33 results about "Loose Stool" patented technology

The invention belongs to the technical field of traditional Chinese medicines, and particularly relates to a traditional Chinese medicine composition with an effect of preventing and treating alcoholic liver injury as well as a preparation method and application thereof. The traditional Chinese medicine composition is prepared from the following raw material medicines: radix puerariae, turmeric, ginseng, hovenia dulcis thunb, white hyacinth bean, raw oyster shell, poria cocos, raw hawthorn, biond magnolia flower, juncus effuses and albizia flower. The traditional Chinese medicine composition has the effects of soothing liver and harmonizing stomach, dispelling alcohol effect and enlivening spleen, and reinforcing qi and nourishing blood. Experimental results show that the traditional Chinese medicine composition has a good treatment effect on acute alcoholic liver injury and chronic alcoholic fatty liver, and can effectively improve the symptoms of chest rib swelling pain, reduced appetite, anorexia, abdominal distension, hiccup, belching, borborygmus and qi and loose stool caused by liver-stomach disharmony and spleen deficiency and dampness of alcoholic liver injury patients; therefore, the method has good development and utilization prospects.

To provide a nonwoven fabric for absorbent article that enables a user to recall high level of loose stool absorptivity of an absorbent article and has high loose stool absorptive capacity.SOLUTION: There is provided a nonwoven fabric for an absorbent article including a first fiber layer and a second fiber layer that are laminated in a thickness direction and including fiber fused parts at intersections between fibers. The first fiber layer includes: a plurality of recessed parts each having a space part open toward a skin surface side; and aperture parts penetrating in a thickness direction between respective ones of the neighboring recessed parts. Each of the plurality of recessed parts includes: wall parts extending vertically with respect to a plane direction of the nonwoven fabric; and a bottom part. The second fiber layer is disposed on a non-skin surface side of the first fiber layer and has protruding parts approaching areas partitioned by the wall parts from the aperture parts of the first fiber layer on an opposite surface side to the first fiber layer.SELECTED DRAWING: Figure 1

The invention relates to the technical field of traditional Chinese medicine, in particular to a traditional Chinese medicine composition for treating co-disease of liver depression and spleen deficiency type depressive state and IBS (irritable bowel syndrome). The composition comprises radix pseudostellariae, poria cocos, raw coix seeds, fingered citron, polygala tenuifolia, roasted rhizoma atractylodis macrocephalae, lotus seed pulp, mint, roses, lilies, raw fructus gardeniae, fermented soybeans and raw hawthorn fruits. Liver soothing, depression relieving, spleen strengthening and heart nourishing are taken as core treatment rules, heat clearing, restlessness relieving, digestion promoting and stagnation removing are also taken, and the complex pathogenesis that the two are causal to each other is formed for gastrointestinal dysfunction caused by emotional discomfort. The formula is characterized in that the three internal organs of the heart, the liver and the spleen are treated at the same time, the four methods of tonifying, dredging, clearing and eliminating are used at the same time, balance is achieved between qi regulating and healthy qi supporting, and the formula is suitable for patients suffering from complex heart and body diseases with low mood, anxiety, dysphoria, insomnia, amnesia, abdominal fullness, inappetence, loose stool or loose stagnation.

A method for constructing a diarrhea model of experimental mice using a combined medicament, characterized in that: using mice as the modeling object, after adaptive feeding, the combined medicament is given by gavage once a day for 7 consecutive days. After the gavage each day, the mice are placed in a breeding cage lined with filter paper, and the diarrhea situation is observed 4 hours after gavage; wherein the combined medicament is prepared by extracting senna leaf and fibraurea recisa. A method for constructing a diarrhea model of experimental mice using a combined medicament has good repeatability in the construction method, is simple and convenient, has good compliance of mice during the modeling process, high compliance, good living state, no restlessness phenomenon, small weight loss, long duration after modeling, which can be up to more than 28 hours, and the loose stool rate of mice is relatively high, comparable to that of the conventional senna leaf modeling, but the mice have better tolerance compared with the traditional senna leaf modeling. During the modeling process, the weight loss of mice is relatively small, and the modeling success rate is improved.

The present invention discloses a physical laxative, comprising an electric laxative head, the electric laxative head comprising a tubular handle, a sewage collecting sleeve, a stirring rod and a driving motor, the sewage collecting sleeve being tubular, the rear end of which is docked with the front end of the tubular handle, the front edge of which is against the patient's anus, the driving motor being installed in the tubular handle, the front end of the stirring rod being inserted into the patient's hard stool, the rear end of which is connected to the driving motor through the sewage collecting sleeve, the front end of the stirring rod being provided with a water spray hole, the rear end of which is provided with a water inlet hole connected to the water spray hole, the water inlet hole being connected to a water supply device, and the rear end of the tubular handle being connected to a sewage pipe. The present invention uses physical stirring and spraying of liquid to break up and soften the hard stool that causes constipation, and then discharges the loose stool through the sewage pipe. This not only can quickly remove hard stool, solve the constipation problem of middle-aged and elderly people, and alleviate the pain of patients, but also can avoid contaminating bedding and reduce the workload of nursing staff.

The invention belongs to the field of traditional Chinese medicine compositions, and relates to a traditional Chinese medicine composition and traditional Chinese medicine granules for treating diarrhea type spleen-kidney yang deficiency IBS, the traditional Chinese medicine composition comprises the following raw materials by weight: 6-12 parts of ginseng, 5-15 parts of albizia flower, 5-15 parts of fructus aurantii, 8-15 parts of rhizoma atractylodis, 8-15 parts of bighead atractylodes rhizome, 2-5 parts of cornu cervi pantotrichum, 2-6 parts of fructus evodiae, 3-9 parts of cordyceps sinensis, 15-20 parts of oven earth, 8-15 parts of red halloysite, 3-10 parts of fructus chebulae, and 5-9 parts of honey-fried licorice root. According to clinical tests for many years, the traditional Chinese medicine composition can be used for effectively relieving symptoms such as stomachache, loose stool and diarrhea of diarrhea type spleen-kidney yang deficiency irritable bowel syndrome patients, improving spleen and stomach functions of the patients and improving life quality, and has the advantages of quick response, stable curative effect, high total effective rate, no toxic or side effect, no toxic or side effect, no toxic or side effect and the like. The recurrence rate is low, and the like.

The invention belongs to the technical field of intestinal microorganisms, and particularly relates to bacteroides polydeformation ZF-8 and application thereof in preparation of drugs and food for treating and / or preventing inflammatory bowel diseases. The invention relates to a bacterial strain, in particular to a bacterial strain ZF-8, and the bacterial strain ZF-8 is a bacterial strain ZF-8. The strain is separated from the intestinal tract of a healthy human body and is preserved in the China Center for Type Culture Collection (CCTCC), and the preservation number is CCTCC NO: M 2025618. The bacterial strain can protect colorectal mucosa from being damaged and repair the damaged intestinal mucosa, so that symptoms such as loose stool, hematochezia and colorectal shortening are improved, weight loss caused by intestinal injury and inflammation is relieved, and finally, the inflammatory bowel disease is treated.

This invention belongs to the field of intestinal microbiome technology, and particularly relates to the application of a capsular polysaccharide derived from Bacteroides Salilsii CSP6 in the treatment and / or prevention of inflammatory bowel disease. The Bacteroides Salilsii strain is... Bacteroides salyersiae CSP6. This strain was isolated from the intestine of healthy humans and deposited at the China Center for Type Culture Collection (CCTCC), accession number CCTCC NO: M 20221993. In vivo experiments showed that the capsular polysaccharide derived from Bacteroides Salieris CSP6 can protect the colorectal mucosa from damage and promote the repair of damaged intestinal mucosa, thereby improving symptoms such as loose stools, rectal bleeding, and shortened colon and rectum, reducing weight loss caused by intestinal damage and inflammation, and ultimately exerting a therapeutic effect on inflammatory bowel disease.

This invention relates to the field of probiotics technology, specifically to a Bifidobacterium bifidum PlantBase-931 for removing dampness and aiding weight loss, its fermented products, preparation methods, and applications. Bifidobacterium bifidum PlantBase-931 can increase the levels of GAS and MTL in the blood, strengthen the spleen and stomach, promote the expression of AQP3 and AQP4 in colon tissue, and accelerate the elimination of dampness from the body, thus benefiting obese individuals in their weight loss journey. The PlantBase-931 fermented product is prepared by staged fermentation, spray drying, and vacuum freeze-drying of the composition. The composition consists of the following ingredients in parts by weight: navel orange, hawthorn, grape, lychee, papaya, coix seed, winter melon, white sugar, and purified water. The resulting fermented product can reduce IL-1β inflammation levels in the spleen, repair spleen damage, and improve loose stool symptoms in obese individuals.

The present application relates to a kind of traditional Chinese medicine composition of invigorating spleen and dampness and its preparation method and application, including the following weight parts of raw materials: 7-14 parts of ginseng, 10-20 parts of fried white bean, 10-20 parts of tuckahoe, 7-14 parts of orange peel, 15-30 parts of corn silk, 10-20 parts of gardenia, 12-24 parts of white lily root, 13-26 parts of kudzu root, 6-12 parts of white peony root, 6-12 parts of perilla leaf, 6-12 parts of shiitake mushroom, 1-4 parts of licorice root. It has the effect of invigorating spleen and dampness, ascending clear and descending turbid, promoting water and reducing swelling. It is used for body fatigue, limb soreness, edema, vomiting, diarrhea, polydipsia, loose stool and other symptoms caused by dampness. And it can be used as a health drink for chronic diseases related to dampness. The present application has a good application prospect with unique formula and no toxic side effects.

This invention provides a traditional Chinese medicine composition for treating hypertension, prepared from the following raw materials in the indicated weight ratios: 8-12 parts of Achyranthes bidentata, 8-12 parts of Leonurus japonicus, 12-18 parts of Alisma plantago-aquatica, 8-12 parts of Scutellaria baicalensis, 8-12 parts of Paeonia lactiflora, 8-12 parts of Atractylodes lancea, and 4-6 parts of Carthamus tinctorius. This invention also provides a method for preparing the composition and its uses. This traditional Chinese medicine composition can effectively control blood pressure in young and middle-aged patients with hypertension diagnosed as damp-heat obstruction syndrome. By preparing a decoction from the seven herbs in the composition using specific dosages and traditional Chinese medicine processing techniques, it can clear heat and dry dampness, promote blood circulation and diuresis, and lower blood pressure. Simultaneously, it effectively improves clinical symptoms of damp-heat obstruction syndrome such as persistent fever and sweating, thirst without excessive drinking, epigastric fullness and nausea, restlessness, loose stools with yellow color, and scanty dark urine, providing a new medication option for clinical use.

The utility model discloses an excrement sample collecting, storing and sampling tube with a simple picking function, and relates to the technical field of medical detection instruments. The excrement sample collection and storage sampling tube with the simple picking function comprises a tube body, a tube cover is detachably connected to the upper end of the tube body, a collection mechanism is arranged on the tube cover and can be used for picking an excrement sample, and the collection mechanism comprises a clamping assembly, a clamping connection rod, a clamping connection rod, a clamping connection rod and a clamping connection rod, two groups of clamping rods are arranged, hollow hemispheres are fixed at the lower ends of the two groups of clamping rods, and the hollow hemispheres are symmetrically arranged and form a complete sphere when being combined; the problems that a sampling device of a traditional excrement sampling pipe is in a rod type or a flat spoon type, the sampling amount is difficult to control during sample collection, and effective excrement samples with actual utilization value are difficult to collect for a subject with slightly loose excrement are solved.

This invention provides the application of *Pleurotus oosporum* polysaccharide in the preparation of drugs and health foods that regulate intestinal barrier function or protect against intestinal damage-related diseases. Its protective effect against a mouse model of intestinal damage induced by sodium dextran sulfate was investigated. Results showed that *Pleurotus oosporum* polysaccharide significantly improved symptoms such as weight loss, loose stools, and colonic atrophy caused by intestinal damage in mice, reduced the disease activity index, inhibited colonic epithelial destruction, inflammatory cell infiltration, and goblet cell necrosis, and enhanced intestinal mucosal barrier function. As a fungus, *Pleurotus oosporum* has high safety and is a potential source of active ingredients against intestinal damage, showing promising development prospects in intestinal barrier protection.

The invention discloses a noninvasive diagnosis model for infant food allergy. The noninvasive diagnosis model is used for early recognition of infant food allergy. The model is established through multi-factor Logistic regression based on clinical common symptoms and risk factors, and comprises six variables: eczema severity, stool character, hemafecia, respiratory system symptoms, growth retardation and allergic disease family history. Various variables are endowed with different weights according to objective statistical results to form a model scoring formula: score = 0.23 * eczema (mild) + 1.02 * eczema (moderate) + 1.35 * eczema (severe) + 0.47 * stool (loose stool) + 1.42 * stool (watery stool) + 1.60 * hemafecia + 0.78 * growth retardation + 1.19 * respiratory system symptoms + 1.36 * allergic disease family history. Through verification of a training set and an independent test set, the model has relatively high diagnosis efficiency (AUC is about 0.86-0.87), when the model score is greater than or equal to 3.19, the food allergy is judged, and the optimal diagnosis effect can be achieved. The model is non-invasive, simple and convenient in evaluation process, small in error and high in compliance, and can assist clinicians in diagnosing infant food allergy.

The utility model provides an anal tube which comprises a tube body and an expansion part, the two ends of the tube body in the length direction are an imbedding end and an exposed end respectively, a tube cavity is defined by the inner wall of the tube body, an imbedding opening is formed in the side, close to the imbedding end, of the tube body, the expansion part is connected with the tube body, and the expansion part is connected with the tube body. The expansion part has at least two working states, namely a dry state and a liquid absorption state, and when the expansion part is in the liquid absorption state, the side, deviating from the pipe body, of the expansion part extends outwards in the radial direction of the pipe body. According to the anal tube, the expansion part is additionally arranged on the tube body, the expansion part can be converted into the liquid suction state after absorbing part of water of loose excrement, the expansion part in the liquid suction state extends outwards in the radial direction of the tube body, and the expansion part in the liquid suction state plays a role in preventing the tube body from being separated from the anus; meanwhile, the expansion part absorbs liquid to prevent leakage of loose excrement.

The present invention belongs to the technical field of medical devices and discloses a routine stool collection auxiliary device, comprising a mounting seat, the bottom of which is provided with a fixing assembly suitable for toilets and squat toilets, the top of which is slidably connected to a stool collection box and a mounting block, the top of which is rotatably connected to the mounting box, a driven gear rotatably engaged within the mounting box, the driven gear being coaxially provided with a clamping assembly away from the mounting box, the driven gear being transmission-connected to a scooping assembly provided within the mounting box, and a suction assembly being provided on the top of the clamping assembly. The stool sample collection auxiliary device of the present invention is applicable to both toilets and squat toilets, and can also be used to collect stool samples of different types (formed stool, loose stool, watery stool). Stool sample collection is convenient, clean, and hygienic, and can also improve the patient's comfort when using the toilet, reduce the patient's psychological discomfort, and increase the patient's willingness to undergo a stool examination.

The invention relates to the technical field of traditional Chinese medicines, in particular to application of a traditional Chinese medicine composition in preparation of a medicine for preventing and / or treating antibacterial drug related diarrhea. Experiments show that the traditional Chinese medicine composition can obviously improve diarrhea symptoms of mice with antibacterial drug-related diarrhea, reduce loose stool rate, reduce faeces character grading scores, relieve colon tissue pathological damage of the mice with antibacterial drug-related diarrhea, enhance intestinal barrier function and regulate intestinal flora abundance.

This invention discloses a traditional Chinese medicine composition, its preparation, and its application for treating solid and cystic thyroid nodules caused by liver stagnation and spleen deficiency. The traditional Chinese medicine composition of this invention, by weight, comprises the following raw materials: 20-30 parts of Prunella vulgaris, 20-30 parts of Taraxacum mongolicum, 10-15 parts of Salvia miltiorrhiza, 6-9 parts of Bupleurum chinense (processed with vinegar), 9-10 parts of Citrus aurantium (fried), 9-12 parts of Paeonia lactiflora, 10-15 parts of Cyperus rotundus, 20-30 parts of Coix lacryma-jobi, 15-20 parts of Fritillaria thunbergii, 20-30 parts of pearl powder, and 20-30 parts of oyster shell. This invention also discloses the preparation of this traditional Chinese medicine composition. The traditional Chinese medicine composition and its preparation of this invention can effectively shrink thyroid nodules and improve symptoms such as neck fullness, pulling sensation, foreign body sensation in the throat, occasional stabbing pain in the front of the neck, irritability or depression, fatigue, loose stools, and poor sleep in patients with nodules caused by liver stagnation and spleen deficiency, without affecting thyroid function.

The present invention provides an auxiliary sheet for absorbent articles that reduces slippage of absorbent articles, decreases the amount of viscous excretory fluid such as loose stools adhering to the skin, and prevents leakage of excretory fluid from behind. [Solution] The absorbent auxiliary sheet 10 has a pocket space P on the inner side in the width direction, and the absorbent auxiliary sheet 10 has a fitting part 1 having a length W1 that can be fitted in the width direction with respect to the length V1 between the outer upright base ends in the width direction in the pocket space of the three-dimensional gathered part, and a pair of positioning parts 2 that abut against the upright base end at the rear end in the longitudinal direction in the pocket space of the three-dimensional gathered part, and the ratio of the length of the fitting part along the longitudinal direction to the length in the longitudinal direction between the upright base end at the front end and the upright base end at the rear end of the three-dimensional gathered part is 0.10 or more and 0.50 or less.

The invention provides a compound feed additive for improving chicken loose stool caused by corn protein peptide. The compound feed additive consists of potassium bicarbonate and zeolite. The composite additive can effectively improve the problem of loose stool of chickens caused by excessive intake of sulfite, the growth performance of the chickens is not affected, and excessive intake of sulfite by the chickens is caused by intake of corn protein peptides.

The invention belongs to the field of Chinese medicine compositions and relates to a Chinese medicine composition and Chinese medicine granules for treating diarrhea-type spleen and kidney yang deficiency syndrome IBS. The Chinese medicine composition is composed of the following raw materials by weight: 6-12 grams of ginseng, 5-15 grams of julibrissin, 5-15 grams of fructus aurantii, 8-15 grams of atractylodes, 8-15 grams of atractylodes, 2-5 grams of pilose antler, 2-6 grams of evodia rutaecarpa, 3-9 grams of cordyceps, 15-20 grams of heartwood, 8-15 grams of red ochre, 3-10 grams of terminalia chebula, and 5-9 grams of roasted liquorice. The Chinese medicines are used together to jointly play the effects of invigorating the spleen and kidney, regulating qi and stopping diarrhea, and calming the nerves. It has been proved through many years of clinical trials that the prescription can effectively relieve the abdominal pain, loose stools, diarrhea and other symptoms of patients with diarrhea-type spleen and kidney yang deficiency syndrome irritable bowel syndrome, improve the spleen and stomach function of patients, improve the quality of life, and has the advantages of fast onset, stable efficacy, high total effective rate, low recurrence rate and the like.

The invention discloses application of cedrol in preparation of a medicine for treating acute ulcerative colitis, and belongs to the technical field of biological medicine. Experiments prove that cedrol can effectively improve DSS-induced colon injury, relieve inflammatory response, improve the intestinal mucosa barrier function, slow down weight loss caused by ulcerative colitis, reduce disease activity indexes, relieve the phenomena of colon shortening and loose stool and protect the structural integrity of colon; the invention provides a theoretical basis for researching and developing medicines for treating ulcerative colitis, and has wide clinical application value.

The invention relates to the technical field of traditional Chinese medicine compositions, in particular to a composition for treating atherosclerotic plaque and a preparation method thereof, and is technically characterized in that the composition is composed of the following components in parts by weight: 5-10 parts of astragalus membranaceus, 5-10 parts of gynostemma pentaphylla, 5-10 parts of roasted perillaseed, 5-10 parts of lotus leaf, 5-10 parts of seaweed, 7.5-20 parts of hawthorn, 5-10 parts of pollen typhae and 5-10 parts of rhizoma alismatis. , 5-10 parts of turmeric and 1.5-4 parts of red yeast rice. The composition disclosed by the invention is used for treating coronary heart disease angina, myocardial infarction, atherosclerotic plaque and lower limb atherosclerotic obliterans, has obvious curative effects, does not have other side effects except for loose stools after individual patients take the composition, and provides important guiding significance for treatment of atherosclerotic plaque and development of medicines.

The invention provides an application of Arnicolide D (Arnicolide D, ArD) in preparation of a medicine for treating colitis. Researches show that ArD has a good colitis treatment effect, and after ArD treatment is carried out on a colitis model animal, clinical symptoms of colitis can be effectively relieved, so that the DAI score is reduced, and symptoms of bloody stool and loose stool are relieved. Meanwhile, mouse colon length shortening caused by DSS can be remarkably relieved, and the effect is better than that of a positive drug; the traditional Chinese medicine composition is capable of reducing inflammatory cell infiltration, repairing intestinal mucosal barrier, inhibiting release of inflammatory factors TNF-alpha and IL-6 and reducing intestinal inflammation, so that the development process of colitis is inhibited, and the traditional Chinese medicine composition can be used for relieving inflammatory bowel diseases. Moreover, ArD is adopted for administration treatment, no obvious toxicity is caused to mice, abnormal conditions such as lesion and injury do not occur to organs of the mice, and good in-vivo safety is achieved. Therefore, the ArD provided by the invention provides more efficient and safe treatment medicines for treating colitis.

This product provides a diarrhea-suppressing material that uses common food ingredients without complex processing or treatment, and without deviating from the palatability of dogs, thereby preventing diarrhea and loose stools in dogs. [Solution] A poorly soluble soy protein material, characterized by a leucine (Leu) to glutamic acid (Glu) mass ratio of 2 or less and an NSI of 10-60%, can suppress diarrhea and loose stools in dogs with small amounts of intake. This material can be obtained as an undegraded residue from the soy peptide manufacturing process.

The invention provides a compound feed additive containing potassium bicarbonate and valonia tannin, which can effectively improve the problem of loose stool of chickens caused by replacement of soybean meal by corn protein peptide, and does not influence the growth performance of the chickens.

The invention belongs to the technical field of enteroscopes, particularly relates to an enteroscopy positioning device and a use method thereof, and provides the following scheme aiming at the existing problems that loose feces sprayed from the anus pollutes an infirmary, lubricating oil is manually smeared on the outer wall of an enteroscope, the enteroscope cannot be positioned and the like: the enteroscopy positioning device comprises a bed board and a placement groove formed in the top of the bed board; a collecting frame is placed in the containing groove, a frame body is placed in the collecting frame, a plurality of first fixing rods are fixed in the frame body, and the first fixing rods are matched with the collecting frame to be used for supporting the buttocks of a patient and collecting loose stool and intestinal contents; when enteroscopy is carried out, loose excrement sprayed out by a patient is blocked and collected through cooperation of the collecting frame, the first fixing rod and the U-shaped baffle, the infirmary is prevented from being polluted, and when the enteroscopy is inserted into the rectum, the enteroscopy can be positioned to guarantee the stability of the enteroscopy; the lubricant can be automatically smeared on the outer wall of the enteroscope when the enteroscope is inserted.

To provide an absorbent article capable of suppressing skin irritation by reducing contact between the skin and loose stool even when a large amount of loose stool is excreted.SOLUTION: An absorbent article comprising a top sheet on the skin side, a back sheet on the non-skin side, and an absorbent body disposed between the top sheet and the back sheet, wherein the top sheet and the back sheet are liquid-impermeable, a liquid-permeable second sheet is provided between the top sheet and the absorbent body, the dimension of the second sheet in the width direction is longer than the dimension of the top sheet in the width direction, and the absorbent body has a raised structure in which the dimension in the thickness direction is maximum at the center portion in the width direction and decreases continuously or stepwise toward both end portions in the width direction, the absorbent article is characterized in that the absorber has a plurality of slits reaching both ends in the width direction.SELECTED DRAWING: Figure 3

The present invention relates to the technical field of traditional Chinese medicine compositions, and specifically discloses a composition for treating atherosclerotic plaques and a preparation method thereof. The technical key points are as follows: The composition is composed of the following components in parts by weight: 5-10 parts of Astragalus membranaceus, 5-10 parts of Gynostemma pentaphyllum, 5-10 parts of roasted Perilla seeds, 5-10 parts of lotus leaf, 5-10 parts of Sargassum, 7.5-20 parts of Hawthorn Fruit, 5-10 parts of Pollen Typhae, 5-10 parts of Alisma orientale, 5-10 parts of Curcuma longa, and 1.5-4 parts of Monascus purpureus. The composition of the present invention has obvious curative effects in the treatment of coronary heart disease angina pectoris, myocardial infarction, atherosclerotic plaques, and lower extremity atherosclerotic obliterans. Except for loose stools in some patients after taking the medicine, no other side effects have been found, which provides important guiding significance for the treatment of atherosclerotic plaques and the development of drugs.

Provided herein are methods of managing feline diabetes, said methods include administering to a feline in need thereof a total daily dosage of about 5 to 50 mg of Compound 1, having the formula:or a pharmaceutically acceptable form thereof. Also provided herein are methods of managing feline diabetes by administering to a feline in need thereof an effective amount of a SGLT inhibitor, wherein said effective amount is no more than 10 to 30% of the dose required to produce an elevated frequency of diarrhea or loose stool in a healthy feline.