10 results about "Pain therapy" patented technology

2.1 A medical device comprising an invasive component with at least one electrode designed for positioning on a nerve and for emitting an electrical stimulation signal, and a signal generator connected to the electrode and designed to generate the stimulation signal, wherein the stimulation signal is designed to inhibit nerve excitation transmission, is known. 2.2 According to the invention, the at least one electrode is configured to emit an electrical control signal and the signal generator is configured to generate the control signal, wherein the control signal is configured to trigger a motor and / or sensory reaction, the expression of which depends on a distance between the electrode and the nerve. 2.3 Use in pain therapy using neurostimulation

This document discusses, among other things, systems and methods for managing pain of a subject. A system includes a first sensor circuit to sense a first signal indicative of a functional state of the subject, a second sensor circuit to sense a second signal different from the first signal, and a controller circuit. The controller circuit may determine an operating mode of the second sensor circuit according to the sensed first signal, trigger the second senor circuit to sense the second signal under the determined operating mode, and generate a pain score using at least the second signal sensed under the determined operating mode. The pain score may be output to a patient or used for closed-loop control of a pain therapy.

A neuromodulation device for functional rehabilitation and pain therapy (1, 100) is described, comprising a housing body (8, 108) and a housing cover (6, 106). within the housing body (8, 108), at least one electronic plate (7) being positioned, whereby the neuromodulation device for functional rehabilitation and pain therapy (1, 100), the electronic plate (7) comprising at least one control plate (71) equipped with at least one microcontroller for modulation function management, at least one actuator plate (72) equipped with at least one converter and an H-bridge, and at least one Wi-Fi module for connection with at least one sensor (14, 140) in order to forward data to an Artificial Intelligence module (201) and to at least one server (202).A stimulation and control system for functional rehabilitation therapy and pain therapy is also described, which is capable of collecting biomechanical data from the patient. This data is used for processing and calculations that assist a control subsystem in direct communication with the neuromodulation device for functional rehabilitation and pain therapy, enabling patient monitoring and adjustments of the neuromodulation device during therapy.

A medical device for use in the treatment of pain. 2.1 A medical device is known comprising an invasive component having at least one electrode configured to be positioned at a nerve and to emit an electrical stimulation signal, and a signal generator connected to the electrode and configured to generate a stimulation signal wherein the stimulation signal is configured to inhibit stimulation delivery of the nerve. 2.2 according to the invention, the at least one electrode is configured to emit an electrical monitoring signal and the signal generator is configured to generate a monitoring signal wherein the monitoring signal is configured to trigger a motor and / or sensory response, the form of which depends on the distance between the electrode and the nerve. 2.3 for the treatment of pain by means of nerve stimulation.

1. The name of the design product: intelligent pain treatment instrument. 2. The use of the design product: medical equipment combining electronic technology and physiotherapy, suitable for soft tissue injury, arthritis, neuralgia, etc. Different shaped electrode plates can be adapted to acupoint pressing or large area treatment. 3. The design points of the design product: in shape. 4. The picture or photo that best indicates the design points: perspective view 1.

A medical device for use in pain therapy includes an invasive component having at least one electrode configured to be positioned at a nerve and to emit an electrical stimulation signal. A signal generator is connected to the electrode and generates the stimulation signal. The stimulation signal is configured to inhibit stimulation transmission of the nerve. The at least one electrode is configured to emit an electrical monitoring signal. The signal generator is configured to generate the monitoring signal. The monitoring signal is configured to trigger a motor and / or sensory reaction, the form of which depends on a distance between the electrode and the nerve. The medical device can be used to apply neurostimulation in pain therapy.

The present invention discloses the use of a mRNA pain therapy to produce endogenous opioids for the treatment of temporary and chronic pain. In the preferred embodiment mRNA that encodes the production of B-endorphin, dynorphins A and B, and Nociceptin / Orphanin FQ, along with preferred packaging and administration options is disclosed.

Processing circuitry of a system configured to determine a patient state based on sensed signals including posture and activity information and control delivery of electrical stimulation therapy to the patient via electrodes implanted proximal to target tissue of the patient. The sensed signals also include impedance measurement, and other bioelectrical signals, where sensing is interleaved with the electrical stimulation therapy. Responsive to determining the patient state, select an action, wherein the selected action comprises one or more of: store collected information, upload the collected information to an external computing device, and output an electronic signal comprising an alert.

The utility model discloses a pain physical therapy device, relates to medical instrument technical field, the utility model discloses a pain physical therapy device, the utility model discloses a shell, the outer wall of shell is fixedly connected with a plurality of telescopic sleeve, the inner wall of shell is provided with massage mechanism, massage mechanism includes a plurality of massage machine, the outer wall of massage machine is connected with the shell in sliding mode, and the massage machine is connected with the shell in sliding mode. The massage machine comprises a shell, the outer wall of the shell is provided with a wearing mechanism, the wearing mechanism comprises a plurality of rotating sleeves, and the outer walls of the rotating sleeves are fixedly connected with a back protecting seat. Through the bolts, a user only needs to pinch a connecting rod and pull out the connecting rod upwards, the connecting rod drives the bolts to move, and then the massage machine is directly pushed out of the shell; after the massage machine needing to be replaced and the third telescopic base are inserted into the shell, the connecting rod and the plug pin are reset to clamp the massage machine so that the massage machine can be fixed, the different effects that the independent massage machine can be directly replaced to change massage physical therapy can be achieved, and the massage physical therapy requirements of different users under different conditions are met.

The invention belongs to the technical field of biological medicine, and particularly relates to the field of gene therapy and pain therapy. The invention provides an sgRNA and AAV-CRISPRi virus system for targeted inhibition of TRPV1 gene, the AAV-CRISPRi virus system is a CRISPRi system based on AAV delivery, and the core functional structure sequence of the AAV-CRISPRi virus system is a 5 '-ITR inverted repeat sequence, an EF1 alpha core promoter, a ZIM3 transcription inhibition structural domain, a linker, a sadCas9-NLS nuclear localization signal-SV40 poly (A) termination signal-U6 promoter, and an sgRNA-3'-ITR inverted repeat sequence, according to the core functional structure, the miniaturization of a CRISPRi system is realized, and the infection success rate and the target gene inhibition efficiency are improved while the plasmid construction and AAV packaging costs are reduced. The AAV-CRISPRi virus system for targeted inhibition of the TRPV1 gene is used for preparing drugs for chronic pain, and has the characteristics of high efficiency, strong specificity and few side effects.