This invention relates to a method and a
system for generating a discriminatory
signal for a neurological condition, where at least one probe compound that has a neurophysiologic effect is provided.
Biosignal data are obtained from a subject based on
biosignal measurements obtained from
biosignal measuring device adapted for placement on a subject, wherein said
biosignal data are obtained posterior to the administering of said probe compound to the subject. Analogous biosignal reference data are provided for reference subjects in at least one reference group posterior to the administering of the probe compound, wherein the reference data are utilized for defining reference features having common characteristics between the reference subjects in the at least one reference group, wherein the reference data are processed for defining reference
posterior probability vectors for each respective reference subject, wherein each respective
posterior probability vector comprises particular feature or a
feature combination elements with probability values associated to said elements, the
posterior probability vectors resulting in a distribution of said features or feature combinations for said reference subjects. Subsequently, the biosignal data obtained from the subject are used for calculating analogues posterior
probability vector for said subject. The discriminatory
signal is then generated based on comparison between said posterior
probability vector for said subject and the distribution of said features or feature combinations.