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44 results about "Deep brain stimulator" patented technology

Deep brain stimulation (DBS) is a surgical procedure used to treat a variety of neurological disorders. A battery-powered stimulator —essentially a brain pacemaker—is implanted in the body and delivers electrical stimulation to the areas of the brain responsible for causing dystonia symptoms.

System and methods of deep brain stimulation for post-operation patients

A method for programming a deep brain stimulator implanted in a target region of a brain of a living subject for optimal stimulation, wherein the deep brain stimulator comprises at least one electrode having a plurality of electrode contacts spaced apart from each other, and any portion of the brain of the living subject is identifiable by a set of corresponding spatial coordinates. In one embodiment, the method comprises the steps of creating an efficacy atlas in which any spatial coordinates for a position in a target region of the brain of the living subject are related to a position with corresponding atlas coordinates in the efficacy atlas, and each position in the atlas coordinates of the efficacy atlas is associated with an efficacy of stimulation at a corresponding position in the spatial coordinates of the brain of the living subject; acquiring a position of each electrode contact of the at least one electrode in the spatial coordinates of the brain of the living subject; mapping the acquired position of each electrode contact of the at least one electrode in the spatial coordinates of the brain of the living subject onto a corresponding position in the efficacy atlas so as to determine the efficacy of stimulation at the acquired position in the spatial coordinates of the brain of the living subject; and selecting one or more electrode contacts having the highest efficacy for stimulation.
Owner:VANDERBILT UNIV

Cortical Implant System for Brain Stimulation and Recording

The present invention consists of an implantable device with at least one package that houses electronics that sends and receives data or signals, and optionally power, from an external system through at least one coil attached to at least one package and processes the data, including recordings of neural activity, and delivers electrical pulses to neural tissue through at least one array of multiple electrodes that are attached to the at least one package. The device is adapted to electrocorticographic (ECoG) and local field potential (LFP) signals. A brain stimulator, preferably a deep brain stimulator, stimulates the brain in response to neural recordings in a closed feedback loop. The device is advantageous in providing neuromodulation therapies for neurological disorders such as chronic pain, post traumatic stress disorder (PTSD), major depression, or similar disorders. The invention and components thereof are intended to be installed in the head, or on or in the cranium or on the dura, or on or in the brain.
Owner:CORTIGENT INC

Percutaneous closed-loop control charging device for implantation type medical treatment instrument

The invention discloses a percutaneous closed-loop control charging device for implantation type medical treatment instrument and belongs to the technical field of implantation medical instrument. The percutaneous closed-loop control charging device for implantation type medical treatment instrument comprises an external charger and an internal implantation type medical instrument. An external energy transmitting coil is a large-size flat magnetic core coil, and an internal energy receiving coil is a hollow coil; the external energy transmitting coil transmits electromagnetic energy by adopting a resonance electromagnetic coupling manner with parallel central shafts; and the electrical energy obtained by the internal energy receiving coil charges an internal rechargeable battery through an internal charge control circuit. The closed-loop control charging device communicates in a pulse position modulation manner for closed-loop control to ensure the energy received by the implantation medical instrument in different charging phases to be within the normal range, effectively control the heating and increase the safety; the closed-loop control charging device calculates the efficiency by the internal feedback parameter to realize counterpoint prompt and increase the charging efficiency. The percutaneous wireless charging method can charge the implantation type medical instrument by a titanium casing, is safe and reliable in charging, and can be applied to all types of implantation type medical instruments equivalent to a deep brain stimulator in power level.
Owner:TSINGHUA UNIV +1

Apparatus and methods of optimal placement of deep brain stimulator

ActiveUS20050004617A1Minimizes the voxel-by-voxel intensity differenceCharacter and pattern recognitionImplantable neurostimulatorsBrain deep stimulationPhysical therapy
A method of optimal placement of a deep brain stimulator in a targeted region of a brain of a living subject for optimal deep brain stimulation. In one embodiment, the method includes the steps of nonmanually selecting an initial optimal position from, refining the nonmanually selected initial optimal position to determine a final position, and placing the deep brain stimulator at the final position in the targeted region of the brain of the living subject.
Owner:VANDERBILT UNIV

Functionalized implantable flexible electrode and application thereof

The invention relates to a functionalized implantable flexible electrode and an application thereof. The functionalized implantable flexible electrode at least comprises a function layer capable of generating a current or voltage. In the invention, through adopting the function layer which can generate the current or the voltage via triggering, the flexible electrode does not need complex line connection and device packaging and the function of a nerve stimulation device can be realized so that an operation risk and the safety risk of long-term implantation are greatly reduced, and the application field of the nerve stimulation device is expanded. The invention also provides the applications of the above functionalized wide-width implantable electrode in manufacturing an implantable artificial retina, an implantable artificial cochlea, an implantable cardiac pacemaker, and an implantable deep brain stimulator.
Owner:SHENZHEN INST OF ADVANCED TECH

Sleep detection-based integrated closed loop deep brain stimulator

The invention provides a sleep detection-based integrated closed loop deep brain stimulator. The sleep detection-based integrated closed loop deep brain stimulator has a real-time sleep detection function, is capable of identifying the sleep or awake state of a patient and is capable of automatically adjustably outputting parameters of electrical stimulation in real time according to different states of the patient. When the patient is sleeping, a pulse generator automatically stops outputting the electrical stimulation or weakening the strength of the electrical stimulation output, and when the patient is awake, a normal operation mode of the pulse generator is recovered. On one hand, the system power consumption of the deep brain stimulator is favorably reduced, and thereby, the service life of the deep brain stimulator is prolonged, and on the other hand, the sleep detection-based integrated closed loop deep brain stimulator is favorable for reducing the harmful effects of the continuous high-frequency electrical simulation to the patient.
Owner:BEIJING PINS MEDICAL +1

Method for deep brain stimulation targeting based on brain connectivity

Due to the lack of internal anatomic detail with traditional magnetic resonance imaging, preoperative stereotactic planning for the treatment of tremor usually relies on indirect targeting based on atlas-derived coordinates. To overcome such disadvantages, a method is provided that allows for deep brain stimulation targeting based on brain connectivity. For example, probabilistic tractography-based thalamic segmentation for deep brain stimulator (DBS) targeting is suitable for the treatment of tremor.
Owner:RGT UNIV OF CALIFORNIA

Remote regulation and control method for deep brain stimulator based on 3G (3rd generation) network

The invention belongs to a remote regulation and control method for an implanted medical device, and particularly relates to a method for remote regulation control as well as tracking survey of patient state of an implanted deep brain stimulator. The system is based on the SIP (session initiation protocol) and RTP (real-time transport protocol) as well as Bluetooth communication mode of the 3G (3rd generation) communication network, and realizes one-to-one visual safe remote regulation and control. The system mainly comprises a control end 1, a 3G mobile communication network 2, a client 3, aprogram controller 4 and an implanted pulse generator 5. The regulation and control method comprises the following steps: a doctor looks for relevant information of a patient through a computer 6 of the control end 1 and a 3G mobile phone 8, observes the physical sign of the patient, selects proper adjustment parameters and sends the adjustment parameters to the client 3 through the 3G mobile communication network 2; the client 3 communicates with the program controller 10 through a Bluetooth protocol; and the program controller 10 controls the pulse generator 11 and reversely returns the feedback information to the control end. According to the invention, the physical sign information of the patient can be acquired anytime and anywhere, the stimulation pulse parameters are adjusted, and the clinical requirements on tracking visit and quick diagnosis of the patient with the implanted deep brain stimulator are met; and moreover, as the public wireless communication network and common communication equipment are used, the cost is low, the reliability is high, and the practicability is strong.
Owner:中国人民解放军第四军医大学唐都医院

Multiple lead method for deep brain stimulation

New methods for deep brain stimulation (DBS) surgery using two or more electrical leads are provided. The methods are useful for treating a wide variety of brain-associated disorders including movement-related disorders, psychiatric disorders, metabolic / eating disorders, memory disorders, and pain. Methods featuring stimulation of distinct target areas of a subject's brain, such as the thalamic ventralis intermedius (VIM) and the ventralis oralis (VOA / VOP) using multiple electrical leads for treatment of tremor provide superior clinical outcomes to stimulation with single leads implanted in these target areas.
Owner:UNIV OF FLORIDA RES FOUNDATION INC

Skull-Mounted Deep Brain Stimulator

An Implantable Pulse Generator (IPG) operable as a Deep Brain Stimulator (DBS) is disclosed which is mountable to the skull of a DBS patient, and which therefore is much closer to the site of intended therapy. The IPG includes an electronics section, a charging coil section, a connector block section configured to connect to the proximal end of implanted leads, and an electrode wire section connecting the connector block section to the electronics section. The electronic section includes a housing that is positionable into a hole formed in the patient's skull. Once so positioned, the housing may be affixed to the skull via bone screws. The charging coil section may be separate from and non-overlapping with the electronics section, or the charging coil section may encircle the electronics section.
Owner:BOSTON SCI NEUROMODULATION CORP

Electrical neurostimulator package

Described herein is technology relevant to the field of implantable electrical neurostimulators. For example, embodiments include but are not limited to cochlear implants, implantable hearing aids, deep brain stimulators and pain control devices, as well as constituent components of such devices, methods for their manufacture, and methods for their use. For the present purposes, embodiments are described particularly by reference to exemplary cochlear implants, although that should not be regarded as necessarily limiting on the underlying concepts.
Owner:NEUROSTIMULATION DEVICES & TECH

External deep brain stimulator and self-aligning device thereof

An external deep stimulator for brain and its aligning unit are disclosed. The stimulator has external exciting coil and the induction output coil in human body for the coupling between internal and external signals. The aligning unit has the external permanent magnet close to said exciting coil and two magnetic cores respectively arranged in said exciting coil and induction output coil.
Owner:TIANJIN UNIV

Spiraled wires in a deep-brain stimulator probe

The present invention regards a probe for deep brain stimulation (DBS), with high overall impedance, but low overall resistance. This is achieved since the probe comprises a structure comprising at least two interconnected spirals, wherein said two spirals have different direction of rotation. A system for deep brain stimulation comprising the probe, a power source and an electrode is also disclosed.
Owner:SAPIENS STEERING BRAIN STIMULATION

Class D amplifier driven external deep brain stimulator

The present invention relates to deep brain stimulator and belongs to the field of medical equipment. The class D amplifier driven external deep brain stimulator includes one in vivo signal stimulating part, one in vitro signal generating and controlling part, and one signal coupling module for signal coupling between the two foregoing parts. The in vivo signal stimulating part includes one pair of stimulating electrodes; and the in vitro signal generating and controlling part includes one class D amplifier and pulse driver module, one micro controller module. The pulse signal the micro controller module generates is amplified in the class D amplifier and pulse driver module and introduced with the signal coupling module to body to excite the stimulating electrode pair. The present invention has the advantages of low power consumption and high efficiency. The in vivo inducing output coil and stimulating electrodes are implanted via once operation and need no power source.
Owner:TIANJIN UNIV

Programming systems for deep brain stimulator system

The present technology provides a medical stimulation system having a clinical programmer configured to operate on a computational and memory device having a wireless communication device. The technology also provides a neurostimulator configured to wirelessly communicate with the clinical programmer. The neurostimulator also includes a pulse generator operatively coupled with an electrode by a lead. The pulse generator is configured to transmit an electrical signal comprising a repeating succession of non-regular pulse trains. Each pulse train includes a plurality of pulses having non-regular, non-random, differing inter-pulse intervals therebetween. The pulse trains repeat in succession to treat a neurological condition. Further, the pulse trains are initiated by instructions communicated by the clinical programmer.
Owner:DEEP BRAIN INNOVATIONS

Current pulse amplitude calibration method applied to DBS and automatic calibration acquisition circuit

The invention provides a current pulse amplitude calibration method applied to a DBS and an automatic calibration acquisition circuit. The automatic calibration acquisition circuit in a deep brain stimulator DBS circuit is used for acquiring a current pulse amplitude; and through a current pulse amplitude calibration method, according to the acquired actual output current pulse amplitude, an inputvalue of DAC is continuously adjusted so that the actual output current pulse amplitude corresponding to each current is equal to a theoretical output current pulse amplitude or approaches the theoretical output current pulse amplitude within a tolerance range. The calibrated actual output current pulse amplitude better meets an output requirement of the deep brain stimulator DBS circuit, and output precision is relatively high.
Owner:SHAANXI QINMING MEDICAL CO LTD

Battery-free flexible implantable deep brain stimulator, battery-free flexible implantable deep brain stimulator system and preparation method

The invention discloses a battery-free flexible implantable deep brain stimulator, a battery-free flexible implantable deep brain stimulator system and a battery-free flexible implantable deep brain stimulator preparation method, and belongs to the field of implantable biomedical equipment. Comprising a piezoelectric device used for receiving a pulse ultrasonic signal with the fundamental frequency of 1 MHz emitted by an in-vitro ultrasonic generator and generating an alternating current signal with the stimulation frequency and the stimulation duration consistent with those of the pulse ultrasonic signal through the piezoelectric effect; the rectifying circuit is used for converting the alternating-current electric signal into a direct-current electric signal; the stimulating electrode is used for applying a direct-current electric signal to a target brain region; the piezoelectric device is a piezoelectric array composed of a plurality of square Sm doped PMN-PT piezoelectric single crystal blocks with the center frequency of 1 MHz. Square Sm-doped PMN-PT piezoelectric single crystal blocks with the center frequency being 1 MHz are adopted to form the piezoelectric array, and due to the fact that the Sm-doped PMN-PT array of a specific structure is adopted, it is ensured that the maximum output power can be obtained in the resonant state with the resonant frequency being 1 MHz, and wireless, battery-free and safe real-time deep brain stimulation is achieved.
Owner:HUAZHONG UNIV OF SCI & TECH

Percutaneous closed-loop control charging device for implantation type medical treatment instrument

The invention discloses a percutaneous closed-loop control charging device for implantation type medical treatment instrument and belongs to the technical field of implantation medical instrument. The percutaneous closed-loop control charging device for implantation type medical treatment instrument comprises an external charger and an internal implantation type medical instrument. An external energy transmitting coil is a large-size flat magnetic core coil, and an internal energy receiving coil is a hollow coil; the external energy transmitting coil transmits electromagnetic energy by adopting a resonance electromagnetic coupling manner with parallel central shafts; and the electrical energy obtained by the internal energy receiving coil charges an internal rechargeable battery through an internal charge control circuit. The closed-loop control charging device communicates in a pulse position modulation manner for closed-loop control to ensure the energy received by the implantation medical instrument in different charging phases to be within the normal range, effectively control the heating and increase the safety; the closed-loop control charging device calculates the efficiency by the internal feedback parameter to realize counterpoint prompt and increase the charging efficiency. The percutaneous wireless charging method can charge the implantation type medical instrument by a titanium casing, is safe and reliable in charging, and can be applied to all types of implantation type medical instruments equivalent to a deep brain stimulator in power level.
Owner:TSINGHUA UNIV +1

Biocompatible and Implantable Optical Conduits

The present disclosure provides advantageous optical conduit assemblies (e.g., biocompatible and implantable optical conduit assemblies), and related methods of use. More particularly, the present disclosure provides advantageous optical conduit assemblies (e.g., polydimethylsiloxane (“PDMS”)-based optical conduit assemblies) configured to power implantable devices (e.g., neural micro-stimulators or deep brain stimulators or the like) or to be used in optogenetic stimulation. In general, the exemplary optical conduit assemblies can be used for applications where energy needs to be transmitted to deep locations inside the body or brain without using electrical wires. Therefore, implantable devices that need to be powered (e.g., neural prosthetics) can be powered from an external light source using an optical conduit and an optical-to-electrical converter (e.g., a photodiode) attached to the end of the optical conduit on the inside.
Owner:NEW JERSEY INSTITUTE OF TECHNOLOGY

Impedance measuring device and method on basis of deep brain stimulator electrodes

The invention discloses an impedance measuring device and method on the basis of deep brain stimulator electrodes. The device comprises a pulse emitting circuit, a signal amplifying circuit, an analog-to-digital conversion circuit, a processing controller, an electrode terminal selection module and the deep brain stimulator electrodes, wherein an output end of the processing controller is connected to a control end of the pulse emitting circuit and a control end of the electrode terminal selection module, an output end of the pulse emitting circuit is connected to the deep brain stimulator electrodes through the electrode terminal selection module, an input end of the signal amplifying circuit is connected to the deep brain stimulator electrodes through the electrode terminal selection module, and an output end of the signal amplifying circuit is connected to the processing controller through the analog-to-digital conversion circuit. The device and method can measure a contact impedance value between the deep brain stimulator electrodes and brain tissue and an impedance value among different pieces of the brain tissue.
Owner:SHAANXI QINMING MEDICAL CO LTD

Fast-charging controlled deep brain stimulation bleeding detection system

The invention discloses a multi-battery charging controlled deep brain stimulation bleeding detection system, which comprises at least one deep brain stimulator and an in vitro device, wherein the deep brain stimulator comprises a stimulation electrode as well as a hemoglobin sensor, a pulse generator module, a charging coil, at least one main battery, at least one standby battery, a processor module and a first communication module which are arranged nearby the hemoglobin sensor; the in vitro device comprises a second communication module and an early warning module; under the control of the processor module, the charging coil is in charge of charging up the at least one main battery and the at least one standby battery; and meanwhile, the processor module is used for controlling the at least one standby battery to charge up the at least one main battery and for regulating charging current in accordance with a voltage value of a cell of the main battery. With the application of the charging mode, electric energy of the deep brain stimulation bleeding detection system can be rapidly supplemented.
Owner:BEIJING PINS MEDICAL

Programming system for deep brain stimulator systems

The present technology provides a medical stimulation system having a clinical programmer configured to operate on a computing and storage device with a wireless communication device. The present technology also provides a neurostimulator configured to communicate wirelessly with a clinical programmer. The neurostimulator also includes a pulse generator operably coupled to the electrodes via leads. The pulse generator is configured to transmit an electrical signal comprising a continuously repeating irregular train of pulses. Each pulse train consists of multiple pulses with irregular, non-random, different pulse intervals between them. The pulse train is repeated continuously to treat neurological diseases. Additionally, the burst is initiated by instructions transmitted by the clinical programmer.
Owner:DEEP BRAIN INNOVATIONS

Power monitoring method and power monitoring system of deep brain stimulator

The invention relates to a power monitoring method of a deep brain stimulator and a power monitoring system employing the method. The method comprises the steps of acquiring the stimulation parameters of a deep brain stimulator, calculating the battery-related parameters of the deep brain stimulator through a support vector machine prediction model, and displaying the calculated battery parameters to a user. According to the power monitoring method and the power monitoring system of a deep brain stimulator provided by the invention, the power of a deep brain stimulator can be predicted with high precision. Through the prediction scheme, DBS power monitoring and service life assessment under each stimulation parameter combination and patient's individual condition based on clinical specificity can be realized. The method and the system are of certain reliability, and can be applied to clinical practice eventually.
Owner:BEIJING PINS MEDICAL +1
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