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47 results about "Afterload" patented technology
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Afterload is the pressure the heart must work against to eject blood during systole (ventricular contraction). Afterload is proportional to the average arterial pressure. As aortic/pulmonary pressure increases, the afterload on the left/right ventricle increase respectively. Afterload changes in order to adapt to the continually changing demands on an animal's cardiovascular system. Afterload is proportional to mean systolic blood pressure and is measured in millimeters of mercury (mm Hg).
Heart support to prevent ventricular remodeling
InactiveUS6887192B1Reducing end-diastolic diameterRelieve stressHeart valvesControl devicesSystoleCardiac functioning
This is a support device that prevents, reduces, and delays remodeling of diseased cardiac tissue, and also decreases the impact of such remodeling on collateral tissue is disclosed. The invention further reinforces abnormal tissue regions to prevent over-expansion of the tissue due to increased afterload and excessive wall tension. As a result, the support device prevents phenomenon such as systolic stretch from occurring and propagating. The support structure maintains and restores diastolic compliance, wall motion, and ejection fraction to preserve heart functionality. As such, the support device prevents and treats cardiomyopathy and congestive heart failure.
Owner:CONVERGE MEDICAL
Non-invasive method and device to monitor cardiac parameters
Owner:HIRSH ROBERT
Implantable heart assist system and method of applying same
InactiveUS7125376B2RevitalizeReduce energy inputSpecific fluid pumpsOther blood circulation devicesAfterloadCatheter
An extracardiac pumping for supplementing the circulation of blood, including the cardiac output, in a patient without any component thereof being connected to the patient's heart, and methods of using same. One embodiment of the intravascular extracardiac system comprises a pump with inflow and outflow conduits that are sized and configured to be implantable intravascularly through a non-primary vessel, whereby it may positioned where desired within the patient's vasculature. The system comprises a subcardiac pump that may be driven directly or electromagnetically from within or without the patient. The pump is configured to be operated continuously or in a pulsatile fashion, synchronous with the patient's heart, thereby potentially reducing the afterload of the heart. In another embodiment, the system is positioned extracorporeally, with the inflow conduit and outflow conduit applied percutaneously to a non-primary vessel for circulating blood to and from the non-primary vessel or between the non-primary vessel and another blood vessel within the patient's vasculature.
Owner:TC1 LLC
Method and device to administer anesthetic and or vosactive agents according to non-invasively monitored cardiac and or neurological parameters
InactiveUS20090124867A1Efficiently safely teachingPumping capacity is overwhelmedMedical simulationRespiratorsCardiac cycleWhole body
A method of and a device for non-invasively measuring the neurological depressed state and the hemodynamic state of a human patient and involving steps and units of non-invasively measuring EEG, cardiac cycle period, electrical-mechanical interval, mean arterial pressure, and ejection interval and converting the EEG into a neurological index as well as converting the measured electrical-mechanical interval, mean arterial pressure and ejection interval into the cardiac parameters such as Preload, Afterload and Contractility, which are the common cardiac parameters used by an anesthesiologist. A general anesthetic is administered based upon the converted neurological index. A vasoactive agent is independently administered based upon the converted cardiac parameters as necessary in order to restore cardiovascular homeostasis in the patient. The converted neurological and hemodynamic state of a patient are displayed on a screen as an index value and a three-dimensional vector with each of its three coordinates respectively representing Preload, Afterload and Contractility. Therefore, a medical practitioner looks at the screen and quickly obtains the important and necessary information.
Owner:THE COOPER HEALTH SYST
Implantable heart assist system and method of applying same
InactiveUS20060264695A1Reduce loadPermitting the heart to recover during useSpecific fluid pumpsOther blood circulation devicesAfterloadCatheter
Owner:VIOLE ANTHONY +7
Method and apparatus for assessing and treating myocardial wall stress
InactiveUS6965797B2Prevent and reverse myocardial remodelingHeart stimulatorsDiagnostic recording/measuringSystoleElectric stimulation therapy
An apparatus and method for assessing myocardial wall stress is disclosed. The method may be used in conjunction with electro-stimulatory therapy for preventing or reversing ventricular remodeling. In such therapy, one or more stimulatory pulses are delivered to the heart such that a stressed region of the myocardium is pre-excited relative to other regions, thereby subjecting the stressed region to a lessened preload and afterload during systole. The unloading of the stressed myocardium over time effects reversal of undesirable ventricular remodeling.
Owner:CARDIAC PACEMAKERS INC
Implantable heart assist system and method of applying same
InactiveUS20060270894A1Reduce loadPermitting the heart to recover during useSpecific fluid pumpsOther blood circulation devicesAfterloadCatheter
An extracardiac pumping for supplementing the circulation of blood, including the cardiac output, in a patient without any component thereof being connected to the patient's heart, and methods of using same. One embodiment of the intravascular extracardiac system comprises a pump with inflow and outflow conduits that are sized and configured to be implantable intravascularly through a non-primary vessel, whereby it may positioned where desired within the patient's vasculature. The system comprises a subcardiac pump that may be driven directly or electromagnetically from within or without the patient. The pump is configured to be operated continuously or in a pulsatile fashion, synchronous with the patient's heart, thereby potentially reducing the afterload of the heart. In another embodiment, the system is positioned extracorporeally, with the inflow conduit and outflow conduit applied percutaneously to a non-primary vessel for circulating blood to and from the non-primary vessel or between the non-primary vessel and another blood vessel within the patient's vasculature.
Owner:VIOLE ANTHONY +7
Apparatus and method for reversal of myocardial remodeling with electrical stimulation
An apparatus and method for reversing ventricular remodeling with electro-stimulatory therapy. A ventricle is paced by delivering one or more stimulatory pulses in a manner such that a stressed region of the myocardium is pre-excited relative to other regions in order to subject the stressed region to a lessened preload and afterload during systole. The unloading of the stressed myocardium over time effects reversal of undesirable ventricular remodeling.
Owner:CARDIAC PACEMAKERS INC
Cardiac stimulation at high ventricular wall stress areas
An apparatus and method for reversing ventricular remodeling with electro-stimulatory therapy. A ventricle is paced by delivering one or more stimulatory pulses in a manner such that a stressed region of the myocardium is pre-excited relative to other regions in order to subject the stressed region to a lessened preload and afterload during systole. The unloading of the stressed myocardium over time effects reversal of undesirable ventricular remodeling.
Owner:CARDIAC PACEMAKERS INC
Non-invasive method and device to monitor cardiac parameters without use of electrical-mechanical interval
InactiveUS20070191724A1Easy to measureSimple processElectrocardiographyBlood flow measurement devicesDiastolic intervalCardiac cycle
A method of and a device for non-invasively measuring the hemodynamic state of a subject or a human patient involve steps and units of non-invasively or minimally invasively measuring cardiac cycle period, mean arterial pressure, stroke volume, diastolic interval and ejection interval and converting the measured mean arterial pressure, stroke volume, diastolic interval and ejection interval into the cardiac parameters such as Preload, Afterload and Contractility, which are the common cardiac parameters used by an anesthesiologist. In the current invention, the use of electrical-mechanical interval has been eliminated for various advantageous reasons. The converted hemodynamic state of a patient is displayed on a screen as a three-dimensional vector with each of its three coordinates respectively representing Preload, Afterload and Contractility. Therefore, a medical practitioner looks at the screen and—quickly obtains the important and necessary information.
Owner:HIRSH ROBERT
Cardiac stimulation at high ventricular wall stress areas
InactiveUS20050065568A1Heart stimulatorsDiagnostic recording/measuringSystoleElectric stimulation therapy
An apparatus and method for reversing ventricular remodeling with electro-stimulatory therapy. A ventricle is paced by delivering one or more stimulatory pulses in a manner such that a stressed region of the myocardium is pre-excited relative to other regions in order to subject the stressed region to a lessened preload and afterload during systole. The unloading of the stressed myocardium over time effects reversal of undesirable ventricular remodeling.
Owner:CARDIAC PACEMAKERS INC
Implantable hemodynamic monitor and methods for use therewith
Provided herein are implantable systems that include an implantable photoplethysmography (PPG) sensor, which can be used to obtain an arterial PPG waveform. In an embodiment, a metric of a terminal portion of an arterial PPG waveform is determined, and a metric of an initial portion of the arterial PPG waveform is determined, and a surrogate of mean arterial pressure is determined based on the metric of the terminal portion and the metric of the initial portion. In another embodiment, a surrogate of diastolic pressure is determined based on a metric of a terminal portion of an arterial PPG waveform. In a further embodiment, a surrogate of cardiac afterload is determined based on a metric of a terminal portion of an arterial PPG waveform.
Owner:PACESETTER INC
Heart support to prevent ventricular remodeling
InactiveUS20050113635A1Reducing end-diastolic diameterRelieve stressHeart valvesControl devicesSystoleCardiac functioning
This is a support device that prevents, reduces, and delays remodeling of diseased cardiac tissue, and also decreases the impact of such remodeling on collateral tissue is disclosed. The invention further reinforces abnormal tissue regions to prevent over-expansion of the tissue due to increased afterload and excessive wall tension. As a result, the support device prevents phenomenon such as systolic stretch from occurring and propagating. The support structure maintains and restores diastolic compliance, wall motion, and ejection fraction to preserve heart functionality. As such, the support device prevents and treats cardiomyopathy and congestive heart failure.
Owner:CONVERGE MEDICAL
Method and system for determining cardiac performance
InactiveUS20100152547A1Determine cardiac performanceReduces and eliminates disadvantageCatheterSensorsAfterloadDeterminant
Methods and associated algorithms for determining cardiac and / or cardiovascular performance that are based on at least one cardiac function determinant associated with or at least in part, reflective of preload, contractility and afterload.
Owner:CARDIAC PROFILES
External left ventricular assist device for treatment of congestive heart failure
InactiveUS20080045866A1Lower blood pressureAvoid excessive volumeElectrotherapyPneumatic massageLeft ventricular sizeCongestive heart failure chf
The invention provides a treatment for congestive heart failure (CHF) in a patient. At least one pressure applicator is arranged externally around a body segment of the patient. Negative pressure, relative to atmospheric pressure, is applied to the body segment of the patient during cardiac systole using the pressure applicator, thereby reducing ventricular afterload in the patient. The negative pressure to the body segment of the patient is removed during cardiac diastole.
Owner:RASTEGAR JAHANGIR +1
Non-invasive method and device to monitor cardiac parameters without use of electrical-mechanical interval
InactiveUS7761141B2Easy to measureSimple processElectrocardiographyBlood flow measurement devicesDiastolic intervalCardiac cycle
A method of and a device for non-invasively measuring the hemodynamic state of a subject or a human patient involve steps and units of non-invasively or minimally invasively measuring cardiac cycle period, mean arterial pressure, stroke volume, diastolic interval and ejection interval and converting the measured mean arterial pressure, stroke volume, diastolic interval and ejection interval into the cardiac parameters such as Preload, Afterload and Contractility, which are the common cardiac parameters used by an anesthesiologist. In the current invention, the use of electrical-mechanical interval has been eliminated for various advantageous reasons. The converted hemodynamic state of a patient is displayed on a screen as a three-dimensional vector with each of its three coordinates respectively representing Preload, Afterload and Contractility. Therefore, a medical practitioner looks at the screen and—quickly obtains the important and necessary information.
Owner:HIRSH ROBERT
Apparatus and method for reversal of myocardial remodeling with electrical stimulation
An apparatus and method for reversing ventricular remodeling with electro-stimulatory therapy. A ventricle is paced by delivering one or more stimulatory pulses in a manner such that a stressed region of the myocardium is pre-excited relative to other regions in order to subject the stressed region to a lessened preload and afterload during systole. The unloading of the stressed myocardium over time effects reversal of undesirable ventricular remodeling.
Owner:CARDIAC PACEMAKERS INC
Method and system of determining cardiac contractility
A method and system is provided for determining the cardiac contractility of a cardiovascular system. The method includes utilizing values representing stroke volume, preload, and afterload to calculate the cardiac contractility. The calculation may include a mathematical relationship in which the cardiac contractility is represented by a first edge of a tetrahedron, the preload is represented by a second edge of the tetrahedron, the afterload is represented by a third edge of the tetrahedron, and the stroke volume is represented by the volume of the tetrahedron. A display apparatus is also provided. The display apparatus includes a schematic representation of a tetrahedron and indicia indicating that the cardiac contractility, the preload, the afterload, and the stroke volume are represented by mutually distinct parameters of the tetrahedron.
Owner:PROYECTO TECNICO R 2000 CA
Novel closestool
The invention discloses a novel closestool. A seat ring of the closestool is in a saddle type; the height difference between the lowest points of the upper end surface and the lower end surface of the seat ring is 55 to 60mm; the length of the seat ring is 280 to 290mm; the width of the seat ring is 350 to 360mm; the length of a seat ring hole formed in the seat ring is 230 to 250mm; the width of the seat ring hole is 170 to 190mm; an included angle between a connecting line between the lowest point of the lower end surface and the highest point of the front end of the upper end surface of the seat ring, and the horizontal tangent line of the lowest point of the lower end surface is 15 to 20 degrees; an included angle between the connecting line between the lowest point of the lower end surface and the highest point of the rear end of the upper end surface of the seat ring, and the horizontal tangent line of the lowest point of the lower end surface is 30 to 45 degrees. The novel closestool has the advantages that in the use process, the lower limbs naturally droop; the skeletal muscle is relaxant; the returned blood volume is reduced; the afterload of the heart is reduced; the elevation-angle-increase sitting posture defecation is realized, so that the defecation body position is comfortable and smooth; the novel closestool conforms to the defecation habit; the defecation time is shortened, so that the constipation occurrence rate is reduced.
Owner:当代五环(北京)文化发展中心 +1
Therapeutic and surgical treatment method for providing cardiopulmonary and circulatory assist device
The present disclosure relates to a therapeutic method for improving the hemodynamics, the overall microcirculation in organs, and the restoration and preservation of deficient endothelial function in a patient, the method includes maintaining blood circulation in the patient's veins and arteries and temporarily relieving the heart of its pumping function. Relief may be accomplished by increasing the preload of the right ventricle so as to improve oxygenation of the myocardium and its contractility, reducing and diffusing regular pulsations in the proximity of the aortic root so as to improve the hemodynamics of the left ventricle of the heart, and / or mechanically stimulating the endothelium by shear forces so as to reduce systemic and pulmonary afterload.
Owner:WU GUI FU +1
Non-invasive method and device to monitor cardiac parameters
A method of and a device for non-invasively measuring the hemodynamic state of a subject or a human patient involve steps and units of non-invasively measuring cardiac cycle period, electrical-mechanical interval, mean arterial pressure, and ejection interval and converting the measured electrical-mechanical interval, mean arterial pressure and ejection interval into the cardiac parameters such as Preload, Afterload and Contractility, which are the common cardiac parameters used by an anesthesiologist. The converted hemodynamic state of a patient is displayed on a screen as a three-dimensional vector with each of its three coordinates respectively representing Preload, Afterload and Contractility. Therefore, a medical practitioner looks at the screen and quickly obtains the important and necessary information.
Owner:HIRSH ROBERT
Novel device and method to measure ventricular arterial coupling and vascular performance
A device and method for analyzing of a disturbed pattern of pulse wave front results in a non-invasive, real-time diagnostic tool of arterial vascular performance on both a global and regional scale. The device provides a single number quantifying how well the arterial tree as a whole is coupled to receive and distribute a stroke volume of a single heartbeat. Changing heart rate, contractility, volume status, and afterload will change stroke volume and ejection time. Different vasculatures with different properties (e.g., size and intrinsic stiffness) will be best matched for different stroke volumes and ejection times to provide optimal coupling. The device will allow finding the optimal set of parameters for individual patient.
Owner:THE JOHN HOPKINS UNIV SCHOOL OF MEDICINE
Therapeutic and surgical treatment method for providing cardiopulmonary and circulatory assist device
The present disclosure relates to a therapeutic method for improving the hemodynamics, the overall microcirculation in organs, and the restoration and preservation of deficient endothelial function in a patient, the method includes maintaining blood circulation in the patient's veins and arteries and temporarily relieving the heart of its pumping function. Relief may be accomplished by increasing the preload of the right ventricle so as to improve oxygenation of the myocardium and its contractility, reducing and diffusing regular pulsations in the proximity of the aortic root so as to improve the hemodynamics of the left ventricle of the heart, and / or mechanically stimulating the endothelium by shear forces so as to reduce systemic and pulmonary afterload.
Owner:WU GUI FU +1
Implantable hemodynamic monitor and methods for use therewith
Provided herein are implantable systems that include an implantable photoplethysmography (PPG) sensor, which can be used to obtain an arterial PPG waveform. In an embodiment, a metric of a terminal portion of an arterial PPG waveform is determined, and a metric of an initial portion of the arterial PPG waveform is determined, and a surrogate of mean arterial pressure is determined based on the metric of the terminal portion and the metric of the initial portion. In another embodiment, a surrogate of diastolic pressure is determined based on a metric of a terminal portion of an arterial PPG waveform. In a further embodiment, a surrogate of cardiac afterload is determined based on a metric of a terminal portion of an arterial PPG waveform.
Owner:PACESETTER INC
FFR rapid calculation system model based on zero-dimensional hemodynamic model
PendingCN111241759ASmall amount of calculationImprove simulation speedImage enhancementImage analysisCoronary arteriesBlood flow
Owner:BEIJING UNIV OF TECH
Extra-aortic ballon eounterpulsation type heart chamber auxiliary pump
InactiveCN101485907AReduce work loadReduce ejection resistanceSuction devicesProsthesisIntra-aortic balloon counterpulsationHeart chamber
The invention provides a lateral aortic balloon counterpulsation cardiac ventricle donkey pump, which consists of a hard shell, a balloon, an air inlet pipe which connects a drive unit and the lateral aortic balloon counterpulsation cardiac ventricle donkey pump, and a blood pipe which connects a posterior aorta and a cardiac ventricle donkey pump and is used for blood to flow, wherein the balloon splits the hard shell into an air receiving cavity and a blood receiving cavity. Compared with the prior intra-aortic balloon counterpulsation pump, the lateral aortic balloon counterpulsation cardiac ventricle donkey pump has the advantages of simple structure, low production cost, convenient use and high use safety, not only can be arranged inside a thoracic cavity but also can be arranged in vitro during operation and postoperative recovery, has good effects of lightening the afterload of a left ventricle and improving blood supply of coronary arteries because the mounting position of the lateral aortic balloon counterpulsation cardiac ventricle donkey pump is close to the heart, and has stable treatment effect. Moreover, the blood enters in and out from the same pipe, so that thrombus is difficult to generate.
Owner:姬尚义
Corynoxeine and application of isomer thereof in preparing medicines
InactiveCN101991573ARaise the excitement thresholdAccurate massOrganic active ingredientsMetabolism disorderVentricular tachycardiaAngina
The invention belongs to the traditional Chinese medicine field, and relates to corynoxeine and an application of an isomer of the corynoxeine in preparing medicines. In the invention, the results of animal experiments prove that the corynoxeine and the isomer thereof have the effects of expanding vessels and lowering blood pressure, and can be used for preparing the medicines for expanding the vessels and lowering the blood pressure; the corynoxeine and isocorynoxeine have the effects of expanding the vessels, lowering heart afterload, lightening heart burden and decreasing myocardial oxygen consumption, and can be used for preparing anti-angina pectoris medicines; the corynoxeine has the effects of negative myodynamia, directly decreasing the myocardial oxygen consumption, and doubly lowering the myocardial oxygen consumption; the corynoxeine and the isocorynoxeine have the effects of improving the ventricular muscle excited threshold and lowering the ventricular muscle contraction frequency, can be used for treating ventricular tachycardia, and can be used as a quality identification uncaria and tagged molecules of the ffective parts of the corynoxeine and the isocorynoxeine.
Owner:FUDAN UNIV
Afterload device for a beating heart during examination thereof
ActiveUS10405756B2Mitigate, alleviate or eliminate onePharmaceutical containersMedical devicesSystoleAfterload
An examination device for a heart. An afterload device connected to the aorta provides a counter-pressure by an annular space delimited between a rigid cylinder and an elastic tube inserted in the rigid cylinder. The annular space comprises a compressible medium, such as air, nitrogen gas or carbon dioxide and is connected to a reservoir providing a predetermined pressure corresponding to a diastolic pressure. The reservoir is connected to the annular space via a restriction and a back-flow valve. During diastole, the annular space is inflated by the reservoir and provides a diastolic counter pressure for providing coronary flow. During systole, the ejected fluid from the heart ventricle displaces the medium inside the annular space through the restriction to the reservoir, thereby removing energy from the fluid. The compressible medium forms a compliance. Also, there is a preload device comprising a vertical collapsible tube for preload of the atrium.
Owner:XVIVO PERFUSION
Test bench assembly for the simulation of cardiac surgery and/or interventional cardiology operations and/or procedures
A test bench assembly for simulating cardiac surgery includes a passive heart having at least one pair of cardiac chambers with an atrial chamber and a ventricular chamber. A reservoir is adapted to house working fluid. A pressure generator fluidically connects both to the ventricular chamber of the passive heart and to the reservoir. A pressure regulation device provides working fluid in input to the atrial chamber with preload pressure, and working fluid in output from the ventricular chamber with afterload pressure. The pressure regulation device fluidically connects both to the atrial chamber of the passive heart and to the ventricular chamber of the passive heart. The pressure regulation device has a single compliant element for each pair of cardiac chambers, which provides working fluid with both preload, and afterload pressures.
Owner:POLITECNICO DI MILANO +1
A high-flow pulsating electromagnetic blood pump and a left ventricular counterpulsation assisting system including the same
InactiveCN109157686AIncrease powerIncrease afterloadElectrocardiographyOther blood circulation devicesMagnetic tension forceLeft ventricular size
The invention discloses a high-flow pulsating electromagnetic blood pump, which comprises a mounting bracket. At least two magnetic pushing devices mounted on the support surface, the magnetic pushingdevices comprising a drive coil, a permanent magnet piston, a two-way joint, an inner bag and a magnetic shielding cylinder; At least one set of linkage assemblies for linkage of permanent magnet pistons in two of the magnetic propulsion devices of the same set reciprocating alternately; A processor for controlling a control circuit of the driving coil by a set rhythm or according to an electrocardiogram signal of a human body surface; And an electrocardiogram electrode for detecting and transmitting a body surface electrocardiogram signal of the human body to the processor. The invention integrates a plurality of magnetic pushing devices and is linked by the linkage components in two groups, thereby effectively reducing heat generation, increasing the power of the whole machine in multiple, simultaneously increasing the flow rate, and effectively improving the working condition. It can also be controlled according to extracorporeal electrocardiogram signals, which can avoid increasing the afterload of myocardium in systolic phase.
Owner:SHANGHAI YANGPU SHIDONG HOSPITAL
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