The invention discloses a Chinese traditional medicine and western medicine compound preparation for treating constipation and a preparation method thereof. The preparation comprises a Chinese traditional medicine component, a western medicine component and auxiliaries. The Chinese traditional medicine component is prepared from the following raw medicinal materials: camellia seeds, Chinese torreya, common perilla fruits, semen raphani, semen biotae, dessert almonds, plum kernels, wild semen juglandis, peach kernels, walnut kernels, fructus cannabis, snakegourd seeds, fructus amomi and fructus alpiniae oxyphyllae. The western medicine component is functional oligosaccharide. Aiming at cold constipation caused by deficiency of yang, endogenous coldness, stagnation of intestines and stomach, non-transportation of yang qi and non-distribution of body fluid, the Chinese traditional medicine and western medicine compound preparation disclosed by the invention has the effects of warming the kidney and assisting yang, warming spleen and stomach, tonifying kidney and securing essence and treating stranguria and activating blood so as to achieve the purpose of loosening the bowel to relieve constipation. In addition, the functional oligosaccharide selected can be used for improving vitamin metabolism so as to prevent bowel dysfunction and inhibit growth of harmful bacteria and pathogenic bacteria in the intestinal tract, thereby exerting the effects of improving the environment of the intestinal tract and protecting the intestinal tract. By combining Chinese traditional medicines which treat root causes and western medicines which regulate, the preparation disclosed by the invention fully exerts a curative effect and constipation cured is not easy to replase.