34results about How to "Increase the push rate" patented technology

The invention discloses lactobacillus paracasei CCFM1069 and an application thereof. The lactobacillus paracasei CCFM1069 can bear stomach intestine environment of human bodies, notably increase watercontent of excrement and urine, increase the propelling rate of small intestines, shorten the time of discharging a first granule of black stool, reduce the content of peptide YY in serum, raise thelevel of 5-hydroxytryptamine in colon tissue, raise the level of nerve nutrition factors 3 in the colon tissue, reduce Aqp4 genetic transcription level in the colon tissue, increase the number of Cajal interstitial cells in the colon tissue, and increase the content of short chain fatty acids in intestinal tracts; and the lactobacillus paracasei CCFM1069 has high adsorption capacity on pentadecafluorooctanoic acid, has the capacity of relieving PFOA toxicity and has quite good application prospects.

The invention discloses a lactobacillus fermentum Lee working fermenting agent product and application thereof to prevent constipation and keep healthy. Lactobacillus fermentum Lee is preserved in China Center for Type Culture Collection with the preservation number of CCTCCM2013512. Lactobacillus fermentum Lee is capable of normally growing in human intestinal tracts. Mouse in-vivo tests show that lactobacillus fermentum Lee is capable of alleviating the mouse body weight mitigating trend caused by constipation, accelerating melaena discharging time, improving intestinal propulsive rate, increasing levels of MTL, Gas, ET, AchE, SP and VIP in serum to different degrees, reducing SS factor level, increasing food intake and water intake, and reducing the decrease trend of defecation amount, defecation particle quantity and water content in faeces, gives play to effects similar to that of constipation-treating medicines, and shows certain constipation prevention effect. The optimum usage dosage is 1.0*10<9> CFU for per kg body weight.

The invention discloses Lactobacillus fermentum suo for adjusting intestinal tract motion and preventing constipation and a use thereof. The Lactobacillus fermentum suo has a preservation number of CCTCC NO: M2013511, has strong acid resistance, has a survival rate of 92.46+ / -4.06% after being arranged in an artificial gastric juice with a pH value of 3.0 for 3h, can slowly grow in cholate with a concentration of 1.0%, has a growth rate 17.36+ / -1.19% that of cholate-free culture, has cell hydrophobicity of 68.44+ / -2.48% and can normally grow in the human intestinal tract. Lactobacillus fermentum suo can relieve constipation-caused mouse weight reduction, reduce tarry stool excretion time, improve a small intestine propulsion rate, improve serum MTL, Gas, ET, AchE, SP and VIP factor levels to different degrees, reduce a SS factor, improve food intake and water intake, relieve reduction of a stool excretion mount, the number of stool particles and stool water content and can produce a certain constipation prevention effect similar to those of constipation treatment drugs.

The invention discloses Lactobacillus fermentum zhao capable of regulating intestinal movement and preventing constipation and application thereof, wherein the preservation number of the Lactobacillus fermentum zhao is CCTCCM2013513. The strain has higher acid resistance, has a survival rate reaching 85.12% plus / minus 5.18% after staying in pH3.0 artificial gastric juice for 3 h, can grow slowly in cholate with the concentration of 1.0% and has a growth efficiency reaching 18.33% plus / minus 0.52% of that of cholate-free culture. The hydrophobicity of Lactobacillus fermentum zhao cells is up to 70.80% plus / minus 0.61%. The Lactobacillus fermentum zhao can grow normally in human intestinal tracts. In-vivo tests using mice show that the Lactobacillus fermentum zhao can reduce the weight reduction tendency of the mice, shorten the time of defecation of dark stool, improve the peristalsis of small intestines, increase MTL, Gas, ET, AchE, SP and VIP factors to different extents, reduce SS factors, increase food consumption and water consumption, reduce the tendency that stool amount, stool pieces and stool water content decline, play an effect similar to that of a constipation medicine and show a certain constipation prevention effect.

The invention discloses a lactobacillus fermentum Lee working leavening agent product and constipation-prevention and health application thereof. The preservation number of lactobacillus fermentum Lee in China Center for Type Culture Collection is CCTCCM 2013512. The lactobacillus fermentum Lee can normally grow in intestinal tracts of human bodies. A mouse in vivo test further shows that the lactobacillus fermentum Lee can be used for retarding a mouse weight-reducing tendency caused by constipation; melena defecation time is accelerated and the small intestine propelling rate is improved; levels of MTL, Gas, ET, AchE, SP and VIP factors of blood serum can be increased to different extents, and SS factors are reduced; the food intake and the water drinking amount are increased; the tendency that defecation amount, the defecation grain quantity, and the moisture content of excrement decline are reduced; and the effect similar with constipation drugs is realized and a certain constipation-prevention effect is represented. The optimal use dosage is 1.0*10<9>CFU per kilogram of weight.

The invention discloses a system and method for collecting, searching, and analyzing an offline log. A push apparatus acquires a log on a node server, and pushes the log to a central server in real time. A monitoring apparatus monitors a general log list on the central server, and writes a path and category label information of a changed log file into a message queue. A relocating apparatus reads information which comprises information of the changed log file from the message queue, and relocates contents of the changed log file in a file corresponding to the changed log file in classification. A log collection and dividing apparatus divides a read file, and sends information after the division to a log storing and searching apparatus. The log storing and searching apparatus stores received information and performs classification indexing on received information. A data presentation apparatus presents found data. According to the system and method for collecting, searching, and analyzing an offline log provided by the invention, real-time collection, analysis and data presentation of offline logs of different regions are realized, and a problem processing time is saved.

The invention discloses lactobacillus rhamnosus CCFM1068 and application thereof.Thelactobacillus rhamnosus CCFM1068 can rapidly colonize in an intestinal tract, the water content of feces issignificantly increased, the intestinal propulsive rate is increased, defecation time of a first black stool is shortened, the content of peptide YYin serum is down-regulated, the level of5-hydroxytryptamine in colon tissuesis up-regulated, the level of neurotrophin-3 in thecolon tissues is up-regulated, the level of brain-derived neurotrophic factorsin thecolon tissues is up-regulated, and the level of Aqp4 gene transcriptionin thecolon tissues is up-regulated. In addition, the lactobacillus rhamnosus CCFM1068has a strong adsorption capacity for perfluorooctanoic acid and the ability to alleviate thetoxicity of PFOA. The lactobacillus rhamnosus CCFM1068 can well tolerate simulated gastrointestinal fluid, be used for preparing pharmaceutical compositions and fermented foods for relieving constipation and PFOA toxicity, and has a very broad application prospect.

The invention discloses use of one or more cannabinoid compounds or medicinal salts thereof to preparation of a pharmaceutical composition for treating irritable bowel syndrome. The invention furtherprovides a composition for treating irritable bowel syndrome. The composition comprises: 1) one or more cannabinoid compounds or medicinal salts thereof, and 2) one or more pharmaceutically acceptablecarriers or excipients.

The present invention discloses a film cutting and pulling method suitable for material packaging, and relates to the technical field of material packing techniques. The film cutting and pulling method comprises cutting a packaging film in a transportation process of the packaging film. In comparison with the conventional packaging methods, film cutting time is saved, and the packaging speed is thus raised. When the method is used for packaging materials of different specifications, the position of a film cutting mechanism does not need to be adjusted, the length of the packaging film only needs to be set in the system, and thus precision cutting of the packaging film can be carried out; and during packaging of materials of different specifications, time for adjusting machinery equipment is saved, and thus the efficiency of the whole packaging process is raised.

The invention discloses a lactobacillus casei strain Qian (CCTCC No. M2013514) working leavening agent product and an intestinal tract regulating health use thereof. The lactobacillus casei strain Qian working leavening agent product and a downstream product thereof are relatively strong in acid resistance, are 62.51+ / -7.35% in survival rate after being treated for 3 hours in artificial gastric juice with pH of 3.0, and are capable of slowly growing in 1.0% cholate, wherein the growth efficiency is 7.86+ / -0.45% that in non-cholate cultivation; the hydrophobic property of lactobacillus casei strain Qian cells is up to 51.30+ / -4.28%, and the lactobacillus casei strain Qian working leavening agent product normally grows in human intestinal tract. The lactobacillus casei strain Qian working leavening agent product can be used for slowing down mouse weight reducing trend caused by constipation, shortening dark stool defecating time, increasing a small intestine advance rate, reducing the gene expression level of mouse TRPV1. NOS, reducing the defecation quantity, and reducing defecation granule number and excrement moisture content reducing trend, achieves similar effects of constipation drugs and shows a certain constipation prevention effect.

The present invention discloses a pure Chinese medicine preparation for curing gastrointestinal type summer-heat and dampness common cold and its preparation method. Said invention adopts molecular distillation and supercritical CO2 fluid extraction equipment to extract the effective active substances of agastache / patchouli, magnolia bark, atractylodes root and dried ginger, after the agastache / patchouli extract, magnolia bark extract, atractylodes root extract and dried ginger extract are mixed according to a certain ratio, the medicinal vegetable oil auxiliary material is added, then they are made into the soft capsule by means of drum granule-pressing machine.

The invention discloses a lactobacillus casei strain Qian working stock culture product and an intestinal tract regulation dietary therapy funtion thereof. The lactobacillus casei strain Qian working stock culture product and downstream products thereof are stronger in acid-resistance, after being processed in artificial gastric juice of PH 3.0 for 3 hours, the survival rate of the products reaches 62.51+ / -7.35%, can grow slowly in 1.0% cholate with the production efficiency being 7.86+ / -0.45% of no cholate culture, hydrophobicity of lactobacillus casei strain Qian cells reaches 51.30+ / -4.28%, and the lactobacillus casei strain Qian cells can grow normally in the intestinal tract of human beings; the weight losing tendency of mice caused by constipation can be alleviated, the dark stool defecating time is shortened, the small intestine advance rate is improved, the TRRV1,NOS gene expression level of mice is lowered, and the tendency that defecating amount, the defecating particles and faeces water content are decreased is lowered, so that the lactobacillus casei strain Qian working stock culture product has the function similar to that of constipation medicine, and shows certain constipation prevention effect.

The invention discloses bifidobacterium breve capable of down-regulating IL-17 and relieving constipation and application of the bifidobacterium breve, and belongs to the field of microorganisms. The Bifidobacterium breve (B.breve) CCFM1260 provided by the invention can effectively relieve the first black stool time, the intestinal tract propulsion rate and the water content of stool of a constipation mouse, and has the effect of obviously improving the apparent pathological indexes of constipation; excellent benzopyrene adsorption capability is realized; in the detection of inflammation indexes, the bifidobacterium breve has a remarkable down-regulation effect on proinflammatory factors IL-17 and IL-1beta, and is more suitable for constipation patients accompanied by intestinal inflammation.

The invention belongs to the field of medicine, and relates to medical application of a composition. In order to solve the problem of constipation caused by taking an analgesic by a cancer patient, the invention provides the application of the composition in preparation of medicines for preventing and treating constipation. Mouse small intestine propulsion test results of pharmacodynamic embodiments show that the composition provided by the invention can significantly improve the small intestine carbon juice propulsion rate of mice; and mouse defecation test results show that the composition provided by the invention can significantly shorten the first defecation time of mice and increase the defecation times. Clinical results show that the effective components in the composition can playa significant synergistic effect, can significantly reduce the recurrence rate, and has important significance in solving the constipation problem of cancer patients.

The invention discloses a lactobacillus fermentum Lee working leavening agent product and constipation-prevention and health application thereof. The preservation number of lactobacillus fermentum Lee in China Center for Type Culture Collection is CCTCCM 2013512. The lactobacillus fermentum Lee can normally grow in intestinal tracts of human bodies. A mouse in vivo test further shows that the lactobacillus fermentum Lee can be used for retarding a mouse weight-reducing tendency caused by constipation; melena defecation time is accelerated and the small intestine propelling rate is improved; levels of MTL, Gas, ET, AchE, SP and VIP factors of blood serum can be increased to different extents, and SS factors are reduced; the food intake and the water drinking amount are increased; the tendency that defecation amount, the defecation grain quantity, and the moisture content of excrement decline are reduced; and the effect similar with constipation drugs is realized and a certain constipation-prevention effect is represented. The optimal use dosage is 1.0*10<9>CFU per kilogram of weight.

The invention relates to an application of a raw rhubarb composition in bowel relaxing, qi regulating, and intestinal recovery. The raw rhubarb composition comprises, by weight, 8-10 parts of raw rhubarb, 4-6 parts of stir-fried immature bitter orange, 4-6 parts of officinal magnolia bark, 3-5 parts of swordlike atractylodes rhizome, 4-6 parts of tangerine peel, 4-6 parts of immature tangerine fruit, 4-6 parts of coked hawthorn fruit, and 4-6 parts of medicated leaven. With bowel relaxing and qi regulating functions, rat small intestine and colon movements can be enhanced, and defaecation can be accelerated. An in-vitro experiment result is completely opposite to an in-vivo experiment. The result of the in-vitro experiment shows that with the bowel relaxing and qi regulating functions, normal rat ileum and colon movements can be inhibited, and the excitation effect of acetylcholine upon small intestine can be significantly inhibited.

The invention discloses a Lactobacillus fermentum strain Zhao which can regulate intestinal motility and prevent constipation. The preservation number is CCTCC NO: M 2013513 and its application. After 3 hours in gastric juice, the survival rate reached 85.12±5.18%. It can grow slowly under 1.0% concentration of bile salt, and the growth efficiency reaches 18.33±0.52 of culture without bile salt. The hydrophobicity of Lactobacillus fermentum strain Zhao cells also reached 70.80±0.61 %. Can grow normally in the human intestine. Experiments in mice also showed that Lactobacillus fermentum strain Zhao can slow down the weight loss trend of mice caused by constipation, accelerate the time of black stool discharge, improve the propulsion rate of the small intestine, and increase serum MTL, Gas, ET, The levels of AchE, SP and VIP factors, decreased SS factors, increased food intake and water intake, decreased defecation volume, the number of defecated particles and the trend of decreasing water content in feces, played a similar role to constipation drugs, showing a certain preventive effect on constipation .

The invention discloses a traditional Chinese medicine compound composition for treating refractory gastroesophageal reflux. The traditional Chinese medicine compound composition is prepared from the following components in parts by weight: 10-20 parts of inula flower, 10-20 parts of processed rhizoma pinelliae, 10-20 parts of processed rhizoma cyperi, 4-14 parts of caulis perllae, 10-20 parts of raw folium eriobotryae, 10-20 parts of pericarpium citri reticulatae, 10-20 parts of poria cocos, 20-40 parts of cuttlebone and 20-40 parts of fried semen raphani. The traditional Chinese medicine compound composition for treating refractory gastroesophageal reflux provided by the invention has an anti-inflammatory effect, can improve the gastric emptying rate of rabbits, improve the small intestine peristalsis of the rabbits and improve the small intestine propulsion rate, can reduce the expression of inflammatory factors in gastric tissues, has no adverse reaction and no obvious toxic or side effect, and is safe and effective.

The invention discloses an enteral nutrition preparation, and a preparation method and applications thereof. The enteral nutrition preparation according to the invention contains the following ingredients by mass percent: 3-20% of marine life protein peptide powder, 1-3% of seawater spirulina powder, 3-5% of fruit and vegetable powder, 3-15% of soybean peptide powder, 2-3% of corn oil, 1-2% of fish oil and 55-75% of maltodextrin. The enteral nutrition preparation according to the invention has good dissolubility as homogeneous solid powder and is homogeneous suspension after being dissolved, and the enteral nutrition preparation also has complete nutrients, easy for digestion, high in content of minerals and vitamins and rich in unsaturated fatty acids such as EPA and DHA, etc., can be used as nutritive support for patients suffering from gastrointestinal dysfunction, is significant to the recovery of body and gastrointestinal functions of the patients suffering from gastrointestinal dysfunction, and can also promote digestion and prominently enhance immunity. The enteral nutrition preparation according to the invention has the advantages of low production cost and being capable of saving energy and enhancing the utilization rate of raw material obviously.

The invention relates to a traditional Chinese medicine composition and application of the composition in the treatment of infant anorexia and particularly relates to a traditional Chinese medicine extract. The traditional Chinese medicine composition is characterized by containing components A, B and C, wherein the component A is water-refluxed extract of semen euryales, cored lotus seeds and rhizoma alismatis; the component B is absolute ethyl alcohol-refluxed extract of medicated leaven, chickens gizzard membrane and haws; and the component C is a 50% ethanol-refluxed extract of rhizoma atractylodis macrocephalae, radix paeoniae alba, Chinese yams, peeled poria cocos, liquorice, fructus quisqualis and pericarpium citri reticulatae.

The invention discloses a bifidobacteria bifidum for relieving constipation and regulating intestinal flora disorder and its application, belonging to the field of microorganisms. The bifidobacteria bifidum provided by the invention can significantly improve the water content of the feces and the propulsion rate of the small intestine, reduce the time of the first black stool in the constipated mice, and can obviously improve the apparent pathological indicators of constipation; in the detection of physiological indicators, the two Bifidobacterium can also increase the content of motilin, reduce the content of somatostatin, and fundamentally affect intestinal peristalsis; Bifidobacterium can regulate the abundance of important microorganisms in the intestine and maintain intestinal homeostasis; two Bifidobacterium CCFM1166 is better than GDMCC NO: 60940 to increase the content of MTL in serum, reduce the content of SS in serum, and has a more significant effect on promoting small intestinal peristalsis. Therefore, in the future, more personalized medicine can be used for patients with constipation. The treatment plan has very considerable application prospects.

The invention discloses Lactobacillus paracasei CCFM1069 and its application. Lactobacillus paracasei CCFM1069 can tolerate the gastrointestinal environment of human body, significantly improve the water content of feces, improve the propulsion rate of small intestine, shorten the time for the first black stool, and down-regulate casein in serum. Tyrosin content, up-regulation of serotonin level in colon tissue, up-regulation of neurotrophic factor 3 level in colon tissue, down-regulation of Aqp4 gene transcription level in colon tissue, increase of the number of interstitial cells of Cajal in colon tissue and increase of short-chain fatty acid content in intestine content; the Lactobacillus paracasei CCFM1069 has a strong adsorption capacity for perfluorooctanoic acid, has the ability to alleviate the toxicity of PFOA, and has a very wide application prospect.

The present invention discloses a pure Chinese medicine preparation for curing gastrointestinal type summer-heat and dampness common cold and its preparation method. Said invention adopts molecular distillation and supercritical CO2 fluid extraction equipment to extract the effective active substances of agastache / patchouli, magnolia bark, atractylodes root and dried ginger, after the agastache / patchouli extract, magnolia bark extract, atractylodes root extract and dried ginger extract are mixed according to a certain ratio, the medicinal vegetable oil auxiliary material is added, then they are made into the soft capsule by means of drum granule-pressing machine.

The invention discloses monascus bean dreg vinegar and a preparation method thereof, and belongs to the technical field of vinegar brewing. Bean dregs and monascus vinegar are combined for the first time, namely the bean dregs serving as raw materials are used for preparing distiller's yeasts and vinegar fermented grains; meanwhile the monascus bean dreg vinegar is prepared by taking the bean dregs as the main raw materials through the processes of cooking and liquefying, performing alcoholic fermentation, performing acetic acid fermentation, ageing, blending and the like. Cellulose and sugarin the bean dregs are subjected to microbial fermentation, particularly under the action of monascus, aspergillus niger, acetic acid bacteria and lactic acid bacteria, the flavor, the color and the nutritional value of the monascus bean dreg vinegar are increased; meanwhile the effects of promoting gastrointestinal motility as well as invigorating stomach and promoting digestion are achieved; in addition, an important function of promoting effective utilization of bean dreg resources is achieved.

The invention discloses a lactobacillus fermentum Lee working fermenting agent product and application thereof to prevent constipation and keep healthy. Lactobacillus fermentum Lee is preserved in China Center for Type Culture Collection with the preservation number of CCTCCM2013512. Lactobacillus fermentum Lee is capable of normally growing in human intestinal tracts. Mouse in-vivo tests show that lactobacillus fermentum Lee is capable of alleviating the mouse body weight mitigating trend caused by constipation, accelerating melaena discharging time, improving intestinal propulsive rate, increasing levels of MTL, Gas, ET, AchE, SP and VIP in serum to different degrees, reducing SS factor level, increasing food intake and water intake, and reducing the decrease trend of defecation amount, defecation particle quantity and water content in faeces, gives play to effects similar to that of constipation-treating medicines, and shows certain constipation prevention effect. The optimum usage dosage is 1.0*10<9> CFU for per kg body weight.

The invention discloses a working starter product of Lactobacillus casei strain Qian (CCTCC No. M2013514) and its use for intestinal regulation and health care. .0 artificial gastric juice under treatment for 3 hours, the survival rate reached 62.51±7.35%. It can grow slowly under 1.0% concentration of bile salt, and the growth efficiency reaches 7.86±0.45% of the culture without bile salt. The hydrophobicity of Lactobacillus casei strain Qian cells It also reached 51.30±4.28%, and it grows normally in the human intestine; it can slow down the weight loss trend of mice caused by constipation, accelerate the time of black stool, improve the small intestinal propulsion rate, and lower the gene expression level of TRPV1 and NOS in mice , to reduce the defecation volume, the number of defecation particles, and the trend of decreasing the water content of feces, which has a similar effect to constipation drugs, showing a certain effect of preventing constipation.

Chronic constipation is a common disease of the digestive system, and the prevalence rate of chronic constipation around the world is 0.7 to 79%. The invention discloses a pharmaceutical composition for treating chronic constipation. The pharmaceutical composition comprises 4-12 mg of an active medicinal ingredient and other pharmaceutically acceptable carriers, diluents and excipients. The pharmaceutical composition of the invention can increase the number of ILL, repair the function of ILL and achieve the purposes of restoring colonic functions, improving the propulsion rate of small intestine and alleviating the symptoms of constipation.

The present invention discloses a film cutting and pulling method suitable for material packaging, and relates to the technical field of material packing techniques. The film cutting and pulling method comprises cutting a packaging film in a transportation process of the packaging film. In comparison with the conventional packaging methods, film cutting time is saved, and the packaging speed is thus raised. When the method is used for packaging materials of different specifications, the position of a film cutting mechanism does not need to be adjusted, the length of the packaging film only needs to be set in the system, and thus precision cutting of the packaging film can be carried out; and during packaging of materials of different specifications, time for adjusting machinery equipment is saved, and thus the efficiency of the whole packaging process is raised.

The invention discloses a working starter product of Lactobacillus casei strain Qian (CCTCC No. M2013514) and its use for intestinal regulation diet therapy. .0 artificial gastric juice under treatment for 3 hours, the survival rate reached 62.51±7.35%. It can grow slowly under 1.0% concentration of bile salt, and the growth efficiency reaches 7.86±0.45% of the culture without bile salt. The hydrophobicity of Lactobacillus casei strain Qian cells It also reached 51.30±4.28%, and it grows normally in the human intestine; it can slow down the weight loss trend of mice caused by constipation, accelerate the time of black stool, improve the small intestinal propulsion rate, and lower the gene expression level of TRPV1 and NOS in mice , to reduce the defecation volume, the number of defecation particles, and the trend of decreasing the water content of feces, which has a similar effect to constipation drugs, showing a certain effect of preventing constipation.