121 results about "Partial field" patented technology

A method, apparatus, and system for treating patients suffering from movement disorders having the ability to determine one or more biomarkers indicative of a disease state. In some embodiments, the biomarker may be used as a closed-loop feedback signal to control the delivery of therapy (such as electrical stimulation or drug therapy), and which may also be used as an indication of therapy effectiveness. One embodiment uses electrodes placed in the brain to measure EEG or local field potential (LFP) signals, from which the one or more biomarkers may be determined.

A system for determining electrophysiological data comprising an electronic control unit configured to acquire electrophysiology signals from a plurality of electrodes (130) of one or more catheters, select at least one clique of electrodes from the plurality of electrodes (136) to determine a plurality of local E field data points, determine the location and orientation of the plurality of electrodes, process the electrophysiology signals from the at least one clique from a full set of bipole subcliques to derive the local E field data points associated with the at least one clique of electrodes, derive at least one orientation independent signal from the at least one clique of electrodes (138) from the information content corresponding to weighted parts of electrogram signals, and display or output catheter orientation independent electrophysiologic information to a user or process.

The present invention consists of an implantable device with at least one package that houses electronics that sends and receives data or signals, and optionally power, from an external system through at least one coil attached to at least one package and processes the data, including recordings of neural activity, and delivers electrical pulses to neural tissue through at least one array of multiple electrodes that are attached to the at least one package. The device is adapted to electrocorticographic (ECoG) and local field potential (LFP) signals. A brain stimulator, preferably a deep brain stimulator, stimulates the brain in response to neural recordings in a closed feedback loop. The device is advantageous in providing neuromodulation therapies for neurological disorders such as chronic pain, post traumatic stress disorder (PTSD), major depression, or similar disorders. The invention and components thereof are intended to be installed in the head, or on or in the cranium or on the dura, or on or in the brain.

A method, apparatus, and system for treating patients suffering from movement disorders having the ability to determine one or more biomarkers indicative of a disease state. In some embodiments, the biomarker may be used as a closed-loop feedback signal to control the delivery of therapy (such as electrical stimulation or drug therapy), and which may also be used as an indication of therapy effectiveness. One embodiment uses electrodes placed in the brain to measure EEG or local field potential (LFP) signals, from which the one or more biomarkers may be determined.

A lithographic apparatus includes an illumination system including a field faceted mirror including a plurality of field facets and configured to receive radiation from a radiation source and form a plurality of images of the radiation source on corresponding pupil facets of a pupil faceted mirror. Each of the field facets is configured to provide an illumination slit at a level of a patterning device. The illumination slits are summed together at the level of the patterning device to illuminate the patterning device. First blades are configured to block radiation from a radiation source and each first blade is selectively actuable to cover a portion of a selectable number of field facets. The field faceted mirror further comprises partial field facets, the partial field facets being configured to produce a partial illumination slit at the level of the patterning device, and the pupil faceted mirror further includes pupil facets corresponding to the partial field facets. The partial field facets are configured to produce an illumination slit that is summed with the summed illumination slits of the field facets and / or correct for non-uniformity in the summed illumination slits of the field facets. Second blades are selectively actuable to cover a portion of a selectable number of partial field facets.

Monitoring brain neural activity comprises repeatedly applying electrical stimuli to evoke neural responses in the brain. Neural responses evoked by the stimuli are recorded. The recorded neural responses are assessed for changed characteristics over time, to monitor a time-varying effect on the recorded neural responses of local field potentials arising from a source other than the electrical stimuli.

A signal transmitting and receiving system to track the position and orientation of limb segments in order to provide feedback information for the control of the limb movement. The user will generally be seated in a wheelchair that provides a structure upon which orthogonal and / or non-orthogonally oriented coils can be mounted and energized selectively so as to create variously oriented magnetic fields. Multiple wireless sensors injected into the limb detect the local field strength and send information telemetrically to a central controller. The controller extracts information about the position and orientation of each limb segment by combining signals from various sensors according to calibration information and optimal filtering methods for extracting information from multiple nonlinear sensors in mechanically constrained systems.

An assembly for writing / reading high-density data on a recording media as a series of tags comprising a magnetic information bit pattern. The assembly includes an antenna positionable near the media; a source of electromagnetic radiation for producing an incident wave at least a portion of which can be coupled to the antenna; and, a means for coordinating a mutual positioning of the source of the electromagnetic radiation and the antenna, so that the antenna can generate a highly localized electromagnetic field in the vicinity of the media for inducing localized heating of the media. The assembly is capable of writing / erasing said high-density data by using an information signal for modulating the localized field generated in the vicinity of the media; the assembly is capable of reading by coordinating the mutual positioning of the antenna and the media.

The invention provides a muck monitoring system. On the basis of arrangement of an RFID identification module, a sensing module, a video monitoring module, a GPS postponing module, a monitoring terminal and a background server, intelligent clients of a GPS vehicle-mounted terminal, an RFID identification device, a mobile video terminal, and a hand-held terminal are used as carriers and a mobile packet communication network and a server system are used for connection. Therefore, the engineering muck monitoring range is extended from the partial field and transport monitoring to the whole process including production, clearing, and absorption, thereby realizing the overall effective monitoring of the muck and realizing good treatment of building rubbishes on the premise of guarantee of protection of urban resident lives and high security of the urban traffic.

A new hybrid nanoparticle, i.e., a nanorice particle, which combines the intense local fields of nanorods with the highly tunable plasmon resonances of nanoshells, is described herein. This geometry possesses far greater structural tunability than previous nanoparticle geometries, along with much larger local field enhancements and far greater sensitivity as a surface plasmon resonance (SPR) nanosensor than presently known dielectric-conductive material nanostructures. In an embodiment, a nanoparticle comprises a prolate spheroid-shaped core having a first aspect ratio. The nanoparticle also comprises at least one conductive shell surrounding said prolate spheroid-shaped core. The nanoparticle has a surface plasmon resonance sensitivity of at least 600 nm RIU−1. Methods of making the disclosed nanorice particles are also described herein.

An ambulatory intrinsic brain signal processor circuit is coupled to a plurality of electrodes. The signal processor circuit can include a digital multiplexer circuit coupled to the electrodes to multiplex brain signal data from different electrodes together into a multiplexed data stream. An ambulatory transceiver circuit wirelessly communicates information to and from a remote transceiver. A controller circuit permits a user to control which of the electrodes contribute data, a data resolution, and whether the data includes one or both of neural action or local field potential data. Seizure prediction components and methods are also described.

A device for assessing the effects of diffusible molecules on electrophysiological recordings from multiple neurons allows for the infusion of reagents through a cannula located among an array of microelectrodes. The device can easily be customized to target specific neural structures. It is designed to be chronically implanted so that isolated neural units and local field potentials are recorded over the course of several weeks or months. Multivariate statistical and spectral analysis of electrophysiological signals acquired using this system could quantitatively identify electrical “signatures” of therapeutically useful drugs.

A new hybrid nanoparticle, i.e., a nanorice particle, which combines the intense local fields of nanorods with the highly tunable plasmon resonances of nanoshells, is described herein. This geometry possesses far greater structural tunability than previous nanoparticle geometries, along with much larger local field enhancements and far greater sensitivity as a surface plasmon resonance (SPR) nanosensor than presently known dielectric-conductive material nanostructures. In an embodiment, a nanoparticle comprises a prolate spheroid-shaped core having a first aspect ratio. The nanoparticle also comprises at least one conductive shell surrounding said prolate spheroid-shaped core. The nanoparticle has a surface plasmon resonance sensitivity of at least 600 nm RIU−1. Methods of making the disclosed nanorice particles are also described herein.

Improved superconducting coils for a nuclear magnetic resonance probe use capacitive elements that are located in regions further from an active sample volume than magnetic field generating elements to which they are electrically connected. The sample volume is a substantially oblong shape, and the magnetic field generating elements run substantially parallel to the major axis of the shape, while the capacitor elements run perpendicular to the major axis. Gaps between the capacitor elements, and the width of the elements themselves, may increase toward the outside of the coil to minimize electrical discharge. The variation may be according to a monotonic, possibly linear, function. Discharge may also be minimized by using a dielectric cover that, together with a coil substrate, encloses the coil.

The invention provides a method for providing different quality of service (QoS) policies for data flow, mainly comprising: customizing ACL (access control list) template containing partial field information of each layer; using the ACL template to classify data flow and providing different QoS policies for the data flow. And it can implement flexible ACL type selection according to user requirements, implementing more fine grained data flow classification and providing corresponding different QoS policies for the data flow.

Using resonant interactions to directly and tomographically image neural activity in the human brain using magnetic resonance imaging (MRI) techniques at ultra-low field (ULF), the present inventors have established an approach that is sensitive to magnetic field distributions local to the spin population in cortex at the Larmor frequency of the measurement field. Because the Larmor frequency can be readily manipulated (through varying Bm), one can also envision using ULF-DNI to image the frequency distribution of the local fields in cortex. Such information, taken together with simultaneous acquisition of MEG and ULF-NMR signals, enables non-invasive exploration of the correlation between local fields induced by neural activity in cortex and more ‘distant’ measures of brain activity such as MEG and EEG.

A system is provided for stimulating one or more cells, wherein the stimulation is sub-threshold and may alter a transmembrane potential of the one or more cells. For some populations of cells it may be possible to affect the transmembrane potential to gain a therapeutic benefit. Cells of the sino-atrial node spontaneously depolarize predominantly due to the slow depolarization of transmembrane potential. The present system may provide sino-atrial cells with a local field stimulation that while not eliciting an action potential may nonetheless alter local transmembrane potential. Such alteration of transmembrane potential may permit an increase or decrease in a rate of depolarization, and hence modify heart rate.

This invention provides a field of view expander (FOVE) removably attached to a vision system camera having an image sensor defining an image plane. In an embodiment the FOVE includes first and second mirrors that transmit light from a scene in respective first and second partial fields of view along first and second optical axes. Third and fourth mirrors respectively receive reflected light from the first and second mirrors. The third and fourth mirrors reflect the received light onto the image plane in a first strip and a second strip adjacent to the first strip. The first and second optical axes are approximately parallel and a first focused optical path length between the scene and the image plane and a second focused optical path between the image plane and the scene are approximately equal in length. The optical path can be rotated at a right angle in embodiments.

The present invention pertains to an electromechanical actuator controlling a valve of an internal combustion engine by means of a first magnetic field, generated in a variable manner by an electromagnet, and a second magnetic field, generated by at least one magnet associated with the electromagnet. According to the present invention, the actuator is characterized in that it comprises at least one connecting part forming a magnetic circuit facilitating the passage of the flux generated by the electromagnet for part of the field generated by the magnet, the connecting part being magnetically saturated by the partial field of the magnet.

Film mode detection with bad edit detection used in de-interlacing video includes use of combing artifact detection in both 3-2 pull down detection and 2-2 pull down detection. Further, combing artifact detection uses only two field memories by accumulation of partial field statistics for comparisons.

One aspect of the invention provides a method of predicting a seizure in a subject comprising: (a) recording single neuron activity for a plurality of interneurons within the subject's mesial temporal lobe; (b) recording local field potential (LFP) within the subject's mesial temporal lobe; (c) measuring interneuron synchrony within the subject's mesial temporal lobe; and (d) detecting a pattern of interneuron activity and interneuron synchrony within the subject's mesial temporal lobe associated with an increased likelihood of a seizure. Another aspect of the invention provides a method for preventing a seizure in a subject comprising: (a) performing any one of the methods described herein; and (b) upon detection of the pattern, administering a therapeutically effective intervention to the subject to prevent onset of a seizure. Another aspect of the invention provides a non-transitory computer readable medium containing computer-readable program code including instructions for performing any of the methods described herein.

A diffractive interferometric optical device is provided for measuring spectral properties of light. The device includes means for coupling in a single spatial mode of an incoming light field to be examined, means for splitting the single spatial mode of incoming light field into at least two partial fields, means for changing one of a shape or a direction of propagation of the wavefront of at least one of the at least two partial fields in dependence on the wavelength and means for generating an interference pattern superimposing the at least two partial fields. The device further comprises detection means to record and evaluate the interference pattern at a plurality of discrete spatial positions in order to derive spectral properties of the incoming light field.

The invention relates to a method and device for orienting magnetisable particles (4) in a kneadable material (3), in particular steel fibres or rings in unhardened concrete by means of an orienting body (1) provided with a non-magnetic wall comprising a front face section (1a) and a rear face section (1b). A kneadable material (33) and the front face section (1a) of the orientation body (1) are first and foremost displaced with respect to each other. The orientation body (1) is also provided with a magnetic unit (2) which is disposed on the internal side of said front face section (1a) and generates a periodically variable magnetic field acting on the kneadable material in order to orient the magnetisable particles (4). Said invention is characterised in that said magnetic field is divided into at least two areas (I II) containing the partial fields exhibiting different forces and / or different directions of force lines. The partial field of the first area (I) applies long trajectory orientation and attractive forces on the particles, the partial field of the second area (II) releasing orientedly positioned particles.

The invention discloses a method of a layout design of a laterally diffused MOS transistor, which adopts the grid-shaped layout design and designs wells of a source region and a drain region of the laterally diffused MOS transistor in square shape, each well as the source region is surrounded by the well as the drain region, and each well as the drain region is surrounded by the well as the source region at the same time, then a square region with a smaller side length is defined as an active region of the drain region in the square of the well as the drain region, the well as the source region and a thin oxide layer defining region of the drain region are acted as an active region, and the rest annular part of the well as the drain region is acted as a field oxide region, polycrystalline silicon is arranged at the connecting part of the square of the source region and the square of the drain region and covers whole channel region and partial field oxide region, and a buried layer ion implantation region is added below a silicon epitaxial layer of the whole region. The method of the layout design can realize the optimization of the array area.

In an embodiment, an imprint apparatus can include a substrate holder having a chucking region and a recessed support section; and a template holder, wherein the chucking region has more area as compared to a template region. In another embodiment, an imprint apparatus can include gas zones; and a gas controller that can be configured to adjust pressures within the gas zones to induce a convex curvature of a partial field of a workpiece used with the imprint apparatus. A method can include providing a workpiece within an imprint apparatus, wherein the workpiece includes a substrate and a formable material; and initially contacting a template with the formable material at a location spaced apart from the periphery of a partial field. In a particular embodiment, the method can further include modulating the substrate to form a convex shape contacting the template with the formable material.

In learning for an interlocking trees datastore or KStore, the process is made more efficient by noting the (n-level) address within the KStore during the learning of each particle. In a pre-particle stream of data, which may be organized within or before the Learn Engine prior to this, “Marks” and “References” are inserted. Each Mark identifies where any number of References may start the learning process, enabling the avoidance of re-learning redundant data. Thus, in a field record data set, the redundant data fields (or even partial fields) can be skipped over and only the new data learned. The Marks and References are removed before processing into a particle stream. When particles are learned the K Engine returns the n-level address or pointer(s) which the Learn Engine uses to associate with the relevant Reference(s). The system can be implemented in hardware if desired to speed processing. No limit to the distribution or numbers of KStores, Learn Engines being used or K Engines being used is indicated.

The invention discloses an LDMOS device formed on a silicon substrate. An active area is isolated by a shallow groove field oxide, a partial field oxide is adopted in a drain region field oxide in a drift region between a channel region and a drain region, the partial field oxide is formed by partial field oxidation after silicon in the partial field oxide region is etched by a certain depth, and the depth of the partial field oxide is defined by the depth of the etched silicon in the partial field oxide region. The invention further discloses a manufacturing method of the LDMOS device. According to the LDMOS device and the manufacturing method of the LDMOS device, a smooth bottom is formed in the drain area through partial field oxide, and therefore the problem that current and an electricity field are centralized at the bottom of the field oxide of the drain region can be solved, and the breakdown voltage of the device can be improved; the length of the current path of the drain region of the device can be shortened, so the specific on-resistance of the device can be lowered, and the current performance of the device can be improved.

A neuron recording system was provided. By using the gain-boosted topology, the amplifier input impedance can be increased while simultaneously reducing the noise. The system can be configured to record local field potentials (LFPs) and neuron spikes, respectively, with low-power consumption. With the flexible digital controller module (DCM), any subset of the recording channels can be activated for recording with independent sampling rate at each channel. A wireless interface to transmit recorded neuron data and an on-chip neuron processor to perform real-time signal processing can be incorporated in the system.

The invention belongs to the field of neuroscience experiment, technology and research, and particularly relates to a method and a system for overall multi-site simultaneous recording and multiple brain area functional linkage monitoring. The system comprises a signal acquisition unit and a signal analysis unit which are connected through parallel interfaces, wherein the signal acquisition unit comprises an amplifier, an analog-digital converter, a microprocessor and a data signal transmission interface and simultaneously records the bioelectrical signals at different sites in the brain, the bioelectrical signals are amplified by the amplifier and converted into digital signals by the analog-digital converter, and the digital signals are transmitted to the signal analysis unit; and the signal analysis unit comprises a computer and analysis software, wherein the analysis software analyzes the digital signal from the signal acquisition unit. At the same time, the recorded bioelectrical signals are random combinations of local field potentials at different sites and central nucleus unit discharge activities. The system provides scientific research with a proactive tool for multi-site simultaneous recording and multiple brain area functional linkage monitoring of a nervous system.