16 results about "Gastrointestinal dysfunction" patented technology

The invention relates to the technical field of traditional Chinese medicine preparations, in particular to a traditional Chinese medicine compound preparation for preventing and treating sepsis based on intestinal treatment and gasification regulation and a preparation method and application of the traditional Chinese medicine compound preparation. The composition is prepared from the following medicinal materials in parts by weight: 3 to 10 parts of rheum officinale, 5 to 10 parts of fructus aurantii, 5 to 10 parts of radix aucklandiae, 10 to 15 parts of fructus gardeniae, 10 to 15 parts of dandelion, 10 to 15 parts of fructus forsythiae, 10 to 15 parts of herba artemisiae scopariae, 10 to 15 parts of rhizoma atractylodis, 10 to 15 parts of poria cocos, 10 to 15 parts of radix paeoniae rubra, 10 to 15 parts of radix salviae miltiorrhizae, 15 to 20 parts of astragalus membranaceus, 10 to 15 parts of rhizoma anemarrhenae, 10 to 15 parts of fructus cannabis, 10 to 15 parts of semen pruni and 3 to 6 parts of raw liquorice. The traditional Chinese medicine compound provided by the invention considers the treatment rules of relaxing bowels, purging heat, promoting qi circulation, removing stagnation, detoxifying, dispersing blood stasis, reinforcing qi, nourishing yin and the like, and also considers the effects of relaxing bowels, regulating qi and supporting healthy qi, various diseases of sepsis patients can be remarkably improved through the synergistic effect of the medicines in the formula, and the traditional Chinese medicine compound especially has an obvious curative effect on gastrointestinal dysfunction. A novel traditional Chinese medicine treatment thought is provided for clinical treatment of sepsis diseases.

The application discloses a composition, which comprises hydrolyzed protein; the hydrolyzed protein comprises hydrolyzed whey protein and hydrolyzed casein protein, the weight ratio of the hydrolyzed whey protein and the hydrolyzed casein protein is (70-95):(5-30), the amino acid nitrogen content in the hydrolyzed protein is (1.0-3.0) g / 100 g, the proportion of protein hydrolysate with a relative molecular mass distribution <1000 in the hydrolyzed protein is 34-70%, the peptide content (calculated on a dry basis) in the hydrolyzed protein is not less than 33 g / 100 g, and the total free amino acid content in the hydrolyzed protein is not less than 1 g / 100 g. The composition can effectively treat diarrhea and is suitable for people with gastrointestinal dysfunction and severe patients with diarrhea symptoms.

The application belongs to the technical field of traditional Chinese medicine, and particularly relates to an external traditional Chinese medicine composition with the effects of promoting qi circulation and dredging bowels, regulating cold and heat, ascending clear and descending turbid, an external traditional Chinese medicine ointment, a preparation method and application. The external traditional Chinese medicine composition is composed of the following raw medicinal materials: dried ginger, cassia twig, fried atractylodes, radix codonopsis, raw rhubarb, goldthread, immature orange fruit, magnolia officinalis, fried pinellia and licorice. The external traditional Chinese medicine composition has the effects of promoting qi circulation and dredging bowels, regulating cold and heat, ascending clear and descending turbid, and has a remarkable curative effect on treating chronic obstructive pulmonary disease combined with gastrointestinal dysfunction, so that the function of the patient's spleen and stomach is recovered, the clinical symptoms of the patient are effectively relieved, and the quality of life is improved, and there is no problem of the patient not being easy to tolerate and the gastrointestinal burden being aggravated.

The invention relates to the technical field of traditional Chinese medicine, in particular to a traditional Chinese medicine composition for treating co-disease of liver depression and spleen deficiency type depressive state and IBS (irritable bowel syndrome). The composition comprises radix pseudostellariae, poria cocos, raw coix seeds, fingered citron, polygala tenuifolia, roasted rhizoma atractylodis macrocephalae, lotus seed pulp, mint, roses, lilies, raw fructus gardeniae, fermented soybeans and raw hawthorn fruits. Liver soothing, depression relieving, spleen strengthening and heart nourishing are taken as core treatment rules, heat clearing, restlessness relieving, digestion promoting and stagnation removing are also taken, and the complex pathogenesis that the two are causal to each other is formed for gastrointestinal dysfunction caused by emotional discomfort. The formula is characterized in that the three internal organs of the heart, the liver and the spleen are treated at the same time, the four methods of tonifying, dredging, clearing and eliminating are used at the same time, balance is achieved between qi regulating and healthy qi supporting, and the formula is suitable for patients suffering from complex heart and body diseases with low mood, anxiety, dysphoria, insomnia, amnesia, abdominal fullness, inappetence, loose stool or loose stagnation.

1. Name of the product in this design: External gastrointestinal pacing therapy device. 2. Purpose of this design: To relieve and eliminate symptoms of gastrointestinal dysfunction. 3. The key design feature of this product is its shape. 4. The image or photograph that best illustrates the design's key points: a 3D model.

The invention belongs to the technical field of traditional Chinese medicines, and particularly relates to a traditional Chinese medicine enema composition for treating postoperative gastrointestinal dysfunction and application thereof. The traditional Chinese medicine enema composition for treating postoperative gastrointestinal dysfunction is prepared from the following raw materials: fried semen raphani, fructus aurantii stir-fried with bran, fried fructus aurantii immaturus, raw liquorice, radix paeoniae alba, rheum officinale, rhizoma zingiberis, codonopsis pilosula, bupleurum chinense, ginger-processed cortex magnoliae officinalis and lignum dalbergiae odoriferae. The prescription is based on the core theories of'six internal organs are used for dredging ', 'qi movement is caused by rising and falling' and'healthy energy is strengthened and attacks evil 'in the traditional Chinese medicine, and the prescription aims to dredge triple jiao, smooth qi movement, dredge the internal organs, purge turbidity and strengthen the healthy energy. The whole formula takes'dredging and descending 'as a main component, 'ascending and dispersing' as an auxiliary component and'tonifying 'as an assistant component, so that a precise compatibility system with simultaneous ascending and descending and simultaneous purgation and tonification is formed. The traditional Chinese medicine enema composition is remarkable in clinical curative effect, low in recurrence rate and free of adverse reaction, the preparation process is simple and easy to implement and easy to popularize and apply, and the traditional Chinese medicine enema composition has good social benefits and economic benefits.

The application belongs to the technical field of traditional Chinese medicines, and provides a compound traditional Chinese medicine and application thereof in preparation of a medicine for preventing and treating postoperative gastrointestinal dysfunction. The compound traditional Chinese medicine is composed of radix codonopsis extract, radix bupleuri extract, fructus aurantii extract, radix astragali extract and radix angelicae extract with a mass ratio of 1:3-4:1-2:3-5:2-3. Animal experiments show that the compound traditional Chinese medicine can significantly reverse the decrease of postoperative gastrointestinal motility function, reverse the changes of gastrointestinal hormones VIP and MTL, and help and promote the recovery of postoperative gastrointestinal motility function. The compound traditional Chinese medicine has reasonable formula, is convenient to use, and has a wide application range, and has curative effects on the recovery of postoperative gastrointestinal function caused by various conditions.

This invention discloses a liposomal curcumin composition for regulating the gastrointestinal tract and its applications, belonging to the technical fields of food and health food. The composition consists of 60-80nm liposomal curcumin, prebiotics, and cardamom extract. The liposomal curcumin uses food-grade phospholipids to construct a biomimetic bilayer structure with an encapsulation rate ≥80%, ethanol residue ≤0.5‰, a 2-hour release rate <33% in simulated gastric juice, and a 2-hour release rate >80% in simulated intestinal juice at pH 7.4. The cardamom extract is a water or alcohol extract of cardamom, with a content of 10-60mg per serving. This invention achieves targeted sustained release of curcumin into the intestine through precise particle size control, synergistically regulating gut microbiota with prebiotics and enhancing gastrointestinal motility with cardamom extract. It regulates gastrointestinal function from multiple dimensions, including mucosal repair, microbiota balance, and motility improvement. The bioavailability is more than 18 times higher than ordinary curcumin. The product has high safety and good stability and can be prepared in various dosage forms such as oral liquid, solid beverage, soft capsules, or tablets, suitable for daily conditioning in people with gastrointestinal dysfunction.

This invention proposes a traditional Chinese medicine compound for treating ankylosing spondylitis of the kidney-deficiency and damp-heat type accompanied by gastrointestinal dysfunction, along with its preparation method, belonging to the field of traditional Chinese medicine technology. The compound consists of Smilax glabra, Bletilla striata, Paris polyphylla, Geranium wilfordii, Dioscorea hypoglauca, Patrinia scabiosaefolia, Dipsacus asper, Drynaria fortunei, Pyrola rotundifolia, Clematis chinensis, Pheretima aspergillum, Lycopodium clavatum, Corydalis yanhusuo, Paeonia lactiflora, Atractylodes macrocephala (fried), Coix lacryma-jobi (raw), Aucklandia lappa, and Glycyrrhiza uralensis. This invention combines these herbs to achieve a synergistic effect, collectively clearing heat and dampness, strengthening the spleen and kidneys, and unblocking the meridians. The overall formula addresses both strengthening the body's foundation and eliminating pathogenic factors, ensuring unobstructed meridian flow and relieving arthralgia. This compound has the functions of clearing heat and dampness, strengthening the spleen and kidneys, and unblocking the meridians. It offers a short treatment course, rapid efficacy, low recurrence rate after cure, few side effects, and is inexpensive and convenient to use for treating ankylosing spondylitis with gastrointestinal dysfunction.

The invention relates to a preparation for treating acute plateau gastrointestinal dysfunction as well as a preparation method and application of the preparation, active ingredients in a pharmaceutical composition are extracted through a supercritical carbon dioxide fluid extraction technology on the basis of a formula for tonifying middle-Jiao and Qi, and a reagent or a reagent composition suitable for oral administration and / or patch is further prepared. The reagent or the reagent composition is suitable for gastrointestinal dysfunction caused by rapid plateau entry.

The application discloses strains for preventing and treating Parkinson's disease and compositions, applications and products thereof, and relates to the technical field of microorganisms.The application provides three strains of human milk origin, namely Lactobacillus helveticus LV-20, Lactobacillus plantarum LPP8 and Lactobacillus fermentum PL-15.The application also provides a composition capable of preventing and treating Parkinson's disease.The three strains can preferably prevent and treat Parkinson's disease.The composition can significantly improve motor dysfunction (such as static tremor, muscle rigidity, bradykinesia, posture balance and the like), reduce neuron damage, significantly reduce alpha-syn deposition, reverse sensory function degradation and cognitive impairment, relieve sleep disorders, inhibit neural inflammation and oxidative stress, reduce and repair intestinal barrier damage, relieve gastrointestinal dysfunction, improve constipation and regulate intestinal flora composition, and has a wide application prospect as a probiotic or synbiotic product for treating and preventing Parkinson's disease.

The invention discloses a Clostridium strain with a prevention or treatment effect on neurodegenerative brain diseases and an application of the Clostridium strain. The Clostridium strain provided by the invention has a neuroprotective effect, has a remarkable improvement effect in animal models of degenerative brain diseases such as Parkinson's disease and Alzheimer's disease, and has the effects of relieving dyskinesia and non-dyskinesia in the animal models of Parkinson's disease, including cognitive impairment, gastrointestinal dysfunction and the like; therefore, the strain can be effectively applied to foods and medicines for preventing or treating neurodegenerative brain diseases including Parkinson's disease, Alzheimer's disease, cognitive function impairment and the like.

The present disclosure provides methods related to treating or preventing gastrointestinal dysfunction in a subject in need thereof, which include the use of a diacylglycerol O-acyltransferase 1 (DGAT1) inhibitor. The disclosure also provides pharmaceutical compositions comprising a DGAT1 inhibitor, or pharmaceutically acceptable salts or esters thereof, useful for the treatments described herein.

The integrated therapeutic instrument comprises a therapeutic instrument body and an abdomen fixing piece connected with the therapeutic instrument body, an acupoint stimulation disc is arranged on one face of the therapeutic instrument body, a traditional Chinese medicine hot compress disc is arranged on the other face of the therapeutic instrument body, and the acupoint stimulation disc and the traditional Chinese medicine hot compress disc can turn over relative to the abdomen fixing piece. The acupoint stimulation disc comprises a driving mechanism and a massage disc, the driving mechanism is used for driving the massage disc to rotate, the traditional Chinese medicine hot compress disc comprises a heating piece and a traditional Chinese medicine bag which is matched with the heating piece and can be exposed out of the therapeutic apparatus body, and the therapeutic apparatus body can be further electrically connected with an application polar plate. After a patient wears the therapeutic apparatus main body through the abdomen fixing part, acupoint stimulation or traditional Chinese medicine hot compress function can be independently used for precise treatment, or alternate combined treatment is achieved by turning over and switching the treatment surface, use is convenient and easy, and the therapeutic apparatus has good clinical application value for promoting early rehabilitation of postoperative gastrointestinal dysfunction of the patient.

The invention discloses a Yifang polypeptide composition as well as a preparation method and application thereof, and belongs to the technical field of compositions. The beneficial formula polypeptide composition comprises a probiotic mixture, a prebiotic mixture and a polypeptide mixture. The composition capable of achieving a multi-target synergistic effect is constructed by scientifically compounding probiotics, prebiotics and various active polypeptides, so that the intestinal flora balance can be adjusted, the release of inflammatory factors can be inhibited through the biological activity of the polypeptides, the intestinal barrier function is repaired, and the intestinal health is improved. Therefore, the problems of gastrointestinal dysfunction, skin symptoms, immune disorder and the like caused by intestinal problems are fundamentally improved, and a more comprehensive and efficient solution is provided for solving complex intestinal health problems.

The invention provides a traditional Chinese medicine compound for treating kidney-deficiency damp-heat type ankylosing spondylitis with gastrointestinal dysfunction and clearing away heat, eliminating dampness and dredging governor meridian and a preparation method thereof, and belongs to the technical field of traditional Chinese medicines. The traditional Chinese medicine compound is prepared from rhizoma smilacis glabrae, rhizoma bletillae, rhizoma paridis, geranium wilfordii, rhizoma dioscoreae hypoglaucae, herba patriniae, teasel, rhizoma drynariae, herba pyrolae, radix clematidis, lumbricus, herba lycopodii, rhizoma corydalis, radix paeoniae rubra, roasted rhizoma atractylodis macrocephalae, raw semen coicis, costus root and liquorice. The medicines are combined, so that the effects of the medicines generate a synergistic effect, and the effects of clearing heat, eliminating dampness, tonifying spleen, tonifying kidney and dredging governor meridian are achieved together. The whole compatibility has the effects of consolidating root and eliminating evil, so that meridians and collaterals are dredged, and the arthralgia syndrome is solved. The traditional Chinese medicine compound has the functions of clearing heat, eliminating dampness, invigorating spleen, tonifying kidney and dredging governor meridian, and has the advantages of short treatment course, quick effect, low possibility of relapse after curing, small side effect, low price and convenience in use when being used for treating the ankylosing spondylitis accompanied by gastrointestinal dysfunction.