310 results about "Arterial vessel" patented technology

The invention discloses an automatic vein and artery puncture control method, which is used for realizing high-precision puncture through precise control, and comprises the following steps of: after determining to start automatic vein and artery puncture control, collecting a blood vessel ultrasonic image; aiming at the target blood vessel ultrasonic image data, establishing a static artery blood vessel detection model based on a lightweight deep network and a target detection algorithm; the blood vessel detection model is used for detecting and positioning blood vessels; collecting a blood vessel image to be detected and positioned in real time, and obtaining the position and category of the blood vessel based on the trained blood vessel detection model; determining a target blood vessel position based on blood vessel positioning and classification, wherein the target blood vessel position is a puncture target position; planning a puncture path based on the target blood vessel position, including vein puncture path planning and artery puncture path planning; and converting the path and the control parameters based on puncture path planning. The invention further discloses a device and a system, which have low requirements on working environment, can adapt to dynamic environment, are convenient to popularize, reduce puncture difficulty and labor intensity and are portable.

The invention discloses a method and system for sensing health based on a fingertip wearable spectrum sensor and a computer program product, and the method comprises the steps: controlling a spectrum chip to collect characteristic spectrum data corresponding to an artery blood vessel projection region of a user according to a received index monitoring instruction; the characteristic spectrum data is obtained based on emission and reception of one or more light from ultraviolet light to near-infrared light; receiving the characteristic spectrum data sent by the spectrum chip, and calculating a calibration spectrum value based on the characteristic spectrum data; and the calibration spectrum value is sent to the intelligent terminal, so that the intelligent terminal calculates the physiological health index, analyzes and processes the physiological health index, and pushes a personalized adjustment scheme. The fingertip wearing type spectrum sensing glove is convenient to wear, rich characteristic spectrum data can be collected according to user requirements, the intelligent terminal can quickly and accurately calculate various physiological health indexes, the intelligent terminal is not limited to traditional heart rate and blood oxygen monitoring, and the intelligent terminal can further analyze and process the physiological health indexes.

The large-area contact type threaded degradable magnesium alloy aorta blood vessel anastomat comprises a conical inner ring, a conical outer ring and a sleeve outer ring which are sequentially arranged from inside to outside, a blood vessel clamping space is formed between the conical inner ring and the conical outer ring, and the conical outer ring and the sleeve outer ring are in threaded fit. The sleeve outer ring is rotated to adjust the size of the blood vessel clamping space. The blood vessel anastomosis device is simple in structure, reasonable in design and convenient to use, the size of a blood vessel clamping space is adjusted by rotating the conical outer ring and the sleeve outer ring, so that blood vessels are fixed, blood vessel anastomosis is rapidly achieved, meanwhile, the traditional outward turning type end face combination mode is avoided, the contact area between the blood vessels is greatly increased, and blood leakage is prevented.

The embodiment of the invention provides an artery positioning detection method and device, electronic equipment and a storage medium, and the method comprises the steps: iteratively executing at least one round of the following steps in a process of continuously moving an image collection device at a target part until the integrity degree meets a preset condition: obtaining an image sequence collected by the image collection device in the round, stacking the image sequence into a stacked image, inputting the stacked image into a positioning network, and obtaining an image state output by the positioning network; and taking the last frame of image in the image sequence obtained when the integrity degree meets a preset condition as a target image, detecting the artery blood vessel in the target image, and determining a detection result indicating the health risk of the artery blood vessel. And identifying the image to assist the user in positioning the artery blood vessel, and detecting the artery blood vessel when the integrity degree meets a preset condition.

The invention relates to the technical field of model reconstruction, in particular to a method for reconstructing a coronary artery model based on coronary artery angiography. The method comprises the following steps: acquiring a coronary artery scanning image of a patient; performing three-dimensional coronary artery space structure construction on the coronary artery image of the patient to generate a three-dimensional coronary artery space model; performing blood vessel diameter analysis on the three-dimensional coronary artery space model to generate coronary artery blood vessel diameter data; acquiring an X-ray angiography image of a patient; performing coronary artery vein structure construction on the X-ray angiography image of the patient to generate a three-dimensional coronary artery vein model; and performing blood vessel wall thickness analysis on the three-dimensional coronary artery vein model to generate coronary artery blood vessel wall thickness data. According to the method, multi-modal modeling is carried out by combining the coronary artery scanning image and the X-ray angiography image of the patient, anomaly analysis is carried out on the coronary artery, and the accuracy and reliability of coronary artery model reconstruction are improved.

The invention discloses application of decitabine in preparation of a medicine for resisting vascular calcification, and belongs to the technical field of medical biology. A CKD mouse vascular calcification model is constructed through combination of 5 / 6 nephrectomy and high phosphorus diet (5 / 6NX), and it is observed that the expression level of DNMT3A in model mouse calcified blood vessels is remarkably increased, and the DNA methylation degree is remarkably increased. Based on this, people try to use decitabine to reduce the expression of DNMT, and discover that intraperitoneal injection of decitabine inhibits the expression of DNMT3A in CKD artery blood vessels and osteogenesis-like transdifferentiation of vascular smooth muscle cells, so that CKD-related vascular calcification is effectively relieved.

The invention discloses a vasculopathy risk identification system based on a machine learning model. A control host acquires a blood oxygen value, a pH value, a lactic acid value and a pressure value in blood vessel blood of an evaluator and a blood vessel inner wall structure image; the blood vessel is a vein blood vessel, analyzing the tube diameter and the thickness of the intima, the medium and the adventitia based on the structure image, inputting the blood oxygen value, the pH value, the lactic acid value, the pressure value, the tube diameter and the thickness of the intima, the medium and the adventitia of the assessor into a target vein blood vessel machine learning model, and training and outputting a vein blood vessel lesion risk identification result; the blood vessel is an artery blood vessel, and the composition and form of the artery blood vessel are identified and the stenosis degree value of the vessel diameter is calculated when the vessel diameter, the thickness of the inner, middle and outer membranes and artery plaques exist in the artery blood vessel are analyzed based on the structure image; and inputting the blood oxygen value, the pH value, the lactic acid value, the pressure value, the tube diameter, the thickness of the intima, the middle and the adventitia of the blood vessel, the composition and the form of the artery plaque and the tube diameter stenosis degree value of the assessor into a target artery blood vessel machine learning model to train and output an artery blood vessel lesion risk identification result.

The invention provides an implantable wireless passive blood pressure monitoring device, which relates to the technical field of blood pressure detection and comprises a blood pressure sensor and an in-vitro reading device, the blood pressure sensor comprises an outer inductance coil and an internal interdigital capacitor; the inductance coil is connected with the interdigital capacitor through a cross-layer line to form a capacitance-inductance LC loop; the inductance coil and the interdigital capacitor are packaged in the soft base material silicon rubber; the blood pressure sensor is used for being attached to the outer wall of an artery blood vessel, and the resonant frequency of the blood pressure sensor can change along with compression tensile deformation of the blood vessel; the in-vitro reading device is used for reading the resonant frequency of the blood pressure sensor; wherein the resonant frequency read by the in-vitro reading device is used for calculating a blood pressure value. The implantable wireless passive blood pressure monitoring device provided by the invention is used for providing a blood pressure monitoring mode with high measurement precision and small trauma so as to improve the accuracy and comfort of blood pressure monitoring.

The invention discloses a traditional Chinese medicine composition with an effect of improving artery blood vessel plaque and a preparation method and application thereof, and belongs to the technical field of traditional Chinese medicine. The technical problem to be solved is to provide a traditional Chinese medicine composition capable of improving vascular plaques such as carotid artery, aortic arch, brachial trunk, subclavian artery and the like aiming at the current situation that adverse reactions exist when statin lipid-lowering drugs and antiplatelet drugs are taken for a long time to treat artery vascular plaques. According to the technical scheme, the traditional Chinese medicine composition with the effect of improving the artery blood vessel plaque is characterized by comprising radix puerariae, red yeast rice, folium cortex eucommiae, hippophae rhamnoides leaves and natto.

The invention provides a carotid artery flow reduction thrombus protection device, and relates to the technical field of interventional medical instruments. The fixing assembly comprises a guide wire rod body, the guide wire rod body penetrates through the flow blocking part, and the flow blocking part is fixed to the guide wire rod body. The flow blocking part comprises a first opening located at the near end and a second opening located at the far end, the cross-sectional area of the second opening in the radial direction of the blood vessel is smaller than 30% of the cross-sectional area of the first opening in the radial direction of the blood vessel, and the flow blocking part reduces the blood flow in the carotid artery blood vessel when blood flows from the first opening to the second opening. The flow blocking part is arranged and provided with the first opening and the second opening, and the sectional area of the second opening in the radial direction of the blood vessel is smaller than half of the sectional area of the first opening in the radial direction of the blood vessel, so that the flow of blood is limited, and the pressure in the blood vessel is reduced; the problem that capillary injury is easily caused when blood flow directly recovers to the third level (mTICI level) is solved.

Systems and methods are provided for reducing the reliance on operator skill during vascular ultrasound procedures. The placement of an ultrasound probe to assess perfusion associated with a wound may be facilitated by receiving input suitable for identifying an anatomical region associated with the wound and providing an indication of a suitable initial probe position, and optionally, probe orientation, for acoustically interrogating a target arterial vessel known to provide perfusion to the anatomical region associated with the wound. Regions exhibiting arterial flow may be detected as the probe is moved, enabling arterial vessel detection and localization. A subregion within the detected arterial vessel and a beam steering angle may be autonomously determined for spectral Doppler data collection, enabling the measurement of hemodynamic measures associated with the arterial vessel. Example apparatus for securing the probe to the patient and facilitating probe positioning to search for a target vessel are disclosed.

The construction method comprises the following steps: performing decellularization treatment on a pig heart aorta blood vessel, compounding the treated pig heart aorta blood vessel with polyvinyl alcohol and methacryloylated gelatin to prepare a pre-gel solution, printing a designed model into a hollow tubular mold by using white resin through 3D printing, and preparing the hollow tubular mold into the artificial blood vessel stent with the anticoagulation performance. Injecting the pre-gel solution into a mold for cross-linking to obtain an artificial blood vessel stent with controllable shape and size, and finally loading an anticoagulant drug heparin on the prepared stent to obtain the heparin-loaded artificial blood vessel stent. Materials for preparing the pre-gel solution are selected, and advantage complementation of material functions can be achieved. The acellular matrix is beneficial to adhesion, proliferation and differentiation of cells; the composite polyvinyl alcohol and methacrylated gelatin improve the mechanical properties of the scaffold and improve the cell adhesion. Heparin is loaded on the artificial blood vessel stent to improve the anticoagulation performance of the stent and prevent thrombus. As an excellent biomedical material, the stent has a wide application prospect in the related fields of cardiovascular tissue engineering and biology.

The embodiment of the invention discloses an aneurysm rupture risk prediction device, a model training device and a storage medium. The prediction device comprises a first three-dimensional model construction module used for constructing a three-dimensional fluid model and a three-dimensional solid model based on target artery three-dimensional imaging data; the first fluid-solid coupling simulation model building module is used for building a computational fluid dynamics simulation module based on a three-dimensional fluid model, building a static solid analysis simulation module based on a three-dimensional solid model and then building a one-way fluid-solid coupling simulation model; the first index parameter acquisition module is used for taking the blood flow velocity distribution in the target arterial blood vessel in space and time as the input of the fluid-solid coupling simulation model to obtain a hemodynamic index parameter and a solid mechanics index parameter; and the risk prediction module is used for predicting the rupture risk of the aneurysm based on the hemodynamic index parameters and the solid mechanics index parameters. According to the technical scheme, the prediction accuracy of the aneurysm rupture risk can be improved.

The invention belongs to the technical field of medicines, and discloses an application of a small molecule compound in preparation of a product for preventing and / or treating pulmonary arterial hypertension and complications thereof. The small molecule compound is 8-[[4-(cyclopropanecarbonyl) piperazine-1-yl] methyl]-1, 3-dimethyl-7-(3-methylbutyl) purine-2, 6-diketone, and the structural formula is as shown in a formula (I): # imgabs0. The small molecule compound and pharmaceutically acceptable salts thereof have a remarkable treatment effect on pulmonary arterial hypertension and complications thereof, and can be used for treating pulmonary arterial hypertension and complications thereof. The effects of preventing and / or treating the pulmonary arterial hypertension include the reduction of right heart hypertrophy, the reduction of right ventricular systolic pressure, right heart enlargement, right heart dysfunction, pulmonary vascular remodeling, pulmonary arterial intima thickness, increase of vascular myelization, pulmonary arterial smooth muscle cell proliferation and migration, the reduction of the right ventricular hypertrophy, the reduction of the right ventricular hypertrophy, the reduction of the right ventricular hypertrophy and the reduction of the right ventricular hypertrophy. The pulmonary arterial intima thickness and the vascular myelization level are improved, pulmonary vascular remodeling is reversed, and pulmonary artery smooth muscle cell proliferation and migration are inhibited.

The present invention discloses a nursing pressing hemostasis device: comprising a core pressing mechanism, the core pressing mechanism comprising an upper annular frame; side connecting ears are symmetrically provided on both sides of the upper annular frame; and also comprising an adjustable strap, the two ends of the adjustable strap being fixed on the side connecting ears; precise positioning and pressure application: the ingenious design of the upper annular frame, the sliding track and the core functional shell in the core pressing mechanism ensures that the annular outer elastic pressing pad and the inner elastic pressing pad can be precisely aligned with the patient's arterial blood vessels. The stable sliding of the guide block in the long guide groove not only provides precise guidance for the movement of the core functional shell, but also enables the pressing pad to flexibly adjust its position according to actual needs, thereby ensuring precise pressure on the arterial blood vessels, greatly improving the success rate and effect of hemostasis, and effectively reducing hemostasis failure or delay caused by inaccurate pressing position.

The utility model discloses a wearable vascular elasticity detection and evaluation device, the wearable vascular elasticity detection and evaluation device comprises a host, a wearable wrist strap, a detection module and a control module, the detection module is arranged on the wearable wrist strap, and the position of the detection module corresponds to the radial artery of the wrist of a human body and the position nearby the radial artery; the control module is arranged in the host, the control module is in communication connection with the detection module, and the control module is used for controlling the detection module to obtain the pulse wave signal according to a preset instruction so as to generate a pulse wave waveform. According to the wearable vascular elasticity detection and evaluation device, radial artery pulse wave information is directly measured, optical pulse waves, measured by PPG, of arteries or blood capillaries or muscular tissue are more accurate, support is provided for more accurate evaluation of artery and blood vessel elasticity, meanwhile, detection is actively initiated by the wearable vascular elasticity detection and evaluation device, and the detection accuracy is improved. The user compliance and the equipment use efficiency are improved, and the health state of the user can be better detected and evaluated.

The invention discloses a preparation method of vascular tissue-derived extracellular vesicles, and belongs to the field of cytobiology. According to the preparation method of the extracellular vesicles, the artery blood vessel tissue is directly subjected to enzymolysis through collagenase, the extracellular vesicles are obtained by combining low-speed centrifugation and ultra-speed centrifugation methods and utilizing a differential centrifugation mode, and the technical blank of obtaining the extracellular vesicles from the blood vessel tissue is filled. Experimental results show that the extracellular vesicles can be successfully prepared from collagenase I, collagenase II, collagenase IV, collagenase V or collagenase IV combined with elastin, the prepared extracellular vesicles are different in particle size, form, yield, protein quantity, purity and the like, and the quality of the extracellular vesicles obtained by enzymolysis of collagenase IV combined with elastin is optimal. The extracellular vesicles are extracted from vascular tissues with normal physiological characteristics for the first time, a new source is provided for preparation of the extracellular vesicles, and the extracellular vesicles have great significance in expanding application of the extracellular vesicles.

The invention discloses an extravascular stent, and relates to the technical field of medical instruments. The extravascular stent comprises a first sleeve joint piece, a second sleeve joint piece and a third sleeve joint piece, the first sleeving piece is suitable for being arranged on the periphery of a vein in a sleeving mode, a plurality of deformation grooves are formed in the first sleeving piece, the area between every two adjacent deformation grooves is hollowed out, and the deformation grooves are used for enabling the first sleeving piece to adapt to the diameter change of the vein; the second sleeving piece is connected with one side of the second end of the first sleeving piece, and the second sleeving piece is suitable for being connected to the periphery of the artery blood vessel on the upstream side in a sleeving mode; the third sleeving piece is connected with the other side of the second end of the first sleeving piece, and the third sleeving piece is suitable for being connected to the periphery of the artery blood vessel on the downstream side in a sleeving mode. According to the extravascular stent provided by the invention, the structural design is improved, the mounting convenience of the extravascular stent is improved, the operation time is shortened, the adaptability of the extravascular stent to the diameter change of a vein is improved, the material cost is saved, and the treatment cost is reduced.

The invention relates to the technical field of biomedical materials, in particular to a solid-liquid two-phase embolism agent with a surface cilium structure and a preparation method thereof. Comprising an oil-phase liquid embolism material and a Janus cilia microsphere with a hydrophilic cilia structure, the oil-phase liquid embolism material is wrapped by the Janus cilia microspheres, and during wrapping, hydrophilic cilia structures in the Janus cilia microspheres are outwards exposed in a water phase, so that the surface of the solid-liquid dual-phase embolism agent has cilia structures; the cilia structure can improve the interaction force between embolism material particles and between the embolism material particles and a blood vessel wall, has excellent viscoelasticity and deformability, can reach finer artery blood vessels, realizes efficient thick and thin artery embolism, and improves the tumor embolism chemotherapy efficiency; the cilia structure is combined with a solid-liquid two-phase system, so that the embolism effect is improved, the stability of the embolism agent is enhanced, the action time is prolonged, the biocompatibility is optimized, and the application prospect is wide.

The invention relates to the technical field of biological 3D printing, in particular to a spray head device, a biological 3D printer and a using method of the biological 3D printer, and the spray head device comprises a moving seat, a suspension frame, an artery blood vessel printing assembly, a vein blood vessel printing assembly and a tissue printing assembly; the movable seat can move along an X axis, a Y axis and a Z axis; the suspension is installed on the movable base and can move along with the movable base. The artery blood vessel printing assembly is installed on the suspension frame and can conduct spraying to form artery blood vessels. The vein blood vessel printing assembly is mounted on the suspension frame and can spray to form vein blood vessels; the tissue printing assembly is installed on the suspension frame and can spray to form human tissue. Complex biological structural bodies such as artificial blood vessels or kidneys can be smoothly printed, the printed artificial blood vessels are rich in structure, different parts forming the artificial blood vessels or kidneys can be printed at the same time, the printing efficiency and the resolution ratio are improved, and the printing cost is reduced. And the performance of the printed complex biological structures such as artificial blood vessels or kidneys is guaranteed.

The present invention discloses the application of burdock root polysaccharide in the preparation of a medicament for treating pulmonary hypertension, belonging to the field of pharmaceutical technology. The present invention prepares a medicament for treating pulmonary hypertension with burdock root polysaccharide as the sole active ingredient. The medicament comprises an effective amount of burdock root polysaccharide and pharmaceutically acceptable excipients. Experimental results show that burdock root polysaccharide significantly reduces the increase in pulmonary artery pressure induced by monocrotaline in rats, significantly inhibits the increase in right ventricular hypertrophy index, significantly alleviates pulmonary artery endothelial injury, medial thickening, excessive proliferation of medial cells and infiltration of inflammatory cells in rats with pulmonary hypertension, significantly alleviates the degree of pulmonary artery vascular muscleization in rats with pulmonary hypertension, has the effects of reducing pulmonary artery vascular remodeling and lowering pulmonary artery pressure, and has a significant therapeutic effect on pulmonary hypertension and right ventricular hypertrophy in rats, and can be applied to the preparation of a medicament for treating pulmonary hypertension.

The invention belongs to the technical field of medicines, and discloses application of WZ3146 in preparation of products for preventing and / or treating pulmonary arterial hypertension and complications thereof. The WZ3146 and the pharmaceutically acceptable salt thereof have a remarkable treatment effect on pulmonary arterial hypertension and complications thereof, such as mean pulmonary arterial pressure, high right ventricular systolic pressure, right heart enlargement, right heart dysfunction, pulmonary vascular remodeling, pulmonary arterial intima thickness, increase of vascular myelization, pulmonary artery smooth muscle cell proliferation and migration and the like; the effects of preventing and / or treating pulmonary arterial hypertension comprise expanding the right heart, improving the pulmonary arterial intima thickness and the vascular myelization level, reversing pulmonary vascular remodeling and inhibiting pulmonary artery smooth muscle cell proliferation and migration.

A personalized whole-brain small artery angiogenesis method based on multiple constraints, belonging to the field of mathematical modeling algorithm development, includes the following steps: constructing a personalized three-dimensional model based on real head and carotid CTA images to determine the starting position of blood vessel growth; recording the geometric parameters (such as outlet area, outlet blood vessel length, etc.) of each blood vessel model based on the personalized model; using the Brainstorm standard head model three-dimensional point cloud file, uniformly sampling it as the ending position of blood vessel growth; based on multiple constraints, using the simulated annealing algorithm to optimize the geometric parameters of small blood vessels and calculate the spatial positions of bifurcations of blood vessels at all levels after meeting the constraints. The personalized whole-brain small artery angiogenesis real model of the present invention improves the accuracy for numerical simulation and hemodynamic calculation.

The utility model relates to a large area contact type thread type degradable magnesium alloy aortic blood vessel anastomat, including the conical inner ring, conical outer ring and sleeve outer ring that set gradually from inside to outside, be provided with blood vessel clamping space between the conical inner ring and conical outer ring, it is the thread cooperation between conical outer ring and sleeve outer ring, adjust the size of blood vessel clamping space through the rotation sleeve outer ring, sleeve outer ring. The utility model simple structure, reasonable in design, convenient to use, adjust the size of blood vessel clamping space through the rotation conical outer ring and sleeve outer ring to fixed blood vessel, realize blood vessel anastomosis fast, avoid the mode of the traditional everted type through end face combination simultaneously, greatly increase the contact area between blood vessel and prevent the occurrence of blood leakage.

To provide an endothelium function examination device of an arterial blood vessel which allows even an operator who is unskilled in determining a muscle tissue in a short axis image, to easily position the muscle tissue between the arterial blood vessel and an ultrasonic probe.SOLUTION: A muscle tissue region image generation part 94 generates a muscle tissue region image GKN which indicates a muscle tissue KN in an actual short axis image from image information which is present in the actual short axis image, using a learned model LM obtained by learning in advance the muscle tissue region image GKN which is present in the short axis image and stored, and a display control part 92 displays the muscle tissue region image GKN in a state of being overlapped with short axis images of a first short axis image display region G1 and a second short axis image display region G2 by the display control part 92. Thereby, it is possible to easily set an arrangement of an ultrasonic probe 24 on an upper arm 16 and a twisted position of the upper arm 16 so that the muscle tissue KN is positioned between an arterial blood vessel 20 and the ultrasonic probe 24.SELECTED DRAWING: Figure 1

The utility model provides a microsurgery vascular anastomosis training operation table, which is characterized in that a fixing block protruding upwards is fixedly arranged at the left position of the top surface of a base plate, and a left plain end needle head is fixedly inserted into the fixing block from left to right; a sliding block capable of adjusting left-right transverse sliding is arranged at the position, close to the right, of the top face of the base plate, and a right plain end needle is fixedly inserted into the sliding block from right to left. The left plain-end needle and the right plain-end needle are oppositely arranged above the top face of the base plate in a left-right spaced mode, and the two ends of the simulated blood vessel are fixedly connected to needle tubes of the left plain-end needle and the right plain-end needle in a sleeved mode respectively. According to the vascular anastomosis training operation table, the simulated blood vessel can be effectively fixed, pulse water flow or constant water flow is connected to the connecting base of the right plain end needle head, and the simulated blood vessel can be used for simulating an artery blood vessel or a vein blood vessel of a living animal for vascular anastomosis training. When the blood vessel anastomosis training operation table is used for training, blood vessels of living animals do not need to be used, implementation is convenient, and skill training is carried out.

The utility model discloses an instrument for negative pressure extraction and filtration of thrombus of an artery. Comprising a sheathing canal, a blocking balloon, a blood collection bag, a pipeline and a negative pressure providing structure, the blocking balloon is arranged on the outer side of the thrombus treatment sheathing canal, then the blood collection bag is connected to the outer side of the sheathing canal through the pipeline, the sheathing canal is connected with the blood collection bag through the pipeline, and a thrombus filter screen is arranged in the pipeline; a negative pressure providing structure is further arranged, the negative pressure providing structure is a structure with a cavity which is arranged on the outer side of the blood collection bag and used for constructing negative pressure by extracting gas in the blood collection bag, power is provided through the negative pressure to lead blood in the arterial blood vessel out into the blood collection bag, and thrombus is blocked at the position of the filter screen after the blood passes through the thrombus filter screen. The filtered safe blood flows into the blood collecting bag, the blood in the blood collecting bag can be transfused back to the patient again in a transfusing mode, and the blood in the blood collecting bag can also provide a blood source for substances for extracting platelet rich plasma (PRP) therapy.

The application discloses a kind of peripheral blood vessel tension measurement method and device based on ultrasound, it is related to the technical field of hemodynamics monitoring.The application collects the ultrasound image and arterial spectrum data of peripheral artery, obtains the pressure gradient variation characteristic parameter of peripheral artery from the ultrasound image of peripheral artery;According to the arterial spectrum data of continuous multiple heart cycles in the time period set according to peripheral artery, the resistance characteristic parameter of the rise and fall of blood flow velocity and the forward blood flow of peripheral artery are obtained;The pressure gradient variation characteristic parameter, resistance characteristic parameter and forward blood flow are used, which comprehensively reflect the peripheral arterial vessel tension situation.The application can use ultrasound to realize non-invasive, convenient and dynamic real-time reflection of peripheral vessel tension, and the hemodynamic changes can be fed back through the peripheral vessel tension waveform diagram, which is beneficial to early warning and helpful for health management and clinical guidance.

The application discloses an arteriovenous fistula blood vessel lining support and a use method thereof, and the arteriovenous fistula blood vessel lining support has a three-way pipe structure; the axes of two passages in the three-way pipe structure are on a straight line to form a straight pipe, and the axis of the other passage has a variable included angle with the straight line formed by the axes of the first two passages to form a bifurcated pipe; the straight pipe and the bifurcated pipe jointly form a three-way shape of the support with an inner cavity and have optional additional structures near each port; the straight pipe is used for being implanted into an arterial blood vessel; and the bifurcated pipe is used for sleeving a venous blood vessel which needs to be connected. After the arteriovenous fistula blood vessel lining support is embedded, the occurrence of turbulent flow is effectively reduced, blood composition deposition is reduced, the probability of vascular hyperplasia and vascular stenosis is reduced, the arteriovenous fistula maturation time is shortened, and the use time of the fistula is prolonged.

The invention relates to the field of animal models, in particular to a construction method and application of an experimental animal plaque model.The construction method includes the steps that after blood flow is blocked through a balloon method, induction is conducted by directly infiltrating a calcium chloride solution into an endarterium, and finally an artery blood vessel calcified plaque model is formed; therefore, an experimental animal model with high efficiency, repeatability, minimally invasive property and pathological correlation is provided for the research of the artery blood vessel calcified plaque.