The invention discloses a suction cutting type percutaneous vertebral-plate-drilling precise depth-limiting trephine set for minimally invasive spine surgery, belonging to the field of medical instruments. The trephine set comprises a depth-limiting trephine, a depth-limiting soft-tissue strutting sleeve arranged at the bottom end of the depth-limiting trephine in a sleeving mode and detachably connected with the depth-limiting trephine, a depth-limiting grinding disc arranged in the depth-limiting trephine and detachably connected with the depth-limiting trephine, limiting buckles respectively arranged at the top end of the depth-limiting trephine and the top end of the depth-limiting grinding disc in a sleeving mode, and a saw ring arranged on the bottom side of the depth-limiting trephine. With the trephine set in the invention, a channel is opened up for further intraspinal operation of the spine; the trephine set is accurate, safe and efficient, changes the operation mode that a vertebral plate needs to be bitten and cut by a rongeur or needs to be ground off with a spherical high-speed grinding drill bit under X-ray fluoroscopy detection in traditional operation, avoids excessive excision injury to the vertebral plate and condiserable radiation exposure of doctors and patients, reduces interference with and injury to nearby peripheral soft tissues and nerve structures inspinal canalis vertebralis, and is convenient to operate, reduced in operation time, scientific in design, high in efficiency and good in safety.