142 results about "Spect imaging" patented technology

Disclosed in the present application are a calibration apparatus, a calibration method, a positioning system, and a laser beam verification motif. The calibration apparatus comprises at least two optical path channels and at least two imaging assemblies, wherein each optical path channel runs through the calibration apparatus, and the optical path channel is used for rays to pass through; the two optical path channels intersect with each other, and the point of intersection of the two optical path channels is the central point of the calibration apparatus; each imaging assembly comprises two imaging surfaces, and the two imaging surfaces are arranged at two opposite ends of the same optical path channel; each imaging surface is provided with a marking portion, the marking portion is provided with a central marking point, and the central marking point is located in an extending direction of the optical path channel; and a connecting line of the central marking points of the two imaging surfaces in one imaging assembly runs through the central point of the calibration apparatus. The calibration apparatus of the present application is configured to acquire a pair of image information in a one-step imaging operation, so as to facilitate the comparison of the pair of image information, thereby adjusting the position offset of an imaging device.

The invention relates to the field of heart nuclear medicine, in particular to a technical method for carrying out myocardial blood flow quantitative analysis through dynamic SPECT imaging of a boric acid 99mTc labeled single-photon SPECT imaging agent, image processing, image correction and myocardial blood flow quantitative calculation, and the technical method is used for generating a dynamic bull's-eye map and a left heart blood pool time activity curve. The method provided by the invention can be used for correcting right heart blood pool overflow interference and myocardial uptake residue interference, quantifying myocardial blood flow and improving fitting operation efficiency, can also be used for establishing a myocardial blood flow volume diagram, and is applied to more intuitively evaluating the resting blood flow, the load blood flow and the high and low areas of the blood flow reserve of the whole myocardial and blood vessel partition. The method provided by the invention can solve the technical problem of myocardial blood flow quantitative analysis by dynamic SPECT imaging of the boric acid 99mTc labeled single-photon SPECT imaging agent and the application problem of the dynamic SPECT imaging of the boric acid 99mTc labeled single-photon SPECT imaging agent.

The invention discloses a time domain point-by-point imaging method, system and device for receiving and transmitting synthetic aperture sonar, and the method comprises the steps: calculating the synthetic aperture length and synthetic aperture time for any pixel in an imaging region; calculating the distance between the sonar and the pixel at the moment of transmitting the signal, and calculating the distance between the sonar and the pixel at the moment of receiving the signal to obtain an accurate two-way slant range process; calculating a reference echo signal corresponding to the pixel according to a two-way slant range process and related parameters of the signal; carrying out range-to-frequency domain conversion on the actually measured echo signal, carrying out range-to-frequency domain conversion on the reference echo signal, and carrying out conjugate multiplication processing on a conversion result; coherent accumulation is carried out on all conjugate multiplication results, and the result is used as an imaging result of the pixel; and for other pixels in the imaging area, repeatedly executing the steps to obtain imaging results of all pixels in the whole imaging area.

The invention relates to the technical field of small animal imaging, and particularly discloses a bimodal small animal molecular image imaging device which comprises a rack; the rotating bracket is rotationally mounted on the rack; the rotating assembly is installed on the rack and used for driving the rotating support to rotate relative to the rack; the CT imaging assembly is mounted on one side of the rotating bracket; the SPECT imaging assembly is installed on the other side of the rotating support, and the imaging center of the SPECT imaging assembly and the imaging center of the CT imaging assembly are coaxial with the rotating axis of the rotating support; the animal bed assembly is installed on the rack and used for bearing a small animal to be imaged and driving the small animal to be imaged to move towards or away from the rotating support along the rotating shaft of the rotating support; the method can effectively solve the problems of registration error, attenuation correction failure, image fusion quality reduction and quantitative analysis misalignment when the SPECT image and the CT image are fused due to alignment error of the SPECT imaging assembly and the CT imaging assembly.

Systems and techniques are described herein for foveated imaging. For instance, a method for foveated imaging is provided. The method may include determining a first region of interest within a first image based on a gaze of a user relative to the first image; clustering pixels of the first image into a one or more clusters of pixels based on a comparison of one or more characteristics of pixels of the first image; identifying a cluster of pixels from among the one or more clusters of pixels based on an intersection over union of the first region of interest and the cluster of pixels; generating a second region of interest based on the first region of interest and the cluster of pixels; and capturing a second image based on the second region of interest.

The invention relates to a low-dose SPECT image reconstruction method and system. The method comprises the following steps: acquiring a plurality of projection images corresponding to a plurality of scanning angles when a target part of a patient is subjected to SPECT imaging scanning; converting the plurality of projection drawings into a plurality of first chordal diagrams, and inputting the plurality of first chordal diagrams into an image reconstruction model to obtain a plurality of second chordal diagrams; wherein the image reconstruction model is obtained by performing model training on a mask auto-encoder model MAE based on a plurality of sample chordal diagrams, a three-dimensional encoder and a three-dimensional decoder are adopted as an encoder and a decoder of the mask auto-encoder model MAE, and the plurality of sample chordal diagrams are obtained by processing a plurality of sample projection diagrams; and reconstructing based on the plurality of second chordal diagrams to obtain a fault diagram of the target part.

In emission imaging, one, two, or a few topograms without a full CT scan are used to localize, such as through triangulation, and / or generate an attenuation map, such as based on model fitting. A limited radiation exposure, rather than a longer, larger full CT exposure, is needed to localize and / or provide attenuation correction for emission imaging, such as cardiac SPECT imaging.

A computer-implemented method is provided for improving image quality. The method comprises: (a) acquiring, using single-photon emission computed tomography (SPECT), a first medical image of a subject, the first medical image is acquired with an acceleration scheme; (b) combining the medical image with a second medical image acquired using computed tomography (CT) to generate an input image; and selecting a deep learning network model to apply to the input image based at least in part on the acceleration scheme and outputting an enhanced medical image.

The invention provides a circuit board defect detection method and system based on deep learning, and the method comprises the steps: firstly obtaining a layered image set of a to-be-detected circuit board, which comprises a welding spot imaging layer, a line imaging layer and an element imaging layer; calling a pre-trained circuit board defect hierarchical detection model, inputting the hierarchical image set into a model defect pre-association layer, and generating a hierarchical defect association map which marks the position mapping relation of the same defect in different imaging layers; on the basis of the layered defect correlation map, extracting defect area exclusive features of each imaging layer to form a layered exclusive defect feature set, and inputting a model hierarchical feature enhancement layer to generate a hierarchical enhanced defect feature set. And finally, calling the model scene adaptive classification layer to carry out defect type matching, and generating a circuit board defect detection report containing defect types, hierarchical positions and association relationships in combination with the position mapping relationship, so that the circuit board defects can be comprehensively and accurately detected, and the detection efficiency and quality are improved.

Systems and techniques are described herein for foveated imaging. For instance, a method for foveated imaging is provided. The method may include determining a first region of interest within a first image based on a gaze of a user relative to the first image; clustering pixels of the first image into a one or more clusters of pixels based on a comparison of one or more characteristics of pixels of the first image; identifying a cluster of pixels from among the one or more clusters of pixels based on an intersection over union of the first region of interest and the cluster of pixels; generating a second region of interest based on the first region of interest and the cluster of pixels; and capturing a second image based on the second region of interest.

The invention discloses an imaging display method and system for head-mounted display equipment, and relates to the technical field of display, and the system comprises an imaging display preparation module and an imaging display adjustment module. According to the method, the biological modeling of the target user is constructed, optimization is automatically carried out according to the vision condition, the head movement habit and the color preference of the user, and the display effect and the comfort degree are improved; by dividing the display screen and dynamically adjusting the display quality of the small area according to the sight focus point of the user, the highest definition of the core area can be always kept, and meanwhile, the display quality is properly reduced in the transition area and the edge area, so that the display effect and computing resources are balanced; by predicting the sight focus point and performing key imaging judgment, the equipment can position the visual attention area of the user in real time and optimize the displayed key area.

The invention discloses a rapid optimization method and system for an unmanned aerial vehicle to get close to a photographing viewpoint, and relates to the technical field of photographing viewpoint optimization. A plurality of photographing targets of the unmanned aerial vehicle on a flight path are set, and the unmanned aerial vehicle is started to fly on the flight path; loading a regional three-dimensional map of a corresponding photographing target on a flight path through which the unmanned aerial vehicle passes, establishing a corresponding viewpoint evaluation model according to the regional three-dimensional map loaded at the photographing target, and analyzing a viewpoint imaging index of the unmanned aerial vehicle to the corresponding photographing target by the viewpoint evaluation model; the state information of the unmanned aerial vehicle in the flight process is obtained in real time, the state information of the unmanned aerial vehicle is transmitted back to the unmanned aerial vehicle operation end, and whether viewpoint optimization at the corresponding photographing target is carried out or not is determined according to the state information of the unmanned aerial vehicle obtained in real time and the viewpoint imaging index of the viewpoint evaluation model for the photographing target. According to the invention, on-demand optimization of shooting viewpoints is realized, and the optimization efficiency, the optimization precision and the imaging quality during shooting of the unmanned aerial vehicle are improved.

The invention discloses an iron-based metal nano diagnosis and treatment agent as well as a preparation method and application thereof. The iron-based metal nano diagnosis and treatment agent comprises an iron-based metal nano material and a diagnosis and treatment agent loaded with therapeutic nuclide 177Lu and / or a micromolecular chemotherapeutic drug F16. The iron-based metal nano diagnosis and treatment agent contains an iron element, can be used for MRI imaging and can induce tumor ferroptosis at the same time, radionuclide 177Lu can emit gamma rays for SPECT imaging and can emit beta rays for tumor internal radiotherapy, tumor mitochondria targeting small molecule medicine F16 has the fluorescence characteristic and can be used for tumor real-time fluorescence imaging, and the application range is wide. Meanwhile, a mitochondrial targeting tumor killing effect is achieved. Therefore, the iron-based metal nano diagnosis and treatment agent disclosed by the invention can realize comprehensive collaborative treatment of intratumor radiotherapy, targeted chemotherapy and ferroptosis under the guidance of MRI (Magnetic Resonance Imaging), SPECT (Single Photon Emission Computed Tomography) and multi-mode imaging of fluorescence imaging, and improves the precise diagnosis and treatment of tumors.

This application relates to a SPECT imaging system, imaging method, and SPECT imaging device. The SPECT imaging system includes multiple imaging modules and a data integration module. Each imaging module scans and images a local area of ​​the object under test, obtaining local imaging data. The data integration module is communicatively connected to the multiple imaging modules and integrates the multiple local imaging data to obtain a complete image. Each imaging module in this application can scan and image a local area of ​​the object under test, thereby obtaining corresponding local imaging data. Simultaneously, the data integration module integrates the multiple local imaging data to obtain a complete image. Since each imaging module includes a motion control unit and a probe, their scanning processes are relatively independent. When multiple areas need to be scanned, multiple imaging modules can perform scanning simultaneously, thus enabling parallel scanning of the object under test and improving scanning efficiency.

The invention relates to a technetium [99mTc]-labeled deuterated tropane derivative and application thereof, and belongs to the technical field of nuclear medicine. The invention provides a technetium [99mTc]-labeled deuterated tropane derivative, which can be specifically combined with a dopamine transporter, and can be used for preparing the technetium [99mTc]-labeled deuterated tropane derivative. The technetium [99mTc]-labeled deuterated tropane derivative has the advantages of good affinity to a dopamine transporter, high radioactive uptake of a target region (striatum) in a brain and high target / background ratio, and has an extremely high application prospect in the aspect of SPECT (Single Photon Emission Computed Tomography) imaging of the dopamine transporter.

The present invention relates to the field of wafer defect detection, and provides a measurement system and method for centering a motion platform. The system includes a motion platform, which includes a Y-axis motion platform and a Theta rotation platform. The Y-axis motion platform moves linearly along the Y-axis direction, and the Theta rotation platform rotates around the rotation center point O. An incident optical path that focuses a light spot on the wafer to form a scanning center point O<supgt;,< / supgt>. An imaging optical path that collects the energy of scattered light or reflected light on the wafer to form a scanning image. And a wafer arranged on the Theta rotation platform, with a characteristic pattern provided on the wafer. The offset between the rotation center point O and the scanning center point O<supgt;,< / supgt> is determined by scanning the characteristic pattern and calculating coordinates, and the motion platform is adjusted to align the rotation center point O with the scanning center point O<supgt;,< / supgt>. The present invention can achieve the alignment of the optical scanning point and the center point of the rotation platform in the wafer defect detection system, effectively improving the accuracy of the wafer defect detection result.

A method includes accumulating counts for each pixel in a set of pixels of one or more gamma cameras of a SPECT imaging system from a plurality of imaging examinations and each energy peak of each isotope used in the plurality of imaging examinations to produce an energy spectrum for each of the pixels at each of the energy peaks of each of the isotopes, determining, for the pixels and for the energy peaks, an energy calibration factor that converts an energy detected by each of the pixels to an energy of a corresponding energy peak and populating an energy map with the factors, and determining, for the pixels and for the energy peaks, a uniformity calibration factor that converts a number of counts detected by each of the pixels to a predetermined number of counts for a corresponding energy peak and populating a uniformity map with the factors.

Compounds for targeting and agents for imaging, prostate-specific membrane antigen (PSMA) are disclosed. Methods of synthesizing compounds and imaging agents, as well as methods for imaging PSMA are also disclosed. The imaging agents disclosed are suitable for PET and SPECT imaging.

A method for relaxation time determination includes delivering a series of radio frequency (RF) pulses in a sequence to a specimen having a magnetic resonance spin system. The pulses are separated by equal time intervals and the sequence has a duration comparable or greater than a spin-lattice relaxation time for the spin system. The method includes receiving a response after each RF pulse in the series. The response includes a free induction decay and spin echoes. The method includes generating a series of single point imaging (SPI) images from each response. Each SPI image of the series corresponds to an RF pulse in the series. The method includes converting SPI images to a spin-spin relaxation map and a spin-lattice relaxation map.

The utility model discloses a sub-band imaging device, relates to the technical field of imaging, and aims to solve the problems that pixel points are smaller and smaller and RGB (Red, Green, Blue) is larger and larger in process difficulty due to the fact that the RGB is on the same photosensitive chip and under different light intensities, the pixel points are smaller and smaller, and the RGB is larger and smaller in process difficulty due to the fact that the RGB is on the same photosensitive chip. When the light intensity difference is large, the dark part cannot be seen clearly or the bright part is exposed excessively, so that the device comprises a device body, a light inlet is formed in the device body, multiple sets of light outlets are formed in the bottom of the device body, and a primary color separation structure is arranged in the device body. The output end of the primary color separation structure is provided with a sensing structure. According to the invention, the pixels can be effectively increased without increasing the pixels; meanwhile, the situation that imaging cannot be achieved due to light intensity differences is avoided through light imaging of different wavebands, and the imaging dynamic range is greatly widened; and the imaging quality is improved.

The utility model provides a naked eye aerial imaging device of a culture gallery, the top of the culture gallery is provided with a naked eye 3D display module used for displaying 3D images, the naked eye 3D display module comprises a first multi-point naked eye 3D display and a second multi-point naked eye 3D display which are mutually symmetrical; the negative refractive index optical element is used for respectively refracting 3D images formed by the first multi-point naked eye 3D display and the second multi-point naked eye 3D display to different 3D viewpoint positions and forming three-dimensional images at two positions in the air, the negative refractive index optical element comprises a first transparent substrate, a first optical waveguide layer, a second optical waveguide layer and a second transparent substrate which are attached in sequence. And the two multi-view imaging devices are respectively used for displaying the three-dimensional images at two positions, the two multi-view imaging devices are symmetrically arranged, and the two multi-view imaging devices and the negative refractive index optical element are arranged at an angle, so that a screen at the back can be hidden, and the three-dimensional display device looks more scientific and fantastic.

The application discloses a time-domain point-by-point imaging method, system and device of a transceiver combined synthetic aperture sonar, and the time-domain point-by-point imaging method comprises the following steps: for any pixel in an imaging area, calculating a synthetic aperture length and a synthetic aperture time; calculating a distance between a sonar at a signal transmitting time and the pixel, and calculating a distance between a sonar at a signal receiving time and the pixel to obtain an accurate two-way slant range history; according to the two-way slant range history and relevant parameters of the signal, calculating a reference echo signal corresponding to the pixel; performing distance domain transformation on a measured echo signal and a reference echo signal, and performing conjugate multiplication processing on the transformed results; coherently accumulating all the conjugate multiplication results as an imaging result of the pixel; and repeating the above steps for other pixels in the imaging area to obtain imaging results of all the pixels in the entire imaging area.

The invention provides a detector of an SPECT imaging system, the SPECT imaging system and an SPECT imaging method. The detector of the SPECT imaging system comprises a plurality of detector units, and the plurality of detector units are arranged in a first direction; each detector unit comprises a plurality of detector modules arranged in a second direction, the second direction is perpendicular to the first direction, each detector module comprises a scintillation crystal array, an SiPM detector array and a preprocessing device which are sequentially arranged in a third direction, and the third direction, the first direction and the second direction are perpendicular to one another; the scintillation crystal array comprises a plurality of scintillation crystal blocks arranged in an array, the SiPM detector array comprises a plurality of SiPM detector pixels arranged in an array, and the scintillation crystal blocks and the SiPM detector pixels are arranged in a one-to-one correspondence manner. According to the detector, the spatial uniformity is remarkably improved, and the imaging quality is further improved.

The invention discloses an SPECT imaging device, an SPECT imaging system and a diagnosis combination. The SPECT imaging device comprises a rack and a nuclear detector group. The rack is provided with a through hole for a detected object to pass through. The through hole has a central axis. The nuclear detector group is arranged on the end face of the rack and comprises a plurality of longitudinal detectors arranged on the upper side and the lower side of the central axis and a plurality of transverse detectors arranged on the left side and the right side of the central axis, and the longitudinal detectors are used for obtaining longitudinal images of a detected object; the plurality of transverse detectors are used for acquiring a transverse image of the detected object, and the distance between the longitudinal detector and the central axis is smaller than that between the transverse detectors and the central axis. According to the SPECT imaging device, the collection efficiency is improved, the sensitivity is improved, and the resolution ratio of a detection image is improved.

The present application discloses an imaging device, comprising: a position information acquisition module for obtaining position information of a target organ; an irradiation depth determination module for determining the irradiation depth of imaging rays from a detection point into the interior of a human body based on the position of the detection point and the target detection depth; a light source focus control module for determining the focus information of multiple light sources based on a preset magnification and irradiation depth; an irradiation module for controlling the multiple light sources to generate imaging rays to irradiate the detection point based on the focus information; an imaging module for obtaining first imaging information of a tomographic scan based on a first remaining imaging ray passing through the detected position of the target organ; and obtaining an image of the target organ based on the first imaging information. The imaging device provided in the embodiments of the present application is capable of performing microscopic imaging of a target organ using imaging rays.

Optical system (21) for a metrology system (1) for measuring an object (2) in the form of a lithography mask, - with an object holder (14) for holding the object (2) in an object plane (13), - with a transmissive optical focusing component (11) arranged in the beam path of illumination light (4) between a light source (5) of the metrology system (1) and an object field (12) in the object plane (13), to generate an illumination focus (16) in the beam path of the illumination light (4) after the transmissive optical focusing component (11), - wherein the transmissive optical focusing component (11) has a focal length (f1) that is less than 5 mm, - with a detection device (6) for detecting the illumination light (4) in the beam path after the object field (12), - with an imaging optic (22) for imaging the illumination focus (16) generated by the transmissive optical focusing component (11) into a further illumination focus (16') in the area of ​​the object field (12).

The present invention provides a bivalent bispecific antibody targeting an EGFR and a c-MET and a radioactive label thereof. The research shows that the bivalent bispecific antibody provided by the present invention has good targeting affinity, and an antibody-radionuclide conjugate (taking 177Lu radioactive label as an example) of the bivalent bispecific antibody has an excellent SPECT imaging result, can be continuously accumulated in tumors over time, is more quickly removed in organs such as the liver and normal tissues, and can exhibit lower toxic and side effects. This also indirectly shows that the bivalent bispecific antibody provided by the present invention can clinically exhibit higher safety potential.

Methods and systems are provided for calibrating a single photon emission computed tomography (SPECT) imaging system. In one example, a collimated line source for calibrating a SPECT system comprises a radioactive material aligned along a central axis of the collimated line source and a plurality of collimator plates arranged perpendicularly around the central axis, the collimator plates including a material that substantially absorbs photons striking the collimator plates. The collimator plates may absorb photons emitted by the radioactive material in non-perpendicular directions, which are not used for calibrating the SPECT imaging system, thereby reducing an amount of radiation released in an environment of the SPECT imaging system during calibration. Due to the reduced amount of radiation to which people in the environment are exposed, short time increments between patient examinations may be advantageously used to collect calibration data, reducing an overall amount of time used for calibration.

According to an embodiment, an optical inspection apparatus includes an illumination portion, an imaging portion, and a processor. The illumination portion is configured to irradiate a first object point of an object with a light beam flux at one or more solid angles. The imaging portion is configured to acquire an image of the object according to illumination with the light beam flux. The processor causes the first object point to be irradiated with a light beam flux at a first solid angle by first illumination light, acquires a first captured image of the object with the first illumination light, causes the first object point to be irradiated with light beam fluxes at the third and fourth solid angles by second illumination light, acquires a second captured image of the object with the second illumination light, and acquires information regarding the object by the first and second captured images.

The invention discloses a myocardial amyloidosis quantitative analysis method based on SPECT imaging and related equipment, and relates to the field of wisdom medical device.The method comprises the steps that firstly, three-dimensional SPECT original data of N time phases of a target patient in the cardiac cycle are collected, a mu graph is generated based on low-dose CT for registration and attenuation correction, and a dynamic image is reconstructed; and then an MR structure sequence under synchronous electrocardio gating is obtained, and SPECT and MR space standardization and partial volume effect correction processing are completed. And unifying the cardiac cycle image form through affine and nonlinear transformation, and generating a high-quality enhanced SPECT image. Finally, radioactive counting information is extracted on the basis of three-dimensional segmentation, multiple myocardial quantitative indexes are calculated, comprehensive analysis of myocardial functions is achieved in combination with left ventricular functional parameters, and accurate image support is provided for non-invasive diagnosis and curative effect evaluation of myocardial amyloidosis.