35 results about "Artificial valve" patented technology

The invention relates to an intracavity implantation system which comprises an intracavity prosthesis, the intracavity prosthesis has a radial expansion state and a radial contraction state, the intracavity prosthesis comprises a covered stent, a valve prosthesis and a flexible connecting pipe, the covered stent is of a tubular structure and comprises a main body section and a reducing section which are communicated with each other, and the valve prosthesis is arranged in the main body section. The main body section and the reducing section are arranged in the axial direction of the covered stent, the cross section area of the near end of the reducing section is smaller than that of the far end of the reducing section, the covered stent is further provided with a window penetrating through the side wall of the covered stent, and at least part of the area of the window is located in the reducing section; the valve prosthesis comprises a valve support and an artificial valve leaflet connected to the interior of the valve support. The flexible connecting pipe is of a tubular structure defined by a flexible film, the far end of the flexible connecting pipe is connected with the reducing section, the near end of the flexible connecting pipe is connected with the valve prosthesis, and the two axial ends of the flexible connecting pipe are communicated with the covered stent and the valve prosthesis respectively. In the implanting process of the endoluminal prosthesis, the relative position of the valve prosthesis and the covered stent can be adjusted according to the lumen structure, and the endoluminal prosthesis can better adapt to various lumen structures. In addition, due to the arrangement of the flexible connecting pipe, the risk that the far end of the valve prosthesis is driven to expand and deform due to expansion of the covered stent can be reduced, force generated in the expansion process of the valve prosthesis is not prone to being transmitted to the covered stent, and therefore the risk that coronary blood flow is blocked due to expansion of the near end of the covered stent can be reduced.

The application provides a heart valve prosthesis and a preparation method thereof, the heart valve prosthesis comprising a stent and an integrated valve, the integrated valve comprising artificial valve leaves and a skirt, and the integrated valve being fixed to the stent by sewing threads; the preparation method comprises the following steps: obtaining an integrated valve material, and sequentially subjecting the integrated valve material to cutting, pre-shaping and folding processes, and finally sewing the folded integrated valve material on the stent to obtain the heart valve prosthesis. The application can minimize the damage to the valve, increase the durability of the valve, simplify the sewing process, reduce the production cost and improve the production efficiency.

Devices, systems, and methods for prosthetic valves are described. Prosthetic valve embodiments may be directed to sealing flow at an implantation site, which may include a native valve. Embodiments may be configured to conform to the shape of the native valve, which may be a non-circular shape. Embodiments may include a frame having portions joined together by one or more revolute joints. Embodiments may include a crescent-shaped frame. Embodiments may include a frame structure having an integral portion. Embodiments may include a portion of a prosthetic valve having a micropattern applied to the prosthetic valve. One or more microbeads may be utilized in embodiments. Prosthetic valve structures utilizing support rings may be provided.

The present invention relates to an implantable artificial device, such as an artificial heart valve, and to a mounting configuration and method for attaching a soft component, such as a valve leaflet or skirt, to the frame of such an artificial valve. [Solution] The valve leaflets are connected to the struts of the frame via primary sutures, which are passed in an in-and-out pattern along the cusp end portion of the valve leaflets, and the secondary sutures are passed around the struts through the primary sutures and have a plurality of self-tightening structures configured to contract on the struts under tension.

The present application relates to a kind of artificial heart valve stents and artificial heart valve.The artificial heart valve stent includes inner support and outer support.Inclination from inflow end to outflow end, first portion and second portion are included in sequence in inner support, the radial dimension of first portion is greater than the radial dimension of second portion, at least a portion of second portion is nested in outer support, and at least a portion of first portion extends to inflow end relative to outer support, and the portion of first portion extending to inflow end relative to outer support covers flow blocking film.The artificial heart valve includes the artificial heart valve stent and artificial valve leaflet fixedly connected in inner support.The artificial heart valve stent and artificial heart valve can reduce the risk of paravalvular leakage while being stably positioned in heart.

Provided are an artificial intelligence AI-based simulation device and method for supporting procedure planning in transcatheter aortic valve implantation. The device receives patient-specific medical images, such as computed tomography data, and generates a three-dimensional (3D) model of the aortic root and native valve. An artificial valve is virtually inserted into the 3D model, and the virtual implantation model is automatically converted into mesh data suitable for Computational Fluid Dynamics (CFD) and Fluid-Structure Interaction (FSI) analysis. The processor performs CFD / FSI simulations to evaluate hemodynamic changes, structural stresses, and potential device-tissue interactions. Based on the analysis, the system outputs predicted risks of procedure-related complications (including coronary obstruction, annular rupture, paravalvular leakage, and valve deformation) and provides guideline data for selecting valve size, implantation depth, and insertion angle. The disclosed device and method enable accurate, patient-specific prediction and visualization, thereby assisting clinicians in establishing safe and optimized TAVI procedure plans.

The invention relates to the technical field of medical data processing, and discloses a heart valve replacement postoperative hemodynamic simulation and curative effect evaluation processing system which comprises the steps that a preset standard artificial valve three-dimensional geometric model is used for replacing a valve area distorted due to metal artifacts in computed tomography data so as to generate a static computational domain grid, the method comprises the following steps: adding a time-varying quantity source item resistance coefficient in a Navier Stokes equation according to a cardiac cycle sequential logic, simulating a valve leaflet opening and closing physical effect under a static grid by adjusting a spatial unit fluid impedance attribute, and resolving a flow field, and establishing a virtual motion mechanism based on a momentum source item to replace complex dynamic grid reconstruction; and the numerical stability and clinical treatment time efficiency of simulation calculation are improved while the geometric boundary fidelity is ensured.

The invention discloses an artificial heart valve with a clamping structure. The artificial heart valve comprises a first valve seat body, a second valve seat body and an artificial valve leaflet, the second valve seat body is arranged on the outer side of the first valve seat body, and the artificial valve leaflet is arranged between the first valve seat body and the second valve seat body; the second valve seat body is provided with a parting line, the midpoint of the parting line intersects with the central axis of the second valve seat body, and the parting line divides the second valve seat body into two halves. The overall symmetry of the artificial valve is improved, meanwhile, the influence of traditional suture on the peripheral suture edge part of the artificial valve leaflet is avoided, and the service life of the artificial heart valve is prolonged. Meanwhile, the replicability and quantitative production of the whole structure of the artificial valve are guaranteed, and the production efficiency is improved.

The application belongs to the field of medical devices, and particularly relates to an implant device system with a reduced loading tube diameter, comprising an inner tube, an outer sheath tube, an implant device and an anchoring mechanism; the implant device comprises artificial valve leaflets; when preloaded, the implant device and the anchoring mechanism are arranged between the inner tube and the outer sheath tube, and the anchoring mechanism is arranged in axial non-overlapping mode with the artificial valve leaflets; and after the implant device reaches the expected anchoring position, the anchoring mechanism can reach the designated position according to a predetermined route; when preloaded, the distal end of the anchoring mechanism is located on the proximal side of the artificial valve leaflets and does not overlap with the artificial valve leaflets, so that the loading tube diameter of the delivery system is reduced as much as possible, and damage to the blood vessels of a patient during surgery is avoided.

The invention relates to an artificial cuspid valve supporting structure and an artificial cuspid valve device. The artificial cuspid valve supporting structure comprises a cuspid valve supporting body and a supporting part. The sharp valve supporting body is used for being fixed to the inner wall of a native valve ring, a blood flow channel is constructed in the sharp valve supporting body, and the blood flow channel is used for being communicated with an atrium and a ventricle and used for containing an artificial valve leaflet; one end of the supporting part is connected with the cuspid valve supporting body, and the other end of the supporting part is used for elastically abutting against the inner wall of the atrium so as to apply acting force towards the ventricle to the cuspid valve supporting body. According to the application, one end of the supporting part is connected with the cusp valve supporting body, and the other end of the supporting part is used for elastically abutting against the inner wall of the atrium to apply the acting force towards the ventricle to the cusp valve supporting body, so that the supporting part provides stable supporting force for the cusp valve supporting body to prevent the cusp valve supporting body from being impacted to the atrium; and the stability of connection between the sharp valve supporting body and the inner wall of the native valve ring is improved.

A prosthetic valve includes a flexible frame disposed along a frame axis and deformable about the frame axis. The frame includes a first end, a second end disposed opposite the first end, and a network of interconnected struts defining a plurality of cells. A first circuit is mounted on the frame. The first circuit includes: a first inductor coil attached to and tracking a first subset of the struts such that the first inductor coil outlines a first subset of the plurality of cells; and a first sensor in electrical communication with the first inductor coil. The first sensor is configured to sense a physical parameter and generate a signal representative of the physical parameter.

To provide an artificial valve that can be delivered laterally. [Solution] A laterally deliverable artificial valve comprising a valve frame and a flow control component fitted within a central channel of the valve frame and configured to allow blood flow through the central channel in a direction along the central axis of the artificial valve, wherein the actuator is detachably attached to a proximal inferior annular anchor element of the valve frame.

Artificial heart valves, their manufacture, and methods of use are described. Generally, artificial heart valves can be deployed to replace or supplement defective heart valves in a patient. These artificial heart valves can comprise a frame with an inner skirt and leaflets. These inner skirt and leaflets can be generated from regenerative tissue to allow integration of the tissue with the body of a patient, while the frame can be generated from bioabsorbable material to allow dissolution of the frame over time. This combination of materials may allow for the artificial valve to grow with a patient and avoid costly and potentially dangerous replacement for patients receiving artificial valves.

The invention discloses an integrated heart valve stent, and relates to the field of heart valve stents. The integrated heart valve stent comprises a main stent body and a plurality of sets of positioning pieces used for being inserted into the sinus floor of a heart valve. A plurality of groups of supporting pieces which are connected in sequence are arranged in the main body bracket, the supporting pieces are connected with the main body bracket, and each group of supporting pieces comprises a first supporting rod and a second supporting rod. In the same group of supporting pieces, the first supporting rods and the second supporting rods are connected in a crossed mode. The positioning piece comprises a left positioning rod and a right positioning rod, the fixed end of the left positioning rod and the fixed end of the right positioning rod are arranged at the connecting positions of the supporting pieces, and the connecting positions of the left positioning rod and the right positioning rod are different. And the free end of the left positioning rod is detachably connected with the free end of the right positioning rod. Through the arrangement, direct contact between the original valve leaflet and the artificial valve leaflet is effectively prevented, and the risk that the original valve leaflet invades the artificial valve leaflet is reduced.

An artificial heart valve with a sleeve structure and a preparation method thereof, comprising a first valve seat body, a second valve seat body and artificial valve leaflets; the second valve seat body is sleeved outside the first valve seat body, the artificial valve leaflets are arranged between the first valve seat body and the second valve seat body, the artificial valve leaflets are composed of three equal and same valve leaflets and one covering film, and free end edges of the three valve leaflets are in a wave shape and gradually change in thickness from roots to edges. The sleeve structure improves overall stability and assembly precision, the wave-shaped valve leaflet edges optimize the sealing performance and anti-reflux effect of the artificial valve leaflets, the gradually changing valve leaflet thickness balances the structural strength and flexibility, the bionic microtexture improves the hemodynamics and antithrombotic performance, and when the artificial heart valve is prepared, the femtosecond laser direct writing is adopted to ensure the precision and consistency of the bionic microtexture.

The application provides an artificial valve release device, which comprises a mounting piece and a supporting arm, the mounting piece is connected with an artificial valve leaf, the supporting arm is provided with a limiting part for limiting the mounting piece, a puncture tube is arranged in the supporting arm, an anchor and a push rod are arranged in the puncture tube, the push rod is located at the proximal end of the anchor, the puncture tube is used for puncturing the artificial valve leaf and a native valve, after the puncture is completed, the puncture tube is withdrawn into a puncture channel of the supporting arm, in the process of withdrawing the puncture tube into the puncture channel, the push rod abuts against the anchor to prevent the anchor from being withdrawn with the puncture tube, and then the anchor is penetrated out of the puncture tube, the anchor is then connected with the artificial valve leaf and the native valve after being penetrated out of the puncture tube, the mounting piece is then separated from the limiting part after being fixedly connected, the artificial valve leaf is also separated from the supporting arm along with the mounting piece, and then the artificial valve leaf and the native valve are fixedly connected, so that the technical problem that the artificial valve is difficult to be released from the device and connected to the native valve is solved.

The application discloses a kind of valve conduit and forming method, including artificial blood vessel formed by using biological material, the artificial blood vessel has sewing part for being sutured with artificial valve at one end;Artificial valve has sewing edge for being sutured with artificial blood vessel;Sewing part is covered and arranged on the upper surface of sewing edge from the outer edge of sewing edge to the root of sewing edge, and is sutured with sewing edge between sewing edge outer edge and root position respectively.Sewing part is conveniently realized conformal fit and covered arrangement on the surface of sewing edge by using the elasticity and flexibility of artificial blood vessel of biological material, and by being sutured with sewing edge and sewing part at the root of sewing edge and the outer edge of sewing edge respectively, not only solve the connection problem between artificial blood vessel of biological material and artificial valve, and the problem of leakage easily occurring at connection position is well solved.

Modular prosthetic valves are disclosed that may support a customized number of leaflets, e.g., four or more leaflets carried by a support structure, such as a frame or stent, which may be used to replace diseased mitral, aortic, tricuspid, or pulmonary valves.

The invention provides a valve prosthesis which comprises a valve frame, a film covering the valve frame and at least two artificial valve leaflets capable of being opened and closed oppositely, and the artificial valve leaflets are fixedly connected to the valve frame or / and the film. The valve frame comprises a valve frame main body and a plurality of loading pieces connected to the valve frame main body; the loading piece comprises a first loading section and a second loading section, a first loading part is arranged on the first loading section, a second loading part is arranged on the second loading section, the first loading part is arranged at the first end of the valve frame main body and can be loaded by a valve conveying device, and the second loading part is arranged at the second end of the valve frame main body and can be loaded by a valve conveying device. The second loading portion is disposed at a second end of the valve frame body opposite the first end and is loadable by a valve delivery device. Compared with the prior art, the application range of the valve prosthesis is widened.

The invention discloses an artificial heart valve with a sleeve type structure and a preparation method thereof. The artificial heart valve comprises a first valve seat body, a second valve seat body and an artificial valve leaflet, the second valve seat body is arranged on the outer side of the first valve seat body in a sleeving mode, the artificial valve leaflet is arranged between the first valve seat body and the second valve seat body, and the artificial valve leaflet is composed of three identical valve leaflet bodies with the same size and one coating film. The edges of the free ends of the three valve leaflets are wavy, and the thicknesses of the three valve leaflets are gradually changed from the roots to the edges. The integral stability and assembly precision are improved through the sleeve type structure, the sealing performance and the anti-reflux effect of the artificial valve leaflet are optimized through the wave-shaped valve leaflet edge, the structural strength and flexibility are balanced through gradual change of the valve leaflet thickness, the hemodynamics and the anti-thrombus performance are improved through bionic micro-textures, and when the artificial heart valve is prepared, the artificial valve leaflet can be used for preparing the artificial heart valve. Femtosecond laser direct writing is adopted, so that the precision and consistency of bionic micro textures are guaranteed.

Provided are systems and methods for wireless, LCR-based, passive sensor systems for catheter or other implantable deployment using collapsible electromechanics. Each sensor system includes a deformable coil and a capacitive pressure sensor, collectively forming a LCR circuit having a self-resonant frequency. Multiple sensor systems may be implanted in a collapsible artificial valve to non-invasively detect the status of the collapsible artificial valve. Specifically, when the collapsible artificial valve is implanted in a mammal subject, antennas may be disposed on the skin of the mammal subject to wirelessly measure the self-resonant frequencies of the LCR circuits of the sensor systems. Thus, the blood pressure of the mammal subject may be calculated based on the self-resonant frequencies measured by the antenna, and the status of the collapsible artificial valve may be determined based on the blood pressure.

The application belongs to the field of medical devices, and particularly relates to a valve prosthesis for treating a tricuspid valve, comprising a stent and artificial valve leaflets, wherein the stent comprises a braided ring and a valve sewing segment, the braided ring is connected with the valve sewing segment, the braided ring comprises a ventricular part, an annulus part and an atrial part, the atrial part comprises a septal annulus segment, an anterior annulus segment and a posterior annulus segment, the anterior annulus segment and the posterior annulus segment are both provided with close-fitting structures, the close-fitting structures enable the edges of the anterior annulus segment and the posterior annulus segment to be pressed towards the proximal end direction, the edges of the anterior annulus segment and the posterior annulus segment are in a wavy shape, the edges of the middle region of the anterior annulus segment and the middle region of the posterior annulus segment are at wave trough positions, the edges of the end of the anterior annulus segment and the end of the posterior annulus segment are at wave crest positions, and when the native valve is opened and closed, the edge height of the middle region of the anterior annulus segment and the edge height of the middle region of the posterior annulus segment are always lower than the edge height of the end of the anterior annulus segment and the edge height of the end of the posterior annulus segment.

The invention belongs to the technical field of medical instruments, and particularly relates to a valve leaflet enhancing device which comprises a catheter component, a driving mechanism, a clamping assembly, an artificial valve leaflet and a puncture assembly, the driving mechanism comprises a handle assembly and a driving assembly, the clamping assembly comprises a first clamping arm and a second clamping arm, and the first clamping arm is provided with a first clamping face; the second clamping arm is provided with a second clamping face matched with the first clamping face, the artificial valve leaflet is detachably connected to the second clamping arm, and the puncture assembly comprises a first puncture structure and a second puncture structure. When the second clamping arm is closed, the first puncture structure is in puncture connection with the middle area of the native valve leaflet and the middle area of the artificial valve leaflet, and then when the second clamping arm, the artificial valve leaflet and the native valve leaflet are opened together, the second puncture structure is in puncture connection with the side edge area, located on at least one side of the two sides of the second clamping arm, of the native valve leaflet and the artificial valve leaflet. Therefore, the problem that blood regurgitation is caused due to the fact that the side edge areas of the original valve leaflet and the artificial valve leaflet cannot be stably attached after an existing heart valve leaflet repairing operation is solved.

The present application relates to a kind of delivery device for delivering artificial valve, the delivery device includes: covering body, is tubular and is used to cover artificial valve, the covering body is equipped with the flow-through hole being communicated with its inner cavity and the outside world;Inner sheath, can slide relative to the covering body;And sheath core mechanism, slidingly arranged in the inner sheath and connected with the covering body, the sheath core mechanism is used for with artificial valve detachably connected.In the release process of artificial valve, blood can flow out from the covering body through the flow-through hole.By artificial valve is housed in covering body, when input to implantation site, there is a certain gap between covering body and annulus, on the one hand, blood can flow through the gap between covering body and annulus, on the other hand, blood enters artificial valve and flows out from the flow-through hole on covering body.Avoid the displacement of covering body and artificial valve under the action of larger blood pressure, improve the position accuracy after artificial valve implantation.

A prosthetic heart valve (620) comprising: a frame (630); and a plurality of prosthetic leaflets (32) coupled to the frame (630) to allow blood flow in one direction. An antenna (28) is mechanically coupled to the frame (630) proximal to the plurality of prosthetic valve leaflets and includes one or more prosthetic valve coils (36). A first proximal peak (204A) and a second proximal peak (204B) defined by circumferentially adjacent first and second nearest stent cells (206A, 206B) of interconnected stent cells (192) of the frame (630), respectively, are located at a first peak angular position (208A) and a second peak angular position (208B) about a central longitudinal axis (60) of the frame (630), respectively. The antenna (28) is mechanically coupled to the frame (630) such that a center of mass (212) of the antenna (28) is located at an antenna angular position (214) between the first peak angular position (208A) and the second peak angular position (208B), and a closest point (216) of the antenna (28) is disposed axially between a 5mm proximal side and a 5mm distal side of the first proximal peak (204A) and the second proximal peak (204B). Other embodiments are also described.

The invention discloses an artificial heart valve which comprises a support and an artificial valve leaflet. The artificial valve leaflet is mounted in the bracket; the support is provided with an inflow section, a middle section and a fixed connection part section which are sequentially arranged in the axial direction of the support. And the inflow section and the fixed connection part section are in an external expansion state relative to the middle section. By means of the configuration, blood flow can conveniently enter the valve area through external expansion of the inflow section, meanwhile, the caliber of the artificial valve leaflet when the artificial valve leaflet is opened is enlarged through external expansion of the fixed connection part section, and therefore the occurrence rate of nebula in the blood vessel is reduced.

The invention discloses an artificial valve leaflet material, a valve leaflet, a valve and a preparation method.The artificial valve leaflet material is made of polyurethane and comprises an inner layer and surface layers located on the two opposite sides of the inner layer in the thickness direction, and the elastic modulus of the polyurethane on the surface layers is larger than that of the polyurethane on the inner layer. The valve leaflet material gives consideration to fluid mechanical property, biological stability, biocompatibility, creep resistance and fatigue resistance at the same time, and the performance required by a heart valve is achieved.

To support an operation so that an artificial valve can be indwelled at an appropriate angle for each patient.SOLUTION: A medical image processing apparatus includes an acquisition unit, a first region identification unit, a first direction identification unit, a second region identification unit, a second direction identification unit, and a feature amount calculation unit. The processing circuitry is configured to acquire a three dimensional medical image of a patient in whom an artificial valve needs to be placed. The first region specification unit specifies a first region of interest from the three dimensional medical image. The first direction identification unit identifies a first direction of the three dimensional medical image based on the first region of interest. The second region identification unit identifies a second region of interest from the three dimensional medical image. The second direction identification unit identifies a second direction of the three dimensional medical image based on the second region of interest. The feature amount calculation unit calculates a first feature amount related to the indwelling based on the first direction and the second direction.SELECTED DRAWING: Figure 1

To provide a side-deliverable transcatheter prosthetic valve including one or more anchoring elements for anchoring the prosthetic valve within an annulus of a native valve.SOLUTION: A side-deliverable transcatheter prosthetic valve includes an outer frame, a flow control component mounted within the outer frame, and an anchoring element coupled to a distal side of the outer frame. The prosthetic valve is foldable along a longitudinal axis and compressible along a central axis to a compressed configuration for side delivery via a delivery catheter and is expandable to an expanded configuration when released from the delivery catheter. An end portion of the anchoring element is configured to engage a guide wire. The anchoring element is extended during deployment to allow the anchoring element to capture at least one of native leaflet or chordae and, in response to the guide wire being disengaged from the end portion, transitions to a folded configuration to secure at least one of the native leaflet or the chordae between the anchoring element and the distal side of the outer frame.SELECTED DRAWING: Figure 25E