290 results about "Arterial vessel" patented technology

A delivery system for delivery and deployment of a self expanding stent 1 especially in an arterial vessel with a tortuous passageway leading thereto comprises a catheter shaft 9 with a distal sheath 6. An inner core 5 is fixed to a larger diameter outer core 10, the difference in diameter providing an abutment. To deploy the stent 1, the sheath 6 is drawn proximally relative to the inner core 5, the proximal end of the stent 1 is engaged by the abutment and the stent 1 expands as it is uncovered by the sheath 6. The system includes a stabiliser tube 25 to which the inner core 5 is fixed, at least during the deployment of the stent 1.

A device for the removal of clot obstructing the flow of blood through an arterial vessel comprises an elongate member, a clot engaging element and a capture basket. The elongate member extends in use from a point adjacent a target treatment site interior of the patient to a point exterior of the patient. The capture basket comprises a frame and a net, and has an expanded and a collapsed configuration. The clot engaging element comprises a plurality of struts having an expanded and a collapsed configuration. The plurality of struts form a first section and a second section, the first section tapering outward and distally from the elongate member and connected to the second section. The second section comprises a plurality of cells defined by a plurality of struts and arranged around at least a portion of the circumference of an axis substantially parallel to that of the elongate member. The clot engaging element and the capture basket are restrained in the collapsed configuration for delivery to the target site. The clot engaging element is located adjacent the distal end of the elongate member and proximal of the capture basket.

This invention relates to methods and devices providing transmyocardial blood flow or coronary revascularization for the treatment of coronary atherosclerosis and resulting myocardial ischemia by increasing the flow of blood from one or more oxygenated blood sources within the patient to one or more sites selected in the arterial vascular system of the heart using a channel for maintaining and regulating blood flow therebetween. A valved conduit or a self-maintained channel is created between the left ventricle reservoir of oxygenated blood and the coronary artery distal to an area of obstruction by surgical and percutaneous methods. Preferably, the conduit or self-maintained channel integrally regulates the flow of blood between the oxygenated blood source and the site selected in the arterial vascular system of the heart wherein an increase in blood flow is desired.

The invention discloses a noninvasive continuous human body arterial blood pressure measuring method and equipment. The noninvasive continuous human body central arterial blood pressure measuring method comprises the steps as follows: calculating individualization parameters of a to-be-measured person artery blood vessel network model according to acquired pulse wave forms of radial arteries and brachial arteries; calculating radial artery blood pressure systolic pressure, diastolic pressure and blood pressure wave forms according to radial artery pulse wave speeds and artery blood vessel network parameters; calculating ascending aorta-radial artery transfer functions; further calculating central arterial blood pressure. The noninvasive continuous human body central arterial blood pressure measuring equipment consists of a signal processing and analyzing unit, a pulse wave and motion signal acquisition unit worn on the wrist as well as an electro-cardio and motion signal acquisition unit worn in front of the chest. According to the method and the equipment, electrocardiograms, the radial artery blood pressure, the central arterial blood pressure as well as motions and postures are monitored simultaneously, heart rate and electro-cardio morphological parameters are analyzed in various motion states, artery network model parameters and blood pressure parameters, particularly central arterial pressure wave form parameters, are analyzed, and the method and the equipment have great significance for prevention and control on cardiovascular diseases, particularly for prevention and control on high-risk diseases such as the hypertension, the coronary heart disease and the like.

An apparatus and method for stabilization of aneurysm is disclosed. The apparatus comprises an ultraviolet radiation generator for generating UV radiation having a wavelength, strongly absorbed by the DNA and a catheter including means for delivering the ultraviolet radiation to the aneurysm. The distal end of the catheter is placed inside the aneurysm. Stabilization of the aneurysm is achieved by forming a mural arterial thrombus inside the aneurysm. To make irradiation possible, the blood is displaced from the aneurysm by a steady stream of UV radiation transparent fluid. The injury to the endothelium that triggers the thrombus formation is caused by UV radiation delivered to the aneurysm. In several days after intervention the thrombus becomes fully organized, leaving on the inside surface of the aneurysm a thick layer of fibrotic tissue that stabilizes the aneurysm.

A device for protecting cerebral vessels or brain tissue during treatment of a carotid vessel includes a catheter having a distal portion, a proximal portion and a lumen extending therebetween, the catheter including first and second expandable areas for vessel occlusion provided over the length of the catheter. The device further includes an elongate stretching member insertable longitudinally through the lumen of the catheter, the elongate stretching member being configured for stretching at least a portion of the catheter and causing the first and second expandable areas to transition from an expanded state to a collapsed state, and wherein the elongate stretching member is retracted proximally relative to the catheter causes the first and second expandable areas to transition from the collapsed state to a radially, or laterally expanded state.

The invention provides a branched membrane-covered support conveying system comprising a double-layer sheath tube for containing a membrane-covered support and a towing and releasing mechanism for towing and releasing the membrane-covered support from the sheath tube, wherein a support main body and a support branch of the membrane-covered support are movably and integrally arranged in the double-layer sheath tube after being bounded; the support main body is connected with a control guiding part and is towed and released by the control guiding part; and the support branch is towed by a branched guiding part and is connected with the control guiding part, thereby being released by the control guiding part. The invention also provides a method for conveying the branched membrane-covered support into an arterial vessel. The conveying system can effectively ensure that the membrane-covered support is smoothly and safely conveyed into the arterial vessel, and can accurately position the support main body according to the position of a pathological change, especially the position of the support branch, and after positioning, the conveying system can simultaneously or respectively and safely release the support main body and the support branch so that the membrane-covered support can be more widely applied to endovascular exclusions especially relating to branched arterial pathological changes.

The present invention provides a P2Y12 receptor antagonist compound-eluting stent, wherein the stent is coated with one or more P2Y12 receptor antagonist compounds or a pharmaceutically acceptable salt, solvate, or hydrate thereof. When the stent is placed in a narrowed or damaged arterial vessel, a therapeutically effective amount of the P2Y12 receptor antagonist compound is eluted continuously from the stent to the local environment of the stent. The P2Y12 receptor antagonist compound-eluting stents are useful in preventing thrombosis and restenosis, and are effective in inhibiting the contraction of vascular smooth muscle cells, inhibiting cell proliferation, and reducing inflammation.

A pulse diagnostic instrument of the present invention comprises a plurality of probes connected together and aligned laterally in series, with each probe configured for contacting a skin surface of a body limb adjacent an arterial vessel. Each probe includes a pressure sensor configured for sensing a pulse pressure of the arterial vessel and an electrically-driven pressure applicator, mounted to the pressure sensor, and configured for applying an external force through the pressure sensor to apply pressure against the arterial vessel through the skin surface during sensing of the pulse pressure.

An implant assembly is implanted in vivo within a vascular system in which a vessel divides at a furcation into two sub-vessels, each sub-vessel having a diameter smaller than the diameter of said vessel. An implant assembly is released into a vessel such as a pulmonary arterial vessel of a patient. The implant assembly has a diameter smaller than or substantially equal to the inner diameter of the vessel and larger than the inner diameter of each of the sub-vessels. The implant assembly is configured so that it moves downstream within the vessel along with the flow of blood. When the implant assembly reaches a furcation where the vessel divides, the implant assembly is too large and not sufficiently compliant to fit through either of the smaller branch vessels. The implant assembly thus lodges at the furcation, prevented from moving downstream by being too large and stiff to fit into the branch vessels, and prevented from moving upstream by the flow of blood through the arteries. Alternatively, the implant assembly has a diameter greater than a vessel and compliance characteristics such that, upon release, the implant assembly travels down a narrowing vessel until an interference fit is created between the anchor structure and the vessel wall, thereby preventing further distal movement.

The invention discloses a non-invasive central aortic blood pressure measuring method and device. The non-invasive central aortic blood pressure measuring method includes, according to a human artery network model based on viscous fluid mechanics, a method of calculating artery network model personalized parameters of a measured person through measured radial artery and brachial artery pulse wave signals and arm blood pressure values, a method of calculating an ascending aorta-radial artery transfer function and a method of calculating central arterial pressure waveforms through measured central arterial pressures. The non-invasive central aortic blood pressure continuous measuring device comprises a pulse wave signal processing and analysis unit and a radial artery and brachial artery pulse wave signal acquisition unit worn on a wrist. The method is different from an existing general transfer function method, the artery network model parameters of each person to be measured are measured and calculated and the artery network model parameters are numerical characteristics of the cardiovascular system states of the person to be measured with the calculated central arterial pressure waveforms, and the method and device has important meanings in prevention, curing and control of cardiovascular diseases, especially high-risk diseases, such as hypertensions and coronary heart diseases.

An implant assembly is implanted in vivo within a vascular system in which a vessel divides at a furcation into two sub-vessels, each sub-vessel having a diameter smaller than the diameter of said vessel. An implant assembly is released into a vessel such as a pulmonary arterial vessel of a patient. The implant assembly has a diameter smaller than or substantially equal to the inner diameter of the vessel and larger than the inner diameter of each of the sub-vessels. The implant assembly is configured so that it moves downstream within the vessel along with the flow of blood. When the implant assembly reaches a furcation where the vessel divides, the implant assembly is too large and not sufficiently compliant to fit through either of the smaller branch vessels. The implant assembly thus lodges at the furcation, prevented from moving downstream by being too large and stiff to fit into the branch vessels, and prevented from moving upstream by the flow of blood through the arteries. Alternatively, the implant assembly has a diameter greater than a vessel and compliance characteristics such that, upon release, the implant assembly travels down a narrowing vessel until an interference fit is created between the anchor structure and the vessel wall, thereby preventing further distal movement.

The invention belongs to the field of intersection of a computer technology and medical images, and in particular relates to an automatic dividing method of internal and external profiles in the cross section direction of an ultrasound image carotid artery blood vessel. The method specifically comprises the following steps of: selecting the current frame image; manually defining a reference profile point and interpolating to form a reference profile; extrapolating the reference profile to form a first interested area; automatically detecting a carotid artery profile: searching a radial gradient maximum point on a polar coordinate image obtained through conversion in a first interested area as the initial external profile point, estimating the gray probability density distribution in the first interested area by using mixed distribution, carrying out level set evolution to obtain the external profile, interpolating the external profile to form an initial internal profile and carrying out level set evolution to obtain an internal profile. By adopting the method, ultrasound carotid artery images can be effectively divided, and the workload of doctors can be reduced; and besides, the carotid artery internal and external profiles obtained through division in the method can be used for calculating the size of the carotid artery blood vessel wall and providing accurate and effective information for research of carotid atherosclerosis.

The invention discloses an artery blood vessel image model training method, a segmentation method, a device and an electronic device, belonging to the technical field of digital image processing. Theartery blood vessel image model training method comprises the following steps: 1, pre-processing the acquired DSA image to construct an artery blood vessel image database; 2, labeling part of the sample images in the arterial blood vessel image library to construct a labeled sample image set; 3, constructing a convolution depth network and setting parameter of that depth network to generate an initial artery blood vessel segmentation model; 4, training an initial artery blood vessel segmentation model by using a label sample image set to generate an artery blood vessel image segmentation model; 5, further labeling the blood vessel target image obtained by using the artery blood vessel image segmentation model to segment other images except part of the sample images in the artery blood vessel image library, so as to carry out iterative training on the artery blood vessel image segmentation model. The embodiment of the invention can extract target blood vessels from DSA images with highaccuracy.

An inflatable cuff for blood pressure measurement includes a first inflatable bag to press an arterial vessel of a body portion of a living subject for stopping blood flow; a second inflatable bag for sensing a pulse wave propagating along the arterial vessel, which is supported by the inflatable cuff such that the second inflatable bag is located inside a downstream-side portion of the first inflatable bag in the direction of the blood flows; a shielding member disposed between the first inflatable bag and the second inflatable bag so as to prevent an oscillation of the first inflatable bag from propagating to the second inflatable bag; and a slidable separating member disposed between the shielding member and the second inflatable bag so as to prevent generation of a noise caused by a slide contact of the shielding member with the second inflatable bag.

A method and apparatus for treating an acute myocardial infarction is provided. The apparatus comprises an ultrasound catheter that can be inserted into the esophagus to deliver ultrasound energy to the heart and coronary vasculature. The ultrasound energy can enhance the effect of an intravenously administered thrombolytic drug on a blood clot within the coronary vasculature. The ultrasound catheter can have a means for promoting acoustic coupling with the esophagus and a means for preventing or reducing aspiration of fluids into the lungs.

The invention discloses an arteriovenous simulation method and device used for puncture teaching. According to the device, two latex tubes, namely a first latex tube and a second latex tube, are arranged on an emulational arm to respectively simulate an arterial blood vessel and a venous blood vessel, a diaphragm pump is used to extract emulational blood from a liquid storage container, and pumps the emulational blood to the first latex tube; after flowing through the first latex tube, the emulational blood enters the second latex tube through a throttle valve, and finally the emulational blood returns back to the liquid storage container through the second latex tube, so that a simulated blood circulation system is formed; a brushless DC motor is controlled to be started / stopped intermittently to drive the diaphragm pump, so that the first latex tube can shrink and expand intermittently to simulate human pulse beat; after the emulational blood flows through the throttle valve, expansion and shrinkage frequency reduces, even expansion and shrinkage disappear, so that the second latex tube can simulate a human venous blood vessel; when puncture teaching is needed, the two latex tubes on the emulational arm are respectively punctured by an injection syringe needle, so that arterial puncture and venipuncture simulation trainings are realized.

A device and method for treatment of intracranial vasospasm is provided. The device is a microcatheter having a steeply tapered end and is thicker walled, and in a preferred embodiment is braided to provide greater pushability. In order to achieve a thicker walled catheter, in one embodiment, the inner lumen diameter can be reduced, leaving the outer diameter the same while in another embodiment the catheter is larger in outer diameter. In one embodiment, the microcatheter is coated with performance enhancing lubricant, such as a hydrophilic coating. Further, the microcatheter can also be coated with drugs and serve as a drug delivery device, drugs being embedded into vessel intima. In the use of the method of treatment, the device is fed into the smaller arterial vessels in the brain simultaneously dilating arteries of various caliber along the path of the catheter to relieve vasospasm; pharmacological agents can then be delivered by the microcatheter to further effect treatment.

The invention provides a blood vessel model used for simulating blood circulation, which is formed by processing a transparent or semitransparent material according to an aorta of the human body and is designed with a split structure which can be detached. The invention also provides a blood circulation simulation device, which comprises an experimental operation box, a liquid tank, a control main machine connected with the liquid tank for controlling the supply and discharge of simulative blood and the blood vessel model which is arranged in the experimental operation box and is in sealed communication with the liquid tank, wherein the experimental operation tank has an opening for minimally invasive appliance intervention, and the opening can be sealed. The blood vessel model and the blood circulation simulating device effectively solves the problems of high cost, invisible surgical process, difficult artery intervention surgical training and the like of the prior minimally invasive surgical operation exercises. The blood vessel model and the blood circulation simulating device mainly used on occasions such as artery minimally invasive intervention surgical experiments, surgical operation exercises, artery intervention surgery experimental performance tests and the like.

An inflatable cuff for blood pressure measurement includes a first inflatable bag which is inflatable to press an arterial vessel of a body portion of a living subject and stop flow of blood in the arterial vessel which the inflatable cuff is adapted to be wound around the body portion; a second inflatable bag for sensing a pulse wave propagating along the arterial vessel, which is supported by the inflatable cuff such that the second inflatable bag is located inside a downstream-side portion of the first inflatable bag in the direction of the blood flows in the arterial vessel, and which has a dimension as measured in the direction that is smaller than a dimension of the first inflatable bag as measured in said direction; and a fluid-filled bag which is located between the second inflatable bag and the body portion and which is filled with incompressible fluid.

Medical devices for revascularization and methods of their use are disclosed. The medical device includes an actuator portion, an inner tubular body connected to the actuator portion and an outer tubular body connected to the actuator portion. The inner tubular body is disposed within a bore of the outer tubular body. The medical device also includes a guide wire extending through one or more of the actuator portion, inner tubular body and outer tubular body.

The invention discloses a quasi-physiological pulsatile flow environment arterial blood vessel tissue engineering reactor; the reactor includes a liquid storage bottle, a pulsation source, a resistance regulator, a compliance regulator and a blood vessel tissue dynamic culture cavity and is controlled by an industrial control computer; the reactor overcomes the shortcomings that the commonly used arterial blood vessel tissue engineering reactor in the tissue engineering filed can not simulate the blood flow compliance of the arterial blood vessel, flow inertia, flow resistance and other resistance characteristics and can not provide the quasi blood pulsatile flow environment in the artery; the reactor has the following functions that: a. the reactor is used for culturing the tissue engineering arterial blood vessel; b. the reactor is used for simulating the pulsating frequency, pulse waveform, secondary wave, amplitude and time phase of the pulsatile flow of the different arterial blood vessel under the physiological state, simulating the hemodynamics environment of high vessel inner pressure and high shear stress of the arterial blood vessel under the hypertension and other pathological states and simulating the hemodynamics status of the arterial blood vessel during the low shear stress.

The embodiment of the invention provides an establishing method and an establishing device for an artery blood vessel age estimation model, relating to the technical field of cardiovascular disease monitoring. The method comprises the following steps: collecting the reference artery blood vessel age, physiological signals and individual information of sample users; for each sample user, carrying out weighted feature acquiring operation according to the gender, namely, carrying out feature extraction according to the physiological signals and the individual information, carrying out normalization processing on the features, thus obtaining normalization features, calculating the weight coefficient of each feature according to the correlation coefficient of each feature and the reference artery blood vessel age, calculating the weighted feature of each feature according to the normalization feature and the weight coefficient; and by adopting the weighted features and the reference arteryblood vessel age of each sample user as sample data, training a neural network, thus obtaining the artery blood vessel age estimation model. The embodiment of the invention is accurate in estimation and suitable for family medical treatment, and can provide useful physiological parameters for family health.

The invention relates to a method for detecting vessel stenosis based on double interventional pressure sensors. According to the method for detecting the vessel stenosis based on double interventional pressure sensors, the two pressure sensors are guided into a blood vessel (mainly the artery blood vessel) in an interventional mode, and whether stenosis happens to the blood vessel between the two pressure sensors can be judged by measuring the numerical values of the two pressure sensors through calculation.

A system and method for improving the examination of vessel walls through fluid using near infrared (NIR) spectroscopy by employing a parallel measurement where all wavelengths are measured simultaneously. The system and method of the present invention obviates that need to attempt to overcome the motion of a catheter by complex filtering or averaging over time by performing the measurements for each wavelength under identical conditions.

The invention provides a porcine arterial vacuum lyophilization acellular matrix, as well as a preparation method and application thereof. The preparation method of the porcine arterial vacuum freeze-drying acellular matrix comprises the following steps: performing vacuum lyophilization to the porcine arterial blood vessels to obtain the best pore by adopting an optimal pre-freezing velocity; rehydrating the matrix with low-concentration detergent and performing acellular treatment; and lyophilizing the matrix and storing at normal temperature. The matrix has the advantages that the porcine aorta is used as a studying object, and a lyophilized acellular blood vessel with proper porosity, mechanical performance and immunogenicity is produced by virtue of optimized preparation conditions; animal in-vivo experiments prove the practicality of three-dimensional blood vessel clinical vascular transplantation, and experimental basis is provided to further clinical application; the preparation method has extremely low cost, so that precious medical resources reach billions of RMB can be saved assuredly; and experimental basis and guidance are provided to clinical application of tissue engineering arterial blood vessels and optimizing research and development of acellular blood vessels.

The invention relates to the technical field of pelvis and pelvis artery blood vessel tree segmentation, in particular to a deep learning-based pelvis and pelvis artery blood vessel multi-level segmentation method, which is used for solving the problem that an abdomen pelvis and a pelvis artery blood vessel tree cannot be automatically, efficiently and accurately segmented in a multi-resolution CTimage in the prior art. The method comprises the following steps: step 1, preparing and labeling data; 2, preprocessing the data; 3, constructing a first-level segmentation model of the 3D convolutional neural network based on multi-level segmentation; 4, constructing a second-stage segmentation model; 5, training a first-stage segmentation model and a second-stage segmentation model by using thecalibrated data and the synthesized loss function; and 6, performing abdomen information segmentation on the input three-dimensional CT image by using the first-stage segmentation model and the second-stage segmentation model trained in the step 5. According to the method, the abdominal pelvis and the pelvis vascular tree can be automatically, efficiently and accurately segmented in the multi-resolution CT image.

A device and method for monitoring an access to a patient for an extracorporeal blood treatment apparatus with an extracorporeal blood circuit are described, as well as an extracorporeal blood treatment apparatus with a device for monitoring the vascular access. The device and method are based on the monitoring of a characteristic property of the blood, in particular the concentration of haemoglobin in the blood flowing in the arterial blood line of extracorporeal blood circuit I of an extracorporeal blood treatment apparatus A. In the event of an incorrect vascular access, the flow conditions change in the communicating intra- and extracorporeal blood circulation system. These changes in the flow conditions can be detected as a change in the haemoglobin concentration. A disconnection of venous puncture cannula for the patient access is ascertained by a reduction in the haemoglobin concentration in the blood in arterial blood line.

A vascular endothelial reactivity measuring apparatus according to the present invention includes: a blood flow blocking section 2 for blocking blood flow through the arterial blood vessel of an organism; an evaluating section 4 for evaluating the geometric property of the arterial blood vessel or its wall; and a control section 3 for controlling the blood flow blocking section such that the blood flow through the arterial blood vessel is repeatedly blocked and unblocked in at least two iterative blocking / unblocking cycles. During at least a part of a period in which the blood flow through the arterial blood vessel is unblocked, the evaluating section 4 evaluates the geometric property and processes data, representing the geometric property during the partial period, in the iterative blocking / unblocking cycle.