21 results about "Mitral Valve Annulus" patented technology

The invention relates to the technical field of medical image analysis, in particular to a left ventricular compliance assessment method and system based on medical image.The method comprises the following steps that a planar three-dimensional coordinate from a left ventricular apex to a mitral annulus is obtained through a CT image, a thin-plate spline interpolation algorithm is called to establish a left ventricular long-axis model, the ultrasonic end-stage internal diameter is obtained synchronously, and a left ventricular compliance assessment result is obtained. And inputting the left greenhouse long axis model and the ultrasonic diastole end-stage inner diameter into an Euclidean distance calculation function to generate a left greenhouse length-diameter ratio. According to the method, a left greenhouse long axis model is constructed by integrating CT three-dimensional coordinates and ultrasonic inner diameter, the length-diameter ratio is calculated by combining Euclidean distance, point cloud registration is carried out, a myocardial wall area is segmented, local deformation is quantized by utilizing Gaussian curvature gradient, a correction factor is generated by inputting a radial basis function network, and a parameter coupling mechanism is established by fusing an aorta root angle. And optimizing the weight of the pressure-volume equation, establishing a dynamic model, and realizing a quantitative evaluation system of spatial heterogeneity and time continuity.

The invention provides a mitral valve replacement system in the technical field of medical instruments, and the mitral valve replacement system comprises a valve stent, a fixing ring and a shearing part, the fixing ring is arranged around the end face of the valve stent, and the shearing part is oppositely arranged on one side of the valve stent. The fixing ring surrounds the groove in the end face of the valve support to limit the moving direction of the valve support, so that the valve support is stably located at the native mitral valve ring, and the butterfly buckle is arranged on the valve support to buckle and clamp the native mitral valve leaflet. The fixing ring is tied and hooped at the groove in the end face of the valve support of the artificial heart valve, so that the artificial heart valve is stably positioned at the original mitral valve annulus, displacement of the artificial heart valve caused by external force factors such as blood flow impact force is prevented, and then the perivalvular leakage problem caused by displacement is avoided; the native mitral valve anterior leaflet is cut open through the cutting part, and then the cut native mitral valve anterior leaflet is buckled and clamped through the butterfly buckle, so that blood flowing through the native mitral valve anterior leaflet smoothly circulates, and the problem that the left ventricular outflow tract is obstructed is solved.

The invention relates to a self-expendable stent for placement at a mitral annulus that is self-expandable from an undeployed state to a deployed state comprising a stent frame having at least a first section and a second section arranged at a longitudinal axis of the stent, wherein the stent frame is formed by a plurality of endless arms, the arms being connected to one another at connection points forming a web-like structure with diamond-shaped cells; a dry valve made out of bovine pericardium arranged at least at the second section of the stent with the dry bovine pericardium being configured to be rehydrated with a solution, a skirt surrounding the dry valve and comprising at least one of bovine pericardium and polyester, and wherein, in the expanded state, a maximum outer diameter of the first section is larger than a maximum outer diameter of the second section, and wherein at least at a transition between the first section and the second section some of the endless arms extend outwardly beyond the web-like structure to form a hook, which faces the first section.

A mitral valve prosthesis to be implanted in a heart, comprises an asymmetrical ring, the asymmetrical ring is dimensioned to mimic a native mitral annulus of a patient; an anterior flexible leaflet and a posterior flexible leaflet, said leaflets suspended from the asymmetrical ring and configured to substantially coapt with each other; and at least four sets of cords, each set of cords attached to the anterior or posterior leaflet on a first end and attached into a cap on a second end, the cap is configured to be attached onto papillary muscles of the heart on another end of the cap.

A replacement mitral valve prosthesis includes a support structure and a valve body having three flexible leaflets. The support structure preferably includes an internal valve frame and an external sealing frame. The valve frame supports the flexible leaflets. The sealing frame is adapted to conform to the shape of the native mitral valve annulus. The sealing frame may be coupled to an inlet end of the valve frame, an outlet end of the valve frame, or both. A plurality of anchors is coupled to the outlet end of the valve frame. The anchors extend radially outwardly for placement behind native leaflets. The prosthesis preferably includes a skirt disposed along an exterior of the external sealing frame. The prosthesis is collapsible for delivery into the heart via a delivery catheter. The prosthesis is configured to self-expand for deployment in the heart when released from the delivery catheter.

The present invention discloses a mitral valve annulus contraction device, comprising a shaping ring body, a metal tube having a shape memory function, an automatic contraction section on the metal tube, the automatic contraction section comprising an inner connecting strip and an outer connecting strip located on the inner and outer sides of the shaping ring body; a fixing pin is connected between the inner connecting strip and the outer connecting strip, a stop pin is passed through the fixing pin, and a stop pin pull wire is passed through the stop pin. By providing a metal tube having a shape memory function, the mitral valve annulus contraction device is an annular structure similar to a heart valve before use, and the inner connecting strip and the outer connecting strip are fixed by the fixing pin to form a shape convenient for implantation. When the mitral valve annulus contraction device reaches the implantation position, the stop pin and the fixing pin are pulled out, so that the automatic contraction section on the metal tube automatically returns to an annular structure similar to a heart valve in its initial state under the shape memory function of the metal tube. The structure is simpler, the production cost is low, and the operation process is convenient.

Provided are devices and methods for augmenting mitral valve function. A cardiac valve prosthesis device comprises a stent frame assembly having an atrial portion and a ventricular portion, a peripheral ring attached to the stent frame assembly, which divides the stent frame assembly into the atrial and ventricular portions, and a plurality of valve leaflets fixedly coupled to the stent frame assembly. The peripheral ring fits over a native mitral valve annulus when the prosthesis device is implanted in a native mitral valve. The peripheral ring limits the protrusion of the stent frame assembly into a ventricular chamber and reduces the effect on ventricular outflow or excursion of a native leaflet by such protrusion.

Mitral valve prolapse and mitral regurgitation can be treating by implanting in the mitral annulus a transvalvular implant. The transvalvular implant has a first end, a first anchoring portion located proximate the first end, a second end, a second anchoring portion located proximate the second end, and a central portion. The transvalvular implant can include a wire form curved body The transvalvular implant can include eyelets and the center of the transvalvular implant can include an opening. The central portion can be positioned so that it extends transversely across a coaptive edge formed by the closure of the mitral valve leaflets. Tricuspid regurgitation can be treated by implanting in the tricuspid annulus a transvalvular bridge. The transvalvular bridge can have a first anchoring portion and a second anchoring portion. The transvalvular bridge can positioned so that the bridge extends transversely across a coaptive edges formed by the closure of the leaflets. The transvalvular bridge can be positioned between a midpoint of the anterior annulus and straddling the commissure between the posterior annulus and the septal annulus. The transvalvular bridge can be anchored to the anterior annulus, the posterior annulus, and the septal annulus.

The present application provides a mitral valve annulation system, including an implantation device and a delivery device; the implantation device includes a distal anchor, a proximal anchor, a locking structure and a locking wire; the distal anchor is used to anchor in the great cardiac vein, the proximal anchor is used to anchor in the coronary sinus, the locking structure is fixed to the proximal end of the proximal anchor, the distal end of the locking wire is fixed to the proximal end of the distal anchor, and the locking wire passes through the proximal anchor and the locking structure; the delivery device includes a delivery handle and a protective sleeve; the proximal end of the locking wire is connected to the delivery handle, and the unlocking rope of the locking structure is connected to the delivery handle, and the unlocking rope is used to control the opening and closing of the locking structure; the protective sleeve is installed in the delivery handle, and the distal end of the protective sleeve at least partially extends out of the delivery handle and is mounted on at least part of the locking wire, a rope hole is provided on the protective sleeve, and the unlocking rope passes through the rope hole; an anti-rotation structure is provided between the protective sleeve and the locking structure to prevent the protective sleeve and the locking structure from rotating relative to each other, so that the unlocking rope will not be entangled and will not affect the unlocking effect of the unlocking rope on the locking structure.

The application discloses a mitral valve replacement prosthesis and an outer support thereof, and belongs to the field of heart valve replacement prostheses. The outer support comprises, from top to bottom, an atrial fixation section located in an atrium, a mitral valve annulus blocking section and a mitral valve replacement prosthesis inner support connecting section located in a ventricle. The upper edge of the atrial fixation section and the lower edge of the inner support connecting section are circular or quasi-circular. The cross section of the mitral valve annulus blocking section is a wavy D-shaped structure. The connecting rods in the inner support connecting section comprise at least one wavy connecting rod. At least two identical or two different mark points are arranged on the petal structure of the atrial fixation section. The wavy D-shaped structure and the wavy rectangular structure are arranged, so that the circumferential rotation and the up-and-down displacement are effectively prevented, and the service life of the prosthesis is improved. The elastic wavy connecting rod is arranged, so that the production and processing success rate is improved and the service life is prolonged. The mark points are increased, so that the prosthesis is more easily identified during surgery, and the surgery efficiency and success rate are improved.

Various systems, devices and methods associated with the placement of a dock or anchor for a prosthetic valve. The anchor can comprise a plurality of coils adapted to support a valve prosthesis, the plurality of coils including an upper coil, one or more middle coils, and a lower coil. The upper coil can have a larger diameter than the one or more middle coils and the lower coil, and the upper coil is configured to engage a wall of an atrium of the heart at a position superior to and spaced axially from the mitral valve annulus after the plurality of coils have been fully delivered from the coil guide catheter.

The method, device and application of left atrial partitioning can realize the geographic calibration of electrophysiological analysis, achieve 100% repeatability, and easily perform independent in-depth analysis of each subregion of the left atrium, realizing the regional and refined depiction of the atrial fibrillation matrix. The method includes: (1) importing high-density mapping point cloud data exported from mainstream electrophysiological systems, including electrical parameters such as X, Y, Z coordinates, voltage, and activation time; (2) identifying key feature structures in the point cloud data, including the boundaries of the left pulmonary vein ablation circle, the right pulmonary vein ablation circle, the mitral valve annulus region, and the left atrial appendage region, and using these as the basic anchor points for partitioning; (3) constructing three-dimensional spatial geometric rules to unambiguously assign each data point to one of the anatomical regions; (4) outputting a new point cloud dataset with clear regional labels and generating statistical reports for each partition, or visually displaying three-dimensional models of partitions with different color codes.

Mitral valve prolapse and mitral regurgitation can be treating by implanting in the mitral annulus a transvalvular intraannular band. The band has a first end, a first anchoring portion located proximate the first end, a second end, a second anchoring portion located proximate the second end, and a central portion. The central portion is positioned so that it extends transversely across a coaptive edge formed by the closure of the mitral valve leaflets. The band may be implanted via translumenal access or via thoracotomy.

An implantable artificial posterior mitral valve is described, wherein one variant typically includes a frame. A posterior leaflet having one or more scallops may be connected to the frame such that when the frame is deployed, the scallops extend from the frame for docking a native anterior leaflet. At least one arm member may be connected to the frame such that the arm member extends laterally in a curved configuration that is configured to approximate a bend of a native mitral annulus when the frame is deployed, and an anchoring leg may be connected to the frame and extend in an upward direction from a posterior side of the frame such that the anchoring leg extends laterally in a curved configuration that is configured to approximate a bend of the native mitral annulus when the frame is deployed. And a capture zone is defined between the anchoring leg and the rear side. The capture zone may be sized to receive at least a portion of the day then leaflet in an elongated state when the frame is deployed.

The invention provides a mitral valve forming ring. The mitral valve forming ring comprises an inner core, and the inner core is configured to be capable of being plastically deformed from a first form to a second form under the expansion action of external force and kept in the second form. Wherein the first form is a saddle-shaped non-circular closed form conforming to a native mitral valve annulus, and the second form is a closed form which is flatter and closer to a circle than the first form. The mitral valve forming ring creates conditions for follow-up valve-in-ring operation, plastically deforms from a first form and is kept in a flatter and approximately circular second form in a transcatheter balloon dilatation mode, and the mitral valve forming ring can be matched with a cylindrical valve frame of an artificial valve prosthesis. The mitral valve forming ring in the second form is used for stably positioning the artificial valve prosthesis, and the occurrence probability of perivalvular leakage is remarkably reduced.

This invention provides a mitral valve annulus retraction device and system, relating to the field of medical device technology. The mitral valve annulus retraction device includes multiple connecting tubes, which are sequentially connected through annulus retraction nodes to form a forming tube. Both ends of the forming tube are provided with annulus retraction nodes. Each annulus retraction node includes an annulus retraction locking component and a positioning puncture component. The positioning puncture component includes a locking block. The annulus retraction locking component includes a locking sleeve, the sidewall of which has at least one locking groove spaced circumferentially. The locking block is disposed within the locking sleeve and engaged within the locking groove, which restricts unidirectional movement of the locking block within the locking sleeve. This invention solves the problem in existing technologies where the annulus retraction ring cannot effectively counteract ventricular contraction forces for a long period, resulting in the inability to maintain the therapeutic effect for an extended period. It provides stable positioning and can maintain the therapeutic effect for a longer time.

The application provides a mitral annuloplasty system, which comprises a proximal anchor, a push rod, a protective sleeve and a delivery handle; the proximal anchor is used for anchoring in a human body, and the proximal end of the proximal anchor is provided with a proximal anchor connector; the push rod has flexibility at least in the part of the human body, the proximal end of the push rod is connected with the delivery handle, the distal end of the push rod is provided with a push rod connector, and the push rod connector and the proximal anchor connector can be buckled with each other; the protective sleeve has flexibility, the proximal end of the protective sleeve is connected with the delivery handle, the distal end of the protective sleeve can be sleeved on the connection part of the push rod connector and the proximal anchor connector, and the push rod connector and the proximal anchor connector are limited to prevent the push rod connector and the proximal anchor connector from loosening; and after the protective sleeve is removed, the push rod connector can be separated from the proximal anchor connector under the elastic action of the push rod, so that the flexibility of the push rod connector and the push rod is better, and the push rod can be bent and withdrawn from the human body smoothly.

The present application provides a mitral valve annulation system, including a delivery device and an implantation device; the implantation device includes a distal anchor, a proximal anchor, a locking structure and a locking wire; the distal anchor is used to anchor in the great cardiac vein, the proximal anchor is used to anchor in the coronary sinus, the locking structure is fixed to the proximal end of the proximal anchor, the distal end of the locking wire is fixed to the proximal end of the distal anchor, and the locking wire passes through the proximal anchor and the locking structure; the unlocking piece of the locking structure is connected to the delivery device, and the proximal end of the locking wire is connected to the delivery device, and the delivery device can implant the distal anchor, the proximal anchor, the locking structure and the locking wire into the human body; the delivery device can control the opening and closing of the locking structure through the unlocking piece; the delivery device can drive the distal anchor close to or away from the proximal anchor, so as to achieve the adjustment of the relative position of the distal anchor and the proximal anchor, and adjust the degree of annulation of the mitral valve by the proximal anchor and the distal anchor to achieve a better annulation effect; in addition, implanting the implantation device into the human body through the delivery device is beneficial to the functional repair of the mitral valve.

In some embodiments, a method includes delivering to a native valve annulus (e.g., a native mitral valve annulus) of a heart a prosthetic heart valve having a body expandable from a collapsed, delivery configuration to an expanded, deployed configuration. The method can further include, after the delivering, causing the prosthetic heart valve to move from the delivery configuration to the deployed configuration. With the prosthetic heart valve in its deployed configuration, an anchor can be delivered and secured to at least one of a fibrous trigone of the heart or an anterior native leaflet of the native valve. With the prosthetic heart valve disposed in the native valve annulus and in its deployed configuration, an anchoring tether can extending from the anchor can be secured to a wall of the heart to urge the anterior native leaflet towards the body of the prosthetic heart valve.

The invention relates to the technical field of medical instruments, and discloses a heart mitral valve replacement device which comprises a first covering film, and the surface of one end of the first covering film is connected with a left atrial side positioning piece. The left atrial side positioning piece is tightly attached to a mitral valve ring, the atrial side positioning piece and the lower edges of valve leaflets form clamping force through chordae tendineae, the displacement phenomenon of the valve in the heartbeat process is effectively avoided, the success rate of the valve replacement operation is greatly increased, the displacement risk is reduced, the three-leaf valve is opened and closed in the shape of three valve leaflets, and the valve replacement efficiency is improved. In the blood flowing process, the valve leaflets can be smoothly opened and closed, blood flow resistance is reduced, blood backflow is avoided, recovery and maintenance of heart functions are facilitated, and the valve can be conveniently stored in a conveying device in the implanting process due to the compressible deformation and shape memory functions of the nickel-titanium alloy net and the ventricular side positioning piece; and accurate release is realized after the target position is reached, so that the surgical operation is simpler and more convenient.

Exemplary methods of performing an annuloplasty procedure include introducing a catheter into the left atrium of the heart, deploying a first member from the catheter, anchoring the first member to the posterior side of the mitral valve annulus in the left atrium, deploying a second member from the catheter, anchoring the second member to the anterior side of the mitral valve annulus in the left atrium, deploying a flexible tension member from the catheter, attaching the tension member to both the first member and the second member, and applying tension to the tension member to pull the first member and the second member toward each other and bring the posterior and anterior sides of the mitral valve annulus closer together. Annuloplasty systems and components are also disclosed.