137 results about "Coelom" patented technology

An intravascular stent assembly for implantation in a body vessel, such as a coronary artery, includes undulating circumferential rings having peaks on the proximal end and valleys on the distal end. Adjacent rings are coupled together by links. The rings and links are arranged so that the stent has good conformability as it traverses through, or is deployed in, a tortuous body lumen. The stent is also configured such that the likelihood of peaks and valleys on adjacent rings which point directly at each other to overlap in tortuous body vessels is reduced.

A scanning endoscope, amenable to both rigid and flexible forms, scans a beam of light across a field-of-view, collects light scattered from the scanned beam, detects the scattered light, and produces an image. The endoscope may comprise one or more bodies housing a controller, light sources, and detectors; and a separable tip housing the scanning mechanism. The light sources may include laser emitters that combine their outputs into a polychromatic beam. Light may be emitted in ultraviolet or infrared wavelengths to produce a hyperspectral image. The detectors may be housed distally or at a proximal location with gathered light being transmitted thereto via optical fibers. A plurality of scanning elements may be combined to produce a stereoscopic image or other imaging modalities. The endoscope may include a lubricant delivery system to ease passage through body cavities and reduce trauma to the patient. The imaging components are especially compact, being comprised in some embodiments of a MEMS scanner and optical fibers, lending themselves to interstitial placement between other tip features such as working channels, irrigation ports, etc.

The present invention relates to methods and articles for anchoring within a natural bodily lumen. An anchor is adapted to provide differing radially-outward forces along its length, a securing force and a transitional force. Production of these forces can be controlled by varying a physical property of the anchor, such as its stiffness, thickness, or shape. For example, the stiffness of an elongated anchor can be varied from a relatively soft value at its proximal and distal ends to a relatively stiff value at its center by varying the diameter of wire forming the anchor, thereby tailoring it to an intended application. Such force tailoring can be combined with external barbs and used to reliably anchor other instruments, such as feeding tubes and intestinal sleeves.

A biopsy device having an endoscope comprises a biopsy instrument, suitable for collecting at least one tissue sample from a body lumen, such as a mammary duct, and a cutter introducer sized for receiving the biopsy instrument and introducing the biopsy instrument into a mammary duct to retrieve a tissue sample therefrom.

A shaping device and a cardiac lead, both adapted to be disposed in a coronary sinus of a patient's heart, are provided. In one method, a patient is treated by deploying in the patient's coronary sinus a shaping device and a cardiac lead and using the shaping device to modify mitral valve geometry.

Systems and methods for delivering implantable devices, catheters, or substances in or near and / or restoring flow through body lumens, such as blood vessel lumens are described. A catheter having a proximal portion of a first diameter and a distal portion of a second diameter (smaller than the first diameter) is advanced into a body lumen. The distal portion of the catheter is caused to expand to a diameter that is larger than the second diameter but no larger than the first diameter. A working device is then advanced out of the distal end of the catheter and used to remove obstructive matter, deliver an implantable device or substance and / or restore flow. The distal portion can be reduced in diameter prior to removal from the body. A stand alone, guide catheter is also disclosed possessing high resistance to kinking even with a very thin wall.

The method disclosed may be used following a prostatectomy may comprise inserting an instrument having an end effector into the bladder lumen via the urethra; using the end effector to urge the bladder wall to the pelvic floor and drive an anchor through the bladder wall into the pelvic floor, thereby connecting a balloon harness within the bladder to the pelvic floor; withdrawing the end effector; inserting and inflating a balloon catheter within the balloon harness, thereby pressing the bladder wall surrounding the bladder opening against the pelvic floor; maintaining the balloon catheter in place and draining the bladder during the time required for the tissues to effectively knit; and then deflating and withdrawing the balloon catheter and disconnecting and withdrawing the balloon harness. The instrument may comprise one or more tubes that support an end effector comprising a positioner and an anchor driver.

The invention is directed to an expandable stent for implanting in a body lumen, such as a coronary artery, peripheral artery, or other body lumen. The invention provides for an intravascular stent having a plurality of cylindrical rings connected by undulating links. The stent has a high degree of flexibility in the longitudinal direction, yet has adequate vessel wall coverage and radial strength sufficient to hold open an artery or other body lumen. The stent can be compressed or crimped onto a catheter to a very low profile since the peaks that are adjacent the curved portion of the undulating link are shorter than other peaks in the same cylindrical ring to prevent overlap yet still achieve a very low profile, tightly crimped stent onto a catheter.

Systems and methods for crossing stenosis, partial occlusions, or complete occlusions within a body lumen. The systems generally include an elongate member such as a hollow guidewire that houses a rotatable and translatable drive shaft. The drive shaft typically has a distal portion that is advanced to create a path in the occlusive material that is large enough to allow the hollow guidewire to cross the occlusive material.

Systems and methods for crossing stenosis, partial occlusions, or complete occlusions within a body lumen. The systems generally include an elongate member such as a hollow guidewire that houses a rotatable and translatable drive shaft. The drive shaft typically has a distal portion that is advanced to create a path in the occlusive material that is large enough to allow the hollow guidewire to cross the occlusive material.

An expandable stent for implantation in a body lumen, such as an artery, is disclosed. The stent consists of a plurality of radially expandable cylindrical rings generally aligned on a common longitudinal stent axis and interconnected by one or more interconnecting links placed so that the stent is flexible in the longitudinal direction. The link pattern is optimized to reduce strain on the links and enhance longitudinal flexibility and security of the stent. The stent includes a distal end ring and a proximal end ring that have a length that is shorter than the length of the body rings.

A removable stent for implantation into a lumen in a human body. The stent is made from a soft, flexible fiber having an outer surface. An outer bioabsorbable / degradable coating is applied to the outer surface of the filament causing it to become rigid. The coating softens in vivo through absorption and / or degradation such that the stent is readily passed or removed from the lumen as a softened filament after a pre-determined period of time through normal flow of body fluids passing through the lumen or by manual removal.

An endoscopic device for locomotion in a body cavity according to a prefixed advancing direction (A) comprising at least a variable length intermediate section (1a, 21a) extending between a front end section (1b, 21b) and a rear end section (1c, 21c). First and second clamping means (7, 12, 27, 32) are integral to the front and rear section, for alternately grasping respective surrounding portions of wall (P) of the body cavity. Sucking means (13, 14, 37, 38) are associated to the first and second clamping means for creating a depression sufficient to cause the body cavity wall portions to collapse within the first and second clamping means while they are in an open condition. Means for actuating alternate extensions and retractions of the intermediate section and actuating means (6, 11, 26, 31) of the first and second clamping means are further provides for synchronous operation to generate a forward motion of the rear end section due to a retraction of the intermediate section, the wall portion (P) surrounding the first clamping means being firmly held therebetween, and to generate a forward motion of the front end section due to an extension of the intermediate section, the wall portion (P) surrounding the second clamping means being firmly held therebetween.

A three-dimensional model, wherein coelom models such as blood vessels are stackingly molded based on tomogram data on a subject, the peripheries of the coelom models are surrounded by a three-dimensional model forming material, the three-dimensional model forming material is hardened, and the coelom models are fused or molten and removed, whereby a specified three-dimensional model can be formed.

A device for occluding a body lumen, and particularly contraceptive or sterilization device for occluding a reproductive tract or lumen to prevent the passage of reproductive cells through the tract or lumen, generally comprising a tubular member, and a mesh member, transversely disposed on the tubular member lumen. The mesh member is permeable to allow for tissue ingrowth, which produces a tissue impregnated mesh occluding the body lumen. The occluding device of the invention can be used in the fallopian tubes of a female patient, the vas deferens of a male patient, or other body lumen.

A treatment procedure is disclosed which involves the short term, non-permanent occlusion of the patient's blood vessels by depositing a bioabsorbable embolic mass within the patient's blood vessel. The procedure is particularly suitable for treating uterine disorders by occluding a patient's uterine arteries. A therapeutically effective time period for occlusion of a uterine artery is from about 0.5 to about 48 hours, preferably about 1 to about 24 hours, with occlusion times of about 1 to about 8 hours being suitable in many instances. The embolic mass may bioabsorbable particulate with minimum transverse dimensions of about 100 to about 2000 micrometers, preferably about 300 to about 1000 micrometers. The particulate may be a polymeric material formed of polylactic acid, polyglycolic acid or copolymers thereof, or a swellable copolymer of lactic acid and polyethylene glycol. The embolic material may be delivered to an intracorporeal site as a biocompatible solution containing a solute which is relatively insoluble in a water based fluid and a solvent which is relatively soluble in the water based fluid, where the solute forms the embolic mass which occludes or partially occludes a body lumen or fills or partially fills a body cavity.

A stent for treating a region of a body lumen wherein at least two vessels form a junction includes a compressed state and an expanded state. In the expanded state, the stent is generally an ellipsoidal, spheroidal, or spherical shape. The stent is delivered to the junction in the compressed state disposed within a sleeve. Once at the junction, the sleeve is withdrawn proximally relative to the stent such that the stent is released from the sleeve and expands to the expanded state. A balloon may further expand the stent to appose the walls of the body lumen at the junction.

An apparatus for use in insufflation of a body cavity 5, such as through a trocar 6 is described. One such application is laparoscopic surgery. The device is also suitable for use in any situation involving insufflation of a body cavity such as in arthroscopies, pleural cavity insufflation (for example during thoracoscopy), retroperitoneal insufflations (for example retroperitoneoscopy), during hernia repair, during mediastinoscopy and any other such procedure involving insufflation. The apparatus comprises a reservoir 1 for storing an liquid solution, an aerosol generator 2 for aerosolising the solution, and a controller 3 for controlling operation of the aerosol generator 2. Aerosolised liquid solution (which main contain a pharmaceutical) is entrained with insufflation gas using a T-piece connector or housing 30 having an insufflation gas inlet 31 and an outlet 32. The connector 30 also comprises an aerosol supply conduit 34 for delivering the aerosol from the aerosol generator 2 into a mixing chamber 33 in which the aerosol is entrained with insufflation gas. The aerosol insufflation gas mixture passes out of the connector 30 through the outlet 32 and is delivered along the insufflation gas conduit 15 to the trocar 6 for delivery into a body cavity 5. The connector 30 causes a substantial sudden reduction in the velocity of the insufflation gas from the insufflation gas inlet as it enters the mixing chamber 33. The connector 30 also causes a gradual increase in the velocity of the insufflation gas with entrained aerosol between the mixing chamber 33 and the outlet 32.

The invention discloses a method for blocking up obstacle in coelom and a blocking device thereof. The blocking device comprises a guide wire, a guide tube and a blocking substance; one end of the guide wire penetrates the guide tube and cavity of the blocking substance; a remote end of the blocking substance is fixed to the guide wire, so as to pull a near end of the guide wire, thereby axially compressing the spread blocking substance to form a plug-shaped blocking object. The method of using the blocking device for blocking up obstacles in coelom is that the blocking substance in the coelom blocking device penetrates the obstacles in coelom, a near end of the guide wire is pulled, and the spread blocking substance is axially compressed to form a plug-shaped blocking object to block up the obstacles. The method for blocking up obstacle in coelom of the invention sets up a special coelom blocking device to block up and fix obstacles, such as thrombus and stone in coelom, and removes the obstacles according to practical requirements. The method for blocking up obstacle in coelom has tiny structure, simple operation, convenient use and high efficiency.

The instrument disclosed may comprise a tube assembly supporting an end effector that may be adapted for insertion into and through the urethra, and adapted for use in effecting the anastomosis of a patient's bladder and urethra following a prostatectomy. In one embodiment the end effector may comprise a positioner having an extendable and retractable petal operably connected to a tube, and an anchor driver. In another embodiment the end effector may comprise a positioner and an anchor driver having a driver pin operably connected to a tube.

An implantable biocompatible expander suitable for implantation into a urinary duct, comprises an elongated sinusoidal ring comprising at least two proximal prongs and at least two distal prongs, wherein the expander is resiliently deformable from a relaxed radially expanded orientation to a radially contracted orientation suitable for transluminal delivery through the urinary duct. The expander is configured to exert an outward radial force against a wall of the urinary duct when in-situ within the urinary duct. In particular, the expander is suitable for treatment of benign prostatic hyperplasia and configured for implantation into the prostatic urethra between, and substantially spanning the prostatic urethra between, the bladder neck and external sphincter.

The invention relates to an assembly comprising a support (1, 3, 4) for intervertebral prostheses and intervertebral prostheses (2) that are provided with different widths and are composed of two final plates (21, 22) with a ventral flange (23, 24) and an intermediate joint core (20). The support (1, 3, 4) is equipped with a base plate (10, 30, 40) which encompasses holes (12, 32, 42) for accommodating one of the intervertebral prostheses (2) and is larger than the maximum width of the intervertebral prostheses (2). A couple of steps (17) are embodied on at least one longitudinal edge (13) of the hole (12, 32, 42).; The facing sides (18) of said couple of steps (17) are disposed at a specific distance from each other so as to center the flange (24) of an intervertebral prosthesis (2) that is inserted into the hole (12, 32, 42), thus making it possible to insert intervertebral prostheses (2) having different widths into the holes (12, 32, 42) and retain the same in a centered position in the holes (12, 32, 42) regardless of the actual width thereof.

The instrument disclosed may comprise a tube assembly supporting an end effector that may be adapted for insertion into and through the urethra, and adapted for use in effecting the anastomosis of a patient's bladder and urethra following a prostatectomy. In one embodiment the end effector may comprise a positioner having a positioner arm that is extendable and retractable by rotation of a tube, and an anchor driver. In another embodiment the end effector may comprise a positioner and an anchor driver having a driver arm that is extendable and retractable by rotation of a tube.

The invention provides chitinase gene sequences and application of dsRNA thereof, which can silence specific chitinase genes and make insects die of retarded development. By cloning, sequencing and analyzing expression of the chitinase genes of a plurality of locusta migratoria manilensis, the chitinase genes with a sequence of SEQ IDNO:1 are obtained; and the chitinase genes with sequences of SEQ ID NO:2 and SEQ ID NO:3 are selected and used for synthesizing the dsRNA. After the dsRNA is injected into a coelom of an insect, the insect shows difficult molting in the development process and dies. The chitinase gene sequences provide a basis for the effective prevention and control of the insects based on RNA interference, and provide a new approach for the development of a safe and pollution-free method for preventing and controlling the insects.

An endoprostheses for implanting in a body lumen, such as a coronary artery, peripheral artery, or other body lumen includes a plurality of elongate strut members spaced apart and extending along a longitudinal axis, each elongate strut member having a plurality of alternating peaks and valley. At least one flexible connecting link connects each elongate strut member to an adjacent elongate strut member. The elongate strut members and connecting links forming a generally tubular stent body having a first delivery diameter and a second implanted diameter. The positioning of the connecting links along the stent body produces desired stent performance characteristics.

The instrument disclosed may comprise a tube assembly further comprising substantially coaxially situated and relatively longitudinally movable tubes, supporting and operating an end effector that may be adapted for insertion into and through the urethra, and adapted for use in effecting the anastomosis of a patient's bladder and urethra following a prostatectomy. In alternative embodiments the tube assembly may comprise a rod and two tubes, three tubes, a rod and three tubes, or four tubes. The method disclosed may comprise inserting an instrument having an end effector into the bladder lumen, and using the end effector to urge the bladder wall to the pelvic floor and drive an anchor through the bladder wall and into the pelvic floor.

The method disclosed may be used following a prostatectomy may comprise inserting an instrument having an end effector into the bladder lumen via the urethra; using the end effector to urge the bladder wall to the pelvic floor and drive an anchor through the bladder wall into the pelvic floor, thereby connecting a balloon harness within the bladder to the pelvic floor; withdrawing the end effector; inserting and inflating a balloon catheter within the balloon harness, thereby pressing the bladder wall surrounding the bladder opening against the pelvic floor; maintaining the balloon catheter in place and draining the bladder during the time required for the tissues to effectively knit; and then deflating and withdrawing the balloon catheter and disconnecting and withdrawing the balloon harness. The instrument may comprise one or more tubes that support an end effector comprising a positioner and an anchor driver.