164 results about "Biomedical equipment" patented technology

This invention includes a wettable biomedical device containing a high molecular weight hydrophilic polymer and a hydroxyl-functionalized silicone-containing monomer.

Bioscaffoldings formed of hydrogels that are crosslinked in situ in an infarcted region of the heart (myocardium) by a Michael's addition reaction or by a disulfide bond formed by an oxidative process are described. Each of the bioscaffoldings described includes hyaluronan as one of the hydrogel components and the other component is selected from collagen, collagen-laminin, poly-l-lysine, and fibrin. The bioscaffolding may further include an alginate component. The bioscaffoldings may have biofunctional groups such as angiogenic factors and stem cell homing factors bound to the collagen, collagen-laminin, poly-l-lysine, or fibrinogen hydrogel component. In particular, the biofunctional groups may be PR11, PR39, VEGF, bFGF, a polyarginine / DNA plasmid complex, or a DNA / polyethyleneimine (PEI) complex. Additionally, the hydrogel components may be injected into the infarct region along with stem cells and microspheres containing stem cell homing factors. The bioscaffolding may be formed on a stent or a cardiac medical device.

A system providing an inductive power and data link between an external transmitter and miniature internal receiver is presented. The system is suited to applications where the receiver must be of a small size and the system must consume very little power, such as an implanted biomedical device. The system is also compatible with systems where bi-directional communications are required. The novel transmitter and receiver form an improved forward data telemetry system. The transmitter consists of a Class-E converter with its optimum operating frequency being synchronously, instantaneously and efficiently altered in accordance with the data to be transmitted, thereby producing an FSK modulated magnetic field of substantially constant amplitude. The constant amplitude output allows for the continuous, data-independent transfer of power to the miniature receiver and its associated electronics. The present invention also represents an improvement over the high efficiency Class-E converters previously patented by the inventors. The receiver consists of a coil and an integrated rectifying system to recover operating power from the incident magnetic field, as well as an FSK demodulator whose operation is based on the multiphase comparison of charging times of integrated capacitors. The described FSK demodulator approach removes deleterious effects resulting from low-frequency changes in the transmitter frequency, and eliminates time distortion artifacts generated by circuit imbalances and asymmetries in the power recovery process. The combination of the transmitter and receiver improvements yields a reliable data transfer system unaffected by circuit imbalances and incidental variations in the amplitude and frequency of the magnetic field.

The present invention provides a glucokinase protein in which the catalytic activity has been disabled in order to enable its use as a glucose sensor. The catalytically disabled glucokinase protein can be used as the glucose sensor in hand-held glucose monitors and in implantable glucose monitoring devices. The glucose sensor can also be incorporated into biomedical devices for the continuous monitoring of glucose and administration of insulin.

Methods and apparatus for the direct deposition or patterning of biological materials and compatible biomaterials. The method is capable of depositing biological materials and biomaterials in a computer defined pattern, and uses aerodynamic focusing of an aerosol stream to deposit mesoscale patterns onto planar or non-planar targets without the use of masks or modified environments. The aerosolized compositions may be processed before deposition (pre-processing) or after deposition on the target (post-processing). Depositable materials include, not are not limited to conductive metal precursors, nanoparticle metal inks, dielectric and resistor pastes, biocompatible polymers, and a range of biomolecules including peptides, viruses, proteinaceous enzymes, extra-cellular matrix biomolecules, as well as whole bacterial, yeast, and mammalian cell suspensions. The targets may be planar or non-planar, and are optionally biocompatible. Applications include biosensor rapid prototyping and microfabrication, lab-on-chip manufacturing, biocompatible electroactive polymer development (ambient temperature bio-production of electronic circuitry), and various additive biomaterial processes for hybrid BioMEMS, Bio-Optics, and microfabrication of biomedical devices.

Methods and apparatus to form biocompatible energization elements are described. In some embodiments, the methods and apparatus to form the biocompatible energization elements involve forming cavities comprising active cathode chemistry. The active elements of the cathode and anode are sealed with a laminate stack of biocompatible material. In some embodiments, a field of use for the methods and apparatus may include any biocompatible device or product that requires energization elements.

Biomedical devices are provided herein which are formed from a polymerization product of a monomeric mixture comprising one or more monomers comprising one or more trifluorovinyl groups, e.g., a perfluorocyclobutane containing polymer.

A probabilistic digital signal processor using data from multiple instruments is described. In one example, a digital signal processor is integrated into a biomedical device. The processor is configured to: use a dynamic state-space model configured with a physiological model of a body system to provide a prior probability distribution function; receive sensor data input from at least two data sources; and iteratively use a probabilistic updater to integrate the sensor data as a fused data set and generate a posterior probability distribution function using all of: (1) the fused data set; (2) an application of Bayesian probability; and (3) the prior probability distribution function. The processor further generates an output of a biomedical state using the posterior probability function.

The present invention generally relates to methods of treating a surface of a substrate, and to the use of the method and resulting films, coatings and devices formed therefrom in various applications including but not limited to electronics manufacturing, printed circuit board manufacturing, metal electroplating, the protection of surfaces against chemical attack, the manufacture of localized conductive coatings, the manufacture of chemical sensors, for example in the fields of chemistry and molecular biology, the manufacture of biomedical equipment, and the like. In another aspect, the present invention provides a printed circuit board, a printed circuit board, comprising: at least one metal layer; a layer of organic molecules attached to the at least one metal layer; and an epoxy layeratop said layer of organic molecules.

The present invention relates to a process for grafting and growing a conductive organic film on(to) an electrically conductive or semiconductive surface in which the grafting and growing of the film are performed simultaneously by electro-reduction of a diazonium salt that is a precursor of the said film on(to) the said surface cathodically polarized at a potential greater than or equal, in absolute value, to the electro-reduction potential of the diazonium salt relative to a reference electrode. The invention finds an application especially in the protection of surfaces, the manufacture of localized conductive coatings, of chemical sensors in the fields of chemistry and molecular biology, the manufacture of biomedical equipment, etc.

A biomedical device assembly, such as a stent, for the targeted treatment of a tissue, such as the inhibition of restentosis. The stent is coated with an antigen, which is an example of a lock. The antigen can be bound by a labelled antibody, which is an example of a key and an effector. The antibody is preferably labelled with a radioactive source. According to one method of preparing the biomedical device assembly, after the stent has been placed in the blood vessel of the subject, the antibody is injected. The antibody then binds to the antigen on the stent, thereby localizing the radioactive source to the area to be treated, for example for restenosis. Other biomedical devices, such as a coil, an artificial valve or a vascular graft, could also be used in the place of the stent. The biomedical device could be placed in another biological passageway, such as the gastrointestinal tract, an airway or the genitourinary tract.

This invention includes a wettable biomedical device containing a high molecular weight hydrophilic polymer and a hydroxyl-functionalized silicone-containing monomer.

The present invention relates to a biomedical device with near field communication (NFC) function and a method thereof for user identification, biomedical data measurement, biomedical data upload / download, biomedical data management, and remote medical care, the biomedical device comprises: a measuring unit, a environment sensing unit, a data transforming unit, a micro control unit, a memory unit, a smart card unit, a display unit, and a near field communication unit, wherein by way of near field communication unit, the biomedical device is able to communicate with a portable device and a user individual information and the relative biomedical data thereof can be transmitted to the portable device, such that multi men are allowed for using the identical biomedical device and the situation about misrecording and misjudging of data would not be occurred; moreover, through the portable device, the biomedical data can be uploaded to a cloud server and a user history data and an optimized setting data for personalization biomedical device can be downloaded from the cloud server.

Intraocular lenses and methods producing the same are provided. The intraocular lens includes an optic and a haptic that are integrally formed together. The haptic has a polyimide coating. The polyimide coating promotes fibrosis in the surrounding eye tissue to enhance the anchoring of the IOL after it is implanted in an eye.

The invention relates to a method for manufacturing a titanium alloy having superelastic properties and / or shape memory for biomedical use, which comprises the steps of: preparing an ingot by melting the various metals that form the desired alloy in a vacuum; optionally homogenising the ingot in a vacuum by high-temperature annealing (higher than 900 DEG C); first quenching; mechanical shaping (rolling, drawing, machining or the like); heat treatment for redissolution in beta phase beyond the beta transus temperature (until a second temperature and then maintaining same for a certain time); and second quenching; characterised in that said heat treatment phase is carried out in a gaseous atmosphere and also constitutes a surface treatment suitable for forming on the surface a layer of nitride, carbonitride, oxide, oxynitride or the like.

The present invention includes an apparatus and method of making the apparatus that biomedical apparatus comprises a device adapted for use in a biomedical application that comprises a high entropy alloy comprising at least 5 elements.

A surface modified biomedical device is provided comprising a biomedical device having a coating on at least a portion thereof, the coating comprising a polymer or copolymer having one or more repeating units of the formula:wherein R independently is a C2-C20 hydrocarbon radical and n is an integer of 2 to 5000.

Bioscaffoldings formed of hydrogels that are crosslinked in situ in an infarcted region of the heart (myocardium) by a Michael's addition reaction or by a disulfide bond formed by an oxidative process are described. Each of the bioscaffoldings described includes hyaluronan as one of the hydrogel components and the other component is selected from collagen, collagen-laminin, poly-1-lysine, and fibrin. The bioscaffolding may further include an alginate component. The bioscaffoldings may have biofunctional groups such as angiogenic factors and stem cell homing factors bound to the collagen, collagen-laminin, poly-1-lysine, or fibrinogen hydrogel component. In particular, the biofunctional groups may be PR11, PR39, VEGF, bFGF, a polyarginine / DNA plasmid complex, or a DNA / polyethyleneimine (PEI) complex. Additionally, the hydrogel components may be injected into the infarct region along with stem cells and microspheres containing stem cell homing factors. The bioscaffolding may be formed on a stent or a cardiac medical device.

Biomedical devices such as contact lenses formed from a polymerization product of a mixture comprising (a) a multi-armed macromonomer comprising multiple side chains attached to a nucleus, wherein each side chain comprises a thio carbonyl thio fragment of the same or different reversible addition fragmentation chain transfer (“RAFT”) agent; and (b) one or more biomedical device-forming monomers are disclosed.

Compositions for inhibiting attachment of microorganisms to the surface of biomaterials include a polyether, such as a poloxamer. The compositions are especially useful for treating contact lenses to prevent bacterial attachment to the lens.

Biomedical devices such as contact lenses formed from a polymerization product of a mixture comprising (a) a hydrophilic polymer comprising one or more hydrophilic units and one or more thio carbonyl thio fragments of a reversible addition fragmentation chain transfer (“RAFT”) agent; and (b) one or more biomedical device-forming monomers are disclosed.

Methods and apparatus to form a biometric based information communication system are described. In some examples, the biometric based information communication system comprises biomedical devices with sensing means, wherein the sensing means produces a biometric result. In some examples the biometric based information communication system may comprise a user device such as a smart phone paired in communication with the biomedical device. A biometric measurement result may trigger a communication of a biometric based message. The system may operate in a vehicular environment.

Methods and apparatus to form a biometric based information communication system are described. In some examples, the biometric based information communication system comprises biomedical devices with sensing means, wherein the sensing means produces a biometric result. In some examples the biometric based information communication system may comprise a user device such as a smart phone paired in communication with the biomedical device. A biometric measurement result may trigger a communication of a biometric based information communication message.

A process for treating a silicone hydrogel biomedical device, especially an ophthalmic lens such as a contact lens, involves: immersing the silicone hydrogel biomedical device with a mixture of an organic solvent and a hydrophilic, polymeric material, for a sufficient time that the device is swollen in volume by at least 30%; and removing the organic solvent from the device while retaining at least a portion of the hydrophilic polymeric material therein.

A biomedical apparatus for pumping blood of a human or an animal patient through a secondary blood circuit is provided, including a blood pump (10), an inlet duct (11) and an outlet duct (12) for guiding blood of the patient to the blood pump (10) and back to the patient. The device further includes a measuring device (14) for measuring a physical parameter of the heart (2) or of a blood vessel, and a controller (13) for regulating the power of the blood pump (10). The measuring device (14) is adapted to be arranged inside the heart (2) or the blood vessel, and the controller is configured to determine an estimate for an inner volume of the heart (2) or of the blood vessel based on the physical parameter and is configured to regulate the power of the blood pump (10) depending on this estimate.

Biomedical devices such as contact lenses formed from a comprising a polymerization product of a mixture comprising an ethylenically unsaturated-containing non-amphiphilic macromonomer comprising hydrophilic units or hydrophobic units derived from a living radical polymerization of one or more ethylenically unsaturated hydrophilic monomers or one or more ethylenically unsaturated hydrophobic monomers are disclosed.

The present invention relates to a biomedical device capable of using an earphone and microphone plug to transmit data and a method for transmitting data, wherein the biomedical device comprises: a measuring unit, a micro-control unit, an earphone and microphone plug, a switch unit, a level shift unit, an amplifying unit, and a power management unit. By way of inserting the earphone and microphone plug into an earphone and microphone jack of a portable electronic device, the biomedical device is able to transmit data to the portable electronic device without passing the certification of the transmission format defined by a potable electronic device vender in advance. Moreover, through the method, a user can input biomedical data into the portable electronic device, so as to record and trace the daily biomedical data thereof; in addition, the biomedical data can be uploaded to a Cloud Database via the portable electronic device for a telemedicine management.

A patient table is used in combination with a biomedical apparatus such as a magnetic resonance imaging machine. The table includes a supporting surface sized to accommodate at least a part of the patient's body. At least one recess is formed in one or more areas of the supporting surface, these recesses being open at the peripheral edge of the supporting surface. The table is formed of first and second parts that can be angled relative to one another. The table can be swung horizontally to relative positions relative to the machine and locked in selected ones of the positions.