39 results about "Cardiac valve annulus" patented technology

The invention provides a left heart data analysis method and system based on image segmentation, and relates to the technical field of medical image processing. Comprising the following steps: acquiring cardiac ultrasound image data and preprocessing; performing image segmentation on the preprocessed image data to obtain a segmentation result including a left ventricle, a left ventricular wall and a left atrium; searching a boundary line of the left ventricle and the left atrium, selecting two boundary points corresponding to the minimum and maximum abscissas in the boundary line as left and right mitral valve ring points respectively, and establishing a long axis based on the mitral valve ring midpoint and the cardiac apex point; modeling the ventricle into a structure formed by superposing a plurality of discs along the long axis direction, and obtaining the diameter of the corresponding disc; based on the obtained diameters of the corresponding discs, the left ventricular volumes in the diastolic period and the systolic period are calculated respectively, and the left ventricular ejection fraction is calculated. According to the method, image segmentation and geometric modeling are fused to achieve accurate calculation of the cardiac ejection fraction, meanwhile, the accuracy of cardiac structure image segmentation is improved, and an interpretable ejection fraction estimation process is achieved.

A delivery system, method, and related device for facilitating the delivery and deployment of a cardiac implant. Such delivery systems and methods include the use of a pair of magnetic catheters, including an anchor delivery catheter carrying an anchor, which can be stacked with or axially offset from the magnetic head. Such systems further include the use of a puncture guidewire advanceable through the magnetic head of the anchor delivery catheter to establish access to the heart cavity, the puncture guidewire attached to a bridge element such that continued advancement of the guidewire draws the bridge element attached to the first anchor across the heart cavity while the bridge element remains covered by the magnetically coupled catheter. The methods and devices herein also enable cutting and removal of the bridge element of a deployed cardiac implant.

A mitral valve prosthesis to be implanted in a heart, comprises an asymmetrical ring, the asymmetrical ring is dimensioned to mimic a native mitral annulus of a patient; an anterior flexible leaflet and a posterior flexible leaflet, said leaflets suspended from the asymmetrical ring and configured to substantially coapt with each other; and at least four sets of cords, each set of cords attached to the anterior or posterior leaflet on a first end and attached into a cap on a second end, the cap is configured to be attached onto papillary muscles of the heart on another end of the cap.

A prosthetic heart valve with a collapsible and expandable outer frame which engages tissue of a native heart valve annulus. The outer frame has a narrowed waist portion between atrial and ventricular

To provide stents and prosthetic valves that can have a high degree of flexibility, without compromising mechanical integrity or functionality.SOLUTION: Prosthetic devices and frames to be implanted in a cardiac valve annulus include an annular frame (having an inflow end and an outflow end), and a plurality of axial frame members as bridges between two circumferentially extending rows of angled struts. The axial frame members can include a plurality of axially extending leaflet attachment members and a plurality of axial struts in a 1:1 ratio. Along each of the two rows, the frame can have at least three angled struts between adjacent axial frame members.SELECTED DRAWING: Figure 1

A heart valve prosthesis can be delivered within a native heart valve annulus using a delivery system that encases the heart valve prosthesis and sequentially permits expansion of a valve clasper and a lattice frame of the valve prosthesis. A sheath of the delivery system can be proximally retracted to permit the sinus locator to expand. Thereafter, a tubular member can be actuated to permit expansion of the lattice frame. Further, a clasper pusher of the delivery system, coupled to the tubular member, can be used to release a proximal portion of the sinus locator after release of the lattice frame. The delivery system can enable sinus locator engagement within the native annulus, sandwiching native valve leaflets between the expanded lattice frame and sinus locator, and thereafter permit disengagement of the sinus locator from the clasper pusher after the lattice frame expands.

Systems and methods of atrioventricular valve replacement are provided. In various embodiments, an arch-like support structure is provided that is insertable and implantable into a heart and is positioned in the mitral annulus to replace a native mitral valve. The support structure is operable to support, and various systems comprise leaflet and chord structures operable to control and regular blood flow between chambers of the heart.

The present application relates to the technical field of medical devices, and provides a valve prosthesis, comprising a stent and a bag body arranged on the stent. The stent comprises an extension body that can be located on one side of a cardiac valve annulus, and the side of the extension body opposite to the cardiac valve annulus is an outer side. The bag body is located on the outer side of the extension body. The bag body is provided with an opening that allows blood to enter. By means of the technical solutions of the present application, the valve prosthesis can better fit the cardiac valve annulus, thereby solving the problem of perivalvular leakage.

Systems, methods and associated devices for locking a tensioning element, such as a bridging element, suture, wire or string, during a medical procedure, such as placement of a medical implant in a subject are provided herein. The systems, methods and devices described herein are particularly useful for delivery and deployment of heart implants for reshaping a heart valve annulus for treatment of a heart disorder, such as mitral valve regurgitation.

In various embodiments, provided herein are methods, devices and systems to optimize delivery of ring-shaped articles for receiving transcatheter valves or stents. These methods, devices and systems are used to treat patients with valvular diseases. In some embodiments, the device includes at least three cables configured to hold a ring-shaped article having a center hole. The at least three cables are further configured to be anchored to supra-annular tissue at a heart valve peri-annular region. The ring-shaped article is positioned and deployed by means of at least three cables used to embed screws or anchors attached to the ring-shaped article into the supra-annular tissue; this deployed ring-shaped article is configured to receive a replacement heart valve in its inner lumen, thereby acting as a landing zone.

Mitral valve prolapse and mitral regurgitation can be treating by implanting in the mitral annulus a transvalvular intraannular band. The band is positioned so that it extends transversely across a coaptive edge formed by the closure of the mitral valve leaflets, to inhibit prolapse into the left atrium. At least one marginal chordae is severed, to permit leaflet closure against the band.

The present invention provides an artificial valve stent (100), an artificial valve structure, and a release method, which belong to the medical technology field. The artificial valve stent (100) includes a first stent (10) and a second stent (20), the first stent (10) including a first stent body (11) and a first positioning portion (12) for positioning on the first side (21) of the cardiac valve annulus, the first stent body (11) having a defined flow path (30) for blood flow, and the first positioning portion (12) extending radially outward from the first stent body (11), the second stent (20) includes a connecting portion (21) located radially outside the first stent body (11) and connecting to the first stent body (11), and a second positioning portion (22) for positioning on the second side (202) of the cardiac valve annulus. Such mitral valve stents can reduce the difficulty of releasing the artificial valve structure and improve the ease of the release procedure.

Annuloplasty rings that are size-adjustable after implant and which facilitate deployment and reduce long-term complications. The rings each have a hollow support body with a cinching element extending therethrough whose length is controlled remotely via a deployment system handle. The ring may be anchored to the annulus and then the size adjusted while the heart beats and under visualization to minimize regurgitation. The cinching element may be a loop of braided metal cable which cooperates with a junction housing to which the deployment system attaches. The rings are especially beneficial for repairing the mitral annulus, and may be saddle shaped with the junction housing located on an anterior side. The support body may be shape set nitinol tube having cutouts for flexibility, and the cinching element may be a braided nitinol core having a braided polymer exterior. The cinching element may be a complete loop, have one end anchored in the junction housing, or have two free ends extending out of the junction housing.

A valve prosthesis to be deployed within a native heart valve at a native heart valve annulus. The valve prosthesis including an expandable frame and a plurality of spaced anchors. The expandable frame includes a proximal end and a distal end and a longitudinal axis extending therethrough. The expandable frame collapses radially for delivery and expands radially upon deployment to an expanded configuration. The plurality of spaced anchors extend from the distal end of the frame towards the proximal end, each anchor formed with a free end, and each anchor being expandable from a collapsed anchor configuration to an expanded anchor configuration, wherein each of the anchors includes a foot angle of from 0 to 45 degrees relative to the longitudinal axis.

The present invention relates to mitral valve repair and replacement devices and methods. An implant and method for repairing and / or replacing the function of a native mitral valve, in various embodiments, is configured to reduce or eliminate mitral regurgitation and residual mitral valve leakage. A coiled anchor with a central turn that reduces in size after implantation is used to approximate the native mitral annulus size and reshape the native mitral annulus to reduce valve leakage. A clip can be further applied to the native valve leaflets to reduce the size of the native mitral annulus and reduce leakage therethrough. An artificial heart valve can be implanted in the coiled anchor to replace and further improve the function of the valve. In some cases, an artificial valve can be implanted in the clipped valve, with the clip detached from one of the native valve leaflets to provide space for the artificial valve to expand.

Mitral valve prolapse and mitral regurgitation can be treating by implanting in the mitral annulus a transvalvular implant. The transvalvular implant has a first end, a first anchoring portion located proximate the first end, a second end, a second anchoring portion located proximate the second end, and a central portion. The transvalvular implant can include a wire form curved body The transvalvular implant can include eyelets and the center of the transvalvular implant can include an opening. The central portion can be positioned so that it extends transversely across a coaptive edge formed by the closure of the mitral valve leaflets. Tricuspid regurgitation can be treated by implanting in the tricuspid annulus a transvalvular bridge. The transvalvular bridge can have a first anchoring portion and a second anchoring portion. The transvalvular bridge can positioned so that the bridge extends transversely across a coaptive edges formed by the closure of the leaflets. The transvalvular bridge can be positioned between a midpoint of the anterior annulus and straddling the commissure between the posterior annulus and the septal annulus. The transvalvular bridge can be anchored to the anterior annulus, the posterior annulus, and the septal annulus.

A template for a valve construct for replacement of at least one of a mitral valve and a tricuspid valve includes at least an anterior leaflet portion and at least a posterior leaflet portion, each leaflet portion having a proximal edge, a distal edge, and side edges extending between the proximal edge and the distal edge. The template further includes a plurality of substantially straight elongated chordae portions each having a proximal end connected to the distal edge of one of the at least two leaflet portions and a distal end extending therefrom and one or more papillary muscle head portions formed at a commissure between distal ends of at least two of the plurality of chordae portions. A total width of the leaflet portions of the template is substantially equal to a circumference of a native annulus of a heart valve.

Mitral valve prolapse and mitral regurgitation can be treating by implanting in the mitral annulus a transvalvular intraannular band. The band has a first end, a first anchoring portion located proximate the first end, a second end, a second anchoring portion located proximate the second end, and a central portion. The central portion is positioned so that it extends transversely across a coaptive edge formed by the closure of the mitral valve leaflets. The band may be implanted via translumenal access or via thoracotomy.

Mitral valve prolapse and mitral regurgitation can be treating by implanting in the mitral annulus a transvalvular intraannular band. The band has a first end, a first anchoring portion located proximate the first end, a second end, a second anchoring portion located proximate the second end, and a central portion. The central portion is positioned so that it extends transversely across a coaptive edge formed by the closure of the mitral valve leaflets. The band may be implanted via translumenal access or via thoracotomy.

An implantable artificial posterior mitral valve is described, wherein one variant typically includes a frame. A posterior leaflet having one or more scallops may be connected to the frame such that when the frame is deployed, the scallops extend from the frame for docking a native anterior leaflet. At least one arm member may be connected to the frame such that the arm member extends laterally in a curved configuration that is configured to approximate a bend of a native mitral annulus when the frame is deployed, and an anchoring leg may be connected to the frame and extend in an upward direction from a posterior side of the frame such that the anchoring leg extends laterally in a curved configuration that is configured to approximate a bend of the native mitral annulus when the frame is deployed. And a capture zone is defined between the anchoring leg and the rear side. The capture zone may be sized to receive at least a portion of the day then leaflet in an elongated state when the frame is deployed.

A method for performing a mitral or tricuspid annuloplasty and forming a support system within the heart is disclosed. The method includes puncturing, using a guidewire from a catheter, a center of a posterior sulcus from the left ventricle to the left atrium to create a central support point. The guidewire is then captured in the left atrium using an attachment device of a second catheter. Additional punctures are performed on each side of the central support point, followed by the attachment of anchor devices with ropes at each of the puncture sites. The ropes are deployed and interconnecting bars are released and attached to the ropes. The bars are then coupled using a zipper mechanism to constrict the annulus. The anchor devices, ropes, and interconnecting bars together form a support system that defines a stable axis spanning the mitral annulus and the interatrial septum.

The application discloses a method and device for evaluating the risk of stroke related to atrial fibrillation and a storage medium, relates to the technical field of risk evaluation, and comprises the following steps: acquiring a cardiac image of a patient; acquiring a left atrial model according to the cardiac image, wherein the left atrial model comprises a left atrial body, a mitral annulus, a pulmonary vein atrium and a left atrial appendage; calculating blood flow parameters of the left atrium according to the left atrial model, wherein the blood flow parameters comprise at least one of particle residence time and blood shear rate; and evaluating a first risk index of stroke of the patient according to the blood flow parameters. The application solves the problem of weak prediction ability of risk evaluation in the prior art, achieves the effect of individualized prediction of the risk of stroke according to the cardiac image of the patient, and improves the prediction accuracy.

An implantable prosthetic posterior mitral valve is described where one variation generally includes a frame. A posterior leaflet having one or more scallops may be connected to the frame such that the scallops extend from the frame for coaptation against a native anterior leaflet when the frame is deployed. At least one arm member may be connected to the frame such that the arm member extends laterally in a curved configuration configured to approximate a curvature of a native mitral annulus when the frame is deployed, and an anchoring leg may be connected to the frame and extend in a superior direction from a posterior side of the frame and defines a capture region between the anchoring leg and the posterior side. The capture region may be sized to receive at least a portion of a native posterior leaflet in an elongated state when the frame is deployed.

A replacement heart valve includes a self-expanding frame having an upstream end and a downstream end. A plurality of anchors extends from the downstream end of the frame. A valve skirt is attached to the frame and a valve body is attached to the valve skirt, wherein the valve body includes leaflets for providing one-way flow through the replacement valve. The frame preferably includes a plurality of connector eyelets sized to receive at least one tether. The replacement heart valve is radially collapsible for delivery within a delivery device and radially expandable for engaging a native heart valve annulus upon release from the delivery device. The tether may be used to control expansion and / or adjust the diameter of the replacement heart valve during deployment.

A system for use at an annulus of a valve of a heart of a subject comprises an implant and an implant-positioning device. The implant comprises (i) a wire; (ii) multiple anchors, slidably mounted in series along the wire, each of the anchors having: a slot through which the wire is threaded, and a pointy front end; and (iii) multiple tubes, the wire being threaded through each of the tubes such that the multiple tubes are slidably mounted on the wire alternatingly with the multiple anchors. The implant-positioning device is configured to implant the implant in the heart with the wire positioned along the annulus by, for each of the anchors: (i) positioning the anchor at the annulus, and (ii) using a deployment mechanism of the implant-positioning device, driving the pointy front end of the anchor into the annulus. Other embodiments are also described.

A heart valve prosthesis frame, the frame comprising a hollow tube shape for allowing blood to flow through; an upstream portion designed to expand to have at least one dimension wider than a native heart valve annulus; a downstream portion attached to the upstream portion, the downstream portion also designed to expand to have at least a portion with at least one dimension wider than the native heart valve annulus; wherein the downstream portion is shaped to have one side of the downstream portion of the hollow tube frame extend less from a center of the hollow tube than an opposite side of the hollow tube.

The heart valve annulus stabilizing, restraining, and reshaping device introduces a novel approach to cardiovascular interventions. Unlike conventional single restraining devices, it incorporates two separate elastic elements, each with half of a D-shaped configuration, significantly enhancing stability and flexibility. The system offers minimally invasive options, featuring multiple configurations for percutaneously delivering and strategically positioning on the respective valve annulus. Central to its effectiveness is a meticulously engineered fixation mechanism, featuring anchoring portions distributed strategically for optimal stability. The incorporation of a shape memory element empowers dynamic configuration adaptation, ensuring optimal engagement with the valve annulus, this allows for precise control over its dimensions. This versatile device promises enhanced patient outcomes through targeted annular modifications, offering a new level of precision in valvular interventions.

The implantable medical device is adapted to be implanted at an implantation site, such as a native heart valve annulus. The implantable medical device includes an expandable frame adapted to expand from a collapsed configuration for delivery to an expanded configuration for deployment, one or more valve leaflets fixed relative to the expandable frame, an inner skirt surrounding a portion of the expandable frame, and an outer skirt surrounding a portion of the expandable frame, the outer skirt attached to the expandable frame via one or more sutures that axially fix the outer skirt to the expandable frame but allow the outer skirt to move radially relative to the expandable frame. The outer skirt may move radially outward in response to fluid pressure, thereby improving the fluid seal against the native heart valve annulus.