129 results about "Systole" patented technology

The invention provides an intelligent auxiliary evaluation system for right ventricular systole and diastole functions of echocardiography, and aims to solve the problems of low accuracy and efficiency in right ventricular function evaluation in the prior art. The system comprises an image acquisition unit, an image processing unit, a feature extraction unit, an intelligent evaluation unit and a result output unit, and through an intelligent algorithm, especially a deep learning network DL and a convolutional neural network CNN, a feature extraction result is obtained. Key indexes such as a two-dimensional right ventricular area change fraction 2D-FAC, a right ventricular ejection fraction RVEF and tricuspid valve ring plane contraction period displacement TAPSE are automatically calculated. The system also realizes accurate evaluation of the right ventricular function through a specific CNN structure and loss function design. The system can provide rapid, accurate and non-invasive right ventricular function evaluation in clinical practice, and is helpful for improving the diagnosis and treatment effects of cardiovascular diseases.

Coaptation assist device for repairing cardiac valves and associated systems and methods are disclosed herein. A coaptation assist device configured in accordance with embodiments of the present technology can include, for example, a fixation member configured to press against cardiac tissue proximate to a native valve annulus, and a stationary coaptation structure extending away from the fixation member. The coaptation structure can include an anterior surface configured to coapt with a first native leaflet during systole and a posterior surface configured to displace at least a portion of a second native leaflet. The device also includes at least one sensor configured to detect parameters associated with at least one of cardiac function and device functionality. The sensors can be pressure sensors configured to detect left atrial pressure and / or left ventricular pressure.

An aorta intervention catheter device for heart failure comprises a catheter and a bag body arranged at one end of the catheter, an elastic diaphragm is arranged in the bag body, an inner cavity of the bag body is divided into a blood chamber and an air chamber by the elastic diaphragm, the blood chamber is communicated with the catheter, an exhaust assembly is arranged on the bag body, and the air chamber is connected with an air source connector arranged on the bag body; the other end of the catheter is a proximal end, first guide films which are staggered at intervals and inclined towards one side of the proximal end and second guide films which are inclined towards a distal end are arranged on the inner wall of the catheter, and first guide holes and second guide holes which correspond to the first guide films and the second guide films and are communicated with an inner cavity of the catheter are respectively formed in the outer wall of the catheter; the proximal side of the second guide film is provided with at least one set of third guide films which are fixed to the inner wall of the catheter, incline towards the distal end and are tightly attached to each other to be closed. The aorta is directly intervened to enter the heart, and coronary artery blood perfusion is increased in the diastolic period; the left ventricular post-load is reduced in the systolic period, and the heart failure can be more directly treated.

The invention discloses a TAVR postoperative blood flow parameter complementing method based on CT-MRI fusion, and belongs to the technical field of crossing of medical image processing and computational fluid mechanics. A CT valve frame registration technology is adopted, an invisible artificial valve leaflet three-dimensional structure is reconstructed through valve frame information in a CT image and is coupled with a dynamic heart model, a complete valve mechanical and functional simulation platform is constructed, the problem of an imaging blind area is solved, hemodynamic parameters of an inlet and an outlet of a postoperative area are further collected in combination with 4D Flow MRI, and the artificial valve leaflet three-dimensional structure is obtained. The blood flow conditions of the upstream and the downstream of the artificial valve area at each stage of contraction and relaxation of the TAVR postoperative part are comprehensively restored, the temporal-spatial resolution and the physical authenticity of the boundary condition in fluid-solid coupling simulation are greatly improved, and the more real passive response of the valve leaflet under the action of the blood flow is obtained; and a reliable basis is provided for quantitative and mechanical risk analysis of postoperative complications such as thrombosis, perivalvular leakage and valve leaflet fatigue.

The invention relates to a heart health state detection method and device and electronic equipment, and the method comprises the steps: determining a plurality of first feature sets and a plurality of second feature sets in a short-time feature set based on a to-be-detected heart sound signal, each first feature set being determined based on the signal amplitude of the heart sound signal in a corresponding window at each sampling point, and each second feature set being determined based on the signal amplitude of the heart sound signal in the corresponding window at each sampling point; each second feature set is determined based on the duration of a first heart sound interval, a systolic period, a second heart sound interval and a diastolic period included in each cardiac cycle in the heart sound signal in the corresponding window; based on the heart sound signal to be detected, a time domain feature set, a frequency domain feature set and a Poincare map related parameter set in the long-time feature set are determined, the time domain feature set is determined based on the duration of each cardiac cycle, the frequency domain feature set is determined based on signal power, and the Poincare map related parameter set is determined based on a Poincare map generated based on the duration of each cardiac cycle; and inputting the short-time feature set and the long-time feature set into a set heart health state detection model to obtain a heart health state result.

The invention relates to the technical field of medical imaging, and provides an automatic measurement method, system and equipment for the cardiac muscle full segment thickness of an echocardiogram, and the method comprises the steps: determining a sector rectangular frame in an ultrasonic video stream through employing a deep learning target detection model, so as to determine a cutting region; cutting the ultrasonic video stream based on the cutting area, and scaling the cut ultrasonic cardiac image to a target size in an equal proportion; performing feature extraction on the echocardiography image through a feature extraction module and generating a feature map; cardiac muscle segmentation is completed through the cardiac muscle segmentation module, and mitral valve endpoint recognition is completed through the mitral valve endpoint recognition module; based on the data obtained by the myocardial segmentation module and the mitral valve endpoint identification module, a post-processing module is adopted to calculate and visually output a myocardial full segment thickness result at the end of diastole or end of systole; the cardiac muscle full segment thickness can be effectively measured, the accuracy and repeatability of cardiac function parameter measurement can be improved, and the medical examination process is optimized.

The invention relates to an apparatus for determining an indicator, which is representative for a physiological parameter of a patient like a fluid responsiveness parameter, based on a pulse signal. The apparatus determines a) a respiratory pulse variation signal (r0) corresponding to pulse variations caused by ventilation or respiration induced heart-lung interaction based on the pulse signal and b) a systolic part of the respiratory pulse variation signal, which corresponds to a time period in which an increasing or decreasing applied pressure passed the systolic arterial pressure of the patient and which therefore is prone to comprising an artifact. Moreover, the respiratory pulse variation signal is modified such that the determined systolic part of the respiratory pulse variation signal is corrected, wherein the indicator is determined based on the measured pulse signal and the modified respiratory pulse variation signal. This procedure allows for a more accurate determination of the indicator.

The utility model relates to the technical field of medical apparatus and instruments, in particular to a heart valve forming ring implantation assembly which comprises a forming ring body which comprises an annular main body arranged in a chain type structure. The ring holder comprises a ring holding part, the ring holding part comprises a shell and a ring holding sleeve piece movably arranged at the lower end of the shell, the ring holding sleeve piece comprises a limiting block, a movable connecting part arranged at the upper end of the limiting block and a plurality of supporting rods arranged on the periphery of the lower end of the limiting block, and ring holding pieces are arranged at the tail ends of the supporting rods. The shell is provided with an operation assembly; and when the movable connecting part moves downwards, the plurality of supporting rods drive the ring holding piece to extend outwards. The forming ring can be adapted to forming ring bodies with various sizes; expansion of the valve ring cannot be caused, and the influence of the annular body on the valve ring in the contraction period is eliminated; the operation is simple and fast; a doctor can observe and use the device conveniently, more operation visual fields are provided, and the device is more suitable for small incision operations.

The present invention discloses a closure device for mitral valve leaflet repair, which relates to the technical field of mitral valve leaflet repair. The present invention includes an upper jaw assembly, one side of the upper jaw assembly is set to an opening shape, and a positioning clamp assembly is slidably connected to the inner wall of the opening. The end of the positioning clamp assembly is provided with an outer protrusion, and the top of the upper surface of the outer protrusion is provided with a hook-shaped groove. The present invention utilizes the continuous abutment and approach of the closure assembly to finally connect the port with the clamp arm, thereby forming an integrated structure between the closure assembly and the two clamp arms, so that the closure assembly is connected to the bottom of the mitral valve, and the first clamp arm and the second clamp arm are connected to the top of the mitral valve. Therefore, during the systole of the heart, the mitral valve is tightly closed, preventing blood from the left ventricle from flowing back to the left atrium, thereby ensuring that blood can be pumped from the left ventricle into the aorta in the correct direction, and the closure assembly can be closed without relying on external force. Compared with the existing technology, the external operating structure for controlling the turning is saved.

This application relates to a fully automated method and apparatus for quantitative analysis of myocardial acoustic contrast imaging. The method includes: acquiring myocardial acoustic contrast imaging images; segmenting the acquired myocardial acoustic contrast imaging images to obtain myocardial segmentation images; calculating the cardiac chamber area based on the myocardial segmentation images; automatically extracting the myocardial segmentation results at the end of cardiac systole using the periodic changes in cardiac chamber area; using the extracted end-systolic segmentation results as a mask to extract the corresponding position of each image as a target region for registration, thereby generating a one-to-one correspondence of registered image sequences; fitting a function model based on the pixel values ​​of each point in the registered image sequence; and generating a parametric image based on the registered image sequence and the fitted function model. Therefore, this application can perform fully automated quantitative analysis of myocardial acoustic contrast imaging.

The invention discloses a self-adaptive control method and equipment based on an external counterpulsation device and a medium, and relates to the technical field of hemodynamics, and the method comprises the following steps: obtaining the gas inflation and deflation speed of the external counterpulsation device, carrying out air bag volume accumulation analysis on the gas inflation and deflation speed, and determining air bag volume data; based on the air bag volume data, through air bag pressure change analysis, blood vessel pressure data generated by the air bag on the limb is obtained; according to the blood vessel pressure data, the blood inflow amount of the left atrium is determined through blood backflow state analysis in the diastolic period; performing left ventricular ejection stroke-per-volume analysis on the left atrium blood inflow in a systolic period to obtain cardiac output data; based on cardiac output data or gas inflation and deflation speed, a self-adaptive regulation and control strategy of the in-vitro counterpulsation device is determined through real-time analysis of hemodynamic parameters. By means of the method, the problem that in the prior art, the external counterpulsation device cannot be adjusted in real time according to the current state of the user is solved.

An implantable circulatory support system, configured to connect a ventricular chamber of a heart, including a valveless displacement blood pump, a deformable polymeric flow cannula, a pair of male and female fasteners, a coupler, a driveline assembly, and a co-pulsatile driver. Forward and backward flow communication between the blood pump and the heart chamber is accomplished using the present flow cannula invention which is anastomosed to the heart chamber in a sutureless manner. When providing circulatory support, the co-pulsatile driver ejects blood out of the blood pump during systolic ventricular contraction and fills the blood pump with blood during diastolic ventricular relaxation.

Apparatus and methods for repairing a cardiac valve, e.g., a tricuspid valve, are provided. The apparatus may include a prosthetic device coupled to an elongated support coupled to a stent configured to be implanted within a vessel, e.g., the superior vena cava, to suspend and maintain the prosthetic device within the cardiac valve. The support may include a proximal, delivery portion detachably coupled, in a delivery state, to a distal, implantable portion coupled to the prosthetic device. The prosthetic device may be formed of biocompatible material coupled to a frame, and may have prosthetic leaflets that allows blood to flow therethrough in one direction during diastole, but prevents blood regurgitation during systole. The stent further may include features configured to resist migration of the stent within the vessel, as well as to prevent in-folding of the stent during deployment.

This invention discloses a non-contact electrocardiogram (ECG) measurement method using millimeter-wave radar. First, the original chest wall displacement signal acquired by the millimeter-wave radar is preprocessed to obtain a displacement feature branch input. Then, the original displacement signal undergoes cardiac sound band enhancement, wavelet denoising, and envelope extraction to obtain radar cardiac sound features. A hidden semi-Markov model is constructed to model the states of the first heart sound, systole, second heart sound, and diastole in the cardiac cycle, obtaining the posterior probability of the state at each time point. Next, the displacement features, radar cardiac sound features, and state probability features are input into a multi-branch convolutional fusion network, combined with a bidirectional long short-term memory network to achieve temporal correlation modeling, finally outputting the reconstructed human ECG result. This invention achieves non-contact ECG measurement without skin electrode contact by fusing the original mechanical displacement of the chest wall, the mechanical vibration features of the heart sounds, and the explicit state prior information of the cardiac cycle.

This invention provides an apparatus for repairing heart valves and a method for implanting anchors and repairing heart valves. The apparatus includes: a body; a component attached to the body at a first end and having a plurality of positioning cords extending laterally across a space between the component and away from a second end of the component opposite to the first end; a tube suspended from the plurality of positioning cords; and an adjustment cord extending through the tube. The method includes: implanting at least one annular anchor into the mitral valve annulus of a heart valve; implanting papillary anchors through each papillary muscle of the heart; delivering and positioning the apparatus for repairing the heart valve within the heart valve using at least one annular anchor and papillary anchors; and adjusting the apparatus to adjust the degree of atrial displacement of the mitral valve leaflets during ventricular systole.

A method for operating a blood pressure measuring apparatus includes the steps of: applying a measuring apparatus, containing a pressure unit and / or a pressure measuring unit, to a measurement point on the body; initialising the measuring apparatus by carrying out a reference measurement and / or by carrying out defined position changes to the measurement point and determining person-specific initialisation parameters; storing the person-specific initialisation parameters in a memory and control unit; carrying out at least one blood pressure measurement by applying a counter pressure to the pressure unit in a sub-systolic low-pressure range; maintaining the applied counter pressure within a plateau phase having a predefined duration and recording blood pressure time curve data during the predefined duration; converting the recorded blood pressure time curve data over the initialisation parameters into arterial blood pressure data over time.

The present application discloses a blood pump speed pulsation control method, system, and related products. The method: based on the electrical signal change information of the blood pump motor within a historical period, detects the start time of the N0 diastole and the start time of the N0 systole of the current patient's heart beat within the historical period; based on these start times, determines the start time of the N1 diastole and the start time of the N1 systole of the heart after the historical period. The method uses the patient's individual historical electrical signal change information as a basis to determine the future start time of the diastole and the start time of the systole of the current patient's heart, ensuring that the speed adjustment time of the blood pump motor is personalized to conform to the physiological contraction law of the individual heart, and realizing the specific output of the blood pump such as the blood pumping time and the blood pumping volume per time to flexibly follow the blood flow pulsation output of the heart beat, that is, to assist the blood pump in generating a pulsating flow synchronized with the natural heart beat, thereby effectively and reliably maintaining the patient's life safety.

A blood pressure monitoring device includes a wristband, a housing, and a display. The strap portion is adapted to secure the device to the wrist without obstructing blood flow. At least one sensor modality is disposed within the housing for obtaining sensor data from an artery in the wrist. In a preferred embodiment, a photoplethysmography sensor is incorporated in a housing to generate PPG waveform data. A processor within the housing is operable to calculate an average arterial pressure based on the extracted and calculated characteristics of the sensor data, and optionally to calculate diastolic and systolic blood pressures. Related methods and systems are also described.

In order to determine the presence or absence of pre-constriction with high accuracy on the basis of an image of a heart, a pre-constriction determination device (1) is provided with: an acquisition unit (101) that acquires a signal waveform indicating a time-series change in the area of each ventricle and each atrium region in the image of the heart; and a determination unit (104) that determines whether or not there is a pre-period contraction by comparing the time interval from the point in time when the area indicated by the signal waveform reaches the reference value to the point in time when the area reaches the reference value again with a predetermined threshold value.

Vascular blood flow modulation is disclosed using metallic compliance-enhancement devices that contain a sealed volume of fluid. The device includes a first elongated inflatable nitinol balloon and a second elongated inflatable nitinol balloon, each having an outer sealed terminus and an inner open fluid port, and a nitinol connector tube that fluidly couples the balloons and has a diameter smaller than the inflated diameters of the balloons. The first balloon is positioned within an arterial vessel and the second balloon is positioned within a venous vessel, with the connector tube spanning between the vessels. During systole, arterial pressure compresses the first balloon to drive fluid through the connector tube into the second balloon, thereby expanding the second balloon and increasing venous blood flow. Cyclic systolic and diastolic pressure variations cause fluid to shuttle between the balloons, producing a compliance-enhancing effect.

The present application relates to the field of assist devices and provides a left ventricular flexible assist device, wherein a catheter support of the device is arranged in a reflux catheter; a first opening is arranged at the top of the catheter support, a second opening is arranged at the bottom of the catheter support, and the side of the catheter support is a hollow structure; a trileaflet valve is fixedly connected to the inner side of the catheter support; a third opening is arranged at the top of the suction catheter, a fourth opening is arranged at the bottom of the reflux catheter, a fifth opening is arranged at the top of the reflux catheter, the third opening passes through the fourth opening and the second opening, and is fixedly connected to the bottom of the trileaflet valve; the support valve is arranged between the catheter support and the suction catheter; a blood discharge hole is arranged on the side of the reflux catheter, and a suction hole is arranged on the side of the suction catheter. The device provided by the present application can aspirate blood from the left ventricle during systole while avoiding the accidental aspiration of blood from the ascending aorta out of the body, and discharge blood into the ascending aorta during diastole while avoiding the accidental discharge of blood into the left ventricle.

The embodiment of the invention provides an in-aorta pressure reduction pump which comprises a diaphragm assembly capable of enabling liquid to flow in one direction and a pressure reduction pump, the pressure reduction pump is connected with the diaphragm assembly, and the flow directions of the pressure reduction pump and the diaphragm assembly are the same; the diaphragm assembly comprises a diaphragm body used for clamping the inner side of the aorta. In the direction of the axis of the diaphragm body, the outline of the pressure reduction pump is smaller than the size of the diaphragm body; the input end and the output end of the pressure reduction pump are located on the two sides of the plate face of the diaphragm body respectively. According to the technical scheme, the aorta is clamped through the diaphragm assembly, a buffer area can be formed outside the aortic valve, the buffer area can normally circulate during aorta ejection and is closed in the diastolic period, then a low-pressure area is formed in the buffer area in the diastolic period in a decompression pump extraction mode, the resistance of left ventricle ejection in the systolic period is reduced, and the cardiac effect is improved. And blood is prevented from flowing back through the incompletely closed aortic valve, so that the heart load is reduced, and the treatment effect is achieved.

A prosthetic heart valve, for example a tricuspid valve, may include a flexible membrane and a frame. The frame may be attached to the periphery of the tricuspid orifice. The diaphragm may be attached to the frame around a part of the perimeter of the orifice. Optionally the frame may be flexible. For example the frame may elastically flex between a substantially circular shape and / of an elliptical and / or crescent shape. Optionally there may not be a stiff cross piece crossing a central region of the orifice and connected on opposing sides of frame. In some embodiments, the diaphragm may take a dome shape during systole.

One aspect of the invention relates to a mechanical circulatory assistance device (100) comprising: - a stem (11) that is intended to be inserted into a blood vessel; - a plurality of fins (12) attached to the stem (11), the plurality of fins comprising an electroactive material; - a control module (14) connected to the plurality of fins (12), wherein the control module (14) is configured to: o obtain information relating to a systole of a cardiac cycle; and o on obtaining the information, control actuation of the plurality of fins (12) so as to cause the plurality of fins (12) to move, the movement being a folding of the plurality of fins (12) towards the stem (11) in a direction corresponding to a direction of blood flow through the blood vessel. Drawing_references_to_be_translated

The application discloses a noninvasive calculation method of coronary microcirculation resistance and resistance index, and the method comprises the following steps: firstly, based on coronary computer tomography angiography data, blood vessel segmentation is carried out by using a U-Net convolutional neural network, and then a personalized 3D coronary stenosis branch vessel model is reconstructed; secondly, the information of multiple blood vessels (physiological parameters such as age, blood pressure and left ventricular volume in the systolic phase) is integrated, and the length, cross-sectional area, volume and other geometric structure parameters of a specific part of the blood vessel are measured and calculated; thirdly, fluid dynamics simulation is utilized to obtain the invasive CMR and IMR; fourthly, correlation analysis is carried out between the characteristic parameters and the CMR and IMR; fifthly, the characteristic parameters with high correlation are selected to carry out machine learning prediction, so as to realize noninvasive calculation of the CMR and IMR. The noninvasive method for evaluating the CMR and IMR can complete measurement in a short time and has high precision, and is convenient and safe.

The present application discloses a blood pump flow adaptive control method, system and related products. The embodiments of the present application use the patient's individual historical electrical signal change information as a basis to determine the start time of the diastole and the start time of the systole of the current patient's heart in the future, which can ensure that the speed adjustment time of the blood pump motor is personalized and conforms to the physiological contraction law of the individual heart; wherein, the start time of the current beating period is determined according to the duration of one single historical beating period, and the start time of the next beating period is detected within the latest corresponding duration of the current beating period, which can achieve the specific outputs of the blood pump such as the blood pumping time and the blood pumping volume each time to flexibly follow the blood flow pulsation output of the heart beat in real time, that is, to assist the blood pump in generating a pulsating flow synchronized with the natural heart beat, thereby effectively and reliably maintaining the patient's life safety.

A vascular implant is provided for increasing the efficiency of blood flow through an aorta. The vascular implant includes a tubular shunt having a lumen for allowing blood to pass between an aorta and an inferior vena cava. An expandable reservoir is sized for placement in the inferior vena cava. The reservoir has a first region coupled to the tubular shunt and may include a second region formed with an exit port for allowing some blood to escape the reservoir into the inferior vena cava. The exit port reduces the possibility of stagnation in the reservoir. High pressure blood from the aorta temporarily passes through the tubular shunt and into the reservoir, such as during systole. When blood pressure reduces in the aorta, blood from the reservoir passes from the reservoir and through the shunt where it reenters the aorta, such as during diastole.

Apparatus and methods for repairing a cardiac valve, e.g., a tricuspid valve, are provided. The apparatus may include a prosthetic device coupled to an elongated support to suspend and maintain the prosthetic device within the cardiac valve. The support may include a proximal elongated shaft detachably coupled, in a delivery state, to a distal elongated shaft coupled to the prosthetic device. The proximal elongated shaft may detach from the distal elongated shaft at a detachment area within the patient responsive to actuation and components of the distal elongated shaft may lock to implant the prosthetic device and the distal elongated shaft within the patient. The prosthetic device may be formed of biocompatible material coupled to a frame, and may have prosthetic leaflets that allows blood to flow through in one direction during a phase of the cardiac cycle (e.g., diastole) but prevent blood regurgitation during the other phase (e.g., systole).

The disclosure provides a device for non-invasive blood pressure measurement comprising a blood pressure cuff positioned around a limb with an optical sensor integrated into the distal end. The optical sensor comprises a transmission optical sensor with light source and detector on opposite sides of a digit distal to the inflatable portion. A processing device controls cuff inflation and deflation while capturing successive optical plethysmographic waveforms during deflation. The processing device high-pass filters waveforms to produce filtered signals with equal area above and below baseline, multiplies corresponding points of filtered waveforms to generate product values, and sums products to determine concordance measures. The device detects initial returning pulsations by identifying when initial low-amplitude optical pulsations have same shape as larger amplitude pulsations during deflation. Systolic blood pressure is determined when concordance measures indicate shape concordance between initial and subsequent optical pulsations. The device measures blood pressure and calculates ankle-brachial indices.

A non-contact cardiogram measurement method is disclosed. The method includes: measuring, by a Doppler radar or a pulse radar, a distance change between the radar and a skin surface through an electromagnetic wave, a light wave and a sound wave; deriving a displacement curve indicating a change in a human heart volume; taking first-order and second-order derivations of the displacement curve to acquire velocity and acceleration curves; taking zero points and extreme points of the velocity and acceleration curves as velocity and acceleration information, and as characteristic points of different stages of atrial and ventricular systole and diastole; acquiring time, volume change, velocity and acceleration information of atrial and ventricular systole and diastole in a cardiac cycle. The present disclosure features low cost and low radiation hazard, avoids direct contact with the human body, and provides a convenient and easy way for daily cardiac diagnostic measurement of special patients.