90results about "Urethrae" patented technology

The present invention provides constructs including a tubular biodegradable polyglycolic acid scaffold, wherein the scaffold may be coated with extracellular matrix proteins and substantially acellular. The constructs can be utilized as an arteriovenous graft, a coronary graft, a peripheral artery bypass conduit, or a urinary conduit. The present invention also provides methods of producing such constructs.

A delivery device for positioning an implantable expander to a target location in a prostatic urethra. An implantable biocompatible expander suitable for implantation into a urinary duct is resiliently deformable from a relaxed radially expanded orientation to a radially contracted orientation suitable for transluminal delivery through the urinary duct. The expander may be configured to exert an outward radial force against a wall of the urinary duct when in-situ within the urinary duct. In particular, the expander is suitable for treatment of benign prostatic hyperplasia and configured for implantation into the prostatic urethra between, and substantially spanning the prostatic urethra between, the bladder neck and external sphincter.

Systems, devices, and methods are provided for the delivery of an implant into the prostatic urethra. Embodiments of delivery systems can include a delivery device for insertion into the patient and a proximal control device for use in controlling release of the implant from the delivery device.

A device for deploying an implant in a patient’s body comprises an elongate delivery tube 36 with tube elements in concentric relation in radial outward succession. The tube has an inner element compr

Aspects of the present invention relate to a delivery device for locating an expandable implant for treating BPH within the prostatic urethra of a patient. The delivery device comprises an inner tube and an outer sleeve movable relative to the inner tube between a stored position and a deployed position. The outer sleeve surrounds the inner tube to define an annulus therebetween and the expandable implant is retained within the annulus when the outer sleeve is in the stored position.

The present invention relates to a stent delivery device having: a first support rod into which a first movable body is inserted; a fixed magnet; and a second support rod into which a second movable body is inserted, wherein a first driving magnet included in the first movable body and a second driving magnet included in the second movable body rotate relative to each other by means of the control of an external magnetic field at a predetermined angle around an axis in a first direction with respect to the fixed magnet, thereby separating a first coupling piece and a second coupling piece from a first coupling groove and a second coupling groove and enabling a stent to unfold.

An implant with one or more sensors to measure fluid and tissues of the patient. The sensor may comprise a mechanical sensor configured to measure growth of a tissue such as BPH or a tumor. Alternatively or in combination, the implant may comprise one or more electrodes to stimulate tissue related to urinary urgency or male sexual function.

The invention relates to a device for draining urine from the bladder of a patient, comprising a retention component to be placed in the bladder and urethra and a retractable insertion aid of tubular or hose-like construction, which is placed in the retention component and is easy to insert or pass through the urethra, the inner lumen of the insertion aid offering the possibility of applying a lubricating and lumen straightening substance into the urethra, wherein a storage container for accommodating a preferably gel-like substance can be mounted on the proximal end of the insertion aid, the substance being able to be applied from an opening at the tip of the catheter through the insertion aid into the urethra without backflow into the proximal gap between insertion aid and catheter; furthermore, different embodiments of the device are described, as well as a method which not only enables the process of hole cover and cleaning preparation for the introduction of the catheter to be carried out by hand, but also allows the insertion of the catheter into the bladder to be carried out by guiding with only one hand of the user.

Disclosed are devices and methods for managing and / or treating bodily tissue obstructing a hollow body lumen, including prostatic lobe tissue obstructing the urethra, for example, health conditions including benign prostatic hyperplasia (BPH), bladder outlet obstruction (BOO), benign prostatic obstruction (BPO), and related lower urinary tract symptoms (LUTS). A retrieval sheath having an elongate shaft member with at least one region of altered flexibility configured to compress the implant to a reduced profile for removal from the patient's body.

A catheter for deploying an implantable expander in a urethra. An implantable biocompatible expander suitable for implantation into a urinary duct is resiliently deformable from a relaxed radially expanded orientation to a radially contracted orientation suitable for transluminal delivery through the urinary duct. The expander may be configured to exert an outward radial force against a wall of the urinary duct when in-situ within the urinary duct. In particular, the expander is suitable for treatment of benign prostatic hyperplasia and configured for implantation into the prostatic urethra between, and substantially spanning the prostatic urethra between, the bladder neck and external sphincter.

Some embodiments of the invention advantageously leverage the expansion of the prostatic urethra using adjustable lumen tension rings (ALTRs) of desired sizes to control and improve flow throughout the range of the urethra. As such, some embodiments include tension ring(s) or cylinders that sits either inside or outside the prostatic wall and is at least partially within the lumen and / or is partially or fully anchored, attached, adhered, or otherwise held in place with respect to the bladder or other locations within the urethra and / or elsewhere in the urethra. The expansion of the lumen can be pre-configured based on pre-operative metrology of the prostatic urethra to a customized and adjustable fit across the various zones within the urethra and based on the patient specific and evolving needs.

It is an object of the disclosed technique to provide methods and systems for a stent device, such as a prostatic urethral implant, for treating prostate enlargement and a constriction of the prostatic urethra while also maintaining the bladder neck and internal urethral sphincter unobstructed.

A stent is disclosed that is configured to maintain patency of the prostatic urethra despite an enlarged prostate. The stent can include a handle that, in an undeflected position, is disposed outside of the flow path of the stent. When the handle is pulled, the handle can deflect to generally aligned with a central axis of the stent. A capture device is disclosed that includes a tapered tip to navigate a working channel of a delivery device and a hook that can capture the stent handle and be moved into a tube to retain the stent handle to facilitate maneuvering of the stent in and out of the working channel of the delivery device. A loading adapter with a tapered port is disclosed that can be disposed on the delivery device to distribute compressive forces applied by the port on the stent during loading into the working channel.

To create an implant that allows for easy and reliable treatment of the bladder neck. [Solution] This is achieved by an implant having a pressurizing means structure for expanding the bladder neck of a person, particularly a removable implant. This pressurizing means structure applies local pressure to the tissue of the bladder neck. The pressurizing means structure may be connected to a retaining means for operation. This retaining means may be a wire, thread, or rod, and the retaining means is used to insert the implant or pressurizing means structure into the bladder neck via the urethra, and, if necessary, to retrieve the pressurizing means structure from the patient's body after the treatment is completed.

Implant (1, 10, 14) or catheter for insertion into the urethra (2) of a patient, with a through-opening (4) for the passage of urine, wherein a tube (5, 11, 15) made of an elastomer, having a lumen (6) for the passage of urine, is arranged in the through-opening (4), the wall thickness of which is so thin that the tube (5, 11, 15) can be set into vibration when urine flows through it.

A urethral endoscope for antegrade insertion of a. stent is disclosed. The urethral endoscope and method may provide optics at the time of inserting and positioning a urethrai stent. A deployment system is configured to hold simultaneously an implant and an optical system facilitating direct insertion of the implant into the desired area. In some embodiments, this facilitates insertion of the implant without first inserting the implant into the bladder and / or pulling the implant back from the bladder into the urethra. Some embodiments may facilitate insertion of an implant with a reduced number of insertions and removals of the endoscope and / or a. sheath thereof.

The invention creates an implant with which a bladder neck can be treated in a simple and reliable manner. This is achieved by an implant, in particular a removable implant, having a pressure means structure for expanding the bladder neck of a person. This pressure means structure exerts local pressure on the tissue of the bladder neck. The pressure means structure can be connected to a holding means for handling. This holding means, which may be a wire or a thread or a rod, can be used to insert the implant or the pressure means structure through the urethra into the bladder neck and, if necessary, to retrieve the pressure means structure from the patient's body after the end of the treatment.

An embodiment in accordance with the present invention provides a device and method for the treatment of urethral stricture. The present invention places and holds a graft at an incised urethral stricture site for 5-21 days, while the graft adherences to the incised urethral stricture site. A device of the present invention includes a delivery component, a graft carrier component, and a removal component. In some embodiments, the delivery and removal components may be combined into the same device. The delivery component, the graft carrier component, and the removal component are all configured to enter and exit the urethra without trauma. A method according to an embodiment of the present invention includes harvesting a graft, loading the graft onto the graft carrier component, introducing the delivery device into the urethra with the graft carrier component and graft loaded, and delivering of the graft to the incised urethral stricture site.

A stent configured to maintain patency of the prostatic urethra despite prostatic hyperplasia is disclosed. The stent may include a handle disposed outside the stent flow path in an undeflected position. When the handle is pulled, the handle may deflect to generally coincide with the central axis of the stent. A capturing device is disclosed that includes a tapered tip for moving through the working channel of a delivery device and a hook that can capture the stent handle and move within the tube to hold the stent handle and facilitate manipulation of the stent in and out of the working channel of the delivery device. A loading adapter with a tapered port that can be positioned on a delivery device to distribute compressive forces exerted by the stent port during loading into the working channel is disclosed.

The present invention relates to a medical device (100) for use as a ureteral stent, a biliary stent or a urinary catheter in a human or animal body. The medical device (100) comprises a hollow device body (101) having at least one body lumen (102), an inner body surface (105) and an outer body surface (106), wherein the inner body surface (105) delimits the at least one body lumen (102). The medical device (100) further comprises at least one array (110) of microstructures (111) located on the inner body surface (105) and / or the outer body surface (106) and configured to locally increase fluid-induced shear stress acting on the device body (101) in use of the medical device (100) in response to applying an acoustic field to the medical device (100). The invention further relates to a medical system comprising such as a medical device and an activation device configured to be positioned externally of a human or animal body, wherein the activation device comprises at least one sound transducer configured to generate an acoustic field for application from externally of the human or animal body to the medical device. The invention further relates to as to a method of acoustically activating such a medical device during use in a human or animal body, in particular for cleaning purposes and / or mass transport.

A device for maintaining patency of a prostatic urethra includes a stent having a proximal end, a distal end, and a passageway therebetween. The device includes longitudinal and angled struts and nodes, each longitudinal strut coupled to at least one angled strut at a corresponding node, the struts and nodes coupled to each other to form a plurality of cells, circumferentially adjacent cells forming stent regions. The stent includes a nose region, a body region, and a tail region. The stent is configured to expand from a compressed configuration to an expanded configuration within a bodily lumen. The stent includes a collapsibility gradient along its length such that it provides a nose region radial force at the nose region, a body region radial force at the body region, and a tail region radial force at the tail region, wherein the nose region radial force is less than the tail region radial force, and the tail region radial force is less than the body region radial force.

A catheter for deploying an implantable expander to a target location in a urethra. An implantable biocompatible expander suitable for implantation into a urinary duct is resiliently deformable from a relaxed radially expanded orientation to a radially contracted orientation suitable for transluminal delivery through the urinary duct. The expander may be configured to exert an outward radial force against a wall of the urinary duct when in-situ within the urinary duct. In particular, the expander is suitable for treatment of benign prostatic hyperplasia and configured for implantation into the prostatic urethra between, and substantially spanning the prostatic urethra between, the bladder neck and external sphincter.

A prostatic implant configured to compress an enlarged prostate gland includes a distal anchor member and an expandable, proximal anchor member connected by a middle portion. The expandable, proximal anchor member is configured to expand upon being released from a tubular delivery device, such that the anchoring footprint of the expandable anchor member on the urethral side of a prostate gland is large relative to anchors having fixed dimensions. The expandable anchor member includes expandable portions configured to expand outwardly or laterally away from the body of the expandable anchor member, forming curved portions or wings. After anchoring the distal anchor member to the outer surface of the prostatic capsule, tension may be applied to the middle portion extended through the prostate gland. Attachment of the expandable anchor member to the middle portion at the urethral side of the gland locks the tension in place, retracting the enlarged prostatic tissue.

A device (100) having a proximal end (10) and distal end (20) for delivery of a graft sheet (450) for deployment and attachment to a target within a tubular vessel (400), wherein the device (100) comprises a delivery head (200) configured for passage through the tubular vessel (400) of the subject, wherein the delivery head (200) comprises: a holding element (220) comprising a slot (222) open at least at its proximal (10) end, configured for slidable receiving of and retention of the graft sheet (450) for presentation to the target; a coupling element (260) configured for slidable attachment to a delivery tube (310) of a tacker device, wherein the tacker device is configured to deliver and deploy a tack from a terminal distal (20) end of the delivery tube (310) for attaching the graft sheet (450) to a vessel lumen interior wall (404) of the tubular vessel (400) of the subject; wherein: the coupling element (260) is configured to rotate around a single axis (262) of rotation relative to the holding element (220); the single axis (262) of rotation is disposed in fixed relation to the holding element (220); and rotational movement of the coupling element (260) around the single axis (262) of rotation to a deployment position of the coupling element (260) directs a distal end (20) of the coupling element (260) towards the slot (222).

An implant with which a bladder neck can be treated in a simple and reliable manner. This is achieved by an implant, in particular a removable implant, having a pressure structure for expanding the bladder neck of a person. This pressure structure exerts local pressure on the tissue of the bladder neck. The pressure structure can be connected to a holding for handling. This holding, which may be a wire or a thread or a rod, can be used to insert the implant or the pressure structure through the urethra into the bladder neck and, if necessary, to retrieve the pressure structure from the patient's body after the end of the treatment.

Systems, devices, and methods are provided for the delivery of an implant into the prostatic urethra. Embodiments of delivery systems can include a delivery device for insertion into the patient and a proximal control device for use in controlling release of the implant from the delivery device.

An implant with which prostates of different sizes can be treated is achieved by the fact that the length of a deployed implant is modifiable to a variable extent. Through the change of length of a stretched-out wire structure of the implant, the implant can be adapted individually to the patient anatomy and the outcome of treatment can thus be improved.

Systems, apparatus, and methods for delivering an implant into the prostatic urethra are provided. Embodiments of the delivery system may include a delivery device for insertion into a patient and a proximal control device for controlling the release of the implant from the delivery device.

A delivery device for image-assisted delivery of an implantable expander in a urethra. An implantable biocompatible expander suitable for implantation into a urinary duct is resiliently deformable from a relaxed radially expanded orientation to a radially contracted orientation suitable for transluminal delivery through the urinary duct. The expander may be configured to exert an outward radial force against a wall of the urinary duct when in-situ within the urinary duct. In particular, the expander is suitable for treatment of benign prostatic hyperplasia and configured for implantation into the prostatic urethra between, and substantially spanning the prostatic urethra between, the bladder neck and external sphincter.

A stent for insertion into the lumen of an anatomical vessel or duct including a helical coil embedded in a polymer tube. The helical coil includes expandable part, which is able to be in a compressed or expended configuration. The polymer tube is radially rigid to prevent reduction of the diameter of the turns of the helical coil when the stent is twisted.