5 results about "Sulfasalazine" patented technology

The utility model discloses a sulfasalazine synthetic equipment with stirring mixing mechanism relates to sulfasalazine synthetic field, including mixing jar body, break mechanism, break mechanism installs in mixing jar body top one side, lead screw, the lead screw, rotation is connected between mixing jar body inside top and bottom, wherein, the sliding sleeve is cooperated with the outside screw thread of lead screw, the connecting rod is fixed with the outside of sliding sleeve, the annular scraper is fixedly connected with connecting rod end, the annular scraper outside is attached to mixing jar body inner wall, break mechanism includes the discharge bin, the feed inlet is seted up in the middle of discharge bin top, and the device is pretreated to raw material through break mechanism, when the rotating shaft rotates, the mutual meshing of grinding teeth can carry out extrusion, shearing effect to raw material, realize the purpose of breaking, can make the powder that is relatively coarse become finer through the effect of grinding simultaneously.

The utility model discloses a kind of sulfasalazine fluidized bed with dust removal mechanism, it is related to fluidized bed technical field, including fluidized bed body, the side of fluidized bed body is connected with air inlet tank;The inside of the air inlet tank is slidably provided with filter screen, the inside of the air inlet tank is provided with fan, and fan is located at the side of filter screen close to fluidized bed body, the side of filter screen away from fluidized bed body is provided with rotating bar;When fan switches direction and backblows filter screen, rotating bar is driven to rotate by transmission assembly, impurities on filter screen are knocked loose, the side of filter screen close to fluidized bed body is provided with elastic component;The sulfasalazine fluidized bed with dust removal mechanism, by setting fan, rotating bar and transmission assembly and other structures, backblowing filter screen, realize the cleaning of impurities, while rotating bar hits filter screen, so that impurities are loose, ensure dust removal effect, improve the use efficiency of sulfasalazine fluidized bed.

The application relates to the medical technical field, in particular to application of sulfasalazine in preparation of a medicine for treating primary biliary cholangitis (PBC) which is poorly responsive to ursodeoxycholic acid (UDCA), aiming at the clinical problem that about 40% of PBC patients are poorly responsive to the first-line drug UDCA, have high disease progression risk and limited second-line treatment options, and providing a new treatment use of the mature drug sulfasalazine. Through prospective clinical research, it is confirmed that, on the basis of UDCA standard treatment, combined use of sulfasalazine (1.5g / day, a treatment course of 48 weeks) can significantly improve liver biochemical indexes of UDCA non-responders, including alkaline phosphatase and gamma-glutamyltransferase, and 62.5% of the patients reach composite biochemical response. The application provides a new, effective, safe and highly accessible second-line treatment strategy for PBC patients who are poorly responsive to UDCA, and has a good clinical application prospect.

This utility model discloses an energy-saving sulfasalazine wastewater treatment device, relating to the field of wastewater treatment equipment. It includes a first treatment tank and a second treatment tank, which are vertically arranged. An upper collection tank and a lower collection tank are respectively connected vertically inside the first and second treatment tanks, and are connected by a connecting rope and pulley. The lower collection tank is heavier than the upper collection tank. Both the upper and lower collection tanks have filter screens at their bottom ends. After the sediment in the wastewater settles, the wastewater is discharged from the first treatment tank and flows into the second treatment tank. The downward discharge of wastewater causes the collection tank to descend, thereby pulling the upper collection tank upward. This causes the collection tank to lift the sediment in the wastewater, facilitating subsequent processing. The wastewater utilizes gravity to treat the sediment, requiring no additional energy, making it environmentally friendly and energy-saving.