50 results about "Vessel occlusion" patented technology

A hinged forceps for use during surgical procedures. A hinged surgical forceps for temporarily holding, clamping, and positioning patient tissue, such as a vascular forceps for occluding blood vessels. The hinged surgical forceps facilitate adjustment of the shape of the jaws, for example, to improve vascular occlusion during surgery. A method of temporarily occluding a blood vessel includes providing a hinged forceps as described herein, configuring the shape of the jaws of the forceps, and positioning the forceps to occlude the blood vessel.

The invention discloses a method for training a detection model for cerebrovascular occlusion detection and a related product. The method comprises the following steps: performing deboning operation based on CT perfusion imaging data to obtain target image data containing brain tissues and blood vessels; performing vascular occlusion region labeling on the target image data to obtain a three-dimensional occlusion region label; extracting a blood flow arrival time graph based on the CT perfusion imaging data; based on the target image data and the blood flow arrival time graph, extracting a blood vessel region feature volume after weighted fusion under blood flow arrival time gating; inputting the blood vessel region characteristic volume into the detection model to carry out cerebrovascular occlusion detection; and calculating a loss function based on the three-dimensional occlusion region label so as to train the detection model for cerebrovascular occlusion detection. By using the scheme of the invention, the accuracy, robustness and clinical applicability of occlusion detection can be improved.

A vascular occlusion catheter is configured for insertion, and at least partial inflation, into a targel blood vessel. The vascular occlusion catheter includes a proximal catheter shaft, a distal catheter shaft, and a semi-compliant or non-compliant occlusion balloon mounted at a proximal side thereof to the proximal catheter shaft and mounted at a distal side thereof to the distal catheter shaft. A central catheter shaft extends through the proximal catheter shaft, the occlusion balloon and into the distal catheter shaft. The central catheter shaft is constructed as the primary load-bearing chassis of the vascular occlusion catheter. The occlusion balloon defines a blown diameter between approximately twenty-five and approximately thirty-five millimeters and the occlusion balloon defines a double-wall thickness of between approximately 0.0003″ and approximately 0.0020″.

Disclosed is a non-invasive system and related methods to deliver electrical current to ischemic brain tissue rapidly with minimal set up, to treat acute ischemic stroke via direct cytoprotection and by collateral blood flow enhancement promoting recanalization of occluded vessel. In one embodiment, the system includes a cap with plurality of electrodes which are operable in combination to deliver an electrical current when in contact onto skin of the head region of the subject. In one embodiment, the electrical current delivery is individualized to target each individual's ischemic tissue only. In one embodiment, the electrode positioning can be selected from pre-determined electrode montages according to the location of the ischemia and vessel occlusion site. In one embodiment, the system can be applied as a standalone treatment or adjunct to reperfusion therapies to salvage the at-risk ischemic tissue (aka penumbra) and improve patient outcomes.

Described are methods and systems for transcervical access of the cerebral arterial vasculature and treatment of cerebral occlusions, including ischemic stroke. The methods and devices may include methods and devices which may provide aspiration and passive flow reversal, those which protect the cerebral penumbra during the procedure to minimize injury to brain, as well as distal catheters and devices to remove an occlusion. The methods and devices that provide passive flow reversal may also offer to the user a degree of flow control. Devices and methods which provide a way to securely close the access site in the carotid artery to avoid the potentially devastating consequences of a transcervical hematoma are also described.

A cardiac catheterization image recognition and evaluation method is disclosed. The first deep learning algorithm is used to conduct an object recognition process on the cardiac catheterization image to obtain the vessel object image. The image processing process is conducted to the cardiac catheterization image to obtain the vessel location image. The vessel object image and the vessel location image are combined to obtain the vessel contour image. The vessel type judging process is conducted to the vessel contour image to determine the type of vessel in the cardiac catheterization image. The second deep learning algorithm is used on the vessel contour image to detect the vessel occlusion location and to judge the vessel occlusion rate. Based on the type of vessel and the vessel occlusion rate at the vessel occlusion location, the cardiac catheterization image is evaluated to obtain the SYNTAX Score.

The invention discloses a bifurcated aneurysm stent structure. The structure comprises a far-end anchoring stent; a proximal anchoring stent; the skeleton is arranged to be of a bent structure, the two ends of the skeleton are connected with the far-end anchoring stent and the near-end anchoring stent respectively, and the far-end anchoring stent and the near-end anchoring stent can be matched to limit the skeleton to a to-be-treated position in a blood vessel; the covering film is connected to the skeleton and covers the skeleton in the bending direction of the skeleton, and the skeleton and the covering film are matched to support the position to be treated in the blood vessel. According to the invention, a tumor neck opening can be effectively blocked, the blood flow of a blood vessel can be kept smooth, the thrombosis probability is reduced, the problem of vascular occlusion is avoided, and the occurrence of ischemic events is reduced.

Systems and methods are described for determining a fluid congestion status of a subject, the method being carried out by at least one processor executing operations comprising: receiving an initial right atrial pressure for the subject; causing, over a time period, a vessel occlusion device to perform an occlusion cycle to change blood flow resistance in a blood vessel of the subject; receiving monitored readings for a right atrial pressure response to the changed blood flow resistance in the blood vessel over the time period; and determining, for the subject and based on the readings representing the right atrial pressure response, a fluid congestion status associated with a heart of the subject.

The invention relates to the technical field of interventional medical instruments, and discloses a handheld ultrasonic system for treating vascular occlusion and a using method.The handheld ultrasonic system for treating vascular occlusion comprises a guide wire used for moving to an internal occlusion part of a blood vessel along the blood vessel, and further comprises a positioning guide wire and a catheter, the positioning guide wire is used for entering the main branch from the side branch to perform reverse puncture on the artery plaque, a positioning guide wire cavity is formed in the catheter, the positioning guide wire can move along the positioning guide wire cavity, a positioning guide wire outlet communicated with the positioning guide wire cavity is formed in the catheter, a balloon is arranged at the far end of the catheter, and the balloon can synchronously move with the catheter in a contraction state; the balloon is additionally arranged at the front end of the catheter, the balloon can be matched with the blood vessel wall or directly form a channel in the balloon in the expansion state, the channel restrains the guide wire to move along the channel, an inlet of the channel is communicated with the guide wire catheter, an outlet of the channel faces the artery plaque, and reverse puncture of the artery plaque is completed.

The present disclosure relates to medical devices including occlusion devices, clot retrieval systems, and stents. More particularly, the medical devices described herein measure characteristics for intravascular treatment sites. The medical devices may include pressure sensors and / or length sensors that may be used to determine the effectiveness of the medical devices during or after treatment. These sensors may be particularly helpful when used on an occlusion device or a clot removal device.

An intravascular lithotripsy (IVL) catheter for treating vessel occlusions comprises a catheter shaft with a longitudinal axis, a balloon capable of inflation and deflation with fluid, and one or more emitters within the balloon's interior. These emitters can emit acoustic waves when the balloon is inflated. The catheter also includes an inner member partially internal to the balloon and wires embedded in the inner member, which are coupled to the emitters and configured to transmit signals to them.

Systems and apparatuses are included that are configured to determine an effectiveness of apparatus and methods used to diagnose and unblock microvascular obstruction (MVO). An infusion system blocks antegrade flow for a short time and measures vascular pressure response as an infusate is infused in stepwise fashion at increasingly higher flow rates. During the antegrade flow occlusion, calculations of a real-time vascular resistance can be obtained using a formula R(t)=(t) / Qmean(t) where: Qmean (t) is flow mean values generated by the infusion system; P(t) is a distal pressure response in a vessel generated from the infusion of the infusate; and R(t) is the calculated real-time vascular resistance using the two other known parameters.

A portable device for detecting a large vessel occlusion in a patient's brain by transmitting a signal into both sides of the brain and receiving the reflections of the transmitted signals to capture a single reflection data point of the characteristics of the blood vessels and brain tissue on both sides of the brain. Using the captured single reflection data point values to perform a comparative analysis between the right and left side of the brain, and based on this analysis, assessing whether the patient is experiencing a large vessel occlusion. If so, the device generates an alert.

Described are methods and systems for transcervical access of the cerebral arterial vasculature and treatment of cerebral occlusions, including ischemic stroke. The methods and devices may include methods and devices which may provide aspiration and passive flow reversal, those which protect the cerebral penumbra during the procedure to minimize injury to brain, as well as distal catheters and devices to remove an occlusion. The methods and devices that provide passive flow reversal may also offer to the user a degree of flow control. Devices and methods which provide a way to securely close the access site in the carotid artery to avoid the potentially devastating consequences of a transcervical hematoma are also described.

The present disclosure relates to medical devices including occlusion devices, clot retrieval systems, and stents. More particularly, the medical devices described herein measure characteristics for intravascular treatment sites. The medical devices may include pressure sensors and / or length sensors that may be used to determine the effectiveness of the medical devices during or after treatment. These sensors may be particularly helpful when used on an occlusion device or a clot removal device.

The vascular plug includes an upper structure that can expand from a collapsed percutaneous insertion configuration to an expanded deployed or use configuration. The upper structure includes a primary and secondary three-dimensional shape that allows occlusion of a wide range of vessel sizes from small to large through a small, out of proportion, delivery catheter. The plug includes shape memory elements for creating the radial force and the larger secondary three-dimensional twist or helical shaped upper structure required to create the target vessel occlusion.

Embodiments of the present application provide a full occlusion recanalization device and method, relating to the field of medical devices, aiming to improve the problem of high difficulty of blood vessel occlusion opening operation. The full occlusion recanalization device comprises a catheter group, a cutting blade, a fixed balloon and an operating handle; the cutting blade and the fixed balloon are fixed at the distal end of the catheter group, and the operating handle is used to drive the catheter group to reciprocally move the cutting blade to repeatedly cut the blood vessel occlusion tissue; the operating handle is provided with a stamping port, the stamping port is communicated with the fixed balloon through the catheter group, and the expanded fixed balloon is supported and fixed in the blood vessel, so that the cutting blade can always be located between the inner walls of the blood vessel during cutting. The full occlusion recanalization method is implemented by using the above device, the position of the cutting blade is adjusted by the fixed balloon and the operating handle, and the blood vessel of the full occlusion blood vessel can be safely opened in a fast and simple manner without the need for active driving such as electricity or laser.

A vascular occlusion assembly includes a vascular occlusion device configured for implantation in an aneurysm sac, the vascular occlusion device having a delivery configuration when confined within a delivery catheter and having a deployed configuration when released from the delivery catheter into the aneurysm sac. The vascular occlusion assembly also includes a delivery wire having a distal end secured to the vascular occlusion device. The delivery wire has an electrolytically disconnectable junction adjacent the vascular occlusion device. At least a portion of the electrolytically disconnectable joint is composed of molybdenum (Mo) or a molybdenum alloy.

The invention discloses a magnetic guidance two-way docking system and method for vascular occlusion recanalization. The magnetic guidance two-way docking system for vascular occlusion recanalization comprises a first catheter, a second catheter, a third catheter, a micro-threading needle and a pushing assembly. A first magnetic piece is arranged at the end part of the first conduit; a second magnetic piece is arranged at the end part of the second conduit; the first magnetic piece and the second magnetic piece attract each other; the first conduit and the second conduit form an assembly channel for the third conduit to pass through; the pushing assembly is used for driving the micro-threading needle to reciprocate along the annular channel. The channels are established from the two sides of the target position respectively, the first guide pipe and the second guide pipe are arranged, and alignment is achieved through mutual attraction of the first magnetic part and the second magnetic part. And then, the micro-threading needle is fed from one catheter through the pushing assembly, so that the micro-threading needle accurately penetrates through the target position under the guidance of magnetic force and enters the catheter on the opposite side to form a guide wire passage, and the difficulty of traditional operation is effectively reduced.

The invention relates to a vascular occlusion system based on a shape memory polymer material, and the system comprises a plugging block which is made of shape memory polymer foam and has a loading state, an implantation state and a preset state, and the plugging block is internally provided with a threading channel; the interventional catheter is used for accommodating the plugging block in the loading state and is suitable for interventional delivery; the delivery shaft extends in the interventional catheter, the near end of the delivery shaft is an operation end, the far end of the delivery shaft is provided with a connecting section, the connecting section extends into the threading channel and is clamped by the plugging block in the loading state, and when the plugging block is released, the plugging block is released. The connecting section and the plugging block extend out of the interventional catheter and are pre-positioned at an implantation position, and after the plugging block expands to an implantation state and is positioned at the implantation position, the connecting section is moved out. By improving the structure of the plugging block and matching the plugging block with the delivery shaft, the operation safety can be improved, and the treatment effect can be guaranteed.

Tissue-mounted devices and methods for monitoring a thermal transport property (e.g., thermal conductivity, thermal diffusivity, heat capacity) of tissue, such as skin, are disclosed. The devices conformally mount to the tissue and comprise one or more thermal actuators and a plurality of sensors. The actuator applies heat to the tissue and the sensors detect a spatio temporal distribution of a physiological tissue parameter or physical property resulting from the heating. This spatio temporal information may be correlated with a rate, velocity and / or direction of blood flow, the presence of a vascular occlusion, circulation changes due to inflammation, hydration level and other physiological parameters.

Dilator hub for a delivery system for a vascular occlusion device. 1.1) Perspective view; 1.2) Perspective view; 1.3) Perspective view; 1.4) Perspective view; 1.5) Top view; 1.6) Bottom view; 1.7) Left side view; 1.8) Right side view; 1.9) Front view; 1.10) Rear view

Multivalent anti-platelet glycoprotein I(b)alpha antibodies can cause severe side effects. The present disclosure provides humanized antibodies specifically recognizing glycoprotein I(b)alpha and lacking a Fc portion, therefore Bleeding Time do not interact with Fc receptor. The humanized antibodies are capable of preventing platelet activation and aggregation, and reducing thrombus size / growth and prevent vessel occlusion. They can be also very useful to decrease platelet-tumor cell interaction and decrease tumor metastasis. At therapeutic doses, the humanized antibodies lack the ability to induce platelet activation, induce thrombocytopenia; and / or prolong bleeding time.

This application discloses a method and device for predicting first-pass recanalization in preoperative ADAPT aspiration, relating to the field of data processing for AIS patients. The method includes: acquiring preoperative examination images of the patient to be evaluated, and performing vascular occlusion segment localization, SVS candidate region determination, and thrombus ROI generation to obtain the thrombus ROI, and then extracting the radiomics features of the thrombus ROI; inputting the radiomics features of the thrombus ROI into a pre-trained machine learning-based prediction model to predict the probability of first-pass recanalization. This application obtains the thrombus ROI of the occluded segment in the patient's blood vessel through vascular occlusion segment localization, SVS candidate region determination, and thrombus ROI generation, and then extracts radiomics features that characterize "aspiration difficulty / device response," thereby more accurately predicting the probability of first-pass recanalization in ADAPT aspiration.

The present disclosure features devices, systems, and kits for vascular occlusion and methods of use thereof.

The embodiment of the invention discloses a mechanical thrombectomy risk prediction system and method for elderly patients. The system comprises a database establishment module, a risk factor screening module, a model construction module and an embolectomy risk prediction module. According to the embodiment of the invention, for an advanced AIS-aLVO patient, on the basis of one-stop multi-mode CT information, by analyzing related collateral tract omics information, conventional image omics information and clinical data, risk factors influencing the advanced patient acute stage mechanical thrombus extraction poor prognosis are screened out, a Nomogram-based risk prediction model is constructed, and the risk prediction result of the advanced patient acute stage mechanical thrombus extraction poor prognosis is obtained. The generalization ability of the model and the clinical popularization feasibility are further verified through prospective queue research, and finally a set of mechanical thrombectomy risk assessment system for the elderly patients with acute precirculatory great vascular occlusion is established, so that more evidence-based basis is provided for preoperative decision making of clinicians; the individualized and precise diagnosis and treatment of the elderly ischemic stroke patient can be realized.

An occlusion assembly for occluding the aorta of a patient is presented. The occlusion assembly includes an elongate shaft of two separate extrusions to which an elastomeric balloon envelope is bonded to an end of each. A support wire extends through the elongates shaft and the balloon envelope. At the proximal end of the shaft the proximal end of the support wire is secured to a proximal hub to give the entire assembly sufficient stiffness to be advanced into the vasculature of the patient. The balloon envelope is pre-molded to have a reverse teardrop or “ice cream cone” like shape and will maintain that general shape throughout inflation to the fully inflated state. If the balloon envelope is over inflated, the balloon envelope will advance distally and proximally (lengthening) along the support wire without damage to the surrounding vessel.

The invention discloses a catheter rehemorrhagic disease and vascular occlusion interventional therapy device integrated with pressure sensing, and belongs to the technical field of vascular interventional therapy, and the catheter rehemorrhagic disease and vascular occlusion interventional therapy device integrated with pressure sensing comprises a pressure pump for controlling pressure, a pressure output port of the pressure pump is in through connection with a stamping pipe through a hose, the other port of the stamping pipe is in through connection with a catheter, a guide wire is in through connection in the catheter in the central axis direction, the end, away from the stamping pipe, of the catheter is sleeved with a balloon, and a liquid outlet is formed in the area, located in the balloon, of the catheter. Embedded circular grooves are symmetrically formed in the positions, located on the two sides of the balloon, of the outer portion of the catheter, and pressure sensors are installed in the embedded circular grooves in an embedded mode; the vascular treatment intervention device can drive the pressure sensor to move and be attached to the inner wall of a blood vessel when the balloon is controlled to expand to block the blood vessel, so that the pressure change is accurately measured, and the blocking treatment effect is improved.