113 results about "Joint damage" patented technology

A movement augmentation system that provides various forms of feedback, including real-time and post-performance for training and rehabilitation is disclosed. The systems, devices and methods provide augmentation to human movement behavior in order to accelerate acquisition of complex movement skills by a user and to mitigate injuries from poor movement technique (e.g., joint damage or muscle fatigue). An environment is provided that enables systematic and comprehensive capabilities through integration of its components.

A non-invasive system and method are provided for determining the presence or absence of neural, muscular, soft tissue, bone or joint damage or other disease affecting a person's hand. A preferred system includes a plurality of digit contact members, one of which is engageable by the person's thumb and others which are engageable by other digits of the hand, at least one of the other digits being innervated by the ulnar nerve. Force detectors are operatively connected to at least two of the digit contact members for measuring the quantity of force applied to the respective digit contact members by at least one digit innervated by the median nerve and a digit innervated by the ulnar nerve, as they engage in a natural gripping motion. The measured forces may be used to calculate quality indices useful in the diagnosis of disease and the monitoring of progression of disease.

The invention discloses a beam structure damage identification method based on modal flexibility curvature matrix norms. The beam structure damage identification method includes the steps of conducting modal testing to obtain modal flexibility matrixes before and after beam structure damage respectively; acquiring curvatures of the flexibility matrixes before and after beam structure damage, sequentially acquiring the norms of column vectors of flexibility curvature matrixes and utilizing norm differences to position structure damage; computing a beam structure joint damage degree according to relative change of the flexibility curvature matrix norms so as to obtain a unit damage degree through computation. The beam structure damage identification method is capable of positioning single-damage and multi-damage working conditions of a beam structure effectively and capable of identifying the damage degree precisely, well overcomes the defect that existing modal flexibility curvature indexes cannot be used for damage degree identification, and can be applied to nondestructive testing and damage degree evaluation of the beam structure.

A method, machine-readable storage medium embodying computer-readable code and automated system for assaying or monitoring the extent of joint or bone deformity reported by a summarized score that may include joint space narrowing, bone erosion and periarticular osteoporosis in a joint-degenerative or joint-damaging disease in a subject are disclosed. From a digitized image of one of the subject's straight bone terminated with a joint such as fingers, coordinates of right and left bone contours of a selected middle or proximal phalange are determined, and these coordinates are in turn used to determine the coordinates of a minimum width in the middle region of the phalange and one or more apices in a region adjacent at least one side of a joint of the selected phalange. These latter coordinates are used in selecting a reference joint contour representing normal-bone contour for that phalange, or the contour of the patient phalange from an earlier x-ray image. Guided by the reference joint contour, a region of the selected joint of the patient is analyzed to assay or monitor the extent of joint or bone deformity in the subject.

Methods of treating joint damage in a subject eligible for treatment are provided involving administering an antagonist that binds to a B-cell surface marker, such as CD20 antibody, to the subject in an amount effective to slow progression of the joint damage as measured by radiography. Further provided are articles of manufacture useful for such methods.

A method scores a sample, by receiving a first dataset associated with a first sample obtained from a first subject, wherein said first dataset comprises quantitative data for at least two markers selected from the group consisting of: CCL22; CHI3L1; COMP; CRP; CSF1; CXCL10; EGF; ICAM1; ICAM3; ICTP; IL1B; IL2RA; IL6; IL6R; IL8; LEP; MMP1; MMP3; PYD; RETN; SAA1; THBD; TIMP1; TNFRSF11B; TNFRSF1A; TNFSF11; VCAM1; and VEGFA; and determining a first SDI score from said first dataset using an interpretation function, wherein the first SDI score provides a quantitative measure of the rate of change in joint structural damage in said first subject.

The present invention relates to methods for preventing the progression of joint damage in a subject having hyper-uricemia and who has gout thereof by administering a therapeutically effective amount of at least one xanthine oxidoreductase inhibiting compound or salt thereof. Moreover, the present invention also relates to methods of preventing joint damage in a subject having hyperuricemia and who has gout by administering a therapeutically effective amount of at least one xanthine oxidoreductase inhibiting compound or salt thereof.

The present invention provides methods and compositions for treating blood clotting factor disorders and/or reducing bleeding-associated joint damage by treatments delivered to the joint in a subject.

The invention relates to the technical field of nursing and rehabilitation, and provides a wearable device for monitoring knee joint movement information, which comprises a joint bracket, an acquisition module, a data processing device and a power supply. The data processing device comprises a signal processing unit, a data storage unit and an information prompt unit. When the joint bracket is worn at the knee joint, the acquisition module is used for collecting the signals of the motion information of the knee joint in real time, and transmitting the related signals of the motion informationto the signal processing unit, and the signal processing unit processes the signals of the motion information, storing the processed data in the data storage unit. Once the numerical data corresponding to the signals of the motion information exceeds the preset standard data, the signal prompt unit informs the user of the current knee joint motion condition through the prompt tone and the like, thereby providing reasonable motion advice or the risk warning of a joint damage. The whole device is convenient to wear and has high portability.

The invention relates to medical compress patches, in particular to a medical far infrared hot compress patch for soft tissue repairing and a preparation method thereof. The medical far infrared hot compress patch comprises a non-woven fabric bag, a heating layer arranged at the non-woven fabric bag, and a pressure sensitive adhesive tape used for fixing the non-woven fabric bag; the heating layer is composed of 35-45% of reduced iron powder, 0.1-5% of aluminum powder, 5-15% of far infrared ceramic powder, 10-16% of active carbon, 0.5-2% of polymer water-absorbent resin, 1-6% of sodium chloride and rest of purified water by weight. By means of a thermal therapy and infrared therapy combination mode, the medical far infrared hot compress patch for the soft tissue repairing has physical therapy and therapy effects for the inflammation and indisposition due to rheumatic arthritis, cervical spondylosis, lumbar muscle degeneration, lumbar disc herniation, scapulohumeral periarthritis, soft tissue injury, hyperosteogeny, ischialgia, pain from rheumatism, knee injury, chronic prostatitis, chronic mastitis, hyperplasia of mammary glands, chronic gastroenteritis, chronic gynaecology inflammation, cold in uterus, stomach cold, pain from rheumatism and the like.

The invention relates to a novel composite maintaining method of a hinged joint damage of a bridge. The method is characterized in that (1) a broken asphalt layer and cement paved layer on both sides of a hinged joint of a bridge to be maintained are chipped away, the broken concrete in a plate-girder chamfer is chipped away; (2) plastic foam and adhesive tapes are used for sealing the gaps at the bottom of the plate-girder chamfer; (3) a foldable reinforcement cage is arranged in the chamfer at the plate-girder hinged joint; (4) reinforcing steel bars on the upper part of the foldable reinforcement cage, reinforcing steel bars laid on the previous bridge deck and added reinforced nets are in electric soldering connection; (5) quick concrete is cast at the chamfer of the plate-girder hinged joint and the paved layer of the bridge deck; (6) the quick concrete is maintained; and (7) elastic concrete is paved and compacted on the quick concrete after the quick concrete reaches a specific strength, and the pavement can be opened. The maintaining method has the advantages that the structure problem is solved, the bridge decks are connected into a whole and integrally stressed, the maintenance is quick, and the traffic is little influenced.

The invention discloses a roof daylighting plate joint connecting plate which comprises a daylighting plate. The roof daylighting plate joint connecting plate is characterized in that a connecting backplate is arranged at the bottom of the daylighting plate, screws are arranged on the connecting backplate and penetrates the daylighting plate, a pressing strip is arranged on the daylighting plate, holes corresponding to the screws are formed in the pressing strip, and bolts are arranged on the pressing strip and fixedly connected with the screws. Through the HV470 color steel roof daylighting plate connecting plate, the problem of joint damage generated by thermal expansion and cold contraction of an overlapping position between a roof color steel plate and the daylighting plate can be solved effectively. A connecting mode in a clamp form is adopted, so that the roof color steel plate and the polyester daylighting plate are connected more closely, and the waterproof effect is improved substantially.

The invention discloses an assembling type sectional precast concrete hollow plate girder structure and a manufacturing method thereof. The assembling type sectional precast concrete hollow plate girder structure comprises top plates and U girders, which are connected to formed a plate girder structure, wherein the top plates and the U girders are made through casting concrete and are respectively formed by splicing a plurality of sections in the longitudinal direction; shear keys are arranged on the outer surfaces and the longitudinal cross sections of webs of the U girders and on the longitudinal cross section of the top plates in a matching and precast manner; the plate girder structure is provided with longitudinal pre-stressed tendons and horizontal pre-stressed tendons, and epoxy resins are applied to interfaces of spliced seams. Compared with a conventional plate girder structure, the plate girder structure disclosed by the invention has the advantages that hinged joint damage is avoided, the bridge completeness of the hollow plate girders is improved, longitudinal cracks generated in bottom plates are avoided, transportation and hoisting are facilitated, the coming off of inner molds of the hollow plate girders are facilitated through U-shaped section, the strength of seams is improved, the cast-in-situ construction quantity is small, mechanized effect is facilitated, influence on environment and ground traffic is small, construction cost is reduced, and the construction period is shortened.

A puncture inside-expanding type connector belongs to the connecting technical field of stranded wires. The invention is characterized in that the stranded wire is loosely inserted in a hole of the connector formed by surrounding walls. The surrounding walls are provided with at least one hole or one hole with threads. A steel nail passing through the hole or a screw passing through the hole with threads are deeply berried in the stranded wire in the hole of the connector. The connector can be provided with a carrier at one end, and the other end is used for connecting the single head connector of the stranded wire; or two ends are all used for connecting the double-head connector of the twisted line. To implementing the invention has the positive effects of no joint damage, simple structure and operation. As the screw is screwed in the stranded wire to lead the stranded wire to expand to the surrounding walls to form a body with a sleeve pipe, the invention can provide powerful contacting force and is applied to the connection of a wire rope as well as to the connection between two cable stranded wire conductors or used for the connection on the end of a stranded wire conductor. The invention is a very practical and feasible invention with a board application range.

The invention provides a finite element simulation method for determining a complete rule of solder joint damage accumulation under an irregular temperature-following profile. The method comprises thefollowing steps: S1, a finite element simulation pretreatment; S2, finite element simulation of solder joints under different temperature loads, S3, finite element simulation post-processing, S4, determination of the nonlinear damage accumulation expression of solder joints under irregular temperature profile. The nonlinear damage accumulation rule determined by the simulation method is based ona fatigue crack damage model of a solder joint, Compared with the traditional method based on statistics, this method is more practical and takes into account the influence of stacking sequence of different temperature profiles. The result is more accurate, and the error can be controlled within 8%, which greatly reduces the error range.

The invention relates to a wood structure fabricated type profile steel bolt joint, and belongs to the field of civil and architectural engineering. The wood structure fabricated type profile steel bolt joint comprises a first wood member (1) and a second wood member (2) which are connected with each other, a first in-fill steel plate (4) is embedded in the second wood member (2), the first in-fill steel plate (4) penetrates through the first wood member (1), and the wood structure fabricated type profile steel bolt joint further comprises a first side surface steel plate (6) wrapped with thelower surface of wood of a second wood member (2) joint area. Compared with the prior art, the first in-fill steel plate and a second in-fill steel plate can be installed separately, the constructionis convenient, simple and effective, meanwhile, the first side surface steel plate and a second side surface steel plate can obviously improve the tension capacity of the second wood member in the cross grain direction, joint damage is avoided, and the stability of the joint is improved and the service life of the joint is prolonged.

The present invention refers to the treatment of a patient suffering from rheumatoid arthritis by showing a reduction in signs and symptoms, a major or complete clinical response (remission) or even prevention of structural damages to the joints by administering a delayed-release dosage form of a glucocorticoid to a subject in need thereof.

Disclosed is an anti-collapse security evaluation method for a self-support communication tower. By adoption of the anti-collapse security evaluation method, dynamic response of the self-support communication tower in a complete tower collapse process when key members are damaged under a wind load effect can be accurately simulated; the anti-collapse security of the self-support communication tower can be evaluated; by combination of conventional design software and universal finite element software, modeling of the communication tower with a large number of members can be rapidly and conveniently completed while simulation of a complex dynamic collapse complete process also can be realized; and by considering various adverse wind directions, and working conditions of damage of single members and joint damage of multiple members, the analysis result is detailed and reliable. The evaluation method disclosed by the invention is simple in analysis thought, easy to learn and master, can be used for designing a newly built tower as well as for evaluation of a net tower, so that the method can be widely popularized among tower designers, and the blank of the self-support communication tower in anti-collapse research and design is filled up.

The invention relates to a medical patch, and specifically relates to a medical magnetic therapy type hot compressing patch for treating soft tissue pain and a preparation method thereof. The medical magnetic therapy type hot compressing patch comprises a nonwoven fabric bag, a heating magnetic therapy layer arranged at the nonwoven fabric layer, and a pressure sensitive adhesive belt for fixing the nonwoven fabric bag, wherein the heating magnetic therapy layer is prepared from the following raw materials in percentage by weight: 35 to 45% of iron powder reduced, 8 to 12% of permanent magnetic powder,10 to 16% of activated carbon, 0.5 to 2% of super absorbent polymer, 1 to 6% of sodium chloride, and the balance of purified water. According to the medical magnetic therapy type hot compressing patch, the thermal therapy and the magnetic therapy are combined; the medical magnetic therapy type hot compressing patch has the physiotherapy and treatment effects for inflammations and pain caused by rheumatic arthritis, pain in waist and lower extremities, cervical spondylosis, lumbar disc herniation, scapulohumeral periarthritis, soft tissue injury, osteoproliferation, sciatica, pain from rheumatism, knee joint injury, chronic prostatitis, chronic mastitis, hyperplasia of mammary glands, chronic pelvic inflammatory disease, chronic gastroenteritis, chronic gynaecology inflammation, cold in uterus, stomach cold and pain from rheumatism.

A procedure for regenerating cartilage in a patient's joint damaged by Osteoarthritis by transplanting autologous hematopoetic stem cells extracted from a human, preferably the same human. The procedure begins by screening to ensure that the patient is a suitable candidate, then preparation of the patient for the stem cell transplantation by a combined regimen of intra-articular injection to diminish inflammation and facilitate apoptotic cell clearance, plus subcutaneous injection of hematopoetic growth factor. The autologous hematopoetic stem cells are then purified by incubating a blood sample with magnetic polystyrene beads (Dynabeads™) coated with a monoclonal antibody specific for CD34 cell membrane antigen. The stem cells are separated from the blood sample using a magnetic particle separator, and washed through a plurality of washing substeps. The purified and separated stem cells are suspended in a particular transplant solution, and the transplant solution is injected into the patient's joint such that the purified and separated autologous hemotopoetic stem cells enter the patient's damaged joint, and regenerates. The transplant solution contains specific growth factors that direct the stem cells into the areas of damaged or absent cartilage, allowing the stem cells to differentiate into young chondrocytes. This produces new healthy cartilage with a high potential in restoring the integrity and functionality of the joint.

A nutritional product for protecting bones and joints, characterized in that the nutritional product is a composition, and the raw materials of the composition include the following components according to the weight ratio: 1-100 parts of astaxanthin, 1-5000 parts of collagen, vitamin C1 ~200 parts, DHA1~100 parts, EPA1~100 parts. The invention discloses a nutritional product that can delay cell aging, improve muscle endurance, inhibit joint inflammation, increase the strength of joint soft tissue, improve the secretion of synovial fluid, protect joint tissue and repair joint damage. It has a good healing effect on joint inflammation and promotes the recovery of joint ligaments. Long-term use can protect joint tissue, inhibit inflammation, promote the repair of joint damage, and improve muscle endurance.