105 results about "Artificial valve" patented technology

The invention discloses a TAVR postoperative blood flow parameter complementing method based on CT-MRI fusion, and belongs to the technical field of crossing of medical image processing and computational fluid mechanics. A CT valve frame registration technology is adopted, an invisible artificial valve leaflet three-dimensional structure is reconstructed through valve frame information in a CT image and is coupled with a dynamic heart model, a complete valve mechanical and functional simulation platform is constructed, the problem of an imaging blind area is solved, hemodynamic parameters of an inlet and an outlet of a postoperative area are further collected in combination with 4D Flow MRI, and the artificial valve leaflet three-dimensional structure is obtained. The blood flow conditions of the upstream and the downstream of the artificial valve area at each stage of contraction and relaxation of the TAVR postoperative part are comprehensively restored, the temporal-spatial resolution and the physical authenticity of the boundary condition in fluid-solid coupling simulation are greatly improved, and the more real passive response of the valve leaflet under the action of the blood flow is obtained; and a reliable basis is provided for quantitative and mechanical risk analysis of postoperative complications such as thrombosis, perivalvular leakage and valve leaflet fatigue.

The invention relates to an intracavity implantation system which comprises an intracavity prosthesis, the intracavity prosthesis has a radial expansion state and a radial contraction state, the intracavity prosthesis comprises a covered stent, a valve prosthesis and a flexible connecting pipe, the covered stent is of a tubular structure and comprises a main body section and a reducing section which are communicated with each other, and the valve prosthesis is arranged in the main body section. The main body section and the reducing section are arranged in the axial direction of the covered stent, the cross section area of the near end of the reducing section is smaller than that of the far end of the reducing section, the covered stent is further provided with a window penetrating through the side wall of the covered stent, and at least part of the area of the window is located in the reducing section; the valve prosthesis comprises a valve support and an artificial valve leaflet connected to the interior of the valve support. The flexible connecting pipe is of a tubular structure defined by a flexible film, the far end of the flexible connecting pipe is connected with the reducing section, the near end of the flexible connecting pipe is connected with the valve prosthesis, and the two axial ends of the flexible connecting pipe are communicated with the covered stent and the valve prosthesis respectively. In the implanting process of the endoluminal prosthesis, the relative position of the valve prosthesis and the covered stent can be adjusted according to the lumen structure, and the endoluminal prosthesis can better adapt to various lumen structures. In addition, due to the arrangement of the flexible connecting pipe, the risk that the far end of the valve prosthesis is driven to expand and deform due to expansion of the covered stent can be reduced, force generated in the expansion process of the valve prosthesis is not prone to being transmitted to the covered stent, and therefore the risk that coronary blood flow is blocked due to expansion of the near end of the covered stent can be reduced.

The invention provides an artificial heart valve thrombus risk assessment method and device. The thrombus risk assessment method for the artificial heart valve comprises the following steps: acquiring a physiological scene after the artificial heart is implanted into the artificial valve through a resistance characteristic parameter and an elastic expansion characteristic parameter; starting a pulsating pump to output a pulsating flow medium to the artificial heart in a physiological scene; capturing the motion trail of the fluorescent particles through a high-speed camera and obtaining the original data of the blood flow velocity at the downstream of the artificial valve; acquiring a fluid mechanics simulation parameter group according to the blood flow velocity original data; and inputting a pre-trained valvular thrombus random forest classifier according to the fluid mechanics simulation parameter group, and outputting a thrombus risk probability graph in the physiological scene. According to the method, the fluid mechanics simulation parameter group is calculated based on the instantaneous velocity vector field captured by the PIV and the space-time distribution information, the two-dimensional / three-dimensional thrombus risk probability graph is generated through the random forest classifier, the high-risk point coordinates are marked, and the thrombus probability and the thrombus position are accurately predicted.

The present invention discloses an artificial valve prosthesis, comprising a stent body and a leaflet assembly. The stent body includes a first stent and a second stent. The first stent has a connection end. Wherein, the second stent includes a plurality of stent rods, and the plurality of stent rods are respectively fixed to the connection end of the first stent. The leaflet assembly has a first leaflet fixing portion, and the leaflet assembly is fixed to the connection end of the first stent through the first leaflet fixing portion. Compared with the prior art framework structure composed of a plurality of closed geometric units, the second stent of the present invention is mainly composed of a plurality of stent rods, reducing the material of the stent body of the present invention, thereby reducing the cross-sectional area of the delivery device, and thus reducing the trauma area of the patient; in addition, the stent structure in the area sandwiched between the leaflet assembly and the second stent is relatively sparse, and blood is not easily deposited there, thus reducing the risk of thrombus formation.

The application provides a heart valve prosthesis and a preparation method thereof, the heart valve prosthesis comprising a stent and an integrated valve, the integrated valve comprising artificial valve leaves and a skirt, and the integrated valve being fixed to the stent by sewing threads; the preparation method comprises the following steps: obtaining an integrated valve material, and sequentially subjecting the integrated valve material to cutting, pre-shaping and folding processes, and finally sewing the folded integrated valve material on the stent to obtain the heart valve prosthesis. The application can minimize the damage to the valve, increase the durability of the valve, simplify the sewing process, reduce the production cost and improve the production efficiency.

The present disclosure relates to an auxiliary artificial valve for implantation in a blood vessel of a mammal patient. In the artificial valve there is provided a moving part moving between a closed position and an opened position, a casing to which the first moving part is movably attached and a resistance mechanism restricting the movement of the first moving part between the closed position and the opened position.

The utility model relates to a valve frame and an artificial heart valve. The valve frame can be switched between a radial compression structure and a radial expansion structure; each of an inflow row grid, an outflow row grid and a middle row grid of the valve frame comprises two rows of wave rods which are oppositely arranged and connected with each other, each row of wave rods comprises a plurality of supporting rods, and the opposite ends of every two adjacent supporting rods are connected at a joint part; each joint part comprises a solid part and a vacant part radially penetrating through the solid part, the opposite ends of the two adjacent supporting rods are smoothly connected with the solid part on the two sides of the vacant part, the vacant part is also in a smooth shape, and an opening of the vacant part corresponding to the wave crest of the wave rod faces the wave trough in the axial direction; the opening of the vacant part corresponding to the wave trough of the wave rod faces the wave crest in the axial direction; the joint part is used for helping each grid to uniformly deform in the structure conversion process of the valve frame; the width of the solid part is larger than or equal to the sum of two times of the width of the supporting rod and the width of the vacant part. The heart valve prosthesis comprises the valve frame, a covering film and at least two artificial valve leaflets capable of being opened and closed oppositely.

The present invention discloses a self-expanding atrioventricular valve prosthesis device, comprising: a main body portion, which is a frame structure, and the main body portion is implanted at the native valve annulus of the heart. The main body portion includes an inflow section, an outflow section and a transition section. The inflow section is located at the atrial end, the outflow section is located at the ventricular end, and the transition section is located between the inflow section and the outflow section; it further includes at least one artificial valve leaf, which is fixed to the transition section of the main body portion, and the artificial valve leaf is provided with a connecting portion; it further includes a chordae tendineae portion, one end of which is fixed, and the other end is connected to the artificial valve leaf through the connecting portion. The present invention restricts the movement range of the artificial valve leaf through the chordae tendineae portion, and the connecting portion prevents the chordae tendineae portion from tearing and stress concentration on the valve leaf, thereby increasing the durability of the artificial valve leaf.

The utility model relates to the field of interventional therapy, and discloses a vena cava interventional valve. The vena cava interventional valve comprises a body support, the body support comprises an upper cone part, a barrel part and a lower cone part, and the upper cone part and the lower cone part are arranged at the two ends of the barrel part respectively; the fixing piece is arranged at the joint of the upper cone part and the barrel part; the covering film is arranged on the outer side of the body stent; and the artificial valve leaflet is arranged in the barrel part of the body bracket. The conveying size of an existing inferior vena cava filter is small and is only 6F, and the inferior vena cava filter is improved on the basis of the basic structure of the inferior vena cava filter, so that the inferior vena cava filter has the same small conveying size and fixing efficiency; by means of the fixing piece, positioning can be accurately and easily achieved in the valvular operation, and the pressing difficulty of the surgical operation is reduced; and the valve can be completely recovered before being completely released, so that the safety of the operation is improved.

The application provides a kind of artificial valve fatigue life evaluation method, system, equipment and medium, method includes: obtaining the stress load spectrum of artificial valve surface fatigue failure risk point in several cardiac cycles;Obtain the load order segment number of the stress load spectrum of any cardiac cycle after the load trend tends to be stable, the alternating stress, average stress and cycle number of each load order segment;Calculate the fatigue failure cycle number of the artificial valve material standard sample corresponding to each load order segment;The ratio of cycle number and fatigue failure cycle number under each load order segment is calculated to obtain the fatigue damage under the load order segment;The sum of fatigue damage under all load orders is obtained, and its reciprocal is the expected fatigue life.The application has the advantages of short time consumption, low cost, low difficulty, high accuracy, high precision and less limitation.

Devices, systems, and methods for prosthetic valves are described. Prosthetic valve embodiments may be directed to sealing flow at an implantation site, which may include a native valve. Embodiments may be configured to conform to the shape of the native valve, which may be a non-circular shape. Embodiments may include a frame having portions joined together by one or more revolute joints. Embodiments may include a crescent-shaped frame. Embodiments may include a frame structure having an integral portion. Embodiments may include a portion of a prosthetic valve having a micropattern applied to the prosthetic valve. One or more microbeads may be utilized in embodiments. Prosthetic valve structures utilizing support rings may be provided.

The invention provides an artificial valve leaflet connecting structure and method in the technical field of medical instruments, the artificial valve leaflet connecting structure comprises an artificial valve leaflet, lugs, a connecting piece, a support and a suture line, the lugs and creases are arranged at the two ends of the artificial valve leaflet, and the lugs at the two ends are folded along the creases. The two ends of the artificial valve leaflets are aligned and tightly attached to each other side by side, the lugs comprise the first lug and the second lug, and the first lug and the second lug are arranged along the creases in a folded mode. According to the valve leaflet connecting method, one end of the connecting piece is connected with the second folded convex lug in a bent and embedded mode, the other end of the connecting piece is connected to the support in a bent and buckled mode, the suture line sequentially penetrates through the connecting piece, the convex lug and the end of the artificial valve leaflet, and the connecting piece, the convex lug, the end of the artificial valve leaflet and the support are fixedly connected through the suture line; the connecting structure is used for achieving firm connection between the ends of the adjacent artificial valve leaflets, so that the artificial valve leaflets are stably opened and closed, and the probability that blood flows between the ends of the adjacent artificial valve leaflets to generate a reflux phenomenon is reduced.

A method and an assembly for attaching a radiopaque marker to an attachment member of an artificial valve are disclosed. As an example, an artificial heart valve can include a frame including struts forming cells of the frame, at least one commissure comprising an attachment member and commissure tabs of two adjacent valve leaflets coupled thereto, an attachment member disposed across the cells of the frame and attached to the struts defining the cells, and a radiopaque marker suspended within the cell and suspended relative to the attachment member by suture threads. The suture threads extend from a first portion of the attachment member, through one or more openings of the marker, to a second portion of the attachment member, and the suture threads form two knots at the second portion on opposite sides of the marker such that the suture threads form an X-pattern that does not cross through the marker and across the attachment member.

The present invention discloses a stent delivery system assembly and an artificial valve delivery system assembly, comprising a radially expandable stent, a delivery device and at least one set of pin connection wires; at least one connection hole is provided on the stent in the circumferential direction; the pin connection wire comprises a head wire and at least one first connection wire, the first connection wire is connected to the delivery device and has a wire hole, after the wire hole passes through the connection hole, the first connection wire is bent at the connection hole, and the wire hole extends circumferentially around the stent for an adjacent first connection wire or the head wire to pass through; the head wire has a first end and a second end, the first end of the head wire is connected to the delivery device, and the second end of the head wire is detachably connected to the delivery device after passing through the connection hole and the wire hole of the first connection wire. The wire control method of the present invention has a short wire withdrawal path, small resistance, and simple wire withdrawal steps, simplifies the structure of the delivery device, and reduces the surgical difficulty at the same time.

The present invention provides a delivery system for an artificial valve, comprising an outer tube, an inner tube, an inflatable balloon, a first stopper and a second stopper. Both the first stopper and the second stopper include a fixing portion and a stopping portion. The stopping portion is a circumferentially closed annular structure. The fixing portion is connected to the inner tube. A first fluid passage or a second fluid passage is provided on the side wall of the first stopper; a first fluid passage is provided on the side wall of the second stopper; the first fluid passage axially penetrates through the stopping portion in the inner tube; the second fluid passage axially penetrates from one end of the stopping portion of the first stopper away from the fixing portion to the end of its fixing portion away from the stopping portion in the inner tube; the ends of the two stopping portions can axially limit the artificial valve. The present invention can make the expansion medium flow more smoothly in the initial stage of the inflation of the inflatable balloon, which is beneficial to the rapid progress of interventional treatment and better prevents the axial displacement of the artificial valve during the inflation of the inflatable balloon.

The invention relates to the field of medical instruments, in particular to a valve prosthesis for replacing a mitral valve, which comprises an outer stent and an inner stent, the outer stent is provided with a fabric layer, the inner stent is provided with an artificial valve leaflet, the outer stent comprises an anchoring section and a self-adaptive section, the anchoring section comprises a grid-type stent and an anchoring assembly, the anchoring assembly comprises a cannula part, a puncture part and a control wire, and the self-adaptive section is provided with a control wire. Barbs and a connecting hole are arranged on the puncture part, the puncture part is arranged in the sleeve part, the puncture part is fixedly connected with the sleeve part, an opening is formed in the sleeve part, and when the control wire penetrates through the connecting hole and is clamped with the other end of the sleeve part in a matched mode to achieve detachable connection, the barbs are limited in the sleeve part; when the control wire is pulled out of the connecting hole, the barbs extend out of the opening and penetrate through the fabric layer to be pricked into the heart tissue; release of the barbs on the puncture part is controllable, an operator can release the stent firstly and then adjust the stent to an ideal position, and then the barbs are further released to anchor the stent.

The present invention relates to an implantable artificial device, such as an artificial heart valve, and to a mounting configuration and method for attaching a soft component, such as a valve leaflet or skirt, to the frame of such an artificial valve. [Solution] The valve leaflets are connected to the struts of the frame via primary sutures, which are passed in an in-and-out pattern along the cusp end portion of the valve leaflets, and the secondary sutures are passed around the struts through the primary sutures and have a plurality of self-tightening structures configured to contract on the struts under tension.

The present application relates to a kind of artificial heart valve stents and artificial heart valve.The artificial heart valve stent includes inner support and outer support.Inclination from inflow end to outflow end, first portion and second portion are included in sequence in inner support, the radial dimension of first portion is greater than the radial dimension of second portion, at least a portion of second portion is nested in outer support, and at least a portion of first portion extends to inflow end relative to outer support, and the portion of first portion extending to inflow end relative to outer support covers flow blocking film.The artificial heart valve includes the artificial heart valve stent and artificial valve leaflet fixedly connected in inner support.The artificial heart valve stent and artificial heart valve can reduce the risk of paravalvular leakage while being stably positioned in heart.

The utility model discloses a heart valve supporting module, which relates to the technical field of medical treatment, aims to solve the technical problem that a bioprosthetic valve is easy to decline and cannot be normally opened and closed, and comprises a suture ring, the suture ring and a heart valve ring of a patient are sutured and fixed, and a plurality of valve frames are inserted into the lower half part of the suture ring in an inward inclined manner. An artificial valve cord is arranged between the outer ring of the suture ring and the outer sides of the valve frames, the artificial valve cord is connected with the bioprosthetic valve, and a plurality of stabilizing structures are arranged between the artificial valve cord and the valve frames. The outer arc side of the valve frame is used for restraining the edge of the artificial valve cord, and the artificial valve cord is connected with the bioprosthetic valve, so that contraction of the bioprosthetic valve is indirectly limited, excessive contraction of the bioprosthetic valve is effectively avoided, a stable structure is matched, excessive expansion of the bioprosthetic valve can be effectively avoided, and the bioprosthetic valve is stable in structure. The risk that the valve cannot be normally opened and closed due to excessive expansion of the periphery of the valve is reduced, the service life of the bioprosthetic valve is prolonged, and the possibility of secondary operation is reduced.

Provided are an artificial intelligence AI-based simulation device and method for supporting procedure planning in transcatheter aortic valve implantation. The device receives patient-specific medical images, such as computed tomography data, and generates a three-dimensional (3D) model of the aortic root and native valve. An artificial valve is virtually inserted into the 3D model, and the virtual implantation model is automatically converted into mesh data suitable for Computational Fluid Dynamics (CFD) and Fluid-Structure Interaction (FSI) analysis. The processor performs CFD / FSI simulations to evaluate hemodynamic changes, structural stresses, and potential device-tissue interactions. Based on the analysis, the system outputs predicted risks of procedure-related complications (including coronary obstruction, annular rupture, paravalvular leakage, and valve deformation) and provides guideline data for selecting valve size, implantation depth, and insertion angle. The disclosed device and method enable accurate, patient-specific prediction and visualization, thereby assisting clinicians in establishing safe and optimized TAVI procedure plans.

The invention relates to the technical field of medical data processing, and discloses a heart valve replacement postoperative hemodynamic simulation and curative effect evaluation processing system which comprises the steps that a preset standard artificial valve three-dimensional geometric model is used for replacing a valve area distorted due to metal artifacts in computed tomography data so as to generate a static computational domain grid, the method comprises the following steps: adding a time-varying quantity source item resistance coefficient in a Navier Stokes equation according to a cardiac cycle sequential logic, simulating a valve leaflet opening and closing physical effect under a static grid by adjusting a spatial unit fluid impedance attribute, and resolving a flow field, and establishing a virtual motion mechanism based on a momentum source item to replace complex dynamic grid reconstruction; and the numerical stability and clinical treatment time efficiency of simulation calculation are improved while the geometric boundary fidelity is ensured.

The present invention relates to the field of medical devices, and in particular to a prosthetic system with a positioning mechanism, comprising an artificial valve leaflet, an anchoring assembly, a guiding mechanism and a positioning mechanism; the positioning mechanism is provided with a plurality of positioning components, the artificial valve leaflet is detachably connected to the positioning component, and the guiding mechanism is connected to the anchoring assembly; at the same time, the guiding mechanism is detachably connected to the positioning component; the anchoring assembly can reach a designated position by relying on the traction between the guiding mechanism and the positioning component; the present invention detachably connects the anchoring mechanism and the positioning mechanism, and the force generated by the anchoring mechanism during the guiding needle insertion process will not act on the artificial valve leaflet, thereby avoiding wrinkling of the soft artificial valve leaflet during the needle insertion process, ensuring its anchoring effect, and having good clinical significance.

The present disclosure relates to an artificial valve that includes an information indicator that can indicate appropriate information related to a previously implanted artificial valve. Such an information indicator may be formed internally within a relatively wide support post of a mechanically expandable artificial valve, or may be formed externally along a support post of a mechanically expandable artificial valve or a vertical strut of a balloon-expandable artificial valve.

The invention discloses an artificial heart valve with a clamping structure. The artificial heart valve comprises a first valve seat body, a second valve seat body and an artificial valve leaflet, the second valve seat body is arranged on the outer side of the first valve seat body, and the artificial valve leaflet is arranged between the first valve seat body and the second valve seat body; the second valve seat body is provided with a parting line, the midpoint of the parting line intersects with the central axis of the second valve seat body, and the parting line divides the second valve seat body into two halves. The overall symmetry of the artificial valve is improved, meanwhile, the influence of traditional suture on the peripheral suture edge part of the artificial valve leaflet is avoided, and the service life of the artificial heart valve is prolonged. Meanwhile, the replicability and quantitative production of the whole structure of the artificial valve are guaranteed, and the production efficiency is improved.

The application belongs to the field of medical devices, and particularly relates to an implant device system with a reduced loading tube diameter, comprising an inner tube, an outer sheath tube, an implant device and an anchoring mechanism; the implant device comprises artificial valve leaflets; when preloaded, the implant device and the anchoring mechanism are arranged between the inner tube and the outer sheath tube, and the anchoring mechanism is arranged in axial non-overlapping mode with the artificial valve leaflets; and after the implant device reaches the expected anchoring position, the anchoring mechanism can reach the designated position according to a predetermined route; when preloaded, the distal end of the anchoring mechanism is located on the proximal side of the artificial valve leaflets and does not overlap with the artificial valve leaflets, so that the loading tube diameter of the delivery system is reduced as much as possible, and damage to the blood vessels of a patient during surgery is avoided.

A prosthetic valve (22, 222) configured for transcatheter implantation is provided, the prosthetic valve (22, 222) comprising a prosthetic valve frame and a plurality of prosthetic leaflets (140). The prosthetic valve frame includes a plurality of struts and is shaped to define a plurality of intermediate nodes (30, 230) that are intermediate proximal and distal ends (26, 28) of the prosthetic valve frame. A part of the plurality of struts is an intermediate strut (40). Each intermediate node (30, 230) has at least four struts extending therefrom, including (a) a pair of distally extending two struts (44) of the at least four struts, and (b) a pair of proximally extending two struts (46) of the at least four struts. Other embodiments are also described.

The invention relates to an artificial cuspid valve supporting structure and an artificial cuspid valve device. The artificial cuspid valve supporting structure comprises a cuspid valve supporting body and a supporting part. The sharp valve supporting body is used for being fixed to the inner wall of a native valve ring, a blood flow channel is constructed in the sharp valve supporting body, and the blood flow channel is used for being communicated with an atrium and a ventricle and used for containing an artificial valve leaflet; one end of the supporting part is connected with the cuspid valve supporting body, and the other end of the supporting part is used for elastically abutting against the inner wall of the atrium so as to apply acting force towards the ventricle to the cuspid valve supporting body. According to the application, one end of the supporting part is connected with the cusp valve supporting body, and the other end of the supporting part is used for elastically abutting against the inner wall of the atrium to apply the acting force towards the ventricle to the cusp valve supporting body, so that the supporting part provides stable supporting force for the cusp valve supporting body to prevent the cusp valve supporting body from being impacted to the atrium; and the stability of connection between the sharp valve supporting body and the inner wall of the native valve ring is improved.

The embodiment of the present application provides an artificial valve delivery device, which includes a valve release adjustment component, a fixing seat, and a first adjustment mechanism, wherein the valve release adjustment component includes a base, the fixing seat is mounted on the base, and the first adjustment mechanism is mounted on the base and is mutually limited with the fixing seat in a first direction, and is used to adjust the movement of the valve release adjustment component relative to the fixing seat in the first direction, wherein a first limiting portion is provided on the base, and the first limiting portion is used to limit the fixing seat in the first direction. The present application can improve the maneuverability of the artificial valve delivery device, so that the positioning of the valve release adjustment component before releasing the valve and the position of the released valve are more accurate, which is conducive to making the surgical effect of implanting an artificial valve higher, and can control the movement distance of the valve release adjustment component so that the valve release adjustment component does not extend too far into the heart tissue, which can improve the safety of the valve implantation surgery.

A prosthetic valve includes a flexible frame disposed along a frame axis and deformable about the frame axis. The frame includes a first end, a second end disposed opposite the first end, and a network of interconnected struts defining a plurality of cells. A first circuit is mounted on the frame. The first circuit includes: a first inductor coil attached to and tracking a first subset of the struts such that the first inductor coil outlines a first subset of the plurality of cells; and a first sensor in electrical communication with the first inductor coil. The first sensor is configured to sense a physical parameter and generate a signal representative of the physical parameter.

To provide an artificial valve that can be delivered laterally. [Solution] A laterally deliverable artificial valve comprising a valve frame and a flow control component fitted within a central channel of the valve frame and configured to allow blood flow through the central channel in a direction along the central axis of the artificial valve, wherein the actuator is detachably attached to a proximal inferior annular anchor element of the valve frame.