10 results about "Tissue augmentation" patented technology

Surgical constructs, assemblies, kits and methods of tissue fixation are disclosed. Soft tissue augmentation is conducted with a simple device that allows a surgeon to augment poor tissue in a most expedient and straightforward manner. The device includes an implant in the form of a molded part which has one or more barbs that are angled generally in a retrograde fashion. The implant is affixed to the graft desired to be augmented onto patient's tissue. The surgeon needs only “hook” the distal portion of the graft / implant device into patient's tissue and pull to fix the graft in contact.

The present disclosure provides a 3D tissue reconstruction implant having a hydrophilic implant surface and consisting of a bioabsorbable material wherein the implant surface is considered hydrophilic when evaluated using an ink test that follows ISO 8296: 2003 and adapts to the 3D surface, and wherein the implant surface is not hydrophilic when evaluated using an ink test that follows ISO 8296: 2003 and adapts to the 3D surface. Wherein the ink test comprises incubating the implant in a solution consisting of an ink having a surface tension of 72 mN / m and water for 1 minute, and wherein after the implant is incubated in the solution, the ink colored implant surface is an indication of a hydrophilic implant surface. The disclosure also provides the implant for tissue reconstruction, (soft) tissue support, tissue compatibilization and / or implant repair, and the use of the implant for reconstruction, compatibilization and / or repair of tissue and / or support of (soft) tissue, respectively, where the implant is embedded in a patient. The present disclosure further provides a method of manufacturing a tissue reconstruction implant having a hydrophilic implant surface.

Provided herein is an injectable composition including, in some embodiments, a soft-tissue augmenting agent and a vehicle for the soft-tissue augmenting agent formulated for augmenting one or more soft tissues of a human or animal. Also provided herein is a soft-tissue augmenting kit including, in some embodiments, a syringe and the injectable composition formulated for augmenting one or more soft tissues of a human or animal. Also provided herein is a method for augmenting one or more soft tissues of a human or animal including, in some embodiments, injecting the injectable composition into the one or more soft tissues of the human or animal.

This invention is entitled "Tissue-Reinforcing Scaffold for Use in Soft Tissue Fixation and Repair." The invention provides apparatus, systems, and methods for improving the reliability and speed of soft tissue repair surgery. The apparatus and systems include one or more tissue-reinforcing constructs comprising structures configured to increase the coverage area on the tissue by which the sutures exert force when tightened to the tissue. The tissue-reinforcing constructs can be quickly and easily associated with the repair sutures and can be used in many different tissue repair procedures disclosed in this application. The tissue-reinforcing constructs may include various blocks and scaffolds, as well as other shaped structures. Among other disclosures, this disclosure includes methods for using tissue-reinforcing scaffolds including folded scaffolds, and descriptions and methods associated with ultra-wide tissue-reinforcing blocks.

Disclosed herein are tissue augmentation compositions comprising a hydrogel modified with methacrylic anhydride. The hydrogel may be composed of albumin, collagen, silk, or keratin. The composition may be used to modulate an immune response for tissue augmentation and / or as a dermal filler. The composition is non-immunogenic, non-toxic, and may be used for various biomedical applications, including passivation coatings for biomedical devices, depots, and inserts.

Provided herein is an injectable composition including, in some embodiments, a soft-tissue augmenting agent and a vehicle for the soft-tissue augmenting agent formulated for augmenting one or more soft tissues of a human or animal. Also provided herein is a soft-tissue augmenting kit including, in some embodiments, a syringe and the injectable composition formulated for augmenting one or more soft tissues of a human or animal. Also provided herein is a method for augmenting one or more soft tissues of a human or animal including, in some embodiments, injecting the injectable composition into the one or more soft tissues of the human or animal.

Surgical constructs, assemblies, kits and methods of tissue fixation are disclosed. Soft tissue augmentation is conducted with a simple device that allows a surgeon to augment poor tissue in a most expedient and straightforward manner. The device includes an implant in the form of a molded part which has one or more barbs that are angled generally in a retrograde fashion. The implant is affixed to the graft desired to be augmented onto patient's tissue. The surgeon needs only "hook" the distal portion of the graft / implant device into patient's tissue and pull to fix the graft in contact.

Disclosed herein are tissue augmentation compositions comprising a hydrogel modified with methacrylic anhydride. The hydrogel may be composed of albumin, collagen, silk, or keratin. The composition may be used to modulate an immune response for tissue augmentation and / or as a dermal filler. The composition is non-immunogenic, non-toxic, and may be used for various biomedical applications, including passivation coatings for biomedical devices, depots, and inserts.

The present invention relates to a dermal filler for soft tissue augmentation comprising 85-99% water and 1-12% microbial cellulose wherein the said cellulose is Acetobacter xylinum fermented in coconut milk culture media. The microbial cellulose is reduced to a nano particle having a diameter predominantly 100 nm and has a nano porous mesh structures and fibrils aggregate forming tunnels in between the microbial cellulose fibers for gaseous and fluid exchange; has a high cellulose crystallinity (60-80%) and has an enormous mechanical strength for the extended biodegradability, and biocompatibility. Said microbial cellulose has a preservative in the form of a natural coconut derived active ingredient where monolaurin is present in the amount of 1%. It is pure, natural, hydrophilic and characterized by the absence of lignin. It can be easily injected and pass through a gauge 30 needle with minimal reaction and discomfort at the site of the injection. It is safe and has a porosity benefit which makes it more permeable and penetrable for effective tissue augmentation and aesthetic correction of wrinkles or loss of muscle volume including nasolabial furrow, wrinkled cheeks, deep smile lines and lipoatrophy correction. It is non¬ phototoxic, no toxicity and safe on the area around the eyes (Optisafe). It can be administered intradermally or sub-epidermally. The cellulose suspension is packed in glass vials of 3 ml, 8%, 10% and 12% concentration.

Devices, systems, and methods to improve both the reliability of soft tissue repair procedures and the speed at which the procedures are completed are provided. The devices and systems include one or more tissue augmentation constructs, which include constructs that are configured to increase a footprint across which suture applied force to tissue when the suture is tied down onto the tissue. The tissue augmentation constructs can be quickly and easily associated with the repair suture, and can be useful in many different tissue repair procedures that are disclosed in the application. In one exemplary embodiment, one or more constructs are disposed on a suture threader, which can be used to associate the construct(s) with a repair suture(s) being used to repair the soft tissue. Tissue augmentation constructs can include various blocks and patches, among other formations. Exemplary methods for manufacturing the tissue augmentation constructs are also provided.