28 results about "Electric stimulation therapy" patented technology

The invention discloses a multifunctional wound patch combined with electrical stimulation therapy and a preparation method and application thereof, and relates to the technical field of medical materials, and the multifunctional wound patch comprises a double-layer electrostatic spinning fiber membrane, a conductive ink layer and a conductive hydrogel layer. S-shaped concentric circle conductive electrode pairs written by conductive ink are integrated on the surface (directly in contact with the wound) of the hydrophobic fiber layer, and square conductive ports with corresponding sizes can be drawn at the tail ends of the two electrodes as required. And the surface of the conductive electrode pair is packaged by conductive hydrogel with an antibacterial function. An external electric signal can be transmitted to the electrode pair of the patch through the conductive port of the electrode pair, and then acts on a wound through the conductive hydrogel layer, so that on-demand electrical stimulation treatment on the wound is realized. According to the multifunctional wound patch combined with the electrical stimulation therapy, discharge of redundant seepage can be achieved, and it is guaranteed that the wound environment is good; the curcumin-loaded medicine has the effects of resisting bacteria, resisting oxidation and promoting healing on wounds.

A pathway planning apparatus includes a processor configured to plan a pathway for implanting an electrode lead into a brain of a patient, wherein the planned pathway satisfies the following condition: if the electrode lead is implanted into the brain of the patient according to the pathway, the electrode lead is capable of simultaneously making contact with an anterior limb of an internal capsule and a nucleus accumbens in one hemisphere of a brain of the patient. The pathway planned by the pathway planning apparatus enables the electrode lead to simultaneously deliver the electrical stimulation to the anterior limb of the internal capsule and the nucleus accumbens such that a combined electrical stimulation therapy is achieved, which has a better effect of treating diseases such as addictive behaviors, depressive disorders, and obsessive-compulsive disorders.

An example method includes delivering one or more electrical stimulation signals to a patient, sensing a composite stimulation-evoked signal comprising a composite of signals generated by one or more signal sources in response to the one or more electrical stimulation signals, and controlling delivery of electrical stimulation therapy to the patient based on the composite stimulation-evoked signal.

Techniques are disclosed for defining a homeostatic window for controlling delivery of electrical stimulation therapy to a patient. In one example, a method includes generating and delivering electrical stimulation therapy to tissue of a patient via electrodes. Further, the method includes adjusting a level of a parameter of the electrical stimulation therapy such that a signal of the patient is not less than a lower bound and not greater than an upper bound. The lower bound is determined to be the magnitude of the signal while receiving electrical stimulation therapy sufficient to reduce one or more symptoms of a disease while the patient was receiving medication for reduction of the one or more symptoms. Further, the upper bound is determined to be the magnitude of the signal while receiving electrical stimulation therapy sufficient to reduce the one or more symptoms when the patient was not receiving the medication.

Systems and methods for coordination of medication adjustment for neuromodulation therapy are disclosed. An exemplary system comprises a processing system. The processing system may receive medication data associated with administration of medication from a. patient in an absence of administering electrostimulation to the patient. The processing system may receive stimulation data, associated with administration of electrostimulation therapy to the patient while the patient is not being administered medication. The processing system may compare the medication data to the stimulation data to provide a comparison. The processing system may generate a medication schedule and an electrostimulation schedule based on the comparison to increase efficacy of therapy and minimize side effects.

The invention relates to the technical field of electrical stimulation treatment, in particular to an electrical stimulation medical device for acupoint electric massage recovery, which comprises a positioning cover, an electrical stimulation assembly, a lifting ring, a rotary ring and a plurality of groups of massage assemblies, the massage device comprises a rotary nut, an electrode block and an operation shaft, the lifting ring is arranged in the positioning cover, the rotary ring is rotationally installed on the lifting ring, and the multiple massage assemblies are evenly arranged along the circumferential side of the rotary ring and comprise positioning frames, sliding wedge blocks and massage columns. When the electrode blocks in the electrical stimulation assembly are driven by the rotation of the operation shaft to be separated from the skin of the patient, the multiple massage assemblies can be driven to make contact with the skin of the patient at the moment, and muscles, subjected to electrical stimulation, at acupuncture points are massaged and relaxed.

The present invention discloses a multifunctional wound patch for combined electrical stimulation therapy, as well as its preparation method and application, and relates to the field of medical material technology. The multifunctional wound patch comprises a double-layer electrospun fiber membrane, a conductive ink layer, and a conductive hydrogel layer. The surface of the hydrophobic fiber layer (the side directly contacting the wound) is integrated with a pair of serpentine concentric conductive electrodes written with conductive ink, and the ends of the two electrodes can be drawn with square conductive ports of corresponding sizes as needed. The surface of the conductive electrode pair is encapsulated with a conductive hydrogel with antibacterial function. External electrical signals can be transmitted to the electrode pair of the patch through the conductive ports of the electrode pair, and then act on the wound through the conductive hydrogel layer to achieve on-demand electrical stimulation treatment of the wound. The multifunctional wound patch for combined electrical stimulation therapy prepared by the present invention can achieve the discharge of excess exudate and ensure a good wound environment; the loaded curcumin drug has antibacterial, antioxidant, and healing effects on the wound.

Techniques are disclosed for delivering electrical stimulation therapy to a patient. In one example, a medical system delivers electrical stimulation therapy to a tissue of the patient via electrodes. The medical system determines a first change of a first sensed signal of the patient to movement by the patient and a second change of a second sensed signal of the patient to the movement by the patient. Based on the first change and the second change, the medical system selects one of the first sensed signal and the second sensed signal of the patient for controlling the electrical stimulation therapy. The medical system adjusts a level of at least one parameter of the electrical stimulation therapy based on the selected one of the first sensed signal and the second sensed signal.

This document describes a technique for evaluating therapy in patients with Restless Legs Syndrome (RLS). The technique can involve receiving a metric indicative of drug therapy administration and first sensor data that reflects leg movement or sleep quality during a desired relief period from RLS symptoms. A drug therapy efficacy indicator can be generated, such as based on the first sensor data and isolated from electrostimulation therapy effects. Such an indicator can assist a user or processes in evaluating the therapy's effectiveness for the patient. Such a technique can provide a systematic approach to assess the efficacy of drug therapy in managing RLS symptoms, enabling personalized treatment adjustments and improved patient outcomes.

The present invention relates to non-excitatory electrical heart failure therapy as a therapy for Heart failure with preserved ejection fraction.

Techniques are disclosed for implementing the use of electrically evoked compound action potentials (ECAPs) to adaptively adjust parameters of high frequency electrical stimulation. In one example, a medical device delivers electrical stimulation therapy comprising a train of electrical stimulation pulses to a patient, wherein the train of electrical stimulation pulses comprises a pulse frequency greater than or equal to 500 Hertz. After delivering the train of electrical stimulation pulses, the medical device ceases delivery of the high frequency electrical stimulation therapy for a predetermined period of time. During the predetermined period of time, the medical device senses an ECAP from the patient and determines, based on the sensed ECAP, a value of a parameter at least partially defining the train of electrical stimulation pulses. Responsive to the predetermined period of time elapsing, the medical device resumes delivery of the high frequency electrical stimulation according to the determined parameter.

A leadless implantable medical device (IMD) with electrodes near tissue of a patient and a rechargeable energy storage device. Power receiving circuitry receives electrical energy a wireless power transmitting device. The power receiving circuitry includes one or more secondary coils arranged to efficiently receive the wireless power when the primary coil is at any angle relative to the IMD. The IMD includes a non-conductive, hermetically sealed housing that encloses the device circuitry, including the rechargeable energy storage device, power receiving circuitry, processing circuitry, electrical stimulation circuitry and other components to perform the functions of the IMD. The housing may include one or more conductive ferrules which may provide the hermetic seal for the housing as well as act as an electrode to sense bioelectrical signals and / or deliver electrical stimulation therapy.

Systems and methods for coordination of medication adjustment for neuromodulation therapy are disclosed. An exemplary system comprises a processing system. The processing system may receive medication data associated with administration of medication from a patient in an absence of administering electrostimulation to the patient. The processing system may receive stimulation data associated with administration of electrostimulation therapy to the patient while the patient is not being administered medication. The processing system may compare the medication data to the stimulation data to provide a comparison. The processing system may generate a medication schedule and an electrostimulation schedule based on the comparison to increase efficacy of therapy and minimize side effects.

A method of providing electrical stimulation therapy to a patient according to one embodiment includes generating an un-tuned electrical noise signal by at least one noise generator, partitioning the un-tuned electrical noise signal into a plurality of discrete frequency bands having corresponding bandwidths, delivering the un-tuned electrical noise signal through one or more electrodes to the patient to target the patient's central or peripheral nervous system, adjusting, for each of a plurality of selected frequency bands, an amplitude of the voltage or current of the un-tuned electrical noise signal within a corresponding frequency band to generate an adjusted electrical stimulation signal based on feedback received from the patient, wherein the adjusted electrical stimulation signal includes a plurality of local maxima and a plurality of local minima, and delivering the adjusted electrical stimulation signal through the electrodes to provide electrical stimulation therapy to the patient.

The invention relates to a vagus nerve stimulation device and a preparation method thereof. The vagus nerve stimulation device is suitable for being arranged at the neck of a human body to stimulate the vagus nerve of the neck and comprises an electrical stimulation unit, a thermal therapy unit and a hard base shell. The electrical stimulation unit comprises a pulse generation module and an electrode electrically connected with the pulse generation module; the thermal therapy unit is used for generating heat to act on the neck of a human body; the hard base shell is used for installing the electrode and the thermal therapy unit. Wherein the hard base shell bears the electrode and the thermal therapy unit and is arranged on the neck of a human body, so that the electrode is in contact with the neck skin to output an electrical stimulation signal to stimulate the vagus nerve of the neck, and the thermal therapy unit heats the electrode or the neck skin. According to the vagus nerve stimulation device provided by the invention, the treatment effect and the use experience are improved through the cooperation of the thermal therapy and the electrical stimulation therapy.

Devices, systems, and techniques are disclosed for delivering electrical stimulation therapy and / or sensing physiological signals via electrodes disposed on a deformable auxetic structure. For example, a system may include a structure including a pattern of repeating cells configured to transition the structure between a compact configuration and an expanded configuration. The structure may be substantially flat when in the compact configuration. The structure may define one or more three-dimensional profiles when in the expanded configuration. Each of the repeating cells may include a plurality of elements that have an increased distance between adjacent ones of the plurality of elements when in the expanded configuration compared to the compact configuration. One or more electrodes may be disposed on the structure.

A method for processing a physiological signal is provided. The method includes the following steps. A standard physiological signal as a first template to perform a first match filtering on an original physiological signal of a subject under test is used, thereby obtaining a first filtered physiological signal. A correlation evaluation on the first filtered physiological signal is performed and based on an evaluation result, whether interference has been sufficiently eliminated is determined. When determining that the interference has not been sufficiently eliminated, a personal physiological signal of the subject under test is used as a second template to perform a second match filtering on the first filtered physiological signal, thereby obtaining a second filtered physiological signal. A physiological parameter of the subject under test based on the second filtered physiological signal is generated.

A system may include a memory configured to store at least one feedback parameter that at least partially defines closed-loop control of one or more stimulation parameters that define electrical stimulation therapy. The system may further include processing circuity configured to receive a first signal indicative of a patient condition of a patient; determine, based on the first signal, an adjusted value of the at least one feedback parameter; receive sensed information representative of a second signal sensed from the patient; compare the sensed information to the adjusted value of the at least one feedback parameter; and control, based on the comparison of the sensed information to the adjusted value, stimulation circuitry to deliver the electrical stimulation therapy.

Systems and methods rely on feedback from an active medical device or devices (e.g., neurostimulator coupled to sensing and stimulation elements such as electrodes) to assess the effectiveness of a patient's drug regimen. Such reliance may include analyzing characteristics in physiological data acquired by the medical device(s), for example, in the form of responses evoked from the patient by electrical stimulation waveforms. Systems and methods further involved adjusting one or more parameters according to which a combination therapy consisting of at least a drug regimen and an electrical stimulation therapy are delivered to a patient, in an effort to optimize the therapeutic effect of the combination. The adjustments may be automatically by one or more implanted or external hosts working together or alone, and / or with the input of a physician.

The present invention relates to an electroceutical screening device and a screening method using same, respectively, wherein an electrical stimulation is applied, through the electrodes, to the cell clusters received in the channels, and the potentials of the cell clusters are measured so as to measure neural activity, and thus electrical stimulation tests are conducted in various ways, and by measuring conduction velocity according to the various electrical stimulation tests, conditions for electrical stimulation therapy are assessed.

In general, devices, systems, and techniques are described for determining periodicity metrics for electrical signals sensed from a patient. In one example, a system includes processing circuitry configured to receive, from sensing circuitry, a plurality of electric signals from a patient sensed over a time duration, determine characteristic values for the plurality of bioelectric signals, and determine, based on the characteristic values, a periodicity metric indicative of one or more repeating periods for the plurality of bioelectric signals. The processing circuitry can then control delivery of electrical stimulation therapy based on the periodicity metric.

Devices, systems, and techniques are described that use electric field imaging (often referred to as the sensed stimulation artifact representative of a delivered stimulus) as an informative feedback signal to provide closed loop control of electrical stimulation therapy. In some examples, the electric field imaging may be used in combination with other feedback signals, such as ECAP do monitor and adjust the delivered electrical stimulation therapy.

Systems and methods are described to support simulating the delivery of a therapy, such as an electrical stimulation therapy, to a patient. In one example, a simulation system is described to include a first model representing a patient and a second model representing a stimulation device. The second model interacts with the first model by providing one or more simulated electrical signals generated in accordance with a simulation scenario as inputs for processing by the first model. The simulation scenario may be defined and adjusted by a user of the simulation system.

Devices, systems, and techniques for controlling electrical stimulation therapy are described. In one example, a system is configured to deliver, via a first electrode combination, a first stimulation pulse to a portion of a spinal cord of a patient located caudally of a spinal cord injury location of the spinal cord of the patient; sense, via a second electrode combination, an evoked compound action potential (ECAP) signal elicited by the first stimulation pulse; identify, by processing circuitry, a characteristic of the ECAP signal; determine, by the processing circuitry and based on the characteristic of the ECAP signal, a therapy parameter value that at least partially defines a second stimulation pulse; and deliver the second stimulation pulse according to the determined therapy parameter value.

Techniques are disclosed for implementing the use of electrically evoked compound action potentials (ECAPs) to adaptively adjust parameters of high frequency electrical stimulation. In one example, a medical device delivers electrical stimulation therapy comprising a train of electrical stimulation pulses to a patient, wherein the train of electrical stimulation pulses comprises a pulse frequency greater than or equal to 500 Hertz. After delivering the train of electrical stimulation pulses, the medical device ceases delivery of the high frequency electrical stimulation therapy for a predetermined period of time. During the predetermined period of time, the medical device senses an ECAP from the patient and determines, based on the sensed ECAP, a value of a parameter at least partially defining the train of electrical stimulation pulses. Responsive to the predetermined period of time elapsing, the medical device resumes delivery of the high frequency electrical stimulation according to the determined parameter.