Probiotic composition for enhancing immunity and application of probiotic composition

A technology for enhancing immunity and probiotics, applied in applications, drug combinations, bacteria used in food preparation, etc., can solve the problem of insignificant effects on human health, lack of in-depth research on synergistic effects of probiotic strains and probiotic strains, and underestimation of the effects of probiotics and other issues, to achieve the effect of reducing the risk of influenza virus infection, enhancing the ability to resist virus infection, great social significance and economic value

Pending Publication Date: 2020-12-11
WUHAN KANGFUDE BIOTECH CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] However, most of the probiotic products currently on the market are only aimed at supplementing probiotics. There is no in-depth study of the relationship between the function of probiotic strains and the sub-health status of the human body and the synergy between probiotic strains, or they only regard probiotics as The effect of aiding digestion or increasing flavor, such as inactivated yogurt at room temperature, lactic acid bacteria flavored drinks, etc., has no significant effect on human health, and the effect of probiotics is far underestimated

Method used

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  • Probiotic composition for enhancing immunity and application of probiotic composition
  • Probiotic composition for enhancing immunity and application of probiotic composition
  • Probiotic composition for enhancing immunity and application of probiotic composition

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0034]Example 1: Screening of prebiotics for promoting K-MYL composite probiotics

[0035]In this example, the K-MYL probiotic combination was screened for growth-promoting prebiotics, so as to obtain a prebiotic combination that promotes the growth of probiotics. Take MRS medium (beef extract 10.0g, yeast extract 5.0g, protein peptone 10.0g, glucose 20.0g, K2HPO4 2.0g, sodium acetate 5.0g, MgSO4·7H2O 0.2g, MnSO4·4H2O 0.05g, Tween 80 1.0g, triammonium citrate 2.0g, agar 15.0g, add distilled water to 1000ml) as a basic medium, and add candidate prebiotics or prebiotic combinations to a final concentration of 10%. K-MYL composite probiotic lyophilized powder (containing Brady yeast powder 35%, Lactobacillus casei powder 15%, Lactobacillus bulgaricus 10%, Bifidobacterium animal powder 10%, Rhamnus Lactobacillus saccharobacillus powder 15%, Bifidobacterium longum powder 10%, Lactobacillus acidophilus powder 5%), static culture in anaerobic incubator for 6h, determine the OD of bacterial gr...

Embodiment 2

[0038]Example 2: Immunity-enhancing solid beverage

[0039]This embodiment provides a probiotic solid beverage that can maintain intestinal health and enhance immunity. The composition of each auxiliary material is shown in Table 2. After the raw materials are accurately weighed, they are gradually mixed and finally divided into 10 g / bag. After testing (refer to GB4789.35-2016 method description), except for products without probiotics 10, the number of viable probiotics in other solid beverages is 1.8-8.2×108CFU / g.

[0040]Table 2. Solid drinks to enhance immunity

[0041]

[0042]

Embodiment 3

[0043]Example 3: Yogurt for enhancing immunity

[0044]This embodiment provides a functional probiotic fermented yogurt that can maintain intestinal health and enhance immunity, which is composed of the following components by weight: 100g of fresh milk, 12g of white sugar, 250mg of yeast β-glucan, and 200mg of vitamin C , Sterilize at 95°C for 5min and cool to 40°C, inoculate 0.18g of K-MYL compound probiotic starter (20% of Streptococcus thermophilus freeze-dried powder, 15% of Lactobacillus bulgaricus freeze-dried powder, 20% of Lactobacillus casei freeze-dried powder %, Lactobacillus rhamnosus freeze-dried powder 20%, Lactobacillus bifidobacterium animal freeze-dried powder 15%, Lactobacillus acidophilus freeze-dried powder 10%), sealed and placed in a yogurt machine at 40 ℃ for 7-12h fermentation, then Place in a refrigerator at 4°C for 12h. In a clean environment, add 1% Brady yeast powder, stir evenly, and then pack, store at 4°C. After testing (refer to GB4789.35-2016 method de...

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Abstract

The present invention discloses a probiotic composition for enhancing immunity and an application of the probiotic composition. The probiotic composition comprises prebiotics, a K-MYL probiotic combination and functional substances, and the K-MYL probiotic combination comprises at least one of lactobacillus casei, lactobacillus bulgaricus, saccharomyces boulardii, lactobacillus reuteri and bifidobacterium animalis, or further comprises at least one of lactobacillus rhamnosus, lactobacillus acidophilus and bifidobacterium longum. The probiotic composition can significantly increase the number of intestinal effective microbial communities, improve intestinal immune functions, improve expressions of intestinal immune factors, resist virus infection and shorten recovery time after the virus infection. Moreover, probiotic strain combinations, the prebiotics, probiotic strains and the functional substances have remarkable synergistic enhancement effects.

Description

Technical field[0001]The present invention relates to the field of intestinal microflora regulation, in particular to an oral probiotic composition capable of enhancing immunity by regulating the intestinal microflora and resisting viral infection and its application.Background technique[0002]The human intestine provides a good habitat for microorganisms, and the number of microorganisms in the adult intestine is as high as 1014, Which is close to 10 times the number of human somatic cells; the mass reaches 1.2kg, which is close to the mass of human liver; the number of genes it contains is about 100 times that of the human body, and it has metabolic functions that the human body does not possess. As the human body’s largest and most complex microecosystem, the intestinal microbes themselves and their metabolites can not only regulate human health, but also play an important role as a bridge between the diet and the host, and are a very important part of the human health system. .[0...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A23C9/13A23L33/10A23L33/125A23L33/135A23L33/14A23L33/15A23L33/21A61K36/064A61K35/747A61K35/745A61P37/04A61P31/16
CPCA23L33/135A23L33/14A23L33/10A23L33/125A23L33/15A23L33/21A23C9/1307A23C9/13A23C9/1322A61K36/064A61K35/747A61K35/745A61P37/04A61P31/16A23V2002/00A23V2400/173A23V2400/125A23V2400/123A23V2400/515A23V2200/3204A23V2200/324A23V2250/76A23V2250/284A23V2250/632A23V2250/622A23V2250/5034A23V2250/708A61K2300/00
Inventor 刘海峰刘红皮婷婷李青山
Owner WUHAN KANGFUDE BIOTECH CO LTD
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