65 results about "Scrophularia" patented technology

The invention discloses a Chinese medicine preparation for treating pulmonary nodules and a preparation method thereof, and relates to the technical field of medicines for treating respiratory diseases. Compared with the prior art, the Chinese medicine preparation for treating pulmonary nodules prepared by the invention is treated from five aspects, including tonifying the lung and replenishing qi, resolving phlegm and eliminating phlegm, softening and dispersing nodules, clearing away heat and detoxifying, and eliminating carbuncle and dispersing nodules, by combining selected medicinal materials of Codonopsis pilosula, Astragalus membranaceus, Chinese yam, Schisandra chinensis, Rehmannia glutinosa, Morus alba, Salvia miltiorrhiza, Curcuma zedoaria, Concha oyster, Scrophularia ningpoensis, Rhizoma Anemarrhenae, Scutellaria barbata, and Beehive. It is aimed at treating both the symptoms and the root cause of pulmonary nodules caused by lung deficiency, phlegm, dampness and blood stasis coagulation in the lungs, and is convenient to take, and can effectively control and reduce pulmonary nodules. The preparation of the Chinese medicine preparation of the invention optimizes the heat transfer and mass transfer in the decoction process by physically adding a carrier during the decoction process, changes the osmotic pressure difference at the interface of the medicine liquid, etc., accelerates the dissolution and diffusion of the effective ingredients, is easier to extract and prepare, has a shorter decoction time, and is more efficient.

The invention discloses a traditional Chinese medicine composition for treating pulmonary nodule as well as a preparation, a preparation method and application thereof. The traditional Chinese medicine composition comprises the following traditional Chinese medicine raw materials in parts by weight: 30-45 parts of oyster, 15-30 parts of selfheal, 10-15 parts of radix scrophulariae, 10-15 parts of thunberg fritillary bulb, 10-15 parts of dandelion, 10-15 parts of curcuma zedoary and 5-10 parts of pseudobulbus cremastrae seu pleiones. The traditional Chinese medicine composition for treating the phlegm-heat stagnation type pulmonary nodules has the effects of clearing heat, eliminating phlegm, removing blood stasis and eliminating stagnation, is obvious in clinical effect, has a reliable empirical basis, and is expected in economic and social benefits.

The application belongs to the technical field of traditional Chinese medicines, and discloses a traditional Chinese medicine composition for treating abdominal distension and diarrhea of cold-heat complex type and a preparation method thereof. The technical scheme points of the traditional Chinese medicine composition are as follows: the traditional Chinese medicine composition is composed of the following raw medicinal materials in parts by weight: 3-6 parts of perilla, 3-10 parts of dried ginger, 3-12 parts of eucommia, 3-10 parts of scrophularia, 2-6 parts of coptis, 10-20 parts of fried coix seed, 6-10 parts of clear pinellia, 3-10 parts of dried tangerine or orange peel, 10-15 parts of poria, 6-10 parts of wheat-cooked atractylodes, 6-10 parts of vinegar-cured corydalis, 6-10 parts of vinegar-cured bupleurum, 6-10 parts of pericarpium zephyritae, 6-10 parts of chuanxiong, 6-10 parts of magnolia officinalis, 6-10 parts of fried hawthorn fruit, 3-6 parts of platycodon, and 3-10 parts of fried licorice. The traditional Chinese medicine composition and the traditional Chinese medicine water pill prepared from the traditional Chinese medicine composition have the effect of treating abdominal distension and diarrhea of cold-heat complex type.

The invention provides a preparation method and application of CTMAB modified scrophularia ningpoensis root biological activated carbon. The preparation method comprises the following steps: firstly, pre-treating radix scrophulariae root dregs, then soaking with a NaOH solution, sintering at high temperature to obtain NaOH modified radix scrophulariae root biological activated carbon, and modifying with hexadecyl trimethyl ammonium bromide to obtain the CTMAB modified radix scrophulariae root biological activated carbon. The CTMAB modified scrophularia ningpoensis root biological activated carbon disclosed by the invention has the characteristics of large specific surface area, developed pore structure, multiple oxygen-containing functional groups and strong stability and dispersity, can be used for adsorbing dye wastewater, and has stable reusability. The invention not only solves the problem of treatment of scrophularia ningpoensis root residue waste, but also obtains an excellent adsorption material, and shows good application prospects in the fields of dye wastewater treatment and water purification.

This invention belongs to the field of pharmaceutical technology, specifically relating to the application of a traditional Chinese medicine composition in the preparation of drugs for improving cognitive impairment. By weight, the traditional Chinese medicine composition comprises: 225-300 parts rhubarb, 50-75 parts pig bile powder, 90-120 parts aster, 360-480 parts scrophularia, 180-240 parts immature bitter orange peel, and 180-240 parts areca nut. This invention is the first to demonstrate that a composition of six traditional Chinese medicines, including scrophularia, rhubarb, and areca nut, significantly improves memory acquisition (induced by scopolamine), consolidation (induced by sodium nitrite), and retrieval impairments, covering the entire process of memory formation, encoding, storage, and retrieval, thus overcoming the limitations of existing drugs that only target a single memory stage.

The present invention discloses a traditional Chinese medicine composition for treating post-infectious cough, as well as its preparation, preparation method, and application, belonging to the field of post-infectious cough medicine. The traditional Chinese medicine composition for treating post-infectious cough proposed by the present invention comprises the following raw materials: mulberry leaf, roasted ephedra, golden fecundation, honey white qian, perilla seed, loquat leaf, burdock fruit, thunbergia bulb, scrophularia, bombyx batryticatus, platycodon grandiflorum, and roasted liquorice root, with a mass ratio of 5-15:6-10:5-15:5-15:5-15:5-15:5-15:5-15:5-15:5-15:5-15:3-9. The traditional Chinese medicine composition proposed by the present invention highly conforms to the pathogenesis of PIC, which is "wind evil invading the lungs, lung obstruction and qi reversal." It is a clinically effective prescription for treating chronic and subacute coughs such as PIC. It has good therapeutic effects on both wind-cold cough and wind-heat cough, cough with or without phlegm, and can effectively reduce cough severity and cough sensitivity.

This invention belongs to the field of traditional Chinese medicine detection technology, specifically relating to a multi-component thin-layer chromatography (TLC) identification method for pediatric runtong syrup. This invention establishes specific TLC identification processes for roasted radish seed, immature bitter orange, hemp seed, and scrophularia root, optimizing the sample pretreatment, developing solvent ratio, spotting volume, and colorimetric inspection conditions for each component. After specificity and robustness studies, the method demonstrates good stability under varying temperature, humidity, TLC plate type, and spotting volume ranges, exhibiting no negative interference and clear spots, enabling accurate multi-component identification. This invention is the first to establish a TLC identification method for these four medicinal materials in pediatric runtong syrup, providing a scientific and reliable technical means for the quality control of this compound preparation and filling a gap in existing technology.

The invention belongs to the field of quality analysis of traditional Chinese medicines, and particularly discloses a method for determining the content of iridoid components, which adopts HPLC (High Performance Liquid Chromatography) to simultaneously determine the contents of six iridoid components, namely morroniside, geniposide, loganin, picroside II, picroside I and harpagoside, in four medicinal materials, namely dogwood, cape jasmine, picrorhiza scrophularia and radix scrophulariae. According to the method, the content of iridoid components in multiple medicinal materials can be measured, the detection cost is reduced, the detection time is shortened, and the detection efficiency is improved. The detection method provided by the invention is stable and reliable, has the advantages of strong specificity, good reproducibility and the like, can ensure the safety and effectiveness of clinical medication of common medicinal materials such as dogwood, cape jasmine, rhizoma picrorhizae, radix scrophulariae and the like, and better meets the medical and market requirements.

1. Name of this design product: Warming Patches (Scrophularia and Kidney). 2. Purpose of this design: a heat patch for use on the human body or clothing by means of pasting, binding, etc. 3. The key design features of this product are the combination of shape and pattern. 4. The picture or photo that best illustrates the key design points: Design 1 front view. 5. Design 1 is designated as the basic design. 6. Other matters requiring explanation: This application is for a thin product, so the left and right tilt views are omitted.

The invention belongs to the technical field of traditional Chinese medicines, and mainly relates to a traditional Chinese medicine composition for clearing heat from throat, a traditional Chinese medicine preparation and a preparation method and application thereof. The traditional Chinese medicine composition is prepared from the following traditional Chinese medicines in parts by weight: 0.9 to 1.5 parts by weight of radix scrophulariae, 1.2 to 5.0 parts by weight of radix polygonati officinalis, 1.0 to 3.0 parts by weight of radix glehniae, 1.0 to 1.5 parts by weight of radix rehmanniae, 1.0 to 3.0 parts by weight of radix ophiopogonis, 1.5 to 6.0 parts by weight of gypsum and 0.5 to 3.0 parts by weight of liquorice root. The preparation method of the traditional Chinese medicine preparation comprises the working procedures of processing, burdening, extracting, concentrating, preparing a soft material, granulating, drying and finishing granules. The traditional Chinese medicine composition or the traditional Chinese medicine preparation for clearing heat from throat can relieve symptoms such as red and swollen pharynx, dry mouth and dry throat, pharyngalgia, pharynx itching, scorching fever, less phlegm and foreign body sensation of pharynx caused by heat evil, and has a remarkable curative effect on chronic pharyngitis. Through a unified preparation method, the accuracy of the quality and dosage of the used medicinal materials and the stability of the treatment effect are ensured.

The invention relates to the field of utilization of Chinese herbal medicine radix scrophulariae, and discloses a preparation method of a radix scrophulariae extract, which comprises the following steps: S1, taking dried radix scrophulariae as a raw material, crushing and sieving; s2, adding 85-95% ethanol solution according to the proportion of 3 times of the mass of the radix scrophulariae; s3, extracting for 3 times under a reflux condition, and extracting for 4 hours each time; s4, combining the extracting solutions, and recovering the solvent to obtain a radix scrophulariae extract; the dried radix scrophulariae roots in the step S1 are fine powder passing through a 100-mesh sieve; the temperature of reflux extraction in the step S3 is 75-90 DEG C; the extracting solution subjected to reflux extraction in the step S3 is subjected to vacuum concentration. It is found through tests that 2-4 [mu] g / mL of the radix scrophulariae extract can significantly inhibit LPS-induced Caco2 cell inflammation and is non-toxic to cells, and soybean saponin-induced zebra fish food-borne enteritis is reduced, including the transcriptional level of proinflammatory factors I < L1beta > and I < L8 > in intestinal tracts.

The present application belongs to the technical field of traditional Chinese medicine, and relates to a traditional Chinese medicine composition for treating subacute thyroiditis, which comprises the following traditional Chinese medicine raw materials in a mass ratio: Bupleurum 9-12 parts; Red Peony Root 10-15 parts; Indigowood Leaf 10-15 parts; Scrophularia 9-12 parts; Glechoma 10-15 parts; Limnophila 15-30 parts; Millettia 3-6 parts; Omphalopsis 6-9 parts; and Aquilaria 10-15 parts. The present application also provides a traditional Chinese medicine preparation for treating subacute thyroiditis: the above traditional Chinese medicine raw materials are taken according to the ratio, and a pharmaceutically acceptable carrier is added to form a traditional Chinese medicine preparation, wherein the traditional Chinese medicine preparation comprises an ointment and an external use patch. The traditional Chinese medicine composition and the traditional Chinese medicine preparation for treating subacute thyroiditis have the advantages of being simple and easy to use, rapid in effect, and green and safe.

The invention belongs to the technical field of chemical drugs, and particularly relates to application of a traditional Chinese medicine composition in preparation of drugs for treating recurrent clostridium difficile infection.The traditional Chinese medicine composition is prepared from 10-50 g of fresh ginger, 3-20 g of honey-fried licorice roots, 5-30 g of ginseng, 3-20 g of dried ginger, 3-30 g of scutellaria baicalensis, 3-30 g of pinellia ternate, 3-15 g of coptis chinensis and 10-30 g of Chinese dates. The traditional Chinese medicine composition is excellent in clinical effect, and in sample research on high-risk crowds such as old people and immunosuppression CDI relapse patients, the treatment scheme of the vancomycin combined with the ginger heart-fire purging decoction is remarkably superior to vancomycin single-drug treatment in the aspect of continuous clinical response rate at the main curative effect end point. This benefit is achieved mainly by reducing the recurrence rate of CDI by more than 60%. The combined scheme shows a robust curative effect in key subgroups such as the elderly and immunosuppressive subgroups, is good in safety, does not increase extra adverse event risks, and particularly does not observe renal function impairment.

The invention belongs to the technical field of Chinese medicine preparations, and in particular to a kind of Chinese medicine oral liquid for preventing and controlling blue ear disease of pigs and its preparation method. The present invention adopts ethanol percolation extraction after pulverizing rhubarb, coptis root, peppermint, bupleurum and schizonepeta to obtain extract A, scutellaria baicalensis, arctium lappa, dried tangerine peel, forsythia suspensa, cimicifuga heracleifolia, platycodon grandiflorum, liquorice, puffball, figwort, isatis root, indigo naturalis, talcum powder and percolation extraction medicine residues are subjected to water extraction and then reflux extraction of volatile oil, extract B and distillate are obtained, and then extract B is subjected to secondary alcohol precipitation and then N-methyl pyrrolidone and extract A and distillate are added, sodium benzoate and water are added, pH value is adjusted, and final product is obtained. In the Chinese medicine oral liquid for preventing and controlling blue ear disease provided by the present invention, effective ingredient content is high, stability is high and good, can effectively resist PRRSV virus, treat blue ear disease of pigs.

The invention discloses a traditional Chinese medicine composition for treating chemotherapy-related oral mucositis and a preparation method and application thereof. The traditional Chinese medicine composition is prepared from the following raw material medicines in parts by weight: 6-12 parts of radix rehmanniae recen, 6-12 parts of radix ophiopogonis, 6-12 parts of radix scrophulariae, 6-12 parts of honeysuckle, 6-12 parts of fructus forsythiae, 3-7 parts of radix scutellariae, 1-3 parts of lotus plumule, 3-7 parts of mint and 3-7 parts of borneol. The composition has the effects of nourishing yin, clearing heat, astringing sores and promoting tissue regeneration, and clinical tests prove that the composition can remarkably reduce the occurrence rate of chemotherapy-related oral mucositis of hematological malignancy patients, relieve the damage degree of oral mucosa, shorten the lasting time of ulcer and pain and effectively improve clinical symptoms of traditional Chinese medicine, and is high in safety.

This invention belongs to the field of traditional Chinese medicine technology, specifically relating to a herbal antibacterial hydrogel for ulcer healing, its preparation method, and its application. The hydrogel is composed of a herbal composition and a matrix. The herbal composition includes dandelion, angelica, scrophularia, forsythia, phellodendron, atractylodes, angelica dahurica, and raw licorice. The matrix contains chitosan, polyvinyl alcohol, water, and glacial acetic acid. The effective components of the herbal medicine are extracted by decoction, concentrated, and freeze-dried to obtain a freeze-dried powder. This powder is then mixed with a chitosan aqueous solution and cross-linked using a liquid nitrogen cyclic freezing method to form the hydrogel. This invention closely addresses the core pathogenesis of diabetic foot ulcers—"blood stasis, dampness, and heat (toxin)"—allowing the various herbs to synergistically exert their effects of clearing heat and detoxifying, promoting blood circulation and removing blood stasis, drying dampness and astringing sores, and nourishing blood and promoting tissue regeneration. The chitosan matrix endows the hydrogel with good biocompatibility, antibacterial properties, and sustained-release drug properties, which can improve the microenvironment of the ulcer wound, inhibit inflammatory responses, and promote granulation tissue growth, effectively promoting the healing of skin sores such as diabetic foot ulcers, and has broad application prospects.

The invention belongs to the field of biological medicine, and particularly relates to a traditional Chinese medicine composition for treating heart yin deficiency and myocardial fibrosis and application thereof. The traditional Chinese medicine composition is prepared from the following raw medicinal materials in parts by weight: 5-13 parts of lily, 5-13 parts of radix ophiopogonis, 3-9 parts of ginseng, 5-13 parts of radix scrophulariae, 3-9 parts of semen boitae and 1-5 parts of schisandra chinensis. The invention also provides a preparation method of the composition. The composition has the effects of reinforcing qi, nourishing yin, calming the heart and tranquilizing the mind, and can be used for preparing medicines for treating heart-yin deficiency and myocardial fibrosis or improving heart-yin deficiency symptoms. Experimental results show that the traditional Chinese medicine composition can significantly improve the heart function of a chronic heart failure model mouse, inhibit myocardial cell hypertrophy and collagen deposition, and down-regulate fibrosis-related gene expression. Clinical observation shows that the traditional Chinese medicine can effectively relieve the symptoms of palpitation, insomnia, dysphoria with smothery sensation and the like of patients with heart yin deficiency. The traditional Chinese medicine composition is clear in formula and controllable in quality, and a novel safe and effective traditional Chinese medicine choice is provided for treating heart yin deficiency related myocardial fibrosis.

The present invention provides a pharmaceutical composition containing Scrophularia or its extract and its use. Compared with the prescription composed of honeysuckle, Scrophularia, angelica and liquorice, the single drug or its active component of the present invention can effectively alleviate joint damage in acute gouty arthritis (AGA) model mice, collagen antibody-induced arthritis (CAIA) model mice and collagen-induced arthritis (CIA) model mice by regulating neutrophil activity, reducing neutrophil migration, and alleviating immune damage caused by inappropriately activated neutrophils. It further confirms that the new strategy of treating diseases related to abnormal neutrophil activation by targeting neutrophils is feasible.

The present invention provides a Chinese medicine composition for treating Yin deficiency and phlegm heat syndrome of Graves' disease and its application. According to weight, the Chinese medicine composition comprises: 9-30 parts of Prunella Vulgaris, 9-40 parts of Scrophularia, 15-30 parts of raw oyster, 9-30 parts of Fritillaria Thunbergii, 9-30 parts of White Peony Root, and 9-30 parts of Rhizoma Dioscoreae. The Chinese medicine composition is screened for Chinese medicine prescription according to the theory of traditional Chinese medicine and accurate theory of TCM syndrome differentiation and treatment, and the formula is rigorous, the number of medicinal flavors is small, and for Graves' disease patients with Yin deficiency and phlegm heat syndrome in TCM syndrome differentiation, it can effectively reduce goiter, reduce FT3 and FT4 levels of Graves' disease patients, regulate TSH levels, reduce TRAb and TPOAb levels, and has the advantages of definite efficacy, convenient use, high safety, few adverse reactions, wide application range, etc. in treating Yin deficiency and phlegm heat syndrome of Graves' disease, and is better than conventional anti-thyroid western medicine treatment alone when used in combination with conventional anti-thyroid western medicine, and plays a synergistic effect.

The invention discloses a traditional Chinese medicine composition and medicine for treating and / or assisting in treating children herpes stomatitis and application of the traditional Chinese medicine composition, the traditional Chinese medicine composition comprises radix scrophulariae, radix ophiopogonis, platycodon grandiflorum and raw liquorice, the radix scrophulariae and the radix ophiopogonis are used as main medicines in the traditional Chinese medicine composition, the radix scrophulariae is used for removing stasis and detoxifying, cooling blood and clearing heat, and decreasing internal heat and nourishing yin; radix ophiopogonis can promote salivation, benefit stomach, nourish yin, moisten lung, resist inflammation and relieve pain; the platycodon grandiflorum is used for detoxifying and clearing heat, diminishing swelling and inducing diuresis, relieving exterior syndrome and ventilating lung, and soothing the nerves and stabilizing the mind; all the medicines have a synergistic effect, so that the effects of resisting inflammation, easing pain, dispelling wind, relieving depression, clearing away heat and toxic materials are achieved. Chlortetracycline glycerin has the effects of resisting viruses, diminishing inflammation, sterilizing, relieving pain and the like. According to the medicine, the traditional Chinese medicine composition is combined with aureomycin to assist in treatment of herpetic stomatitis, the traditional Chinese medicine composition is used for internal treatment, aureomycin glycerin is used for external treatment, internal treatment and external treatment are performed at the same time, the disease course of sick children can be remarkably shortened, symptoms are improved, and side effects are reduced.

The invention relates to a traditional Chinese medicine composition for treating blurred vision and muscae volitantes and a preparation method thereof. The invention belongs to the technical field of traditional Chinese medicines, and is helpful for relieving symptoms such as blurred vision and muscae volitantes. The formula comprises the following components: fructus lycii, flos chrysanthemi, herba taraxaci, radix ophiopogonis, pericarpium citri reticulatae fried with honey and bran, cortex fraxini, semen cuscutae, dendrobium officinale, soft talc, rhizoma coptidis, radix cynanchi paniculati, radix scutellariae, fried semen cassiae, fried fructus viticis, radix rehmanniae praeparata, prepared fructus corni, cortex moutan, rhizoma dioscoreae with honey and bran, white poria, rhizoma alismatis and bear gall, wherein the fructus lycii, the flos chrysanthemi, the herba taraxaci, the cortex fraxini, the semen cuscutae and the fried fructus viticis have the effects of clearing away heat and toxic materials, nourishing the liver and improving eyesight and the like; through the combined effect of various herbal medicine components, compared with similar products, the effect is better, and compared with western medicines, the Chinese herbal medicines reduce the potential safety hazard of medicine taking. The traditional Chinese medicine composition has the remarkable effects of clearing away heat and toxic materials, nourishing the liver, improving eyesight and relieving eye fatigue and blurred vision, muscae volitantes and other symptoms caused by overuse of eyes, and is safe and effective after being taken for a long time.

The invention discloses deodorized crocodile burn and scald oil and a preparation method thereof, and belongs to the technical field of traditional Chinese medicine formulas. The deodorized crocodile burn and scald oil provided by the invention is prepared from compound traditional Chinese medicines and crocodile oil, the compound traditional Chinese medicine comprises the following components: paeonia ostii, borneol, mint, coptis chinensis, rhizoma bletillae, houttuynia cordata, angelica sinensis, honeysuckle, gardenia, astragalus membranaceus and radix scrophulariae. The crocodile grease and the traditional Chinese medicinal materials are reasonably matched, so that the effective components of the crocodile grease are reserved, and the proportion of unsaturated fatty acid is as high as 65% or above. The ointment adopts a pure traditional Chinese medicine formula, realizes the purposes of deodorization, corrosion prevention and synergy without adding any chemically synthesized essence and preservative, promotes wound healing of burns and scalds, belongs to a pure traditional Chinese medicine preparation, is convenient to externally use, has no toxic or side effect, and is low-carbon and environment-friendly.

The invention belongs to the technical field of traditional Chinese medicines, and particularly relates to an external traditional Chinese medicine composition capable of relieving gouty arthritis and a preparation method thereof. The traditional Chinese medicine composition is prepared from the following raw materials in parts by weight: 25 to 40 parts of sappan wood, 20 to 40 parts of flos carthami, 20 to 40 parts of radix et rhizoma rhei, 10 to 25 parts of cortex phellodendri, 10 to 25 parts of dragon's blood, 10 to 30 parts of radix angelicae, 10 to 20 parts of radix scrophulariae and 5 to 20 parts of borneol. Sappan wood, safflower, rhubarb, phellodendron, dragon's blood, dahurian angelica root, radix scrophulariae and borneol are combined according to a specific ratio to realize a synergistic effect, the formula is simple and strong in effect, the pain relieving effect on acute and chronic gouty arthritis is obvious, blood uric acid can be reduced in an auxiliary manner, and the traditional Chinese medicine composition has a good application prospect.

The application provides a traditional Chinese medicine composition for treating schizophrenia, which is prepared from the following raw materials: gypsum 380-650 parts by weight, rehmannia 180-500 parts by weight, scrophularia 70-280 parts by weight, dogwood 70-280 parts by weight, nacre 380-650 parts by weight, turtle shell 70-280 parts by weight, poria 50-250 parts by weight, radix curculiginis 50-250 parts by weight, curcuma 150-400 parts by weight, salvia 150-400 parts by weight, and siler 45-210 parts by weight.

This invention discloses a fermented traditional Chinese medicine product, its preparation method, and its application, belonging to the field of traditional Chinese medicine fermentation technology. The product uses peppermint, astragalus, wolfberry, mulberry bark, anemarrhena, arborvitae leaf, scrophularia, cimicifuga, elsholtzia, angelica, lily, ginkgo, licorice, schisandra, eleutherococcus senticosus, ophiopogon japonicus, and dried ginger as raw materials, sorghum as a co-fermentation raw material, and brewing liquid as a fermentation enhancer. The process involves pretreatment of the traditional Chinese medicine, co-cooking with sorghum, saccharification with small-grain starter, segmented fermentation, extraction and purification, and post-treatment. This invention utilizes a "compound traditional Chinese medicine ~ sorghum" co-fermentation system, combined with the microbial community and active substances rich in brewing liquid, to increase the dissolution rate of active ingredients such as astragaloside A, lily polysaccharide, and wolfberry polysaccharide in the traditional Chinese medicine by more than 50%, while simultaneously converting them into easily absorbed small molecule derivatives. The finished product has an alcohol content controlled at 6-8 degrees, which not only promotes the absorption of active ingredients but also possesses synergistic effects of clearing the lungs and regulating qi, tonifying qi and benefiting the lungs, moistening the lungs and relieving cough, and clearing heat and resolving phlegm. The process enables the resource utilization of yellow water from brewing, reducing costs by 35%, and the product exhibits excellent stability, making it suitable for industrial production. It also has significant value in the field of lung function regulation and health care.

The invention provides a traditional Chinese medicine composition for treating thyroid nodules, which is prepared from twelve medicinal materials including poria cocos, roasted rhizoma atractylodis macrocephalae, rhizoma pinellinae praeparata, honey-fried licorice root, radix bupleuri, radix paeoniae alba, moutan bark, radix scrophulariae, raw oyster shell, vinegar turtle shell, platycodon grandiflorum and semen armeniacae amarae, and a specific process that the raw oyster shell and the vinegar turtle shell are crushed to 3-5mm and then decocted is adopted. According to the treatment principle of tonifying spleen and reducing phlegm, soothing liver and regulating qi, lifting and guiding and softening hardness to dissipate stagnation, platycodon grandiflorum is used for opening and diffusing lung qi carrying medicine to ascend, semen armeniacae amarae is used for depressing qi and reducing phlegm and guiding qi to descend, qi movement thrust of ascending and descending is formed, and the hardness softening medicine can efficiently reach the neck focus; meanwhile, spleen strengthening and healthy energy protection are achieved, and bitter cold is prevented from hurting middle- Through clinical observation of 120 thyroid nodule patients, the total effective rate is 96.7%, the obvious effective rate is 90.0%, pharyngeal foreign body sensation disappears in 7-14 days on average, the nodule volume average reduction rate is 75.8%, the recurrence rate is only 3.3% after 6 months, and the occurrence rate of anorexia and loose stool of the patients is 0%. A contrast experiment further proves that the nodule reduction rate is only 45.5% after the platycodon grandiflorum and the bitter apricot kernels are removed. The traditional Chinese medicine composition can quickly soften and reduce nodules, thoroughly dissolve phlegm stasis, protect healthy qi and reduce relapse, and overcomes the defects of spleen deficiency, excessive phlegm, anorexia, loose stool and drug withdrawal and relapse which are easily caused by traditional bitter and cold prescriptions of selfheal, seaweed and the like.

The invention discloses a radix scrophulariae endophytic fungus and application thereof in promoting growth of radix scrophulariae, and belongs to the technical field of plant growth promotion. The endophytic fungus is separated from a Scrophularia ningpoensis living body of a scrophulariaceae scrophulariaceae plant by adopting an endophytic fungus separation and purification technology, belongs to fungi of ascomycophyta, Alternaria, Alternaria and Bordetella, is preserved in the China General Microbiological Culture Collection Center on January 23, 2024, is classified and named as Boeremia exigua SNF128, and has the characteristics that the endophytic fungus is named as Scrophularia ningpoensis SNF128; the preservation number of the strain is CGMCC (China General Microbiological Culture Collection The invention also discloses application of the endophytic fungi: the growth of radix scrophulariae tissue culture seedlings is promoted, the dry weight is increased by 62.07%, and the plant height, the root length, the leaf length and the leaf width are respectively increased by 73.29%, 22.41%, 43.37% and 24.02%.

The present invention provides a cucurbitacin compound, its preparation method, and application, belonging to the field of pharmaceutical chemistry. The cucurbitacin compound represented by Formula I is extracted and isolated from Scrophularia purpurogenum. This furanocoumarin compound can inhibit the phosphorylation of STAT3 in triple-negative breast cancer cells and further affect the expression of downstream apoptosis-related proteins PARP and Caspase3, promoting apoptosis in triple-negative breast cancer cells, thereby inhibiting the growth of triple-negative breast cancer. It has broad application prospects in the preparation of drugs for the prevention and / or treatment of triple-negative breast cancer. #imgabs0# Formula I.

The invention relates to the technical field of traditional Chinese medicine preparations, and discloses an anti-new coronavirus compound traditional Chinese medicine preparation in order to solve the problem that an existing new coronavirus medicament is poor in effect of inhibiting proliferation and reproduction of viruses and bacteria. Comprising the following components in parts by weight: perilla leaf, ephedra, divaricate saposhnikovia root, scutellaria baicalensis, rhizoma acori graminei, platycodon grandiflorum, almond, rhizoma atractylodis, radix scrophulariae, radix bupleuri, paris polyphylla, radix puerariae, fructus aurantii, agastache rugosus and liquorice. The anti-new coronavirus compound traditional Chinese medicine disclosed by the invention has the effects of relieving exterior syndrome and dispelling cold, clearing lung and eliminating phlegm, abating fever and inducing resuscitation, inhibiting proliferation and reproduction of viruses and bacteria, and improving body immunity; the medicine is applied to clinical tests, new coronavirus in the body of a patient after taking the medicine stops copying within 48 hours, and the medicine is superior to medicines such as arbidol, interferon multiple times and albivudine which are clinically used.

The invention relates to the technical field of traditional Chinese medicine compositions, in particular to a traditional Chinese medicine composition for treating cerebral hemorrhage and a preparation method thereof. The invention provides a traditional Chinese medicine composition for treating cerebral hemorrhage. The traditional Chinese medicine composition is prepared from the following components in parts by mass: 20-26 parts of cortex mori radicis, 18-22 parts of radix scrophulariae, 18-22 parts of rhizoma nardostachyos, 16-20 parts of rheum officinale, 15-19 parts of earthworm, 14-18 parts of polygala tenuifolia, 11-15 parts of raw dens draconis, 8-12 parts of nacre mother of pearl, 6-10 parts of concha haliotidis, 5-7 parts of rhizoma polygonati, 4-6 parts of codonopsis pilosula and 4-6 parts of roasted rhizoma atractylodis macrocephalae. The traditional Chinese medicine composition can stop bleeding, cool blood, calm liver wind, restore consciousness, induce resuscitation, reduce intracranial pressure and clean up intracranial hematoma under the synergistic effect of the traditional Chinese medicine composition, so that the technical effect of treating cerebral hemorrhage is achieved.