7 results about "Paravalvular leakage" patented technology

A transcatheter heart valve includes a paravalvular seal that is configured for transfemoral delivery. The valve includes a frame and the seal is formed from a plurality of outwardly extending fibers.

This invention discloses a novel valve stent and artificial heart valve, belonging to the field of medical device technology. The valve stent has a hollow, symmetrical, mesh-like tubular structure, with a first layer of hexagonal mesh groups, a second layer of polygonal mesh groups, and a third layer of polygonal mesh groups arranged sequentially from the outflow end to the inflow end. The stent has a small overall mesh count and symmetrical structure, resulting in uniform deformation during compression and expansion. It exhibits excellent radial support and minimal expansion rebound, significantly reducing the risk of paravalvular leakage. While maintaining radial support, this invention can reduce the stent strut width to 0.2–0.4 mm, and the minimum outer diameter of the valve after compression can reach 2.5–4.5 mm. Simultaneously, the overall length change during stent compression and expansion is minimal, greatly improving the smoothness of vascular delivery and the accuracy of valve implantation positioning. This meets the clinical needs of transcatheter aortic valve replacement surgery, enhancing the safety and effectiveness of artificial heart valve implantation.

This invention provides a transcatheter valve prosthesis comprising a stent, a prosthetic valve component, and a paravalvular leakage prevention component. The paravalvular leakage prevention component is coupled to the stent and includes an inner skirt, an outer covering, a lumen, an opening, and a one-way valve. The inner skirt is disposed on an inner surface of the stent and has an inflow end and a downstream end. The outer covering surrounds an outer surface of the stent and has an inflow end and a downstream end, the inflow end being coupled to the inflow end of the inner skirt. The lumen is formed between the outer surface of the inner skirt and the inner surface of the outer covering. The opening is disposed between the inner skirt and the outer covering. The one-way valve includes a flap at the opening, the flap being configured to open to allow blood to flow into the lumen but prevent blood from flowing out of the lumen.

This invention relates to a valve prosthesis, which includes a support body and an elastic element disposed outside the support body. The support body has a through-hole, and the elastic element is arranged circumferentially around the support body, forming an annular cavity structure with the support body. The through-hole communicates with the annular cavity structure. Thus, by providing a through-hole in the support body, the through-hole communicates with the semi-closed structure, allowing blood flow within the semi-closed structure to flow out through the through-hole, preventing blood from stagnating within the semi-closed structure and forming a thrombus, thus promoting smooth blood flow. Furthermore, blood flow in the opposite direction can flow into the elastic element, where it is buffered, preventing blood from directly overflowing from the sidewall of the stent due to the through-hole in the inner fabric, thus avoiding paravalvular leakage.

The application relates to a paravalvular leakage plugging device applied to a prosthetic valve with an annular body, comprising biodegradable foam attached to at least a section of the outer periphery of the annular body, which is water-swellable and has a first degradation rate; and a film wrapping the biodegradable foam, which is configured as a porous film and has a second degradation rate; when the biodegradable foam swells upon contact with water, the film does not constrain the swelling of the biodegradable foam, and the first degradation rate is different from the second degradation rate. The paravalvular leakage plugging device adopts biodegradable foam to plug the leakage, compared with a traditional metal plugging device, does not cause damage to the heart tissue and the valve, reduces the risk of complications, and meanwhile, the biodegradable foam gradually degrades after completing plugging, so that no residues are left in the human body, further reducing the long-term risk.

Provided in the present application is a double-orifice mitral valve replacement implant, which comprises a cloth-covered outer stent and an inner valve stent. The cloth-covered outer stent is sleeved around the periphery of the inner valve stent. The inner valve stent comprises a first inner stent and a second inner stent arranged side by side, and a first biological valve and a second biological valve are arranged in the first inner stent and the second inner stent, respectively. An accommodating gap is formed among the cloth-covered outer stent, the first inner stent, and the second inner stent. A flow blocking skirt is arranged in the accommodating gap, one side of the flow blocking skirt is connected to an inner wall of the cloth-covered outer stent, and the other side is attached to peripheries of the first inner stent and the second inner stent. A tightening thread is threaded through an edge of the flow blocking skirt close to the first inner stent or the second inner stent. The present application effectively solves the problems of paravalvular leakage and leakage through a fitting gap between an inner stent and an outer stent, thereby exhibiting high safety.

Embodiments herein include a cardiac stent-valve for transcatheter delivery being compressible to a compressed state for delivery, and expandable to an expanded state for implantation. The stent-valve including a stent with an axial inflow end and an axial outflow end, a plurality of leaflets arranged within the stent, and a sealing skirt for reduction or prevention of paravalvular leakage. In the expanded state, the sealing skirt includes a tubular inner wall and at least one pocket which is positioned on the tubular inner wall and comprises an outer wall which extends radially outward from the tubular inner wall. The pocket is configured to be distended radially outward in response to inflow of blood in the expanded state. In the expanded state, the outer wall of the pocket includes one or more pre-shaped bulges which extend radially outward from the outer wall of the pocket. Other embodiments are also included herein.