60 results about "Urethral sphincter" patented technology

An urethral drain having deep external drainage channels, a low-profiled bladder retention segment, and a reversibly detachable collection segment, facilitates the draining of urine and fluids from the bladder. The low-profiled retention means minimizes bladder irritations and the deep external channels reduce the occurrence of infections. Incorporation of a reduced diameter smooth segment on the catheter, proximate the location of the external urethral sphincter allows the patient to void normally and at will. Modifying the size of this smooth segment aids the function of a defective sphincter in controlling urine leakage. The drain can be worn concealed within the urethra. Flushing action from normal voiding washes out particulate matters in the urethra and the concealed drain further minimizes contamination. Together, these features improve quality of life for patients needing catheterization.

A disposable, inexpensive instrument is provided with the aim to facilitate an injection of bulk enhancing agent into the urethral sphincter. An idea of a balloon of Foley's catheter has been exploited where the balloon acts as a retainer immobilizing the instrument in a desired position inside the bladder during the injection. The instrument has a shape of an elongated shaft with a multitude of curved channels guiding and deflecting the needle to an appropriate angle, depth of penetration and exact location on the sphincter during the injection.

It is an object of the present invention to provide a method and apparatus for enhanced bladder voidance which would have the advantages of a rhizotomy yet be temporary and reversible by combining low and high-frequency sacral nerve stimulation. Applicants propose a new sacral neurostimulation strategy based on a combination of nerve conduction blockade using high frequency signals and nerve stimulation using low-frequency signals. The method and apparatus enhances micturition in paraplegics by sacral neurostimulation involving a combination of a low-frequency electrical stimulation applied to one or more sacral nerves to induce bladder contraction and a high frequency electrical stimulation applied to at least one sacral nerve to cause nerve conduction blockade that prevents urethral sphincter dyssynergic contraction.

A method and system for bladder control are disclosed. In embodiments, a method for bladder control is provided that comprises coupling an electrode to an afferent nerve that is related to the bladder. Applying a plurality of pulse burst stimulations via the electrode causes voiding of urine from the bladder. In embodiments, the plurality of pulse burst stimulations to the afferent nerve reduces external urethral sphincter (EUS) contractions and evokes bladder contractions to expel urine from the subject. In embodiments, the plurality of pulse burst stimulations to the afferent nerve evokes bladder contractions alone to expel urine from the subject. In embodiments, a system for bladder control is provided that comprises an electrode for applying a pulse burst stimulus to an afferent nerve or dermatome to reduce reflex contractions and a signal generator for generating the pulse burst stimulus.

An apparatus for treating urinary incontinence comprises an electrically powered stimulation device that electrically stimulates the urethral sphincter of a urinary incontinent patient and a hand-held wireless remote control that controls the stimulation device. A stress or urge incontinent patient operates the remote control to: i) switch off the electrically powered stimulation device, when the patient wants to urinate, and switch on the electrically powered stimulation device, when the patient has finished urinating; and ii) control the stimulation device as needed at any time over the course of a day to promptly adjust the intensity of the electric stimulation of the urethral sphincter to quickly increase the tonus of the urethral sphincter.

The invention relate to the demonstration herein that it is feasible to use a transvaginal NIRS probe to interrogate functioning urological tissues, such as the urethral sphincter, the bladder detrusor muscle, and pelvic floor musculature, to obtain clinically relevant information. The present invention accordingly provides methods and devices for transvaginal monitoring or imaging of the urological tissues, such as the urethral sphincter and/or the bladder, and/or pelvic floor musculature, using NIRS.

The invention discloses a double balloon positioning prostatic capsule expansion and prostatic capsule tissue splitting displacement catheter which comprises a catheter main body; a urinary catheterization cavity, a flushing cavity, a front balloon cavity and a rear balloon cavity are arranged in the catheter main body; the four cavities are provided with front end openings respectively; the front balloon cavity is formed in the rear parts of the front end openings of the urinary catheterization cavity and the flushing cavity; the rear balloon cavity is formed in the rear part of the front balloon cavity in parallel; the front end openings of the urinary catheterization cavity are two holes; the front end opening of the flushing cavity is a single hole; the length of the front balloon cavity is 38 cm; the outside diameter of the front balloon cavity and the rear balloon cavity are 3.2-3.9 cm when the front balloon cavity and the rear balloon cavity are filled up. The catheter is characterized in that the front balloon cavity and the rear balloon cavity are barrel-shaped after being filled up; the length of the front balloon cavity is equal to or larger than that of the rear balloon cavity; the outside diameter of the catheter main body is 0.6-0.8 cm. The catheter has the advantages that the requirement and selection of various hyperplastic prostate treatment can be met, especially the requirements of patients with apex of prostate exceeding verumontanum and external urethral sphincter. The catheter is made of TPU, and has the advantages of being high in pressure resistance, shapable, high in tightness, soft, smooth and transparent.

A urinary apparatus includes a catheter system for pressurizing either a bladder cavity or a urethral canal within a female urinary system and an endoscope device for observing a urethral sphincter muscle within the female urinary system for assessing the sling tension of an implant support adapted to restore female urinary continence. The catheter system includes a obturator occlusion member for plugging the urethral canal during the performance of a sling tensioning procedure.

An implantable device arranged to contact the urethral sphincter allows for manipulation of the device from outside the body by the patient.

The present invention relates to a cellular therapeutic agent for treating urinary incontinence, and more particularly to a cellular therapeutic agent for treating urinary incontinence, which contains stem cells derived from the decidua of the placenta or menstrual fluid or stem cells derived from adipose. The decidua-derived stem cells or adipose-derived stem cells show the effects of increasing leak point pressure and urethral sphincter contractility, and thus are useful as an agent for treating urinary incontinence.

Amyotrophic lateral sclerosis (ALS) is a devastating disease that leads initially to death of motor nerves with some progression to death of sensory and autonomic nerves. Experimental work shows that more electrical energy is required to successfully stimulate motor vs. sensory nerve components of a nerve and longer vs. shorter components of a nerve. This discovery explains sparing of the nerves of ocular motion and nerves of rectal and urethral sphincters in patients suffering from ALS and supports the energy hypothesis of ALS. Neurons and peripheral nerves are dependent upon glial cells and oligodendrocytes respectively to support their high energy demands. These supporting cells shuttle lactate to neurons and nerves. Lactate is required to sustain contraction of skeletal muscle. Administration of racemic or L-lactate in an amount greater than the capacity of the liver to oxidize will increase the available lactate to nerves and neurons and improve the symptoms of ALS.

The present invention relates to lower urinary dysfunctions and more particularly to an electronic stimulator implant and method to improve bladder voiding and prevent bladder hyperreflexia. There is provided an electronic stimulator implant for which comprises a tonicity signal generator generating a tonicity signal which prevents bladder hyperreflexia combined with a voiding signal generator generating a voiding signal for voiding the bladder. The implant is connected to an end of an electrode, and the second end thereof is connected to a sacral nerve. When the voiding key (or switch) is activated, the voiding signal is generated which activates detrusor muscle contraction, causing bladder voiding. The voiding may be achieved without dyssynergia, by activating detrusor muscle contraction without activating external urethral sphincter contraction. The tonicity signal may be provided intermittently. The implant may be activated by a manually activated external controller.

The invention provides a prostatic enucleation scope for carrying out blunt dissection and enucleation of prostatic tissue, comprising a viewer body and an enucleation rod juxtaposed from top to bottom; a fiber passage is arranged in the enucleation rod and may extend out of the insert end of the enucleation rod; an optical fiber is arranged in the fiber passage; the insert end of the enucleationrod is provided with an enucleation head that is of duckbill structure; the enucleation head is connected with a handle arranged at the non-insert end of the enucleation rod; the enucleation head canbe controlled to open or close via the handle. The prostatic enucleation scope also comprises a sheath that sleeves the viewer body and the enucleation rod; the middle of the sheath is provided with an instrument passage; the wall of the sheath is of double-layer structure; a gap is arranged in the wall of the sheath; the insert end of the sheath is provided with a plurality of holes. The prostatic enucleation scope herein can effectively prevent injury of a patient's urethral sphincter due to long-term compression, and can provide timely hemostasis during prostatic dissection for the patientso that surgical treatment is facilitated and surgical time is effectively shortened.

The invention discloses a silk fibroin/stem cell compounded microsphere and application thereof. The silk fibroin/stem cell compounded microsphere is prepared with the following method: silk fibroin microsphere suspension and stem cell suspension are sufficiently mixed, and then placed in a sterile culture dish and cultured in a cell incubator in conditions that the temperature is 37 DEG C, CO2 content is 5 percent, and the saturated humidity is 100 percent, a culture solution is changed every 3 days, and culture is performed till silk fibroin microsphere and stem cells are compounded to form a cell microsphere. Urethra tissue engineering filler constructed through an ADSCs composite silk fibroin microsphere is used for curing SUI rat, on one hand, by injecting the silk fibroin microsphere, supporting and filling are provided for vesical necks, and an instant treatment effect is produced; on the other hand, regeneration of local muscle and nerves is promoted and the structural and functional defects of urethral sphincter are improved through the transplantation of ADSCs compounded on the silk fibroin microsphere and subsequent cell differentiation and multiplication to improve the urine control ability of urethral sphincter, so that the lasting treatment effect is achieved.