the inside of the blood circuit (20) measured by a flow rate measurement unit (47), and the water amount data obtained through measurement by the measurement device (80).

This application provides a medical image processing method and system. The method includes: acquiring vascular image volume data from photon-counting computed tomography scans of a target region; based on the vascular image volume data, performing skeletonization processing on the vascular network, extracting multiple skeleton points in the vascular network, and forming a vascular centerline network according to the connection relationships between the skeleton points; identifying endpoints and bifurcation points from the vascular centerline network, thereby dividing the vascular centerline network into several continuous and unbifuzzy vascular segments, and constructing a vascular centerline diagram structure based on each vascular segment; establishing and solving a blood flow analysis model based on the vascular centerline diagram structure to obtain the blood flow analysis results of the vascular network; wherein, the blood flow analysis results include the blood flow rate and / or pressure difference between the two ends of each vascular segment. This application improves the accuracy of the blood flow analysis results.

This invention discloses a real-time visualization monitoring device for microcirculation blood flow, comprising a deep signal acquisition module, a blood flow dynamic acquisition module, an active calibration module, a signal extraction module, and a visualization display module. The deep signal acquisition module acquires mixed light signals from the target tissue region and extracts the signal amplitude. The blood flow dynamic acquisition module acquires a sequence of original light intensity images modulated by ultrasound. The active calibration module obtains the static interference coefficient. The signal extraction module calculates the deep microcirculation blood flow index Q based on a built-in standard reference parameter set. The visualization display module combines a pseudo-color blood flow map with an eschar morphology image to generate a fused image. This invention effectively removes interference from strong scattered light from the surface layer, stably acquires true information about deep microcirculation, and effectively suppresses the artificially high influence of static noise.

A system for regulating blood flow in extracorporeal circulation, and including a blood reservoir to receive blood from a patient, an oxygenator to condition the blood, a centrifugal pump to pump the blood from the blood reservoir to the oxygenator and back to the patient, an electronic remote clamp to regulate flow of the blood, and a controller to operate in a flow control mode and a speed control mode. The controller includes an operational element to set a blood flow value in the flow control mode and to set a speed of the centrifugal pump in the speed control mode. The controller to automatically switch between the flow control mode and the speed control mode in response to one or more trigger conditions and to automatically switch between the speed control mode and the flow control mode in response to opening the electronic remote clamp.

The invention discloses a method for determining hemodynamic parameters, an ultrasonic device and a computer storage medium. The method comprises: emitting an ultrasound beam along at least two directions including a target region of a blood vessel; receiving an ultrasonic echo to obtain an ultrasonic echo signal; determining a velocity component of the velocity of the blood flow in each of the at least two directions according to the ultrasonic echo signal; determining the vector velocity of the blood flow in the blood vessel according to each velocity component; determining a change function of the cross-sectional area of the blood vessel along with time; and determining the blood flow in unit time according to the change function of the cross section area along with time and the vector speed. Visibly, in the process of calculating hemodynamic parameters such as blood flow and blood vessel wall shear stress, the change of the blood vessel cross section area and the change of the blood vessel wall position caused by the change of the blood vessel diameter are considered; therefore, the calculated hemodynamic parameters such as the blood flow volume and the blood vessel wall shear stress are more accurate.

A method and apparatus of automatically locating in an image of a blood vessel the lumen boundary at a position in the vessel and from that measuring the diameter of the vessel. From the diameter of the vessel and estimated blood flow rate, a number of clinically significant physiological parameters are then determined and various user displays of interest generated. One use of these images and parameters is to aid the clinician in the placement of a stent. The system, in one embodiment, uses these measurements to allow the clinician to simulate the placement of a stent and to determine the effect of the placement. In addition, from these patient parameters various patient treatments are then performed.

The present invention relates to a cerebral blood flow augmenter containing isomaltulose as an active ingredient.

The invention discloses a myocardial perfusion quantitative evaluation method. The method comprises the following steps: acquiring an X-ray angiography image target sequence and a computed tomography angiography image of a target blood vessel; determining the volume of a target blood vessel of each X-ray radiography image in the X-ray radiography image target sequence, obtaining the maximum volume and the minimum volume of the target blood vessel from the beginning of filling to the end of filling, and further determining a blood flow volume, and recording the blood flow volume as an initial blood flow volume; according to the computed tomography angiography image, determining the mass or volume of the myocardial area perfused by the target blood vessel to obtain the mass or volume of the target myocardial; carrying out image fusion, and further determining the distribution condition of the target blood vessel on the myocardium; determining target blood flow corresponding to the target blood vessels according to the initial blood flow and the distribution condition of the target blood vessels on the myocardium, and further calculating a quantitative myocardial perfusion value. The method can accurately obtain the quantitative myocardial perfusion value. The invention further discloses a myocardial perfusion quantitative evaluation device, electronic equipment and a storage medium.

The utility model discloses a limb pressure sleeve capable of being used for cold and hot compress, which comprises a pressure sleeve body, an air pipe arranged in the pressure sleeve body, a plurality of air bags symmetrically arranged on one side face of the pressure sleeve body, a contact layer arranged on one side face of the pressure sleeve body, a heating film arranged between the contact layer and the pressure sleeve body, and a cable arranged in the pressure sleeve body. A plurality of notches are symmetrically formed in one side face of the contact layer, a storage bag is arranged on one side face of the contact layer and located among the notches, and a second hook-and-loop fastener thorn face is arranged on one side face of the inner wall of the storage bag. The heating film is heated through power supply of the cable, the heating film is a carbon nano tube / TPU composite film, the heating film is started to heat the legs, and heating can enable local blood vessels to expand, increase blood flow, improve the conveying efficiency of oxygen and nutrient substances, accelerate discharge of metabolic waste, reduce blood viscosity and reduce blood flow resistance, so that the legs are protected from being damaged. The pharmaceutical composition is of clinical significance to patients with hyperlipidemia or diabetes mellitus.

The application discloses a diving decompression sickness dynamic prediction and risk assessment system of multi-tissue parallel computation, relates to the fields of diving medicine, high-pressure medicine and human physiology modeling, and comprises a tissue unit planning module, a central blood circulation and coupling module and a model calculation and risk assessment module. The system divides a human body into a plurality of core physiological tissue units, and plans each tissue unit as a hybrid model composed of three sub-units of "fast-middle-slow". Then, the system simulates a human circulatory system by defining cardiac output, arterial blood inert gas partial pressure and dynamically distributing blood flow according to the tissue type, so as to construct a simulation model. Finally, according to the environmental pressure-time profile corresponding to a diving plan and the breathing gas composition, the simulation model is used to parallelly calculate the inert gas tension of all tissue units and sub-units, so as to be used for dynamic prediction and risk assessment of decompression sickness. The application provides a higher safety margin for saturation diving and repeated diving.

The invention discloses a control method, device and system of a ventricular assist system. The method comprises the steps that a first pressure difference between the two ends of a catheter assembly and a first motor parameter of a blood pumping motor under the condition of preset blood pumping flow are obtained; the actual blood pumping flow of a blood pumping motor is determined based on the first pressure difference and the preset blood pumping flow; correcting the preset blood pumping flow according to the actual blood pumping flow and the heart blood pumping flow of a target object to obtain a target blood pumping flow; adjusting the first motor parameter according to the target pump blood flow to obtain a target motor parameter; and controlling a blood pumping assembly to operate according to the target motor parameters. According to the embodiment of the invention, the operation parameters of the blood pumping motor can be adjusted in real time according to the blood pumping capacity, so that the response speed, stability and robustness of the blood pumping motor are improved, and the threat of the blood pumping motor to the life of a patient is reduced.

The invention belongs to the technical field of medical instruments, and provides a control module and device for dynamic blood flow regulation of a left ventricular assist device.A processor in the control module circularly executes the steps that motion data, the current heart rate and the current blood pressure of a patient and the actual blood flow in a blood pump blood flow channel are obtained; extracting motion features from the motion data of the patient, and inputting the motion features to a motion classification model to obtain a motion mode; determining a motion intensity index of the patient based on the motion pattern and the current heart rate; using a first flow model to obtain a basic blood flow based on the exercise intensity index of the patient; obtaining a target blood flow based on the current heart rate, the current blood pressure and the basic blood flow of the patient by using a flow correction model; and determining a target driving current of a stator coil of the blood pump based on the actual blood flow and the target blood flow by adopting a preset control algorithm. The pump speed is automatically adjusted according to the activity state (such as movement and sleep) of the patient, so that cardiac output supports adaptation to the patient.

The invention relates to the technical field of blood vessel models, and particularly discloses a convenient-to-operate blood vessel model for nursing teaching training, which comprises a mounting seat and a puncture needle, and further comprises a simulation assembly arranged on the upper side of the mounting seat and used for simulating puncture of a blood vessel and collection of blood in the blood vessel; through the simulation assembly, simulation training can be conducted on blood vessel puncture and blood collection, through the regulation and control assembly, the simulation assembly can conduct random simulation on blood vessels with different thicknesses and blood flow, and through the control assembly, according to the puncture pressure of a puncture needle, on the basis of the blood vessel diameter and the blood flow simulated by the simulation assembly, the blood vessel diameter and the blood flow can be simulated by the simulation assembly. And the change of the blood vessel diameter and the blood flow is automatically adjusted to improve the authenticity of simulation.

A renal failure blood therapy system includes a memory device storing a therapy target for a patient. The system also includes a processor configured to receive the therapy target for the patient, receive a desired solute concentration for the patient, and apply the therapy target and the desired solute concentration as inputs to an optimization routine. The processor is also configured to execute the optimization routine to determine at least one dialysis therapy prescription specifying at least a dialysis therapy duration, a dialysis therapy frequency, and at least one of a dialysis therapy blood flow rate or a dialysis therapy dialysate flow rate. The processor is further configured to display the at least one dialysis therapy prescription for confirmation or selection by a clinician and transmit the selected or confirmed dialysis therapy prescription to a dialysis machine for a subsequent dialysis treatment for the patient.

A system for calculating cardiac output of a patient on an extracorporeal blood oxygenation circuit, such as veno-venous extracorporeal membrane oxygenation, includes determining (i) a first arterial carbon dioxide content or surrogate and (ii) a first carbon dioxide content or surrogate in the blood delivered to the patient after passing the oxygenator corresponding to the first removal rate of carbon dioxide from the blood; establishing a second removal rate of carbon dioxide from the blood in the oxygenator in the extracorporeal blood oxygenation circuit; determining (i) a second arterial carbon dioxide content or surrogate and (ii) a second carbon dioxide content or surrogate in the blood delivered to the patient after passing the oxygenator corresponding to the second removal rate of carbon dioxide from the blood; and calculating a cardiac output of the patient corresponding to a blood flow rate through the extracorporeal blood oxygenation circuit, the first arterial carbon dioxide content or surrogate, the first carbon dioxide content or surrogate in the blood delivered to the patient after passing the oxygenator corresponding to the first removal rate of carbon dioxide from the blood; the second arterial carbon dioxide content or surrogate and the second carbon dioxide content or surrogate in the blood delivered to the patient after passing the oxygenator corresponding to the second removal rate of carbon dioxide from the blood.

The utility model discloses an internal fistula exerciser, which belongs to the technical field of medical instruments and comprises a palm protector, one end of the palm protector is rotatably connected with four first joints, one end of each first joint is rotatably connected with a movement ring, the upper end of the palm protector is connected with an elastic component, the inside of the elastic component is connected with a reset spring, and a stabilizing pad is mounted below the palm protector. One end, far away from the palm protector, of the first joint is rotatably connected with a second joint and a third joint, and the outer wall of the lower end of each joint is fixedly connected with a fingerstall. The elastic force generated by the reset spring is used as the acting force for pulling the movement ring to reset, so that the fingers exerting the force are resisted, and through repeated exerting of the force by the fingers, hand fist clenching and loosening actions are simulated, the blood circulation of internal fistula blood vessels is promoted, the blood vessels are expanded, the elasticity of the blood vessel walls is increased, and the blood flow volume and maturity of internal fistula are improved.

The present teaching provides devices and methods for treating heart disease by normalizing elevated blood pressure in the left and right atria of a heart. Various embodiments of the devices allow left-to-right blood flow through their flow elements. The flow element of the device is designed to self-adjust the amount of blood flow in response to the left atrial pressure fluctuation.

The invention discloses a dairy cow oestrus monitoring method and device. The method comprises the following steps: A, acquiring a reflected light intensity value caused by the blood flow change of the nasal septum part of the dairy cow within a first time interval by using an infrared light sensor; b, preprocessing the intensity value of the reflected light in the first time interval; c, calculating a heart rate value by utilizing a preprocessing result; d, the average heart rate value is calculated within a second time interval, the second time interval comprises a plurality of first time intervals, and the average heart rate value is uploaded to the server; e, after a third time interval, collecting and calculating the average heart rate value of the next second time interval again. The dairy cow oestrus monitoring method and device have the advantages of being high in monitoring precision, timely and accurate.

A method and apparatus of automatically locating in an image of a blood vessel the lumen boundary at a position in the vessel and from that measuring the diameter of the vessel. From the diameter of the vessel and estimated blood flow rate, a number of clinically significant physiological parameters are then determined and various user displays of interest generated. One use of these images and parameters is to aid the clinician in the placement of a stent. The system, in one embodiment, uses these measurements to allow the clinician to simulate the placement of a stent and to determine the effect of the placement. In addition, from these patient parameters various patient treatments are then performed.

The application discloses a kind of based on flexible ultrasonic Doppler and AI blood vessel tracking blood flow noninvasive monitoring device, belong to intelligent medical monitoring field.The device includes: flexible ultrasonic Doppler sensor, for attaching body surface signal acquisition;Processing unit and the artificial intelligence analysis module in it, for automatic identification tracking blood vessel and calculate its cross-sectional area and blood flow velocity, and then obtain real-time blood flow;And optional pressure adaptive stabilization module, for dynamic adjustment of adhering pressure according to signal quality to maintain monitoring stability.The application realizes the continuous, noninvasive, automatic monitoring of arterial blood flow, with the advantages of high precision, strong anti-interference, convenient for clinical integration, suitable for perioperative period and critical patient hemodynamic management.

This disclosure relates to a method, device, and system used for identifying and treating responders to external nerve stimulation via a combination of a skin electrode assembly and a functional near-infrared spectroscopy (fNIRS) device. More specifically, this specification discloses a method for cutaneous stimulation of the trigeminal nerve, occipital nerve, vagus nerve, facial nerve and / or any of their branches, and a method for measuring cerebral blood flow in a target brain region.

The invention provides a traditional Chinese medicine composition for treating heart failure and a preparation method of the traditional Chinese medicine composition. The traditional Chinese medicine composition is prepared from the following components: 1-12 parts of rohdea japonica, 1-12 parts of codonopsis pilosula, 1-12 parts of astragalus membranaceus, 1-12 parts of cassia twig, 1-8 parts of bighead atractylodes rhizome, 1-12 parts of poria cocos, 1-12 parts of radix ophiopogonis, 2-14 parts of semen lepidii, 1-10 parts of radix aconiti lateralis preparata, 1-10 parts of schisandra chinensis, 1-12 parts of hairyvein agrimony, 1-10 parts of pseudo-ginseng, 1-12 parts of epimedium, 1-12 parts of leonurus, 1-10 parts of ligusticum wallichii, 2-14 parts of salvia miltiorrhiza, 2-12 parts of radix sophorae flavescentis and 1-8 parts of liquorice. The traditional Chinese medicine composition can enhance myocardial contractility, increase coronary artery blood flow volume, protect myocardial cells, improve heart functions, obviously improve the heart functions and left ventricular remodeling, discharge liquid retained at the time of heart failure, relieve the pre-load of the heart and relieve edema; load during cardiac contraction is reduced, and excessive work of the heart is avoided.