95 results about "Blood vessel occlusion" patented technology

Ultrasound catheter devices and methods provide enhanced disruption of blood vessel obstructions. Generally, an ultrasound catheter includes an elongate flexible catheter body with one or more lumens. An ultrasound transmission member or wire extends longitudinally through the catheter body lumen and, in many embodiments, a guide wire tube also extends through the same lumen. A distal head is fixed to or otherwise mechanically coupled with the distal end of the ultrasound transmission member or wire and is positioned adjacent the distal end of the catheter body. Although the distal end of the catheter body overlaps the distal head, the distal head is not directly affixed to the distal end of the catheter body. Thus, the distal tip may move freely, relative to the distal end of the catheter body when ultrasonic energy is applied through the ultrasound transmission member. Such a freely floating distal head enhances the efficiency of an ultrasound catheter, enabling the catheter to ablate calcific occlusions and increasing the useful life of the ultrasound transmission member and catheter.

A system used in a blood vessel when an interventional procedure is being performed in a stenosed or occluded region, which is capable of capturing embolic material which may be released into a blood vessel during a therapeutic interventional procedure at the site of a lesion in the blood vessel. The system is adapted to be utilized in a collateral blood supply system adapted to enable the flow of blood to bypass the blood vessel upon blocking thereof and to enable the reverse flow of blood through the blood vessel upon unblocking thereof. The system includes a guide wire, including a distal end, adapted to be positioned in a blood vessel relative to an interventional procedure site. A guide catheter, including a distal end, is adapted to enable the interventional procedure to be performed, and to be inserted over the guide wire and through a patient's vasculature to a position in the blood vessel relative to the interventional procedure site. An occluding device for occluding and blocking a blood vessel at a location relative to the interventional procedure site is adapted to be positionable at a location relative to he interventional procedure site, to be expandable so as to prevent and block the flow of blood past the occlusion, and to enable the capture of embolic material which may be released into the blood in the blood vessel during the therapeutic interventional procedure, and to be contracted to unblock the blood vessel and enable the recovery of captured embolic material.

Catheter devices having low profile shafts and laterally deployable members (e.g., cannulas, needles, etc.) that may be extended or advanced laterally from the catheter shaft. Also disclosed are methods for bypassing a vascular obstruction (e.g., a chronic total occlusion or other full or partial obstruction) wherein a guidewire is entrapped in a subintimal space adjacent to the obstruction. A catheter of the foregoing character is advanced over the entrapped guidewire and into the subintimal space. The laterally deployable member is then advanced or extended from the subintimal space back into the true lumen of the blood vessel distal to the obstruction. A second guidewire is then advanced through or along the laterally deployable member. The catheter and first guidewire are then removed and one or more working device(s) (balloons, atherectomy devices, setnts, etc.) is/are advanced over the second guidewire and used to establish a subintimal bypass channel through which blood may flow around the obstruction.

Ultrasound catheter devices and methods provide enhanced disruption of blood vessel obstructions. Ultrasound catheter devices generally include an elongate flexible catheter body with one or more lumens, an ultrasound transmission member extending longitudinally through the catheter body lumen and a distal head coupled with the transmission member and positioned adjacent the distal end of the catheter body for disrupting occlusions. Improved features of ultrasound catheters include catheter bodies and ultrasound transmission members with increasing distal flexibility, guidewire tubes allowing contact between a guidewire and an ultrasound transmission member, distal heads with improved guidewire lumens, and torquable proximal housings for enhancing disruption of blood vessel occlusions.

A blood occlusion auger having an in vivo distal auger tool coupled in operative association with an ex vivo auger control for opening and traversing occlusions in a blood vessel The auger control allows the selection of predetermined threshold forces and step-lengths values and operates in successive repetition of identical sequential stages, to traverse occlusions. Once disposed adjacent an occlusion, the auger tool, commanded by the auger control, operates in two states, first to radially dilate the vessel and second to penetrate distally into a furrow.

Disclosed herein are systems and methods for protecting a subject from embolisms during TAVI and other percutaneous valve procedures. Some embodiments include two flexible catheters designed to pass over a guidewire into two separate arteries, such as carotid or innominate arteries, each flexible catheter including a vessel blocking mechanism and a bypass feature that prevents ischemia while the vessel blocking mechanism is in use. Other embodiments include a single, bifurcated flexible catheter having two arms, each of which is configured to protect a different artery. In some embodiments, each arm includes a vessel blocking mechanism and a bypass feature that prevents ischemia while the vessel blocking mechanism is in use. In some embodiments, the systems also may include one or more concentric guidewires.

An occlusion device delivery system and methods are provided in which an expandable coiled implant can be delivered using the delivery system. The system can comprise a catheter having a lumen extending between distal and proximal portions. The distal portion can have proximal and distal apertures extending through a wall of the catheter. The expandable coiled implant, which can be wound about the distal portion, can have a proximal section that extends within the proximal aperture and a distal section that can extend radially within the distal aperture. Further, the system can comprise an elongate member that extends through the lumen and engages and radially restrains the at least one of the proximal and distal sections within its respective aperture while engaged with the member.

Ultrasound catheter devices and methods provide enhanced disruption of blood vessel obstructions. Generally, ultrasound catheters include an elongate flexible catheter body with one or more lumens, an ultrasound transmission member extending longitudinally through the catheter body lumen and a distal head coupled with the transmission member and positioned adjacent the distal end of the catheter body for disrupting occlusions. Improved features of ultrasound catheters include prevention of independent rotation of the ultrasound transmission member, a safety anchor for the distal head, a one-piece transmission member/distal head and the like.

A method of ameliorating tissue damage resulting from hypoxia or ischemia by administering systemically a synthetic oxygen carrier to an individual having or suspected of having blood vessel obstruction is disclosed. A synthetic oxygen carrier in a physiologically acceptable vehicle, wherein the synthetic oxygen carrier comprises submicron sized particles capable of passing through emboli-obstructed blood vessels is also disclosed.

Occlusion bypassing apparatuses are disclosed for re-entering the true lumen of a vessel after subintimally bypassing an occlusion in a vessel. The occlusion bypassing apparatuses include a shaft component and a needle component slidably disposed within the shaft component and having an angled configuration when deployed. In embodiments hereof, the needle component has an angled distal tip segment that may be utilized to selectively bend a flexible distal portion of the shaft component in order to extend the flexible distal portion towards the true lumen of the vessel. The needle component is distally advanced relative to the shaft component to pierce through the intima of the vessel and thereafter enter the true lumen.

A method of removing vascular blockage includes providing a catheter system. comprising an outer catheter, a cutting catheter having a serrated distal end, a bypass catheter, and a guidewire. In the catheter system, the bypass catheter is slidably disposed within the cutting catheter and the outer catheter. The method includes positioning a distal end of the catheter system at a proximal end of an occlusion located within a vessel and moving the bypass catheter through the occlusion so that a medicated treatment solution may be delivered through the bypass catheter to an area of the brain or other tissue served by the vessel blocked by the occlusion. Both during and after the delivery of medicated treatment solution to the blocked part of the vessel with the bypass catheter, the physician may engage the occlusion with the cutting catheter by moving the cutting catheter in a clockwise/counterclockwise or forward/backward direction within the outer catheter, cutting and then removing at least a portion of the occlusion from the vessel.

A biodegradable blood vessel narrowing device, comprising: a biodegradable element; an anchoring element; wherein said anchoring element is anchored to a blood vessel wall and at least one external dimension of said biodegradable element is reduced upon biodegradation of said biodegradable element thereby pulling said blood vessel walls toward one another.

An apparatus, system, and method for re-canalization or opening a passage through an occlusion in a blood vessel is provided. The apparatus and method, which are appropriate for cardiovascular and peripheral vessels, use a pulling member and a spring element, for example a compression spring, to oscillate a distal component disposed at a distal end of the spring element. The apparatus further includes a sleeve covering the spring element and at least a portion of the distal component. The sleeve may reduce friction between the spring element and the vessel lumen as the spring element vibrates during operation of the apparatus. The sleeve may also serve to protect or seal the spring element from blood and/or plaque debris that is loosened from an occlusion during a re-canalization procedure.

Occlusion bypassing apparatuses are disclosed for re-entering the true lumen of a vessel after subintimally bypassing an occlusion in a vessel. The occlusion bypassing apparatuses include a shaft component and a needle component slidably disposed within the shaft component and having an angled configuration when deployed. In embodiments hereof, the needle component has an angled distal tip segment that may be utilized to selectively bend a flexible distal portion of the shaft component in order to extend the flexible distal portion towards the true lumen of the vessel. The needle component is distally advanced relative to the shaft component to pierce through the intima of the vessel and thereafter enter the true lumen.