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Enteral nutrition preparation, and preparation method and applications thereof

An enteral nutrition preparation, marine biological technology, applied in application, food preparation, food science and other directions, can solve the problems of less animal protein and single protein, and achieve the effect of promoting digestion and absorption, easy digestion and absorption, and obvious effect

Active Publication Date: 2010-07-28
SOUTH CHINA SEA INST OF OCEANOLOGY - CHINESE ACAD OF SCI
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The outstanding problems of the marketed products are: their raw materials are mainly derived from terrestrial animal and plant extracts, and the nitrogen source used in most products is hydrolyzed vegetable protein and its derivatives. Animal protein is relatively small, and the source of protein is either single protein or protein , a mixture of peptides and amino acids
The above two patents are only designed from the perspective of nutritional supplements to formulate preparations, and do not fundamentally solve the gastrointestinal dysfunction commonly present in patients clinically.

Method used

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  • Enteral nutrition preparation, and preparation method and applications thereof
  • Enteral nutrition preparation, and preparation method and applications thereof
  • Enteral nutrition preparation, and preparation method and applications thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0026] Take edible oysters that meet the relevant seafood standards in my country, remove the shells and viscera, add twice the volume of drinking water to homogenize for 5 minutes, ultrasonicate for 10 minutes, and then add bromelain and papain to enzymatically hydrolyze. The amount of enzyme added is 1200U / g and 2400U respectively / g, the enzymolysis condition is pH6, the enzymolysis time is 4h, and the enzymolysis temperature is 60°C. After the reaction is over, the enzyme is extinguished at 100°C for 10 minutes, centrifuged at high speed for 15 minutes, and 1% of activated carbon is added to debitterize, deodorize and decolorize, and then use 200 mesh nylon sieve, and the filtrate was spray-dried to obtain 5 g of oyster protein peptide powder.

[0027] Purchased 13g of soybean peptide from Heze Zhongshi Peptidehao Biological Products Factory, purchased 1g of seawater spirulina powder from the South China Sea Institute of Oceanology, Chinese Academy of Sciences, purchased micr...

Embodiment 2

[0030] Take the edible cod that meets the relevant seafood consumption standards of our country, remove the viscera, add three times the volume of drinking water to homogenate for 5 minutes, and ultrasonicate for 10 minutes. First, add neutral protease for enzymatic hydrolysis. The enzymatic hydrolysis time was 3 hours, then the pH was adjusted to 9, and alkaline protease was added for enzymolysis, the amount of enzyme added was 800U / g, the enzymatic hydrolysis time was 3 hours, and the enzymatic hydrolysis temperature was kept at 55°C. After the reaction was completed, the enzyme was inactivated at 100°C for 10 minutes, and then centrifuged at high speed for 20 minutes , add activated carbon 1%, carry out debitterness, deodorization, decolorization, then filter with 200 mesh nylon sieves, and the filtrate is spray-dried to obtain 18g of fish protein peptide powder.

[0031] Purchased 3g of soybean peptide powder from Linyishan Biological Products Co., Ltd., purchased 1g of sea...

Embodiment 3

[0034] Effects of special enteral nutrition preparations for patients with gastrointestinal dysfunction on intestinal function in mice:

[0035] 1. Experimental animals and grouping

[0036] SPF grade BALB / C mice, male, weighing 18-22g. 10 rats in each group were randomly divided into 5 groups, in which the negative control group was fed with normal saline, the positive control group was fed with imported enteral nutrition preparation Pepi-2000, and the low-dose group (0.04g / g·bw) , middle dose group (0.08g / g·bw) and high dose group (0.16g / g·bw), the special enteral nutrition preparation for patients with gastrointestinal dysfunction.

[0037] 2. Effects of enteral nutrition preparations on body weight and food utilization coefficient of mice

[0038] According to the dose of 0.1ml / 10g, the nutrient solution of each group of mice was gavaged every day for 10 consecutive days. The mice were fed in a single cage during gavage, their food intake, water intake, and wet stool we...

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Abstract

The invention discloses an enteral nutrition preparation, and a preparation method and applications thereof. The enteral nutrition preparation according to the invention contains the following ingredients by mass percent: 3-20% of marine life protein peptide powder, 1-3% of seawater spirulina powder, 3-5% of fruit and vegetable powder, 3-15% of soybean peptide powder, 2-3% of corn oil, 1-2% of fish oil and 55-75% of maltodextrin. The enteral nutrition preparation according to the invention has good dissolubility as homogeneous solid powder and is homogeneous suspension after being dissolved, and the enteral nutrition preparation also has complete nutrients, easy for digestion, high in content of minerals and vitamins and rich in unsaturated fatty acids such as EPA and DHA, etc., can be used as nutritive support for patients suffering from gastrointestinal dysfunction, is significant to the recovery of body and gastrointestinal functions of the patients suffering from gastrointestinal dysfunction, and can also promote digestion and prominently enhance immunity. The enteral nutrition preparation according to the invention has the advantages of low production cost and being capable of saving energy and enhancing the utilization rate of raw material obviously.

Description

technical field [0001] The invention relates to the field of food production, in particular to an enteral nutrition preparation specially used for patients with gastrointestinal dysfunction and its preparation method and application. Background technique [0002] The gastrointestinal tract is the place where nutrients are digested and absorbed. Impairment of the motility, digestion and absorption functions of the gastrointestinal tract will cause malnutrition in the human body and further damage the digestion and absorption functions. In the treatment of gastrointestinal diseases, in addition to treating the cause, how to supplement nutrition to adapt to the function of the gastrointestinal tract and promote its recovery is an important part of the treatment. Scientific research and medical practice have shown that enteral nutrition is beneficial to the treatment of a variety of primary gastrointestinal diseases, because the nutrients in enteral nutrition are complete, eleme...

Claims

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Application Information

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IPC IPC(8): A23L1/305A23L33/18
Inventor 孙恢礼蔡冰娜吴园涛陈华张偲万鹏孙小钰
Owner SOUTH CHINA SEA INST OF OCEANOLOGY - CHINESE ACAD OF SCI
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