55 results about "Neurostimulation device" patented technology

An auditory neural interface device for sound perception by an individual that may be used as a hearing aid. The auditory neural interface device includes a receiver configured to receive sound signals, a processor operably connected to the receiver and configured to encode a received sound signal as a multi-channel neurostimulation signal, and a neurostimulation device operably connected to the processor and configured to apply the multi-channel neurostimulation signal to a neurostimulation electrode of the individual. The neurostimulation signal is configured to directly stimulate afferent sensory neurons of the central nervous system of the individual and thereby to elicit, for each channel of the neurostimulation signal, one or more non-auditory, preferably somatosensory, perceptions in a cortex area of the individual. Each channel of the neurostimulation signal is associated with a different non-auditory perception.

The invention discloses an ear nerve stimulator, and belongs to the technical field of biomedical engineering and nerve regulation and control. The device mainly comprises a plurality of flexible patches attached to the ear, ear electrodes arranged according to ear acupuncture points and embedded in the flexible patches, and a stimulator adopting a cross-ear design. And the flexible patch has biocompatibility and adhesion, so that comfortable and stable wearing is ensured. A control unit and a stimulation module are contained in the stimulator shell, and stimulation current parameters can be generated and accurately regulated and controlled. Through flexible fitting and precise acupoint electrode design, the defects that a traditional electrode is uncomfortable to wear, and a stimulation area is fixed and inaccurate are overcome. And the equipment is light and stable due to the ear-crossing structure. A selectable air pump and air bag mechanism further ensures the reliability of electric contact. The device can realize safe, accurate and comfortable ear vagus nerve stimulation, is suitable for treatment and rehabilitation of epilepsy, depression and other diseases, and has a wide application prospect.

A method of predictive analysis of one or more characteristics associated with multiple neurostimulators used by respective multiple users, the method comprising: processing at a first site first input data collected from a first plurality of neurostimulation devices and / or neurostimulation users, and generating first machine learning model data from the first input data, the first machine learning model data comprising first model parameters; processing at a second site second input data collected from a second plurality of neurostimulation devices and / or neurostimulation users, and generating second machine learning model data from the second input data, the second machine learning model data comprising second model parameters; processing the first model parameters and the second model parameters to generate third machine learning model data representative of at least one neurostimulation characteristic; and using the third machine learning model data to predict evolution of at least one neurostimulation characteristic.

Systems and techniques to determine programming of an implantable electrical neurostimulation device, through chronic pain treatment modeling that evaluates pain experience states and transitions for a patient. In an example, a system to determine programming of a neurostimulation device performs operations to: determine possible pathways to traverse pain experience states of a chronic pain condition, as the possible pathways provide respective paths among the states from a starting state to one or more intermediate states to a goal state; determine transition costs between the states used in the possible pathways, with respective pain experience states being associated with different pain management characteristics of neurostimulation therapy; identify a path of the possible pathways to reach the goal state, based on the transition costs and patient characteristics; and select programming parameters for the neurostimulation device, to provide neurostimulation therapy based on the identified path to achieve the goal state.

The utility model relates to the technical field of medical equipment, and provides a nerve stimulation acupuncture needle, which comprises a needle seat, a needle core, a conductor wire, a needle core, a needle core, a needle core, a needle core, a needle core, a needle core, a needle core, a needle core, a needle core and a needle core, the needle core and the conductor wire are electrically connected, and the needle seat is of an insulating material structure; the cannula is provided with a through hole, the cannula is arranged on the needle base and the needle core in a sleeving mode through the through hole, and scale marks are arranged on the outer side wall of the cannula and used for displaying the insertion depth of the needle core; the needle base and the needle core are slidably arranged along the through hole, and scale reference marks are arranged at the positions, close to the scale marks, of the needle base. During use, the needle core is slowly inserted into the subcutaneous part of a patient, the sleeve abuts against the skin of the patient, and at the moment, the needle base slides along the through hole of the sleeve. The scale mark pointed by the scale reference mark on the needle seat is the current depth of the needle core inserted into the subcutaneous part of the patient, and the sleeve with the scales helps a doctor to master the insertion depth. Meanwhile, the nerve stimulation acupuncture needle can be connected into a nerve stimulator, and a target nerve is searched through the nerve stimulator.

Disclosed is a neurostimulation system and method. A control unit controls a stimulus source to deliver neural stimuli via selected electrodes to a neural pathway according to a stimulus intensity parameter. An external computing device in communication with the neurostimulation device comprises a display and processor. The processor initialises the stimulus intensity parameter, and renders on the display a stimulation control and a graphical element adjacent the stimulation control. Upon user activation of the stimulation control, the processor ramps a value of the stimulus intensity parameter, while instructing the control unit to cause delivery of stimuli according to the ramping value of the stimulus intensity parameter. Upon user deactivation of the stimulation control, the processor ceases ramping the value of the stimulus intensity parameter. The graphical element is configured to dynamically indicate the ramping value of the stimulus intensity parameter; and indicate a discomfort threshold for the selected electrodes.

Systems and techniques to determine programming of an implantable electrical neurostimulation device, through chronic pain treatment modeling that evaluates pain experience states and transitions for a patient. In an example, a system to determine programming of a neurostimulation device performs operations to: determine possible pathways to traverse pain experience states of a chronic pain condition, as the possible pathways provide respective paths among the states from a starting state to one or more intermediate states to a goal state; determine transition costs between the states used in the possible pathways, with respective pain experience states being associated with different pain management characteristics of neurostimulation therapy; identify a path of the possible pathways to reach the goal state, based on the transition costs and patient characteristics; and select programming parameters for the neurostimulation device, to provide neurostimulation therapy based on the identified path to achieve the goal state.

A leadless neurostimulation device configured for implantation in a leg of a patient comprising a header with a first electrode and an elongated main body containing stimulation circuitry and a battery with a second electrode extending circumferentially around at least a portion of the main body. The electrode configuration proves greater volume of tissue activation with lower power requirements and improved battery efficiency.

1. Name of the product in this design: Walking Assistive Rehabilitation Device. 2. Purpose of this design: It is used in a walking rehabilitation device, which is a wearable functional neurostimulation instrument used for lower limb rehabilitation and recovery of muscles damaged by motor neurons. 3. The key design feature of this product is its shape. 4. The image or photograph that best illustrates the design's key points: 3D view 1. 5. Other circumstances requiring explanation: The human lower limb model is a supporting element and is not part of the content for which protection is sought.

The utility model relates to the technical field of medical instruments, and discloses a vagus nerve stimulator suspension device which comprises a protection box, a box cover, a plate sleeve, a connecting plate and a fixing assembly. A long bandage is fixed to the top end of one side of the protection box through a bolt, and a hook-and-loop fastener sub-face is sewn to one side of the long bandage; the short bandage is fixed to the bottom end of one side of the protection box through bolts, the hook-and-loop fastener female face is sewn to one side of the short bandage, the plate sleeve is fixedly arranged on the side, away from the long bandage, of the protection box, the top end of the plate sleeve is sleeved with the connecting plate, the box cover is fixedly arranged on one side of the connecting plate, and the fixing assemblies are arranged on the two sides of the plate sleeve. The fixing assembly comprises sleeves arranged on the two sides of the plate sleeve at equal intervals. The ear nerve stimulator is arranged in the protection box and is fixed on the shoulder of a user through the long bandage and the short bandage, so that the ear nerve stimulator can be effectively protected, the movement and movement of the user cannot be influenced after the ear nerve stimulator is fixed, and the ear nerve stimulator is suitable for wide popularization and use.

A method of controlling operation of a neurostimulation device comprises receiving, by the neurostimulation device, an indication of a physiological search area of a subject for delivering electrical neurostimulation and a prioritized search list of neurostimulation parameters for neurostimulation therapy delivered to the search area; delivering the neurostimulation therapy to the search area and varying the neurostimulation parameters according to the parameter priority, wherein a highest priority parameter is varied first while lower priority parameters are held constant; determining the optimum value of the highest priority parameter; delivering neurostimulation to the search area using the determined optimum value of the highest priority parameter and varying one or more lower priority parameters according to the parameter priority; and determining optimum lower priority parameters for the neurostimulation.

A leadless neurostimulation device configured for implantation in a leg of a patient comprising a header with a first electrode and an elongated main body containing stimulation circuitry and a battery with a second electrode extending circumferentially around at least a portion of the main body. The electrode configuration proves greater volume of tissue activation with lower power requirements and improved battery efficiency.

The present disclosure relates to a tinnitus suppression device, method, system and computer program. In some aspects, a tinnitus suppression device comprises a receiver module configured to receive sound signals, a processing module operably connected to a memory and to the receiver module, and a neurostimulation module operably connected to the processing module. In some aspects, the processing module and the neurostimulation module may be configured to determine a received sound signal that corresponds to a template stored in the memory, that is above a preconfigured threshold, preferably above a preconfigured threshold which is specific for the individual, or both. A multi-channel neurostimulation signal encoding the determined sound signal may be generated and applied to a neurostimulation device of the individual that may be configured to directly stimulate afferent sensory neurons of the central nervous system of the individual and thereby to elicit, for each channel of the neurostimulation signal, one or more non-auditory, preferably somatosensory, perceptions in a cortex area of the individual.

Systems and techniques are disclosed to evaluate a neurostimulation treatment provided from a neurostimulation device, based on freeform text analysis. In an example, a system or device to evaluate a neurostimulation treatment provided from a neurostimulation device is configured to perform operations that: obtain text content, originating from text or voice input of a human patient, which relates to a state of a human patient; identify a state of the human patient from natural language processing of the text content; obtain device data from the neurostimulation device; identify a state of the neurostimulation treatment of the human patient from the device data; associate the identified state of the human patient to the identified state of the neurostimulation treatment; and initiate an action for the neurostimulation treatment, based on the identified state of the human patient that is associated with the identified state of the neurostimulation treatment.

A system and method for automated neurostimulation programming uses machine learning to determine target stimulation or discard suboptimal parameters based on actual or anticipated clinical effects. The system includes processors to generate a database of previously acquired lead and / or brain images, tested stimulation settings and associated clinical effects. A region of interest surrounding at least one stimulation lead is identified. Stimulation settings linked to specific clinical effects, including beneficial or detrimental effects, are determined for the region of interest. A trained machine learning model identifies desirable, undesirable, target, or other stimulation parameter values for a new patient by classifying or regressing raw imaging data, from the region of interest. The model is trained to recommend settings that produce desired clinical effects. An output provides the target stimulation parameter values predicted to maximize therapeutic benefit and minimize side effects. This enables automated programming of neurostimulation devices through data-driven machine learning based on clinical outcomes.

The invention provides a multi-mode respiratory signal detection method and device and an implantable nerve stimulation device. The method comprises the following steps: extracting a multi-modal signal from a physiological signal of a target object; correspondingly generating a breathing waveform of the target object based on the multi-modal signal; and based on the availability of the multi-mode signal or the breathing waveform, adopting a corresponding breathing detection mode to identify the breathing characteristic of the target object from the breathing waveform. According to the method, on one hand, the breathing characteristics are analyzed in the preset breathing detection mode, and the accuracy of breathing monitoring can be improved; on the other hand, a respiration detection electrode does not need to be additionally added, and the applicability and the convenience are correspondingly improved.

A method of controlling operation of a neurostimulation device comprises receiving, by the neurostimulation device, an indication of a physiological search area of a subject for delivering electrical neurostimulation and a prioritized search list of neurostimulation parameters for neurostimulation therapy delivered to the search area; delivering the neurostimulation therapy to the search area and varying the neurostimulation parameters according to the parameter priority, wherein a highest priority parameter is varied first while lower priority parameters are held constant; determining the optimum value of the highest priority parameter; delivering neurostimulation to the search area using the determined optimum value of the highest priority parameter and varying one or more lower priority parameters according to the parameter priority; and determining optimum lower priority parameters for the neurostimulation.

Methods and devices for facilitating remote programming of an implanted neurostimulation device are provided herein. Such methods include establishing communication between an implanted pulse generator of the neurostimulation system and a remote device associated with a remote support entity through one or more intermediary devices. The intermediary devices can include any of: a patient remote, a charger, a specialized communicator device, a plug-in accessory, and a patient device to facilitate communication of patient and program information for a current neurostimulation therapy. The remote device determines or receives a program update of one or more parameters or a new neurostimulation program and updates the implantable pulse generator through the intermediary devices. The patient device and remote device can further include a software framework to facilitate communication between the patient and the remote support entity in a live programming session, as well as collecting subjective / objective patient information regarding the current treatment.

This document discusses a programming system for a neurostimulation device that provides neurostimulation energy to a patient according to programmable stimulation parameters. The programming system includes a wearable brain wave signal sensing device configured to sense brain wave signals of a patient produced in response to neurostimulation delivered using the neurostimulation device, and a second device. The second device includes a communication circuit to receive brain wave signal information from the wearable brain wave signal sensing device, processing circuitry, and a client application. The client application includes instructions executable by the processing circuitry and is configured to determine a sensed response to the neurostimulation of the patient indicated by the received brain wave signal information, compare the sensed response to a desired target response to the neurostimulation, and adjust the stimulation parameters of the neurostimulation device according to the comparing of the sensed response and the desired target response.

The present technology is generally directed to delivery systems for injected neurostimulation devices, and associated systems and methods. In some embodiments, a delivery system includes a body having an at least partially hollow interior; an adjustable sheath defining a lumen, the adjustable sheath including (i) a first portion positioned within the interior of the body and (ii) a second portion extending beyond the interior; and an actuation mechanism operably coupled to the body and the adjustable sheath. The actuation mechanism can be operable to move the adjustable sheath to change a length of the second portion. A user can operate the delivery system to position an implantable device at or near a target location within a patient. In some instances, the user may use image-based navigation and / or stimulation-based navigation to identify the position of the delivery system and / or the implantable device relative to target location.

Systems and methods for fabricating a metal core truss panel with seamlessly embedded features in accordance with embodiments of the invention are illustrated. One embodiment includes a method of treatment for major depressive disorder including obtaining functional imaging data of a patient's brain, identifying disordered lagged correlations between different brain regions using the functional imaging data, identifying a first region of a dorsolateral prefrontal cortex most strongly anti-correlated with an anterior cingulate cortex, identifying a second region of the dorsolateral prefrontal cortex abnormally receiving signals from the anterior cingulate cortex, generating a neurostimulation target as the overlap between the first region and the second region, and applying neurostimulation to the target using a neurostimulation device.

An external device configured to communicate with an implantable stimulator device implanted in a patient, comprising: control circuitry configured to: provide stimulation parameters for the patient to address a symptom of the patient, provide a schedule for the provision of scheduled boluses of stimulation for the patient, wherein each scheduled bolus comprises a first duration during which stimulation is applied to the patient in accordance with the stimulation parameters, wherein the scheduled boluses are separated by off times of a second duration when no stimulation is provided to the patient, receive at a first time an input at a graphical user interface of the external device to immediately provide an additional bolus of stimulation, and transmit instructions to cause the implantable stimulator device to provide at least the scheduled boluses to neural tissue of the patient according to the schedule.

The invention discloses a reference current calibration method for a nerve stimulation device. The reference current calibration method comprises the following steps: step 1, assuming a reference current value constant; 2, setting an output current, and generating voltage amplification through a 10-ohm load; step 3, calculating an actual reference current value by using an ADC function of the ENS001 chip; 4, changing the assumed reference current value constant into the actual reference current value calculated in the step 3; 5, repeating the steps 2-3, and calculating the actual reference current value obtained for the second time; 6, judging whether the difference between the actual reference current value obtained in the step 3 and the actual reference current value obtained for the second time in the step 5 is greater than 5%, and if the difference is greater than 5%, repeating the step 4 and the step 5; obtaining a first final reference current value until the difference is less than or equal to 5%; and step 7, the final reference current value is stored in the flash of the ENS001 chip. The reference current of the nerve stimulation device can be quickly and accurately determined, and the reference current is stored in a flash of a chip, so that the calibration precision and consistency of products are improved.

A balance prosthesis device for an individual including a sensor module configured to obtain a sensor signal indicative of a balance or equilibrium state of the individual, a processing module configured to determine at least one neurostimulation signal based at least in part on the obtained sensor signal, and a transmitter module configured to transmit the determined neurostimulation signal to a neurostimulation device of the individual. The neurostimulation signal is configured to elicit an artificial sensation in a specific sensory cortex area of the individual via directly stimulating afferent sensory axons of the central or peripheral nervous system of the individual targeting sensory neurons of the sensory cortex area not directly associated with vestibulocortical pathways of the individual. The elicited artificial sensation provides a balance indication to the individual in order to support, mimic, substitute or enhance the natural sense of balance of the individual.

The present invention is a neurostimulation treatment system, device, applicator, and methods of use to provide neurostimulation to a nerve. The device includes a wearable band that attaches to the patient's lower leg and ankle in a location proximate to the posterior tibial nerve. The wearable band includes a housing holding a microneedle electrode array which is extended to pierce the epidermis of the patient's ankle for a treatment session, and a control unit to power neurostimulation. Proper location of the wearable band proximate to the posterior tibial nerve may be assisted by use of a detachable positioning template. The invention includes methods for using the treatment system of the invention, and an applicator and a patient kit.

This invention provides a high-precision neurostimulation device and its control method. The device includes: stimulation modules connected to stimulation electrodes for applying electrical stimulation signals to the cerebral cortex; an interaction module for receiving user commands to enable user interaction; a main control module for receiving commands from the interaction module and driving the stimulation modules to output electrical stimulation signals; and a stimulation module for outputting high-precision electrical stimulation signals to each stimulation electrode, and through a preset channel control module, combining the stimulation electrodes in three configurations—cathode, anode, and electrode suspension—to form an M×N high-precision electrical stimulation. Based on traditional transcranial electrical stimulation technology, this invention improves the stimulation circuitry, making the channel states flexibly adjustable, achieving flexible and high-precision electrical stimulation with more pronounced stimulation effects and more precise stimulation sites. The high-precision electrodes can be combined in various ways, possessing strong scalability and meeting the needs of complex application scenarios.

A device includes a handle, an expandable structure including a plurality of splines extending from a proximal hub to a distal hub, a first electrode on a first spline of the plurality of splines, an outer tube extending from the handle to the proximal hub, and a shaft extending through the outer tube from the handle to the distal hub. The expandable structure has a collapsed state and a self-expanded state. The handle is configured to retract the shaft. Retracting the shaft may expand the expandable structure outward of the self-expanded state.

The invention relates to nerve stimulation equipment and a nerve regulation and control method, and the nerve stimulation equipment comprises an energy supply module which is used for providing energy for a signal output module; the signal output module is used for outputting ultrasonic signals of which the space peak sound pressure is 0.1 MPa to 0.5 MPa and the space peak time average sound intensity is 0.8 W / cm to 5.2 W / cm; the ultrasound signal is used to stimulate a target neuron. The device outputs large-range ultrasonic signals with the space peak sound pressure ranging from 0.1 MPa to 0.5 MPa and the space peak time average sound intensity ranging from 0.8 W / cm to 5.2 W / cm, the heterogeneity requirements of different brain regions can be met, and the problem that in the prior art, the heterogeneity requirements of different brain regions cannot be met is solved.