15 results about "Nerve structure" patented technology

The present disclosure is directed to neural interface devices and methods that accesses the subarachnoid space to enable minimally invasive modulation and recording of neural structures. Exemplary embodiments may comprise an implantable pulse generator and a microelectrode catheter. In particular embodiments, the microelectrode catheter comprises one or more stimulating and recording electrodes. Exemplary embodiments may also include methods comprising performing a lumbar puncture to access the spinal subarachnoid space and advancing microcatheter through the spinal subarachnoid space.

The invention discloses a system for predicting the risk of nerve injury caused by radiotherapy based on deep learning, and belongs to the technical field of medical artificial intelligence and radiotherapy, and the system comprises a neural structure automatic segmentation module, a dose-neural response modeling module, an individualized risk assessment module, a radiotherapy plan optimization module and a closed-loop feedback regulation unit. The system adopts an encoder-decoder deep network to perform high-precision segmentation on nervous tissues, establishes a dose-nerve response quantitative model by fusing dosiomics and radiomics characteristics, and realizes individualized risk assessment based on a multi-factor risk quantitative network. An optimization scheme for balancing tumor control and neuroprotection is generated through Pareto optimal search, collaborative optimization of all the modules is achieved through closed-loop feedback, and decision support is provided for precise radiotherapy.

Systems and methods that deliver a continuous partial nerve conduction block are described. A waveform generator can configure one or more direct current (DC) waveforms to provide a continuous partial nerve conduction block. One or more electrodes can deliver the one or more DC waveforms to provide the partial block to the neural structure. Feedback can be provided to the waveform generator related to the partial block. The feedback includes monitoring a property associated with the partial block and altering a parameter associated with the one or more direct current waveforms in response to the property associated with the partial block.

1. The name of the design product: stereotactic apparatus (JS302). 2. The use of the design product: using the three-dimensional coordinate system defined by the marks on the skull or other reference points to determine the location of certain subcortical neural structures in order to stimulate, destroy, inject drugs, guide potential, etc. under non-direct exposure. 3. The design points of the design product: in shape. 4. The picture or photo that best shows the design points: stereogram 1.

The present application provides a nerve regulation system and method for the ventral epidural region of the spinal cord, wherein the nerve regulation system for the ventral epidural region of the spinal cord generates a multi-channel pulse width modulation signal by using a microprocessor, drives a voltage-controlled current source after amplitude adjustment, and outputs a stimulation current with adjustable frequency, pulse width and amplitude to act on the ventral nerve structure of the spinal cord. Real-time monitoring of the stimulation current of each channel is realized by combining voltage sampling and single-pole multi-throw analog switches, while the feedback information of multiple modal sensors such as body position, electromyography and pressure is integrated to construct a closed-loop control mechanism, realize dynamic adjustment and individual optimization of the electric stimulation parameters. The precise activation ability of motor and autonomic nerve function is enhanced, and the present application has the advantages of more accurate electric stimulation positioning, more sensitive reaction, more intelligent control and the like, and is suitable for intelligent rehabilitation intervention in scenes such as spinal cord injury, cerebral palsy, and nerve dysfunction.

A lateral retractor system for forming a pathway to a patient's intervertebral disc space includes a single dilator and a retractable dual-tapered-blade assembly. The dilator may feature a narrow rectangular body for insertion at an insertion orientation parallel to the fibers of the patient's psoas muscle, at an approximate 45-degree angle to the patient's spine. The retractable dual-tapered-blade assembly consists of only two blade subassemblies, each having a blade bordered by adjustable wings, along with built-in lighting and video capabilities. The dual-tapered-blade assembly may be passed over the single dilator at the insertion orientation and rotated approximately 45-50 degrees to a final rotated orientation parallel to the intervertebral disc space before the two blade subassemblies are retracted away from one another to create the surgical pathway, while simultaneously and continuously assessing for encroachment upon one or more nerve structures within 360-degrees of the instrument. Other embodiments are also disclosed.

This disclosure provides a method for selecting parameters for stimulation of the thalamus using a deep brain stimulator to treat a motor disorder in a subject, such as paralysis of the upper limb and face muscles. Also provided are methods for treating motor disorder in a subject. Also provided is an implantable electrode lead for neuromodulation and recording, configured to provide targeted stimulation and / or recording to multiple anatomically distinct neural structures, specifically the thalamus, the motor cortex, and optionally, the corona radiata, using a single continuous elongate lead body.

A lateral retractor system for forming a pathway to a patient's intervertebral disc space includes a single dilator and a retractable dual-tapered-blade assembly. The dilator may feature a narrow rectangular body for insertion at an insertion orientation parallel to the fibers of the patient's psoas muscle, at an approximate 45-degree angle to the patient's spine. The retractable dual-tapered-blade assembly consists of only two blade subassemblies, each having a blade bordered by adjustable wings, along with built-in lighting and video capabilities.The dual-tapered-blade assembly may be passed over the single dilator at the insertion orientation and rotated approximately 45-50 degrees to a final rotated orientation parallel to the intervertebral disc space before the two blade subassemblies are retracted away from one another to create the surgical pathway, while simultaneously and continuously assessing for encroachment upon one or more nerve structures within 360-degrees of the instrument. Other embodiments are also disclosed.

The invention relates to the technical field of intelligent monitoring, and particularly provides a neural function and intracranial environment integrated intelligent monitoring method and system.The method comprises the steps that intracranial blood vessel blood flow data, electroencephalogram data and retina nerve fiber layer thickness data are collected in real time and preprocessed; obtaining an ICP estimated value, a TCD pulsation index, EEG spectrum power and an optic nerve OCT thickness mean value; and performing correlation analysis and trend fusion on the ICP estimated value, the TCD pulsation index, the EEG spectrum power and the optic nerve OCT thickness mean value so as to realize integrated intelligent monitoring of the neural function and the intracranial environment. According to the method, correlation analysis can be carried out on the four types of key characteristic values, physiological internal correlation among intracranial pressure, hemodynamics, electroencephalogram physiology and optic nerve structures is mined, and the problem that key correlation information among indexes is prone to being missed in traditional manual analysis can be avoided; and meanwhile, through trend fusion, comprehensive research and judgment of a multi-index dynamic change trend are realized.

The utility model provides a novel retractor device applied to a subclavian approach endoscopic thyroid surgery, and particularly relates to the technical field of medical instruments. The novel retractor device applied to the subclavian approach endoscopic thyroid surgery comprises a handheld device, the two ends of the handheld device are fixedly connected with an upper retractor and a lower retractor respectively, the upper retractor comprises a horizontal end and a vertical end, the horizontal end and the vertical end are cylindrical, the bottom end of the lower retractor comprises a transverse end and a vertical end, and the transverse end and the vertical end are connected with the handheld device. And the transverse end and the vertical end are flat rectangles. The thyroid resection device has the advantages that the thyroid resection device can be used for single-side thyroid resection and double-side thyroid total resection, and the core of the thyroid resection device is unique structural design and operation mechanism. By means of innovative angle adjustment and traction functions, exposure of the thyroid superior pole and surrounding important nerve structures is remarkably improved, and the problems of insufficient exposure, high bleeding risk and nerve injury in the prior art are solved.

The application discloses a method and system for identification of blood vessels, lymph nodes and nerves in surgery, and relates to the technical field of computers, which comprises the following steps: S1, acquiring a surgery video, marking and establishing a blood vessel sample database, a lymph sample database and a nerve sample database; S2, constructing an initial identification model; S3, training the initial identification model to obtain a blood vessel identification model, a lymph identification model and a nerve identification model; S4, collecting the surgery video, and identifying and outlining the contours of blood vessels, lymph and nerves; and S5, visually displaying the surgery video and the contours to a surgeon; the system comprises a collection module, a central processing unit and a display module; the blood vessels, lymph and nerve structures under the laparoscopic surgery visual field are identified in real time by using an artificial intelligence computer model, and the visual display function is combined, so that the surgeon is provided with guidance for resection and avoidance of corresponding blood vessels, lymph nodes and nerves, the surgeon is guided to reasonably identify and resect blood vessels and lymph nodes, the blood vessels and lymph nodes that do not need to be resected are avoided, and the surgery is smoothly assisted.

The application discloses application of SKP-SC-EVs in preparation of DPN treatment drugs and belongs to the technical field of biological medicine.The SKP-SC-EVs in the application can be internalized by SCs, and can directly repair and protect damaged SCs in multiple dimensions, laying a good cell foundation for nerve regeneration, in contrast to other source EVs.In addition, through treatment of DPN model rats with the SKP-SC-EVs, it is proved that the SKP-SC-EVs can effectively improve the nerve sensory and motor functions of the DPN rats, promote the regeneration of the nerve structure and myelin sheath of the rats, enhance the nerve internal microcirculation blood flow, delay the atrophy and degenerative changes of the target muscle, and realize systematic repair of the three functional units of "nerve-vascular-muscle".The DPN treatment scheme provided by the application effectively overcomes the defects in the prior treatment schemes, i.e., single repair effect dimension and difficulty in realizing fundamental reconstruction of nerve functions and keeping long-term stability.

A method for the treatment of an auditory disease or condition in a human subject is provided comprising administering a therapeutic agent into a bony cavity of a cochlea of the subject that contains neural structures via the Round Window membrane of the cochlea. Also provided are therapeutic agents for use in such methods, as well as method for the delivery of therapeutic agents via the Round Window membrane of the cochlea.

In an illustrative embodiment, methods and system for increasing coagulation potential and / or triggering a higher platelet activation rate in a subject via auricular neurostimulation include contacting skin of the subject with one or more therapeutic electrodes, each electrode positioned in a respective region of nerve structures of the auriculotemporal nerve (ATN), nerve structures connected to the ATN, nerve structures of the auricular branch of the vagus nerve (ABVN), or nerve structures connected to the ABVN, applying, to the electrodes, one or more stimulation patterns.

The application provides a fine forceps for minimally invasive surgery, which comprises a main forceps handle, an outside surface of the angle adjusting ring is provided with an adjusting rod mechanism, and an outside surface of the adjusting rod mechanism is provided with a forceps head mechanism. Through the adjusting rod mechanism, in use, medical staff can increase the length of the forceps rod and the adjusting threaded rod by rotating the forceps rod and the adjusting threaded rod, then the medical staff tightly abut the upper connecting buckle and the lower connecting buckle, the first threaded hole and the second threaded hole are overlapped, the outer anti-skid pad is tightly abutted with the adjusting threaded rod, and the inner anti-skid pad is tightly abutted with the forceps rod, then the upper connecting buckle and the lower connecting buckle are fixedly connected through a pair of threaded rods, the working length of the separating forceps is accurately adjusted, important blood vessels and nerve structures can be effectively avoided when reaching and operating the target area, the accuracy and safety of the surgery are significantly improved, and the surgery time is greatly shortened.