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43 results about "Paralysis" patented technology

Loss of muscle function in one or more muscles.

Systems and / or methods for assessing neuromuscular block status without stimulation

Neuromuscular block characterization techniques are disclosed. A muscle movement measurement device generates, unprompted by impulse stimulation to a subject from an external source, at least one signal representative of muscle movement measurements at at least one location of a body of the subject while the subject is experiencing neuromuscular paralysis caused by biophysiological processes at neuromuscular synapses throughout the body including remote from the at least one location. A processing circuit runs a neuromuscular block analysis module that receives the at least one signal, analyzes the muscle movement measurements embedded in the at least one signal, and determines a degree of neuromuscular blockade associated with the neuromuscular paralysis being experienced by the subject. The processing circuitry further generates, for display via a display device, an indication of the degree of the neuromuscular blockade at each said location on the body.
Owner:BLOCKSYNOP INC

Alternating current auxiliary system for generating Chinese text based on electroencephalogram

PendingCN120763679ABiological modelsSignal classificationAsymptomatic Diseases
The invention belongs to the technical field of electroencephalogram signal processing, and particularly relates to an alternating current auxiliary system for generating a Chinese text based on electroencephalogram. The system comprises: an input module configured to input an electroencephalogram signal; and the electroencephalogram signal classification module is configured to input the electroencephalogram signals into a classification model to obtain a classification result of phonetic alphabets. In order to further generate the Chinese text, the system can further comprise a Pinyin input method module which is configured to convert the classification result of the Pinyin letters into the Chinese text through a Pinyin input method. The Chinese text generated by the system and the method has the characteristics of high efficiency and accuracy, is greatly helpful for communication demands of paralysis, aphasia and asymptomatic diseases caused by stroke, and has a good application prospect.
Owner:CHENGDU TECH UNIV

Dog lifting device

This invention discloses a dog lifting device (10) for animals particularly for big breed canine or dogs as a support during medical or surgical procedures but more particularly to a dog lifting device (10) which permits large and heavy dogs to be lifted with relative ease during periods of medical and surgical procedures, temporary or permanent paralysis. The dog lifting device (10) comprises a frame (12), a motored hoist (22) secured to the frame (12), an actuator (24) connected to the motored hoist (22) and a lifting rope (26) operably connected to the actuator (24) with a pulley (26) that translates the horizontal force from the motored hoist (22) to the lifting rope (26) which makes the dog lifting device (10) efficient, safe and easy to use with due regard to animal welfare.
Owner:ELESTWANI MARIAM

HERV-k (HML-2) ENV analog fusion proteins for antigen specific immunotherapy and methods of use

ActiveUS20260035414A1Nervous disorderAntibody mimetics/scaffoldsDiseaseMuscular weakness
The present disclosure provides recombinantly manufactured fusion proteins comprising a HERV-K (HML-2) Env protein fragment or an analog thereof linked to a human Fc fragment. Embodiments include the administration of the fusion proteins to patients having a disease or a disorder with the intention of mitigating and / or reducing the duration of symptoms associated with the condition or disease (for example but not limited to muscular weakness, paralysis and respiratory failure), and / or preventing symptoms associated with the condition or disease, for example, by preventing motor neuron degeneration and cell death in ALS patients associated with the condition or disease. Accordingly, “treatment” generally means both therapeutic treatment and prophylactic or preventative measures. Improvement after treatment may be manifested as a decrease or elimination of such symptoms, e.g., by a decrease or elimination of symptoms associated with ALS, and / or by a decrease in the duration of such symptoms.
Owner:TWILIGHT BIOSCIENCE INC

HERV-k (HML-2) ENV analog fusion proteins for antigen specific immunotherapy and methods of use

PCT designated stageWO2026030596A1Nervous disorderCell receptors/surface-antigens/surface-determinantsDiseaseMuscular weakness
The present disclosure provides recombinantly manufactured fusion proteins comprising a HERV-K (HML-2) Env protein fragment or an analog thereof linked to a human Fc fragment. Embodiments include the administration of the fusion proteins to patients having a disease or a disorder with the intention of mitigating and / or reducing the duration of symptoms associated with the condition or disease (for example but not limited to muscular weakness, paralysis and respiratory failure), and / or preventing symptoms associated with the condition or disease, for example, by preventing motor neuron degeneration and cell death in ALS patients associated with the condition or disease. Accordingly, "treatment" generally means both therapeutic treatment and prophylactic or preventative measures. Improvement after treatment may be manifested as a decrease or elimination of such symptoms, e.g., by a decrease or elimination of symptoms associated with ALS, and / or by a decrease in the duration of such symptoms.
Owner:TWILIGHT BIOSCIENCE INC

Auxiliary rehabilitation device for limb paralysis

The invention discloses an auxiliary rehabilitation device for limb paralysis, which comprises a clamping mechanism used for being clamped on a bed or a chair; the number of the fixing mechanisms is two, the two fixing mechanisms are used for being arranged on limbs in a sleeving mode, each fixing mechanism comprises a fixing ring, an air bag and an air supply assembly, the air bags are arranged along the inner walls of the fixing rings, and the air supply assemblies communicate with the air bags; the clamping mechanism is connected with the two fixing rings through the posture adjusting mechanism, the posture adjusting mechanism is used for adjusting the space positions of the two fixing rings so as to adjust the posture of the limbs, and the gas supply assembly is installed on the posture adjusting mechanism. The rehabilitation training device can be used for upper limb rehabilitation training and lower limb rehabilitation training, a patient can lie or sit, and the rehabilitation training device is suitable for full-paralyzed or semi-paralyzed patients, flexible and convenient to use and high in universality.
Owner:THE SECOND AFFILIATED HOSPITAL OF GUANGXI MEDICAL UNIV

Meridian warming and activating traditional Chinese medicine compound for treating facial paralysis and preparation method thereof

The invention provides a meridian warming and activating traditional Chinese medicine compound for treating facial paralysis and a preparation method thereof, and belongs to the field of traditional Chinese medicine treatment of facial paralysis. The meridian-warming and collateral-dredging traditional Chinese medicine compound follows the compatibility theory of monarch, minister, assistant and guide in traditional Chinese medicine, is rigorous in composition, and has the effects of warming and dredging meridians, dispelling wind, reducing phlegm, reinforcing qi and nourishing blood aiming at the pathogenesis of facial paralysis, such as wind-cold attacking collaterals, unsmooth qi and blood and deficiency of vital qi, so as to achieve the effects of harmonizing yin and yang and strengthening body resistance to eliminate pathogenic factors. The traditional Chinese medicine composition has a good curative effect on Bell facial paralysis caused by wind-cold invasion and meridian blockage, and the symptoms of sudden oblique mouth and eyes, facial numbness, incomplete eye closure, frontal line disappearance and the like. Contrast experiments prove that the total treatment effective rate of the meridian-warming and collateral-dredging pill is obviously higher than that of mecobalamine tablets and prednisolone acetate tablets, and the meridian-warming and collateral-dredging pill has more obvious effects on relieving the severity of facial paralysis and improving the score of facial paralysis. Therefore, the meridian-warming and collateral-dredging pill shows a good clinical curative effect in the aspect of treating the wind-cold arthralgia type bellar paralysis, and is expected to provide a better choice for clinical treatment of the wind-cold arthralgia type bellar paralysis.
Owner:THE SECOND AFFILIATED HOSPITAL OF ANHUI UNIVERSITY OF TRADITIONAL CHINESE MEDICINE (ACUPUNCTURE AND MOXIBUSTION HOSPITAL OF ANHUI PROVINCE)

System for detecting exercise intention of user and controlling functional electrical stimulation (FES) according to same

The present application relates to a rehabilitation system based on brain-computer interface (BCI) and functional electrical stimulation (FES) technology. Specifically, the present application relates to a system for detecting a user's exercise intention and promoting recovery of lower extremity functions through electrical stimulation according to same, and relates to a rehabilitation and assistance system for impaired persons suffering from paralysis or complete paralysis of the lower extremities. According to the present application, neural signals due to motor imagery of a user are analyzed in real time, and electrical stimulation is applied to a specific muscle group on the basis thereof to improve motor function.
Owner:KOREA INST OF SCI & TECH

Systems for inhibiting heterotopic ossification

ActiveUS12508374B2Surgical needlesAutomatic syringesMuscle tissueNeuromuscular inhibition
Systems for treating a targeted volume of muscle tissue to inhibit heterotopic ossification (HO) employ a delivery device including a reservoir containing a neuromuscular inhibitor and an injector assembly. The injector assembly can include an arrangement of needles and an injector operable to pass the neuromuscular inhibitor from the reservoir through the needles. The injector assembly can be configured to eject predetermined aliquots of a therapeutic dose of the neuromuscular inhibitor. The injector assembly can be shaped to compliment the targeted volume of muscle tissue within a larger volume of muscle tissue. The ejection of the predetermined aliquots can result in a therapeutic distribution of the therapeutic dose of the neuromuscular inhibitor within the targeted volume of muscle tissue that is sufficient to prevent formation of an HO lesion but insufficient to induce paralysis of the larger volume of muscle tissue.
Owner:UNIV OF WASHINGTON

HERV-k (HML-2) ENV analog fusion proteins for antigen specific immunotherapy and methods of use

PendingUS20260035415A1Antibody mimetics/scaffoldsVirus peptidesDiseaseMuscular weakness
The present disclosure provides recombinantly manufactured fusion proteins comprising a HERV-K (HML-2) Env protein fragment or an analog thereof linked to a human Fc fragment. Embodiments include the administration of the fusion proteins to patients having a disease or a disorder with the intention of mitigating and / or reducing the duration of symptoms associated with the condition or disease (for example but not limited to muscular weakness, paralysis and respiratory failure), and / or preventing symptoms associated with the condition or disease, for example, by preventing motor neuron degeneration and cell death in ALS patients associated with the condition or disease. Accordingly, “treatment” generally means both therapeutic treatment and prophylactic or preventative measures. Improvement after treatment may be manifested as a decrease or elimination of such symptoms, e.g., by a decrease or elimination of symptoms associated with ALS, and / or by a decrease in the duration of such symptoms.
Owner:TWILIGHT BIOSCIENCE INC

Female urine device (flushable urine receiving portion)

ActiveCN309555338SArtificial urineFrail Older Adults
1. Name of the design product: female urine collector (washable urine receiving part) 2. Use of the design product: the design product is a urine receiving part for a urine collector, which is suitable for female patients with paralysis, incontinence and the elderly with difficulty in movement, and is worn in a sitting or lying position, simulates artificial urine receiving mode, and has a perineal washing function. 3. Design points of the design product: shape. 4. Picture or photo that best shows the design points: perspective view. 5. The rear view is symmetrical with the front view, and the rear view is omitted.
Owner:TAKARADATE CO LTD

Gloves with zippers

We provide gloves with a zipper that make it easy to put on and take off five-finger gloves. [Solution] Open zipper 1 attached to the index finger side and zipper 2 attached to the little finger side of the five-finger glove all the way, fully extend the glove, and once the finger pockets are visible, insert your hand and make sure that your fingertips are securely in place, then close zippers 1 and 2. This reduces the time and effort required to put on and take off the gloves, and in particular, when assisting people with disabilities or paralysis, or their caregivers, to put on gloves, it reduces the effort of fumbling around to place each finger into the finger pocket, and allows for quick preparation.
Owner:大貫 圭子

HERV-k (HML-2) ENV analog fusion proteins for antigen specific immunotherapy and methods of use

PCT designated stageWO2026030590A1Nervous disorderAntibody mimetics/scaffoldsDiseaseMuscular weakness
The present disclosure provides recombinantly manufactured fusion proteins comprising a HERV-K (HML-2) Env protein fragment or an analog thereof linked to a human Fc fragment. Embodiments include the administration of the fusion proteins to patients having a disease or a disorder with the intention of mitigating and / or reducing the duration of symptoms associated with the condition or disease (for example but not limited to muscular weakness, paralysis and respiratory failure), and / or preventing symptoms associated with the condition or disease, for example, by preventing motor neuron degeneration and cell death in ALS patients associated with the condition or disease. Accordingly, "treatment" generally means both therapeutic treatment and prophylactic or preventative measures. Improvement after treatment may be manifested as a decrease or elimination of such symptoms, e.g., by a decrease or elimination of symptoms associated with ALS, and / or by a decrease in the duration of such symptoms.
Owner:TWILIGHT BIOSCIENCE INC

Artificial intelligence enhanced functional electrical stimulation for central nervous system disabilities

Provided herein are systems for treating a paralysis patient in need of controlled motion to improve quality of life, and related methods. The systems comprise an implantable system formed from a hub, various electrodes, such as spinal cord (upstream) electrode, periphery nerve (downstream) electrode and an external system formed of communication pod implanted just under the skin, a computing core, and a plurality of motion sensors. A software system, providing AI compatibility are used to supply the computing core, and thereby implanted electrodes, with signal. In this manner, the specially positioned electrodes, upstream of the spinal cord injury and downstream of the spinal cord injury, can provide safe and reliable patient motion.
Owner:NEURAL AUTOMATIONS LTD

Rehabilitation booster for paralysis of upper and lower limbs

The upper and lower limb paralysis rehabilitation booster comprises a base, an upper limb training assembly, a lower limb training assembly and a seat are arranged on the base, an adjusting groove is formed in the base in the length direction, an adjusting screw rod is rotationally connected into the adjusting groove, an adjusting block is in threaded connection with the adjusting screw rod, and the cross section of the adjusting block and the cross section of the adjusting groove are both square. The adjusting block is slidably connected into the adjusting groove, the seat is arranged on the adjusting block, an adjusting motor for driving the adjusting screw to rotate is arranged on the outer surface of the base, the adjusting screw drives the adjusting block to move along the adjusting groove, and the adjusting block moves to drive the seat to be close to or away from the training assembly. Therefore, the distance between the seat and the training assembly can be flexibly adjusted. The rehabilitation training device has the effect of improving the comfort of a patient during rehabilitation training.
Owner:TAICANG JINGQUAN METAL PROUDUCTS CO LTD

Tibetan medicine 56-site agate pill and preparation process thereof

The Tibetan medicine fifty-six agate pill is mainly prepared from fifty-six medicinal materials including zota, pearls, agate, fructus chebulae, semen myristicae, tabasheer and the like, and has the effects of restoring consciousness, inducing resuscitation, easing mental tranquility, clearing and activating the channels and collaterals, enriching blood, tonifying qi, building the body, prolonging life and enhancing the immunity of the organism. The traditional Chinese medicine composition is used for treating red pulse, black pulse and white pulse diseases caused by the longishi disease and three-cause (longishi, red pulse and bacon) imbalance, and cardiovascular and cerebrovascular diseases and nervous system diseases. The traditional Chinese medicine composition is suitable for diseases such as heart disease, Parkinson's disease, Alzheimer's disease, sleep disorder, hypertension, Meniere's syndrome, gastrointestinal diseases, stroke, paralysis, hemiplegia, ankylosing spondylitis, epilepsy, cerebral hemorrhage, cerebral concussion and gradual freezing; and various intractable diseases such as heavy metal detoxification are treated.
Owner:CHENGDU WUHOU GANLU HAIZANG HOSPITAL CO LTD

Auxiliary rehabilitation device for amyotrophy lateral sclerosis paralysis

The utility model relates to the technical field of medical rehabilitation training equipment, and discloses an amyotrophy lateral sclerosis paralysis auxiliary rehabilitation device which comprises two supports, a bed board is fixedly connected to the middles of the two supports, a protruding block is arranged on the left side of the top end of the bed board, and two sliding grooves are formed in the right side of the bed board. Sliding plates are slidably connected to the interiors of the sliding grooves, a positioning plate is fixedly connected to the top ends of the two sliding plates, two first hook-and-loop fasteners are fixedly connected to the left side of the positioning plate, a ring rod is fixedly connected to the bottom ends of the two sliding plates, and an inner ring is rotatably connected to the middle of the ring rod. According to the utility model, a family member can easily assist a patient in pedaling reciprocating training of feet. Through the training, the lower limb muscles of the patient can be effectively exercised, and in addition, the device can drive the upper limbs of the patient to stretch and contract, so that the upper limbs can be fully exercised.
Owner:THE AFFILIATED HOSPITAL OF SHANDONG UNIV OF TCM

Functional adjustable paralysis movable shifter

The utility model provides a functional adjustable paralysis movable shifter, and relates to the technical field of medical care instruments. A functional adjustable paralysis movable shifter comprises a bottom frame, a fixing frame and two riding frames, the bottom of the bottom frame is fixedly connected with universal wheels with a braking function, and the fixing frame slides on the top of the bottom frame. The two riding frames are opened in a separated mode by unfastening the lock catch between the two riding frames and turning over the riding frames, then the shifter is moved to the bedside, a nurse firstly moves the legs of a patient to the device, and then the patient is slowly pulled up to be moved to a backrest for sitting. After the sitting frames are turned over, the two backrests are combined together, the two sitting frames are stably connected together under the action of the lock catches, daily living rehabilitation of the paralyzed patient is facilitated, the fixing frame is controlled by the lifting mechanism to conduct lifting adjustment on the top of the bottom frame, the sitting height of the patient is adjusted, and the patient can conveniently get in and out of the bed.
Owner:HEBEI LUOBEI PHARMACEUTICAL TECHNOLOGY CO LTD

Auxiliary traction apparatus for orthopedic surgeon

Disclosed in the present invention is an auxiliary traction apparatus for an orthopedic surgeon, relating to the technical field of orthopedics. The auxiliary traction apparatus comprises a bottom plate; an upper end of the bottom plate is rotatably connected to an inclined plate; an upper end of the inclined plate is rotatably connected to a sliding plate; the surface of the sliding plate is provided with a lower fixing ring and an upper fixing ring; a lower end of the sliding plate is connected to a slide plate; the slide plate is slidably connected to the bottom plate; the surface of the slide plate is rotatably connected to an electric push rod. In the present invention, the angles of the inclined plate and the sliding plate are changed by means of the electric push rod, so that the legs of a patient are lifted to help the patient move, thereby avoiding paralysis caused by the legs of the patient not moving for a long time; meanwhile, a connecting column and a spring can prevent the electric push rod from directly acting on the surface of the inclined plate, so that the operation can be stopped when the patient feels pain, thereby protecting the safety of the patient.
Owner:THE FOURTH AFFILIATED HOSPITAL OF GUANGZHOU MEDICAL UNIV(GUANGZHOU ZENGCHENG DISTRICT PEOPLES HOSPITAL)

Herbal solution containing Ruta Graveolens and Saxifraga, and method for its preparation

The present disclosure relates to a herbal mouthwash containing Ruta graveolens and Saxifraga, specifically developed for the prevention of neurological diseases such as Parkinson's, Alzheimer's, paralysis, and nerve damage. The process involves preparing the herbal mouthwash by soaking a finely ground mixture of Ruta graveolens and Saxifraga in alcohol. The resulting solution is administered as a mouthwash and used for rinsing and gargling. The invention offers an effective, natural therapeutic alternative for treating neurodegenerative diseases, promoting neuroprotection, and potentially supporting the regeneration of damaged nerve cells.
Owner:SCHILLING JOHANN GEORG

Position restraint device for neurosurgery nursing

The utility model discloses a neurosurgery nursing body position constraining device which comprises a bed board, a supporting frame is arranged at the bottom of the bed board, moving wheels are arranged at the four corners of the bottom of the supporting frame, fixing plates are arranged on the two sides of the end, located at the head, of the bed board, and connecting columns are rotationally connected to the fixing plates. An arm supporting plate is fixedly connected to the top end of the connecting column, two fixing belts are arranged on the arm supporting plate, and a movable seat is slidably connected to the portion, located on the lower half body, of the upper surface of the bed board. By unscrewing the first stud, the first knob can be separated from the bottom of the fixing plate, and the connecting column can be rotated, so that the arm supporting plate can rotate by taking the axis of the connecting column as the circle center, the arm placement of a patient can be adjusted, and the comfort of the patient can be improved; meanwhile, pain and paralysis caused by the fact that the handle of the patient is in the same state for a long time can be avoided.
Owner:JINHUA MUNICIPAL CENT HOSPITAL

clothespins

As we age, our bodies undergo changes, particularly numbness, pain, and paralysis in our hands, fingers, and arms, making it difficult to open standard metal spring clothespins with our fingers. This laundry peg, designed for those with limited strength, including the elderly, disabled, those with mild illnesses or injuries, and even infants, can easily open and close clothespins using their entire hands and fingers to clamp laundry. Instead of using standard metal springs, these clothespins feature a plastic arc section, a mating section, and a clamping section. The two clamping rods are molded as a single unit and fit together at the mating section. The top of the arc section is a spring, and by gripping both sides of the arc with your hands and fingers, you slide the interlocking rod to open and close the clamping section and clamp laundry. This laundry peg features a slip-resistant handle for those who want to hang out their laundry independently despite their limited strength. The top of the arc section is designed to prevent damage to the spring, making it suitable for general use. Since it does not use metal springs, it is easy to recycle and is an SDGs product.
Owner:狩野 三雄

Application of tranquilizing composition in preparation of medicine for preventing or treating Alzheimer disease

The invention belongs to the field of traditional Chinese medicine, and particularly relates to application of a tranquilizing composition in preparation of a medicine for preventing or treating Alzheimer's disease, the tranquilizing composition has a remarkable treatment effect on CL4176 nematodes, and has a remarkable inhibition effect on paralysis phenotypes caused by intramuscular A beta overexpression of the CL4176 nematodes. The nerve soothing composition can obviously delay the paralysis phenotype of the Alzheimer's disease caenorhabditis elegans, compared with a positive drug memantine hydrochloride, the paralysis inhibiting drug effect is obviously improved, and the nerve soothing composition has an obvious treatment effect on CL2355 nematodes, has an obvious recovery effect on chemotactic dysfunction of CL2355, has an obvious nerve protection effect, and can be used for treating the CL2355 nematodes. The medicinal value is higher.
Owner:QINGHAI UNIVERSITY

Treatment method for treating orthopedic difficult diseases based on acupuncture manipulation

PendingCN121129650AAcupunctureSpinal cord lesionHydrogen sulfide poisoning
The invention discloses a treatment method for treating orthopedic difficult diseases based on acupuncture manipulation, and belongs to the technical field of medical treatment. The method inherits traditional Chinese and western medicine theories and combines modern medicine, positioning diagnosis is carried out through chief complaint, inspection diagnosis, visual diagnosis and palpation, and high-end equipment such as CT and MRI is not needed. Acupuncture techniques such as one-finger meditation, pulling and stretching, needle stagnation, squeezing, smoothing, carrying and lifting, pinching and holding, shaking, pause pulling, rotating and the like are adopted, operation is flexibly adjusted according to the illness state, physique, age and gender of a patient without depending on medicine, injection and operation, and the principle that the inside is soft and the outside is rigid is followed. The traditional Chinese medicine composition can be used for treating difficult and complicated diseases such as vegetative humans caused by hydrogen sulfide poisoning, Green Barre syndrome, cervical and lumbar disc herniation related diseases, paralysis caused by cerebrovascular accidents or spinal cord injuries, joint deformity caused by copper poisoning, hysteria paralysis and the like, the curative effect is remarkable, for example, copper poisoning patients recover functions after 8 months, and hysteria paralysis patients can get out of bed after 7 days, and the traditional Chinese medicine composition is convenient to popularize.
Owner:张士禄

Emotional square cabin

The emotional square cabin belongs to an innovative idea in the field of artificial intelligence emotional accompanying, is used for immediate care of disabled old people, adjuvant therapy of cerebral palsy patients, family therapy of vegetative patients and emotional accompanying of disabled people with paralysis below cervical vertebra, and is suitable for emotional accompanying of different people such as infants, children, teenagers and adults. And the problems of emotion intelligence, social interaction and the like are solved for the personnel.
Owner:李一

A traditional Chinese medicine compound preparation for treating motor dysfunction of Parkinson's disease

This invention relates to the field of pharmaceutical technology for treating motor dysfunction in Parkinson's disease, and particularly to a traditional Chinese medicine preparation for treating motor dysfunction in Parkinson's disease. The formula consists of Cimicifuga rhizome, processed turtle shell, Angelica sinensis, raw licorice root, ginger-processed Pinellia ternata, Gastrodia elata, and scorpion. This invention uses a traditional Chinese medicine formula to treat motor dysfunction in Parkinson's disease. The medicinal materials comply with national regulations for the management of traditional Chinese medicine materials and have undergone clinical testing. The formula is rationally formulated with high synergistic effects and long-lasting and stable efficacy. Based on the principles of traditional Chinese medicine syndrome differentiation and treatment, this formula addresses the deficiency of both liver and kidney, and the insufficiency of qi and blood, with tremor and paralysis attributed to internal liver wind. It significantly improves motor dysfunction and tremor symptoms in Parkinson's disease. This preparation is highly effective, safe, reliable, and has few side effects. It can also significantly reduce the expression levels of tyrosine hydroxylase in the substantia nigra and striatum. This preparation represents a new approach to treating motor dysfunction in Parkinson's disease and has broad prospects in the field of treating this condition.
Owner:ZHEJIANG CHINESE MEDICAL UNIVERSITY

Position adjusting bolster for postoperative paralysis

The utility model relates to the technical field of body position pads, and discloses a body position adjusting bolster for postoperative paralysis, which comprises a bolster seat, the bolster seat is in a right triangle shape, the bottom of the bolster seat is horizontal, the included angle between the bolster seat and the horizontal plane is 30-40 degrees, the bolster seat is sequentially divided into a head cushion, a neck cushion and a body cushion from top to bottom, and a high semi-reclining position lying body surface is formed at the upper part of the bolster seat; a head groove is formed in the middle of the head cushion, a groove body is concave downwards in an arc shape, and a limiting protruding block is integrally connected to the portion, on one side of the edge of the head groove, of the head cushion; the upper surface of the neck pad protrudes out of the high semi-reclining position lying body surface, and an open arc-shaped neck groove is formed in the middle of the neck pad. By means of the head cushion, the neck cushion and the body cushion on the cushion seat, a patient can lie stably at a high semi-reclining position when the head tilts laterally, the lying comfort level is improved, throat secretions can be prevented from entering an airway to cause suffocation, the anxiety degree of the patient can be reduced, the comfort level is improved, and the inclined upward posture of the patient at the high semi-reclining position can be matched with a nurse for treatment more easily. Therefore, the satisfaction degree of family members is improved.
Owner:THE FIRST AFFILIATED HOSPITAL OF GUANGXI MEDICAL UNIVERSITY

Rehabilitation training device

The invention provides a rehabilitation training device which comprises a back plate, a fixing belt, a support and a table top, the fixing belt is arranged on the back plate, the fixing belt is adjusted within a certain range according to the size of a human trunk and fixes the human trunk to the back plate, the back plate is detachably installed on the support or the table top, and the table top has a certain supporting area in the horizontal direction. The table top is installed on the support, the support is provided with a transverse rod extending in the horizontal direction, the transverse rod is close to the ground and can be inserted below the bed, and a fulcrum is arranged below the end of the transverse rod so that the fulcrum of the support can be away from the gravity center of the support. For a critical patient who lies in bed for a long time or is weak, the rehabilitation training device can be used for achieving sitting and simple rehabilitation training more conveniently, medical staff can transfer the patient more conveniently, participation of multiple medical staff is not needed, turning around is not needed compared with a wheelchair, the transferring difficulty is reduced, and the medical staff can carry out rehabilitation training more conveniently. And for patients with limited activities or paralyzed patients, the device is relatively practical.
Owner:THE FIRST AFFILIATED HOSPITAL ZHEJIANG UNIV COLLEGE OF MEDICINE

HERV-k (HML-2) ENV analog fusion proteins for antigen specific immunotherapy and methods of use

PCT designated stageWO2026030592A1Antibody mimetics/scaffoldsViral antigen ingredientsDiseaseMuscular weakness
The present disclosure provides recombinantly manufactured fusion proteins comprising a HERV-K (HML-2) Env protein fragment or an analog thereof linked to a human Fc fragment. Embodiments include the administration of the fusion proteins to patients having a disease or a disorder with the intention of mitigating and / or reducing the duration of symptoms associated with the condition or disease (for example but not limited to muscular weakness, paralysis and respiratory failure), and / or preventing symptoms associated with the condition or disease, for example, by preventing motor neuron degeneration and cell death in ALS patients associated with the condition or disease. Accordingly, "treatment" generally means both therapeutic treatment and prophylactic or preventative measures. Improvement after treatment may be manifested as a decrease or elimination of such symptoms, e.g., by a decrease or elimination of symptoms associated with ALS, and / or by a decrease in the duration of such symptoms.
Owner:TWILIGHT BIOSCIENCE INC