346 results about "Bifidobacterium animalis" patented technology

The invention discloses bifidobacterium longum and applications thereof, and belongs to the technical field of microorganisms. The bifidobacterium longum is deposited in the China General Microbiological Culture Collection Center in Institute of Microbiology, Chinese Academy of Sciences at number 3, No.1 yard, Beichenxi road, Chaoyang district, Beijing on December 7, 2017, and the accession numberis CGMCC NO.15032. The bifidobacterium longum has good growth, acid production, and acid resistant properties, and high adhesive capacity, can significantly increase the water content of faeces and the pushing rate of small intestine of mice with constipation, shortens the first black stool evacuation time, relieves inflammation of colonic mucosas, and regulates contents of gastrointestinal peptides related to constipation in serum. A constipation relieving effect of the bifidobacterium longum is equivalent to that of bifidobacterium animalis BB12, but an effect of the bifidobacterium longumon the pushing rate of small intestine is superior to those of bifidobacterium animalis BB12 and phenolphthalein. Accordingly, the bifidobacterium longum strain CCFM760 can be widely applied in various foods or medicine matrixes.

The invention provides a method for preparing a traditional Chinese medicine fruit and vegetable enzyme beverage, and relates to the food field. The method comprises the steps: mixing a fruit and vegetable mixture with rock candy according to the mass ratio of 3:(0.5-1.5), placing the mixture in a fermentation tank, and in a sealed state and under a condition of the temperature of 2-30 DEG C, fermenting for 160-200 days, to obtain a fruit and vegetable fermented liquid; mixing the fruit and vegetable fermented liquid with a traditional Chinese medicine decoction liquid, inoculating with one or two or more of lactobacillus delbrueckii subsp.bulgaricus, lactobacillus plantarum subsp.plantarum, yeast and bifidobacterium animalis, and in a sealed state and at the temperature of 35-40 DEG C, fermenting for 3-8 days, to obtain the traditional Chinese medicine fruit and vegetable enzyme beverage. The medicine and food homology and mutual harmony and complementation effects are achieved; the obtained traditional Chinese medicine fruit and vegetable enzyme beverage has the advantages of high total phenol content, high DPPH(.) scavenging rate and high SOD enzyme activity, shows strong antioxidant capacity, can improve the human body gastrointestinal health-care functions, and can be used as a daily drinking health drink.

The invention is applicable within the food and pharmaceutical industry. More specifically, it relates to a novel strain of the species Bifidobacterium animalis subsp. lactis CECT 8145, the cell components, metabolites and secreted molecules thereof, which, incorporated into food and/or pharmaceutical formulations, can be used in the treatment and/or prevention of excess weight and obesity and related diseases such as metabolic syndrome, hypertension, glycemia, inflammation, type 2 diabetes, cardiovascular diseases, hypercholesterolemia, hormonal alterations, infertility, etc.

The invention relates to a high-density culture method of bifidobacterium lactis V9 and a preparation method of a freeze-dried powder of the bifidobacterium lactis V9, and belongs to the field of probiotics fermentation. The bifidobacterium lactis V9 (Bifidobacterium animalis subsp.lactis V9) is acid-resistant and cholate-resistant probiotics which are separated from the intestinal tract of a healthy Mongolian child, and the collection number of the bifidobacterium lactis V9 is CGMCC No.5470. High-density fermentation of the bacteria of the bifidobacterium lactis V9 is realized under the control of an optimized culture medium and optimized fermentation conditions; the viable count in a fermentation liquor can be more than 2.0*10<10>cfu/ml, and the viable count in the freeze-dried powder of the bifidobacterium lactis prepared by using the fermentation liquor can be more than 6.0*10<11>cfu/g, and therefore, the freeze-dried powder of the bifidobacterium lactis can be applied to a probiotic leavening agent or a probiotic preparation.

The invention discloses a compound probiotic agent for improving immunity of dogs and reducing incidence of diarrhea as well as a preparation method and application thereof, and belongs to the field of the compound probiotic agent. The compound probiotic agent is prepared by mixing and compounding a lactobacillus plantarum KT-Lp9 microbial agent, a lactobacillus casei zhang microbial agent, a lactobacillus plantarum P-8 microbial agent, a bifidobacterium animalis subsp. lactis V9 microbial agent and a dilution carrier, wherein the quantity of viable bacteria of the four kinds of microbial agents is more than or equal to 2*10<11>CFU/g. The compound probiotic agent with different contents of viable bacteria only can be applied to 96 dogs at different ages for 60 days, so that the immunity of the test dogs can be improved, and the incidence of diarrhea and the sickness degree are reduced. Main representations are that the feed intake and growth rate of the dogs are increased, leukocyte counts, lymphocytes counts and neutrophil counts in blood are controlled, and the contents of four immunologic factors including immune globulin G, interleukin 6, interferon alpha and tumor necrosis factor alpha in the blood can be increased; and meanwhile, the content of secretory immunoglobulin A (SigA) in excrement is increased.

To provide a bacterium belonging to the genus Bifidobacterium which is excellent in a survival ability in the gastrointestinal tract, has an effect of inhibiting the cholesterol absorption in the intestinal tract, and is excellent in lipid metabolism ameliorating effects including decreasing the blood cholesterol level and the like, and shows a high survival rate after storage, and a cholesterol absorption inhibitor using the same. The invention provides a cholesterol absorption inhibitor containing, as an active ingredient, at least one microorganism selected from Bifidobacterium animalis subsp. animalis YIT 10394, Bifidobacterium animalis subsp. lactis JCM 1253, Bifidobacterium animalis subsp. lactis JCM 7117, and Bifidobacterium pseudolongum subsp. globosum.

The invention discloses compound probiotics capable of relieving ulcerative colitis, a preparation method and application thereof, and relates to the technical field of microorganisms. The compound probiotics are characterized by comprising Bifidobacterium longum BL21, Bifidobacterium animalis subsp.lactis BLa80 and Lactobacillus casei LC89. The preparation method comprises the following steps of: respectively preparing freeze-dried powder of the Bifidobacterium longum BL21, the Bifidobacterium animalis subsp.lactis BLa80 and the Lactobacillus casei LC89; and uniformly mixing the three freeze-dried powder in proportion to prepare the compound probiotics. The compound probiotics provided by the invention can prevent and/or treat ulcerative colitis, and have a great application prospect in preparation of products (such as solid beverages) for preventing and/or treating ulcerative colitis.

The invention provides lactobacillus casei, bifidobacterium animalis, lactobacrillus plantarum and bacillus subtilis for solid fermentation of probiotics in the field of feed additives. The lactobacillus casei, bifidobacterium animalis, lactobacrillus plantarum and bacillus subtilis are characterized in that the bacillus subtilis HM-66, the lactobacillus casei F-08, the lactobacillus plantarum HM-20 and the bifidobacterium animalis V9 are all probiotics, and are preserved in the general microbiological culture collection center of the Chinese microbiological culture collection management committee with the preservation numbers of CGMCC No.6733, CGMCC No.6735, CGMCC No.6744 and CGMCC No.5470 respectively; the preservation dates of the bacillus subtilis HM-66, the lactobacillus casei F-08 and the lactobacillus plantarum HM-20 are October 29th, 2012, and the preservation date of the bifidobacterium animalis V9 is November 18th, 2011. The invention further discloses an application method of the lactobacillus casei, bifidobacterium animalis, lactobacrillus plantarum and bacillus subtilis.

The invention discloses a probiotic composition for relieving anxiety or depression and an application thereof. The probiotic composition comprises prebiotics, a K-KLJ probiotic combination and functional substances. The K-KLJ probiotic composition contains at least one of lactobacillus plantarum, lactobacillus reuteri, lactobacillus casei, and lactobacillus helveticus, or also contains at least one of lactobacillus rhamnosus, lactobacillus acidophilus, bifidobacterium animalis and bifidobacterium longum. The probiotic composition of the present invention can significantly increase quantity ofbeneficial intestinal flora, improve intestinal discomfort, and reduce chronic inflammation, thereby reducing unhealthy emotion, and preventing emotional diseases such as depression and anxiety. Moreover, according to the invention, the combination of probiotic strains, the prebiotics, the probiotic strains and the functional substances have effect of significant synergistic enhancement.

Provided is fragrant pig derived cholesterol-assimilating and oxygen-resistant bifidobacterium BZll. The fragrant pig derived cholesterol-assimilating and oxygen-resistant bifidobacterium BZll is Bifidobacterium animalis subsp.Lactis, the pure culture of the fragrant pig derived cholesterol-assimilating and oxygen-resistant bifidobacterium BZll is preserved at the China General Micro-biological Culture Collection Center (CGMCC), China Microbial Culture Preservation Management Committee, the address is Institute of Microbiology, Institution No.3 China Academy of Science, Western Beichen Road No.1 in Chaoyang District of Beijing in China, the postal code is 100101, the preservation number is CGMCC NO.10224, and the Bifidobacterium animalis subsp.Lactis BZll is called for short. The Bifidobacterium animalis subsp.Lactis BZll is high in cholesterol-assimilating capacity, acid resistance and cholate resistance, good in oxygen resisting performance, has probiotic property and can serve as probiotics to be added into a fermentative milk product to produce a functional food, bifidobacterium culture resources are enriched, and development of bifidobacterium health-care products is facilitated.

The invention provides composite probiotic lactobacillus powder as well as a preparation method and application thereof. The composite probiotic lactobacillus powder is prepared by compounding lactobacillus casei Zhang powder, bifidobacterium animalis V9 powder, lactobacillus plantarum P-8 powder, lactobacillus plantarum C2 powder, prebiotics and fruit and vegetable powder. The composite probioticlactobacillus powder has the remarkable protective effect on irritable bowel syndrome, oral infection and nasal infection, has the remarkable prevention effect on occurrence of upper respiratory infection, can improve gastrointestinal symptoms and adjust intestinal flora, and can improve the immunity of the organism.

The invention discloses a micro-ecological composition for improving constipation by targeting intestinal flora and a preparation of the micro-ecological composition. The micro-ecological compositioncomprises probiotics, prebiotics and medicinal and edible traditional Chinese medicines, wherein the probiotics are selected from at least one of bifidobacterium animalis, bifidobacterium adolescentis, bifidobacterium longum, bifidobacterium breve, lactobacillus rhamnosus, lactobacillus acidophilus, lactobacillus helveticus, lactobacillus plantarum, lactobacillus reuteri, lactobacillus paracasei and bacillus coagulans; the prebiotics are selected from at least one of stachyose, fructo-oligosaccharide, isomalto-oligosaccharide, galacto-oligosaccharide, inulin, resistant dextrin and xylooligosaccharide; and the medicinal and edible traditional Chinese medicines are selected from at least one of semen sesami nigri, semen cassiae, fructus cannabis, honey, semen lablab album, semen coicis, poria cocos and lotus leaves. The micro-ecological composition can effectively regulate intestinal tract micro-ecology in a targeted mode, and finally the purpose of improving constipation is achieved.

The invention provides a granulation-resisting lactic acid bacterium preparation and a preparation method thereof. The granulation-resisting lactic acid bacterium preparation comprises lactic acid bacterium; the lactic acid bacterium is one or a combination of more of enterococcus faecalis, enterococcus faecium, lactobacillus plantarum, lactobacillus acidophilus, lactobacillus lactis, lactobacillus buchneri, lactobacillus casei and bifidobacterium animalis; a viable count of the lactic acid bacterium reaches 1.0*10<10> to 1.0*10<11>CFU/g. According to the preparation method of the lactic acidbacterium preparation, provided by the invention, the tolerance of thalli is improved and the loss of bacterium activity in a processing process is avoided.

The invention belongs to the technical field of food processing, and relates to the technical field of probiotics nutrients, in particular to five-probiotic nutritive powder and a preparation method thereof. The five-probiotic nutritive powder provided by the invention comprises the following raw material components in parts by weight: 2-9 parts of lactobacillus reuteri, 3-9 parts of bifidobacterium lactis, 3-6 parts of bifidobacterium infantis, 2-8 parts of bifidobacterium animalis, 4-11 parts of lactobacillus rhamnosus, 18-38 parts of stachyose, 26-39 parts of fructo-oligosaccharide and 56-86 parts of maltodextrin. The formula of the five-probiotics nutritive powder disclosed by the invention is suitable for babies and middle-aged and old people to use, five-probiotics powder suitable for the babies and the middle-aged and old people to eat can be obtained, the internal environment of the intestinal tracts can be improved, probiotics in the intestinal tracts can be in a dominant position, the propagation and the growth of harmful funguses can be restrained, toxins are degraded, the immunity of the babies and the middle-aged and old people can be enhanced, and the health of human bodies can be promoted.

The invention discloses bifidobacterium animalis NX-6 and application thereof in preparation of lipid-lowering and weight-losing medicines, and belongs to the technical field of microorganisms. The preservation number of the bifidobacterium animalis NX-6 disclosed by the invention is CGMCC (China General Microbiological Culture Collection Center) No. 20114. The uninactivated and inactivated fermentation supernate, bacterial suspension and cell disrupted supernate of novel bifidobacterium animalis NX-6 show good effects of slowing down weight and body length increase, improving body mass index(BMI) and reducing fat area percentage on zebrafish, and have a potential weight losing effect; triglyceride (TG) and total cholesterol (TC) in a zebrafish hyperlipidemia model body can be obviously reduced, and a good hypolipidemic effect is shown. The novel bifidobacterium animalis NX-6 disclosed by the invention has a huge potential application prospect in the aspect of preparing medicines fortreating and/or preventing obesity and hyperlipidemia.

The invention discloses a bifidobacterium animalis and application thereof in preparing a bifidobacterium fermented beverage. The bifidobacterium animalis is bifidobacterium animalis 01, and has the preservation number of CGMCC 1353. The bifidobacterium animalis 01 with the preservation number of CGMCC 1353 can be used for preparing the bifidobacterium fermented beverage. The prepared yacon bifidobacterium fermented beverage has mild color (as shown in figure 1), good mouth feel, good flavor and longer shelf life, and is a health beverage with a good health-care effect.

The application provides compound probiotics powder for treating irritable bowel syndrome (IBS). The compound probiotics powder is prepared from lactobacillus casei Zhang, bifidobacterium animalis subsp. lactis V9 and lactobacillus plantarum P-8; the compound probiotics powder is obtained through optimizing, compounding and combining nutrient substances with different properties; the compound probiotics powder can regulate intestinal flora, effectively treats the IBS, can obviously improve symptoms, and reduces inflammatory responses, thereby solving the problems that existing compound probiotics lactobacillus powder is single in flora composition, low in viable count, and poor in probiotics safety, and is lacking in probiotics preparations which effectively treat the IBS; the compound probiotics powder has wide market prospects.

The invention discloses Bifidobacterium animalis with a bowel relaxing function and application and a preparation of the Bifidobacterium animalis. According to the Bifidobacterium animalis, Bifidobacterium lactis BB-11 is separated from an intestinal content of healthy and long-lived elderly people in Bama, Guangxi, the strain is carried on a spacecraft, finally, a Bifidobacterium animalis MN-Gupwith significantly improved oxygen resistance or significantly enhanced oxygen resisting capacity is screened by space mutagenesis, and evaluation of constipation model mice proves that the strain hasthe good bowel relaxing function and has broad application prospects in bowel relaxing drugs, health foods and foods.

The invention provides a repairing and soothing skin care product containing a postbiotic component and a preparation method thereof. The repairing and soothing skin care product comprises the following components in percentage by mass: 1-5% of the postbiotic component, 1-8% of grease, 3-5% of a skin conditioner, 9-15% of a humectant, 0.5-8% of a surfactant, 0.6-1.2% of a thickening agent and the balance being deionized water. The postbiotic component comprises an antibacterial substance and an active metabolite, has the effects of reconstructing skin cells, improving elastin and updating metabolism of a corium layer, and has an effect of promoting proliferation of cuticle cells, and the prepared skin care product can enhance skin elasticity and has obvious skin soothing and repairing effects. According to the invention, the postbiotic component is a mixed solution obtained by fermenting a variety of strains such as lactobacillus plantarum, lactobacillus casei, bifidobacterium lactis, bifidobacterium animalis and lactobacillus rhamnosus; compared with a postbiotic component obtained by single strain fermentation, the effect of eliminating wrinkles and enhancing skin elasticity is better, and the multi-dimensional skin problem can be solved.

The invention discloses a probiotics-containing breast milk-like formula milk powder for infants. Raw milk is used as a base material; according to nutrient differences of breast milk and raw milk, whey protein is added to adjust the ratio of whey protein to casein in a product to be close to 6:4; soybean oil is added to adjust deficiency of linoleic acid in milk fat, wherein linoleic acid accounts for about 12.8 percent of the total fat of the breast milk but only 2.2 percent of the total fat of raw milk; arachidonic acid (AA), docosahexaenoic acid (DHA), sialic acid (SA) and 3'-sialyllactose(3'-SL) are added to promote brain development of infants and improve memory and intelligence; and bifidobacterium lactis HN019, bifidobacterium animal Bb-12 and lactobacillus paracasei N1115 are added to regulate intestinal healthy development of infants. The invention also provides a preparation method of the milk powder. The milk powder is close to the nutrition index in the Chinese breast milk and is suitable for growth and development of infants in China.

The invention provides a composition for resisting helicobacter pylori and an application of the composition. Each 100g of the composition comprises the following active components according to the content: 5-20g of inactivated lactobacillus reuteri, 0.1-1g of inactivated lactobacillus paracasei, 1.5-25g of bifidobacterium animalis viable bacteria, 1.2-20g of lactobacillus rhamnosus, 5-10g of hippophae rhamnoides fruit powder, 0.1-1g of a broccoli seed aqueous extract, 20-30g of fructo-oligosaccharide and 10-70g of lacitiol. According to the composition, the inactivated lactobacillus reuteri,the inactivated lactobacillus paracasei, the hippophae rhamnoides fruit powder, the broccoli seed aqueous extract, the fructo-oligosaccharide and the lacitiol are prepared into a specific compositionformula together, and the formula not only can well prevent and treat bacterial infection of gastrointestinal tracts and bacterial infection of oral cavities, particularly concurrently has better mouth feel flavor, and is green and healthy due to no addition of seasonings of essence and the like.

The invention provides a probiotic composition and a preparation method and application thereof. The probiotic composition comprises raw materials of lactobacillus reuteri, lactobacillus acidophilus and bifidobacterium animalis, wherein the weight ratio of the lactobacillus reuteri to the lactobacillus acidophilus to the bifidobacterium animalis is (1.5-2.5):(0.5-1.5):(0.5-1.5). The colony forming units of the lactobacillus reuteri, the lactobacillus acidophilus or the bifidobacterium animalis in unit weight are the same. The lactobacillus reuteri is preserved in China Center for Type Culture Collection with the preservation number of 209138, and the lactobacillus acidophilus and/or the bifidobacterium animalis preserved in China General Microbiological Culture Collection Center with the preservation number of CGMCC 15210 are/is bifidobacterium animalis BB-115. The probiotic composition can relieve the symptom of slow transit constipation under the condition of low dosage, and can remarkably and effectively regulate gastrointestinal regulatory peptide indexes related to constipation, such as P substance (SP), gastrin (Gas) and vasoactive peptide (VIP).

The present invention discloses a probiotic composition for enhancing immunity and an application of the probiotic composition. The probiotic composition comprises prebiotics, a K-MYL probiotic combination and functional substances, and the K-MYL probiotic combination comprises at least one of lactobacillus casei, lactobacillus bulgaricus, saccharomyces boulardii, lactobacillus reuteri and bifidobacterium animalis, or further comprises at least one of lactobacillus rhamnosus, lactobacillus acidophilus and bifidobacterium longum. The probiotic composition can significantly increase the number of intestinal effective microbial communities, improve intestinal immune functions, improve expressions of intestinal immune factors, resist virus infection and shorten recovery time after the virus infection. Moreover, probiotic strain combinations, the prebiotics, probiotic strains and the functional substances have remarkable synergistic enhancement effects.

The invention belongs to the field of microbial fermentation application, and relates to a functional food produced by fermenting jujube, soybean meal, angelica sinensis, radix astragali and the likeby using probiotics and a preparation method of the functional food. The fermented food is prepared in the steps that the probiotics including lactobacillus plantarum, bifidobacterium animalis, bifidobacterium adolescentis, bacillus coagulans and lactobacillus paracasei are utilized to liquid state or solid state fermentation of the jujube, the soybean meal, angelica sinensis powder, radix astragali powder and the like. The fermented beverage and food preserve nutritive values of natural plants and have the nutrition and health care functions of probiotics fermented products, the taste is unique, the function is obvious, the functional food has an important adjustment effect on deficiency of Qi and blood and menoxenia of women, and the functional food has the functions of promoting blood circulation to arrest pain.